Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Brenda Nakimuli Luswata
ID: UNCST-2021-R013228
 Refining the programme theory for realist inquiry on adolescent SRH accountability in disadvantaged urban areas: macro and meso-contextual drivers and social mechanisms. Case studies Uganda and Benin
REFNo: SS1032ES

(4) To develop guidance on accountability for adolescent girls living in urban slums and methodological guidance for realist evaluation of complex problems. (Work package 4),To develop an overarching programme theory (Work package 3),To test and refine the initial programme theory grounded in case studies conducted in two urban poor neighborhoods in Delhi and Mumbai, India ; Kampala, Uganda and Cotonou, Benin (Work package 2),To develop the initial programme theory on accountability towards adolescent girls living in urban slum, based on the MRT and existing imperical literature on accountability in sexual and reproductive health in an urban and rural health system (Van Belle, 2014, Van Belle & Mayhew, 2016; Van Belle et al. 2018),To contribute to a better understanding of the causal chain underlying accountability in sexual and reproductive health towards adolescents living in urban slums in LMIC. The,
 Uganda 2021-10-25 2024-10-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Erume
ID:
Antimicrobial resistance in zoonotic pathogens – a challenge for urban small holder livestock production system
REFNo: A156ES

1. To determine the burden of campylobacter infections in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
2. To determine management and risk factors which underlie the dynamics and perpetuation of in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
3. To establish the poultry farmers and traders’ knowledge, attitudes and practices related to AMR campylobacter strains and antibiotic usage at poultry farms.
4. To establish the AMR of campylobacters strains from the poultry phenotypically and molecularly including whole genome sequencing (WGS).

 Uganda 2021-10-25 2024-10-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Steven Odongo
ID: UNCST-2021-R013336
 DEVELOPMENT AND VALIDATION OF MULTIPLEXED LATERAL FLOW ASSAY FOR DETECTION AND DIFFERENTIATION OF SARS COV-2 FROM OTHER HUMAN CORONAVIRUSES
REFNo: HS1706ES

(1) Track levels of conservation of SARS CoV-2 structural proteins based on nucleotide sequences published in the Global Initiative on Sharing All Influenza Data (GISAID) database by sequencing laboratories in Uganda, (2) Identification and production of specific but conserved SARS-CoV-2 marker protein (s) capable of distinguishing SARS-CoV-2 from other hCoVs, (3) Develop a Nanobody (Nb) based multiplex LFA device targeting the marker proteins, and (4) Validate the performance characteristics of the LFA in a laboratory setting on archived sera.
 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Jordans
ID: UNCST-2020-R014861
 Evaluating the effectiveness of Can’t Wait to Learn in formal education in Uganda
REFNo: SS1024ES

1)To assess the feasibility of the intervention and study (cRCT) methods, 2)To evaluate the effectiveness of CWTL in improving reading and numeracy outcomes of children in Primary 3 (P3), 3)To assess the value for money of CWTL and other factors for EdTech programme scale-up.
Netherlands 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Nattabi Kigongo
ID:
Vanishing Glaciers of the Rwenzori Mountains National Park (Uganda)
REFNo: NS291ES

Vanishing Glaciers project aims for the first
time to explore the streams of mountain
biogeochemistry, and the living
microorganisms of these remote
ecosystems, now strongly impacted by
climate change.
The project’s main goals are:
• To establish the census of microbial
life of the world’s glacier-fed
streams.
• To predict the future changes of the
glacier-fed streams biogeochemistry
as the world’s glaciers recede

1. Study the microbial life from glacier-fed streams
2.Study the biogeochemistry of glacier-fed streams
3.Study the environment of glacier-fed streams, including glaciological parameters
 Uganda 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Performance of a novel, rapid AI-driven screening tool for improved COVID-19 patient care and management in Uganda
REFNo: SIR74ES

General Objective
To develop and deploy AI-driven screening tools for improved care and management of COVID-19 patients. This will be achieved through the following specific objectives:
Specific Objectives
1. To collect, curate and label Lung Ultrasound (LUS) images from COVID-19 patients and patients with related pulmonary pathologies such as non-COVID-19 derived pneumonia, yielding a generalizable and representative image/video dataset.
2. To develop robust image-driven machine learning (ML) models for detection and screening of COVID-19 using the data from objective 1.
3. To build mobile and web-based applications that integrate the ML models, for online (real-time) and offline COVID-19 screening.
4. To pilot the developed applications and evaluate their clinical efficacy in COVID-19 screening.

Uganda 2021-10-22 2024-10-22 Engineering and Technology Non-Clinical Trial Non-degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
 Identification and characterization of Diabetes in low-resource Populations
REFNo: HS1791ES

The secondary study objectives are:
1. To establish a base-line cohort of well-characterised people with diabetes to understand disease progression of the different phenotypes, including uptake and response to treatment.
2. To identify and recruit a cohort of non-diabetic volunteers (including prediabetes i.e., at high risk of developing diabetes) for longitudinal follow-up.
i. To identify a cohort of non-diabetic people in order to measure the incidence of disease in the future estimate incidence of diabetes.
ii. To assess the burden and rates of progression of vascular complications associated with the different phenotypes of dysglycaemia.
Malawi 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frederick Mubiru Edward
ID:
Market Research on User Perspectives for a 4-month Depot Medroxyprogesterone Acetate Subcutaneous (DMPA-SC) Product
REFNo: HS1792ES

1. To solicit input from potential and current contraceptive injectable users, as well as males/partners, on acceptability and implications for having multiple injectable products of different durations in the market, with an emphasis on a 4-month DMPA-SC product as well as a potential 6-month injectable
2. To co-create marketing strategies/messages with current and potential users for the introduction and differentiation of new injectable products

 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josef Bryja
ID:
Evolutionary diversity of small mammals in isolated mountains in north-eastern Uganda - stepping stones for colonization of the Albertine Rift and Kenyan Highlands from Ethiopia?
REFNo: NS301ES

Overall goal: To analyse genetic diversity of small mammals and their pathogens to test alternative hypotheses of colonization of Eastern Afromontane Biodiversity Hotspot (EAMBH)
Objective: Description of biodiversity patterns in EAMBH using integrative approach

Output 1: List of small mammals of isolated sky islands of north-eastern Uganda
Activity 1: Field sampling, species identification (using integrative approach)

Output 2: Phylogeographic scenarios for the colonization of EAMBH, identification of "refugia within refugia", biogeographical regionalization
Activity 2: Combination of obtained (genetic) data with other datasets from Ethiopia, Kenya, Tanzania, etc. Testing of phylogeographic hypotheses.

 Czech Republic 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Strengthening the Effectiveness of National Children’s Care Systems: A Political Analysis of Uganda
REFNo: SS1064ES

This study will examine the effectiveness of the National Children’s Care System in Uganda focusing on the political, bureaucratic and economic forces as well as the strategies that augment the effectiveness of this system.

The study aims to use the collected data to develop an adaptable framework to achieve effective national care systems for children in Low-Income Countries (LICs).

In specific terms, the research will:
1. Examine the political, bureaucratic and economic forces shaping the effectiveness of Uganda’s national children’s care systems

2. Delineate the strategies to improve the capacity of these systems to protect children

3. Develop an adaptable framework for Uganda to analyze factors shaping children’s care systems in LICs?
 Uganda 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gorretti Nassali
ID:
Trends of Breast Cancer among patients younger than 40 years at St. Francis Hospital Nsambya: A cross section descriptive study
REFNo: HS1758ES

This study aims to describe prevalence by age, stage at diagnosis, cancer type and grade, and hormone receptor status, among women younger than 40 years at St. Francis Hospital Nsambya between 2010 and 2020.
 Uganda 2021-10-21 2024-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anna Ritah  Namuganga
ID:
Mycobacterium tuberculosis associated immune activation and exhaustion profiles for prediction of active pulmonary tuberculosis
REFNo: HS1201ES

Main Objectives
Determine the differential expression of immune activation and exhaustion markers to predict active TB disease among presumptive TB cases.
Primary Specific Objectives
i. To determine the levels of soluble markers of immune activation and exhaustion in serum of active PTB cases, LTBI and those with ORDs and response to treatment.
ii. To determine levels of immune activation and exhaustion associated cytokines/chemokines in serum among active PTB, LTBI and ORDs and response to treatment.
iii. Perform a phenotypic profiling of expression of markers immune activation and exhaustion in PBMCs and determine their association with active PTB, LTBI states or other respiratory diseases (ORDs).
iv. To determine the activation and exhaustion genes expression profiles in QFT Gold plus cell pellets and compare levels in active PTB cases and LTBI.

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Degree Award
Andrew Okwi Livex
ID: UNCST-2021-R013180
 Unlocking the potential of thiocyanate in cassava root for management of painful crisis in sickle cell disease patients in Uganda
REFNo: HS1486ES

1. To determine the frequency of cassava consumption in the districts of Uganda with high prevalence of sickle cell disease
2. To assess the frequency of painful crisis among SCD patients in these districts.
3. To determine the levels of thiocyanate in patients with SCD in these districts
4. To determine the optimum concentration of thiocyanate that causes antisickling (in vitro studies)

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Khamisi Musanje
ID: UNCST-2021-R012863
 Acceptability, Feasibility and Effectiveness of a Mindfulness based Intervention to Promote Adherence to Antiretroviral Therapy among Adolescents in Kampala.
REFNo: HS1656ES

1. To adapt and explore acceptability of ACT-DNA-v among users (ALWHA) and providers (HCPs).
2. To measure feasibility of the adapted ACT-DNA-v for use with ALWHA.
3. To examine the impact of ACT-DNA-v on reducing proximal psychosocial barriers to medication adherence (depression, anxiety and stigma) among ALWHA.
4. To measure effectiveness of a mindfulness based intervention (ACT-DNA-v) on self-reported adherence among ALWHA in Kampala, and ascertain its impact on viral load reduction via analysis of data from medical records

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
 SEVERE PNEUMONIA IN CHILDREN: THE ABILITY OF BODY COMPOSITION TO PREDICT SURVIVAL, AND THE EFFECT OF NUTRITIONAL SUPPLEMENTATION ON OUTCOMES
REFNo: HS1719ES

4. To determine the effect of a nutritional intervention (RUTF) on clinical outcomes (post discharge mortality, re-admission, and occurrence of severe acute malnutrition) of children hospitalized for severe pneumonia.,3. To determine the effect of a nutritional intervention (RUTF) on fat and muscle mass in children hospitalised for severe pneumonia.,2. To compare the ability of various muscle and fat mass indices to predict survival in children hospitalised for severe pneumonia.,1. To describe the role of nutritional status on outcomes following hospitalization for severe pneumonia among children.,To describe the relationship between muscle and fat mass and survival, and determine the role of nutritional supplementation on fat and muscle mass, and on treatment outcomes of children hospitalized for severe pneumonia,
 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 A Public Health Approach to Cervical Cancer Prevention in Uganda
REFNo: HS1727ES

Aim 1. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based cervical cancer screening program.

Aim 2. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based HPV vaccination program.

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Adakun
ID:
Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES

Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives

1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology


2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sandra Lamwaka
ID:
TOWARDS A NEWS INDUSTRY FRAMEWORK FOR TACKLING THE VICE OF BROWN ENVELOPE JOURNALISM: PERCEPTIONS OF JOURNALISTS AND PUBLIC RELATIONS PRACTITIONERS IN UGANDA
REFNo: SS1014ES

1. To examine journalists and PR practitioners’ perception of the brown envelope. 2. To identify the various forms that BEJ takes in Uganda. 3. To find out journalists and PR practitioners' perceptions on why BEJ is prevalent and enduring in Uganda. 4. To find out journalists and PR practitioner's perspectives on the policies that the media industry can employ to address the practice of BEJ in Uganda.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
JANISCH Judith Judith
ID:
Ecological influences on Locomotor Performance in Free-Ranging Primates: a phylogenetic investigation
REFNo: NS299ES

- to investigate the evolution of arboreal locomotion in primates and discern which aspects of the arboreal environment most directly influence their locomotor performance.
- to describe kinematics of different primate species (Cercopithecus mitis, Cercopithecus ascanius, Cercopithecus lhoesti, Chlorocebus aethiops,
Lophocebus albigena, Papio anubis, Colobus guereza and Piliocolobus badius) in
their natural habitat and analyze the variation in a phylogenetic context.

 Austria 2021-10-19 2024-10-19 Natural Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
 Exploration of the Virologic Characteristics of Recently Transmitted HIV-1 Viruses in Uganda and Kenya
REFNo: HS1635ES

1. To identify key unique molecular features of T/F virus strains and characterize them
2. To relate these unique genetic features to viral protein structures and in vitro virus phenotypes.
3. To determine the difference between HIV-1 co-receptor usage of the T/F virus variants and NT virus strains.
4. To determine particle infectivity of T/F virus strains in comparison to that of the NT virus strains.
5. To compare the resistance of T/F virus strains to the antiviral effects of type I interferons to that of the NT strains
6. To determine the sensitivity of T/F virus strains to broadly neutralizing antibodies in comparison to the non-transmitted virus strains.
 Uganda 2021-10-15 2024-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noah Kalengo
ID:
LIVED EXPERIENCES OF UNCIRCUMCISED POKOT WOMEN IN AMUDAT DISTRICT
REFNo: SS1046ES

To explore the characteristics of uncircumcised Pokot women in Amudat District.

To explore the psychosocial experiences of uncircumcised Pokot women in Amudat District.

To analyze the protective factors/coping resources among the uncircumcised Pokot women that enable them to survive despite their experiences.

 Uganda 2021-10-15 2024-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Feasibility and acceptability of integrating PrEP and safer conception messaging into assisted partner notification
REFNo: HS1625ES

To examine the feasibility and acceptability of integrating gain-framed vs. loss-framed messages on PrEP and safer conception into the assisted partner notification (APN) program in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Smart Triage + QI: A digital triaging platform to improve quality of care for critically ill children
REFNo: HS1745ES

To identify and examine opportunities for ongoing improvement to strengthen the health system. ,To enable healthcare workers to recognize the most urgent children more rapidly and allocate existing resources more efficiently,To implement Smart Triage + QI to improve the quality of care at three UCMB health care facilities and Gulu Regional Referral Hospital (a government facility). ,
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Uganda Paediatric and Adolescent HIV Cohort on Antiretroviral Therapy: Study Protocol (UP-ART)
REFNo: HS1699ES

The objectives of this study are to:
1) Describe the characteristics of children and adolescents living with HIV receiving paediatric care in the participating centres and coverage of ART
2) Describe the uptake of new antiretroviral drugs such as DTG across age groups and regions
3) Assess the effectiveness and safety of new antiretroviral drugs such as DTG, including viral suppression, incidence of adverse events, serious adverse events and discontinuation of drug
4) Assess broader clinical outcomes including retention in care, mortality, disease progression, immune response, viral suppression, overall and by age and treatment regimen/treatment history
5) Assess (i) the prevalence of HIV drug resistance among children/adolescents start of treatment and the impact on treatment response, and (ii) among those who experiencing virological failure on DTG to describe the risk of accumulation of drug resistance (see sub-study Section 4).

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Integration of phone-based data capture tool to support real-time reporting and quality assurance of SARS-CoV-2 Ag RDT in Uganda
REFNo: HS1723ES

1. To pilot the integration of phone-based data collection tool and real-time reporting via a dashboard
2. To monitor quality and post-market surveillance of the Ag RDT in Uganda
3. To demonstrate the use of remnant Ag RDT samples in the routine surveillance of SARS –CoV-2 variants in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Use of mobile Text Messaging Service information for mothers in situations of limited access to physical antenatal and postnatal services during the COVID-19 Pandemic
REFNo: HS1732ES

1. To elicit requirements for incorporating maternal and child health educative messages into the developed mobile-based transport technology for mothers.
2. To incorporate maternal and child health educative messages into the developed mobile-based transport technology for mothers.
3. To evaluate the usefulness of the information to the mothers through the mobile Text Messaging Service.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 Nurse-led PrEP Delivery for Young Women Attending Family Planning Clinics in Uganda
REFNo: HS1740ES

Aim 1: To evaluate the feasibility and acceptability of nurse-led PrEP delivery to adolescent girls and young women attending a family planning clinic in Uganda.

Aim 2: To assess PrEP persistence among adolescent girls and young women receiving nurse-delivered PrEP at a family planning clinic.

Aim 3: To compare the characteristics of adolescent girls and young women who accept with those who decline PrEP and those who persist with those who discontinue PrEP at a family planning clinic in Uganda.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Utility of a Liquid Blood Biopsy for Non-invasive Lung Cancer Diagnosis and Biomarker Testing at Uganda Cancer Institute.
REFNo: HS1743ES

1. To compare ctDNA sequencing to standard histopathologic diagnoses of lung cancer in patients with advanced stage lung cancer at the Uganda Cancer Institute (UCI).

2. To describe the tumor-specific molecular alterations present in lung cancer specimens and ctDNA in advanced stage lung cancer patients at UCI.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
 Childhood victimization and mental disorders among adolescents of sex-working and non-sex working mothers in post-conflict Gulu city in Northern Uganda - a cross-sectional study
REFNo: HS1769ES

The main goal of this study is to provide the evidence needed by the health care programmers and policymakers to inform appropriate policies and practices on prevention, screening, and management of victimizations among adolescents in Uganda. Specifically, the following are the study objectives:
1. To determine the prevalence of childhood victimization among adolescents.
2. To examine the relationship between sociodemographic characteristics and general health and childhood victimization among adolescents.
3. To examine the relationship between maternal sex work status and childhood victimization.
4. To examine the relationship between maternal major depression and childhood victimization among adolescents.
5. To determine the prevalence of selected childhood mental disorders among adolescents.
6. To examine the relationship between exposure to childhood victimization and childhood mental disorders in post-conflict Gulu City.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Interrupting HIV and TB Stigma in the Household during TB Contact Investigation in Uganda
REFNo: HS1788ES

This project aims to evaluate the effects of a complex intervention on household HIV stigma and uptake of HIV testing among household members undergoing TB contact investigation.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the impact of the COVID-19 pandemic restrictions on HIV care in Kampala, Uganda: a propensity-score matched and difference-in-differences analysis
REFNo: HS1709ES

Primary objective: To evaluate the impact of the COVID-19 pandemic restrictions on linkage to care, time to linkage, timely ART initiation, retention in care, viral load suppression, and mortality among people living with Human Immunodeficiency Virus (PLHIV) in the Kampala Capital City Authority (KCCA) health facilities in central Uganda

Secondary objective: To document and synthesize measures for continuity of service delivery for PLHIV during the COVID-19 pandemic
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty  Nambuusi Bukenya
ID:
Youth Wellbeing Champions: Piloting community-based, youth peer-led mental health and wellbeing support for young people in Uganda
REFNo: SS956ES

Study goal: To generate evidence around the effectiveness of a pilot community-based and responsive wellbeing / mental health intervention led by young people with lived experience of care and supported by social work practice/practitioners in Uganda. Specific objectives 1. Assess the level of knowledge and understanding of a trauma-informed approach to addressing mental health needs among social workers based on the Kirk Patrick pre-post questionnaire. 2. Assess the prevalence of clinical mental health, well-being, self-esteem/ self-worth, and depression symptoms among children and youth based on the WHO-5 / PHQ-9 and Rotter’s Locus of Control. 3. Examine the level of knowledge of mental health literacy, resilience, psychosocial support, and wellbeing practice among care leavers based on Kirk Patrick's pre-and post-assessments questionnaire.
Uganda 2021-10-12 2024-10-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Youth Health SMS: Using mobile technology to prevent HIV and related Youth Health problems: Sexual health, Mental health, and Substance use in southwest Uganda
REFNo: SS969ES

This study will result in the development of one of the first mobile phone-based interventions for Adolescents and Young Adults (AYA) in East Africa that begins to address the co-morbid HIV risk factors of sexual health, mental health, and alcohol use. AYA is a developmental period associated with the increased importance of peers, increased technology use, increased mobility, initiation of sex, emergence of mental health disorders (if at risk), and initiation of alcohol use. Consequently, AYA is a critical time for preventive interventions. Poor mental health and alcohol abuse are associated with increased risk for HIV infection. Thus, the proposed research will attempt to address these areas concurrently.

The proposed research will evaluate if adapting and updating the existing free and nationally available text message and interactive voice recognition (IVR) service included in *161 that was initially developed by FHI 360. Our work will test and tailor messages for AYA to disseminate pre-exposure prophylaxis (PrEP) information and pilot specific mental health and hazardous alcohol use screens. Symptomatic AYA will be referred to behavioral health counselors for further assessment and treatment as needed. AYA today rely heavily on mobile phones for information and services, thus we believe the proposed intervention could be applied and adapted across the region, and potentially in other under-resourced settings.

We will conduct formative research to evaluate and adapt an existing text-message and interactive voice recognition (IVR) platform. We will then pilot the new menus and examine if using this platform promotes HIV prevention (pre-exposure prophylaxis (PrEP), HIV testing, safer sexual behaviors) and increases mental health and alcohol use screening and linkage to counselors as needed for adolescents and young adults (AYA) in a rural Ugandan region with high HIV seroprevalence and limited resources.

2. State the study objective(s) and research question(s)
Aim 1: To adapt an evidence-based mobile phone-delivered sexual health program, to include PrEP information and deliver mental health and alcohol use assessments with the goal of increasing screening and referral, as well as linkage to counselors for AYA at HIV risk.

Aim 2: Evaluate through a pilot RCT (N=126 AYA, 15-19 years) intervention (a) acceptability and feasibility, and (b) impact on uptake of HIV prevention strategies, as well as screening and linkage to mental health and alcohol use school-based counselors.

 Uganda 2021-10-12 2024-10-12 Social Science and Humanities Clinical Trial Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Mortality Surveillance Activity Protocol All-cause Mortality Surveillance in Bunyangabu, Kabarole and Kyenjojo districts, Uganda
REFNo: HS1755ES

the objective of establishing a mortality surveillance system is to enumerate and document all-cause mortality in the 3 districts of Bunyangabu, Kabarole, and Kyenjojo in Uganda. Specifically this will; a) determine HIV/AIDS related and proportionate mortality rate in the three districts, b) determine maternal and neonatal mortality rates in the three districts c) identify causes of death among HIV patients and causes of pregnancy-related deaths in the three districts and d) document the implementation process of mortality surveillance in order to inform future scale up.
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waruiru Kolff Kayla Tinie
ID: UNCST-2021-R012291
 Turn-taking interactions in Eastern male Chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS295ES

Understanding the turn-taking systems of chimpanzees and how this relates to human language and it's origins. Hence, whether the turn-taking systems of chimpanzees are influenced by interpersonal contexts (social bonds & dominance rank).
 Netherlands 2021-10-12 2024-10-12 Natural Sciences Non-Clinical Trial Degree Award
ALEX NDYABAKIRA
ID:
Assessing use of SolarSack for treatment of safe drinking water in Uganda
REFNo: HS1680ES

1. To determine the willingness to buy and acceptability of SolarSack water treatment device
2. To determine the most appropriate cost per unit for SolarSack for rural, peri-urban and urban settings
3. To explore user preferences for the SolarSack device
4. To determine the effect of SolarSack use on prevalence of waterborne diseases

 Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phyllis Kisa
ID: UNCST-2023-R007952
 SURGICAL NEONATES IN A LOW-RESOURCE SETTING: AN AUDIT OF NUTRITION AND OUTCOME
REFNo: HS1736ES

To audit our current the nutritional regime among newborns with gastro-intestinal anomalies admitted to the Paediatric Surgical Unit at Mulago National Referral Hospital(MNRH).
Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tukwasiibwe Moses
ID:
Impact of forced displacement on labour markets in Uganda
REFNo: SS1039ES

Objective 1) Provide strong empirical evidence of the direct and indirect impacts. Against the backcloth of a comprehensive literature survey, and investigating non-camp urban refugee populations in Kampala and as well as camp based refugees in Nakivale refugee settlement in Uganda.

Objective 2) Identify the mechanism(s?) through which impacts occur. Analyzing the empirical evidence we will: i) explore direct and indirect (partial equilibrium) impacts and outcomes on the dynamics of labor market and business behavior, assessing impact-attribution and correlating variables such as labor supply and wages, capital investment/ labor trade-offs and demand side factors, productivity and skills, national and international investment patterns; ii) assess the role of political economy, regulatory and policy frameworks; iii) generate qualitative analysis of household and individual livelihood/life course experiences in relation to labor market outcomes, iv) generate local, national and comparative findings.

Objective 3) Support the development of evidence-based, effective, and context-specific jobs policy advice. The analytical outputs will provide a robust evidence base for jobs policy advice envisaged at different levels (local, national, and international), and for different stakeholders (e.g. municipal and national governments, donors, intergovernmental and non-governmental organizations, private sector investors, entrepreneurs and SME sector, and displaced and host populations). Policy advice will include, inter alia: finance and investment strategies, regulatory framework e.g. rights to work/rights at work and employer conditions for decent work), spatial planning, training and skills, role of investment incentives, socio-economic policies for displaced and host populations vis à vis labor markets.

Objective 4) Generate new data that will be in the public domain for use in further research. The proposed study will generate new statistical (survey) data sets for three of the four case countries: Colombia, Ethiopia and Uganda. In Jordan, the study team is already in possession of sufficient data through previous surveys conducted by Fafo and partners. When designing the new surveys, special attention will be given to establish robust baselines that can be applied in future impact analyses. Responding to this objective and the general TOR requirements, we shall place all the data generated in the proposed project in the public domain.

Uganda 2021-10-11 2024-10-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
PETER OMASWA
ID:
Relevance and Factors Affecting Exchange of Plant Material and Data to Conservation
REFNo: NS156ES

General Objective
To assess the importance of plant material and data exchange between African and European Institutions for conservation.

Specific Objectives
1. To review the extent to which plant material and data are exchanged between African and European institutions.

2. To evaluate the opportunities and constraints to plant material and plant data exchange between African and European Botanical Institutions.

3. To evaluate the proportion of exchanged plant material and data translated into conservation applications.


 Uganda 2021-10-08 2024-10-08 Natural Sciences Degree Award
Carolyn Nakisige
ID:
Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
REFNo: HS1372ES

1. To evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women.
2. Determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
 EXPERIENCES OF LIVING WITH OBSTETRIC FISTULA AMIDST COVID -19 PANDEMIC IN EAST AND CENTRAL UGANDA: Qualitative study.
REFNo: HS1464ES

General Objective
To document the experiences of living with fistula amidst the COVID-19 pandemic among women who developed OF during corona virus pandemic, those who had fistula and had started seeking for care, those who were repaired and were at the stage of reintegration and those declared as incurable between 15-49 years of age from Eastern and Central Uganda

Specific objectives

1) To document participant’s awareness about COVID 19 Pandemic

2) To explore the perceptions of women living with OF amidst COVID 19 Pandemic

3) To explore the effect of COVID -19 on the livelihood of women with OF.

4) To explore experience in accessing fistula services among women reintegrating and screened for surgeries during the COVID-19 pandemic.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Aging with HIV: Experiences and challenges of older adults 50 years and above living with HIV
REFNo: HS1759ES

3. To explore determine the challenges faced by older adults 50 years and above aging with HIV.,2. To describe the experiences of older adults 50 years and above aging with HIV.,The goal of this study is to explore the experiences, perceptions, and challenges of older adults 50 years and above aging with HIV.,
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Kalyegira
ID:
The Role of Basic Psychological Needs Satisfaction for the Psychological Wellbeing and Social-Cultural integration of Refugees in Rhino Camp Refugee Settlement, Uganda
REFNo: SS905ES

• To estimate the relationship between the three psychological basic needs satisfaction (Autonomy, relatedness and competence) to the psychological wellbeing of refugees.
• To determine whether the basic psychological needs satisfaction influences refugee integration.
• To find out what factors influence the need satisfaction/frustration for refugees and how?
• To estimate whether physical and psychological need satisfaction interact in an “unprepared to benefit” or “buffering against adversity” direction?

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
John Byabagambi Bekiita
ID:
Ability and willingness to pay for voluntary medical male circumcision in Uganda: A mixed-methods study
REFNo: HS1523ES

1. To identify the factors that determine the ability to pay for VMMC in Uganda.
2. To determine the factors associated with willingness to pay for VMMC services in Uganda.
3. To find out the reasons that inform the choice of either the willingness to pay or not to pay for VMMC services in Uganda.

 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Pandmic-related disruptions in HIV care among adolescents and young adults with HIV (AYAWHIV) and the potential for mHealth interventions.
REFNo: HS1686ES

To examine the effects of the COVID-19 restrictions on HIV treatment of AYALWHIV and assess the potential of mHealth intervention in bridging these disruptions.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Transactional sex and HIV among men in Rakai, Uganda
REFNo: SS984ES

The overall goal of this research is to understand the characteristics of men who engage in transactional sex and the causal pathways that lead from transactional sex to incident HIV in Rakai, Uganda.
• Aim 1. To measure perceptions, content validity, and response processes of transactional sex measures in the Rakai Community Cohort Study
• Aim 2. To examine men’s experiences in transactional sex relationships and factors that may heighten risk for HIV

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Stamps Sarah
ID: UNCST-2019-R001036
 Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS294ES

Investigating the physics of strain accommodation in the magma-poor Albertine- Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 USA 2021-10-08 2024-10-08 Natural Sciences Non-Clinical Trial Non-degree Award
Marsiale Kamugisha
ID:
'Analysing the Impact of Transformative Governance and Agroforestry on Household Food Security in Southwestern Uganda'
REFNo: A130ES

1)To assess contributory factors responsible for determining household transition to food security.
2)To evaluate the household governance system that enhances agroforestry-based food security.
3)To assess households’ potential benefits of agroforestry beyond food security.

Uganda 2021-10-06 2024-10-06 Agricultural Sciences Non-Clinical Trial Degree Award
Nadine Schubert
ID:
Genetically-based social communication in an inbred group-living wild mammal
REFNo: NS273ES

The aim is to investigate the role of immune genes of the major histocompatibility complex (MHC) in affecting odour cues used for social communication in banded mongooses. Furthermore, we want to investigate the link between MHC composition of an individual and fitness parameters as well as the impact of the MHC on microbiota communities. Last, it is crucial to test the ability of banded mongooses to discriminate MHC-based differences in odour cues in a natural setting.
 Germany 2021-10-05 2024-10-05 Natural Sciences Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Clinical Predictors of 3-Months Isoniazid Rifapentine (3HP)- Related Adverse Drug Reactions (ADR) During Tuberculosis Preventive Therapy (PAnDoRA-3HP study)
REFNo: HS1582ES

Primary Objectives
1.To describe the safety profile of 3HP among people receiving tuberculosis preventive therapy.
2.To describe the effect of adverse drug reactions on tuberculosis preventive therapy completion rates
Secondary Objective
1.To describe the pharmacokinetic and pharmacogenomic determinants of ADRs among people receiving tuberculosis preventive therapy in Uganda
2.To determine the efficacy of 3HP when used for tuberculosis preventive therapy.

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Multicenter, Randomized, Double-Blind, PlaceboControlled Trial of the Safety and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Outpatients in Early Stages of COVID-19
REFNo: HS1715ES

Primary Objective
Primary objective: Among outpatients with recently diagnosed SARS-CoV-2 infection to compare the safety and efficacy of a single infusion of hIVIG (pooled for the 2 hIVIG

products) versus placebo, each given with SOC, on clinical status after seven days. Two hypotheses will be tested to address this primary objective, which compares the primary endpoint among two study populations: 1) participants where neutralizing MAb was not specified as part of SOC treatment (stratum 1, see Section 6.1 Overall Study Design); and 2) all randomized participants (stratum 1 and stratum 2 combined). hIVIG will be considered superior to placebo if either of the two hypotheses are rejected.
Secondary Objectives and Endpoints
Secondary objectives, including subgroup analyses and safety outcomes, will be addressed for all randomized participants and for those in stratum 1 and 2 separately.
Secondary Endpoints
The clinical status as classified on the ordinal outcome scale will be assessed with a number of additional analyses comparing hIVIG (pooled for the 2 hIVIG products) with placebo, among the overall study population as well as for the key subgroup of those not receiving anti-SARS-CoV-2 monoclonal antibodies as part of SOC (stratum 1), including:
1. All-cause hospitalization or death through 28 days.
2. All-cause mortality through 28 days.
3. Significant disease progression through 28 days, using a time to event analysis with outcome defined by fulfilling criteria for category 4 or 5 on the ordinal scale.
4. Distribution of ordinal scale outcome at Day 4, 14, and 28.
5. The proportion of participants with any disease progression at Day 7, using a sliding dichotomous scale progression defined by a categorization on the ordinal scale that is worse than the status at entry

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joyce  Nankumbi
ID:
The status of OFSP production, utilization and the nutritional status and welfare of sweet potato growing households in northern and eastern Uganda
REFNo: A152ES

1. To characterise the consumption of vitamin A rich foods among households in the selected northern and eastern districts of Uganda 2. What is the food security status in the households in the selected northern and eastern districts in Uganda? 3. To document the production and consumption of orange-fleshed sweet potato among households in the selected northern and eastern districts in Uganda? 4. To identify infant feeding practices of women in the selected districts of northern and eastern regions in Uganda? 5. To identify water, hygiene and sanitation practices of households in the selected northern and eastern districts in Uganda 6. To establish the knowledge, attitudes and perception on the consumption of beta carotene-rich orange-fleshed sweet potatoes/ vitamin A-rich foods among households in the northern and eastern regions in Uganda,To determine status of orange-fleshed sweet potato production, utilization and the nutritional status and welfare of sweet potato growing households. in northern and eastern Uganda ,
 Uganda 2021-10-01 2024-10-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Arthur Nuwagaba
ID:
TOP MANAGEMENT TEAM CHARACTERISTICS AND PERFORMANCE OF UGANDAN STATE AGENCIES
REFNo: SS999ES

iv. Establish the joint effect of top management team characteristics, strategy implementation and external environment on the performance of Ugandan state agencies.,iii. Determine the moderating effect of the external environment on the relationship between top management team characteristics and the performance of Ugandan state agencies.,ii. Establish the mediating effect of strategy implementation on the relationship between top management team characteristics and performance of Ugandan state agencies.,i. Determine the influence of top management team characteristics on the performance of Ugandan state agencies.,The main objective of the study is to determine the influence of strategy implementation and external environment on the relationship between the TMT characteristics and the performance of state agencies in Uganda.,
 Uganda 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Degree Award
Wang Vibeke
ID:
Supporting Parenting Care Corners in Markets to Reduce Unpaid Care Work for the Vulnerable Business Women in Uganda
REFNo: SS944ES

1. To deepen the evidence base on whether and how reducing women’s unpaid childcare burden increases their productivity and income.
2. To examine the factors that impede access to parenting care facilities among vulnerable women engaged in business markets in Uganda and how these could be mitigated.
3. Evaluate the effects of parenting care facilities, financial subsidy and parents’ training on the productivity of mothers and profitability of their businesses.
4. To inform government action through tested and proven models for scaling up parenting care corners to both structured and unstructured markets
5. To provide proof of concept on how governments can introduce affordable, effective, and sustainable childcare models that work for vulnerable mothers who work in informal markets in Uganda.

Norway 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aida Cuni Sanchez
ID:
Monitoring forest dynamics in Bwindi National Park
REFNo: NS282ES

• Does tree growth change with increasing altitude?
• How do taxonomic, forest structural and environmental attributes affect tree growth?
• How do carbon stocks change over time at different altitudes?

 Spain 2021-10-01 2024-10-01 Natural Sciences Non-Clinical Trial Non-degree Award
Radhika Sundararajan Lu
ID:
A pilot study of adherence support delivered by informal health providers to improve entry to and retention in HIV care in rural Uganda
REFNo: HS1747ES

: Pilot test the adapted intervention to evaluate implementation and impact on linkage/retention in HIV and ART adherence among individual PLWH,Adapt an evidence-based layperson adherence support curriculum for delivery by TH.,
 USA 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Evaluation of Clinical Chemistries from Biospecimens Collected with a Painless Capillary Blood Collection TASSO SST Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1751ES

We plan to compare capillary chemistry values collected via the painless Tasso collection device to standard serum chemistry values collected via venipuncture at a single study visit (Day 28 of the main study(HS 2292)) for each consenting participant. We plan to evaluate the correlation between chemistry values from capillary versus venous blood collection and identify any scenarios where the values diverge such as for high or low values or for specific analytes collected in a remote field location. We plan to review the failure rate and causes for failure for the Tasso device
 Uganda 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Ntaro
ID: UNCST-2020-R014133
 Effect of student community engagement on sanitation behavior: a case of Community Led Total Sanitation in Kabale District
REFNo: HS1135ES

To evaluate the effect of students community engagement on household level ODF status in Kabale District, Uganda so as to demonstrate the contribution of students in improving CLTS implementation and outcomes
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Infant extended safety follow-up study – an observational study of brain imaging and child development in infants (DolPHIN-2 PLUS)
REFNo: HS1639ES

1. To determine if there are developmental differences following exposure to DTG or EFV. 2. To examine brain structure and microstructure of HEU children. 3. To determine developmental outcomes. 4. To validate the Hyperfine, low-field MRI system 5. To explore the impact of environmental factors such as antenatal iron-deficient anaemia on brain development in a high-risk birth cohort
Nigeria 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tom  Ngabirano Denis
ID: UNCST-2020-R014491
 Effect of Enhanced Neonatal Jaundice Education on Knowledge, Early Detection and Care Seeking by Postnatal Mothers at Jinja Regional Referral Hospital
REFNo: HS1479ES

Objectives General objective To improve mothers’ knowledge of neonatal jaundice for early detection, proper care and prevention of severe neonatal jaundice. Specific objectives 1. To assess the level of mothers’ knowledge about neonatal jaundice at JRRH. 2. To implement an enhanced neonatal jaundice education package for postnatal mothers at JRRH. 3. To assess the effect of an enhanced neonatal jaundice education package on the level of knowledge, early detection and care seeking by postnatal mothers at JRRH.
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lukia Namaganda Hamid
ID:
Malnutrition as a probable predictor of mortality in cerebral palsy (CP), and the effect of positive deviance and parent facilitator training strategies to malnutrition and caregiving among children and adolescents with CP in the Iganga, Mayuge and Bugweri rural districts of eastern Uganda
REFNo: HS1427ES

Specific Objectives:
1. To assess mortality and whether malnutrition is one of the predictors among a population based sample of children and adolescents with cerebral palsy the Iganga Mayuge-Health and Demographic Surveillance Site (IM-HDSS), Uganda
2. To assess the difference in the change in nutritional status in 2015 and 2019 among children with CP compared to their age and sex matched controls without CP at the IM-HDSS, Uganda.
3. To explore positive and negative nutrition practices among caregivers of well-nourished and under-nourished children with cerebral palsy respectively at the IM-HDSS, Uganda.
4. To determine the difference in the effectiveness of the positive deviance strategy and parent facilitator trainings on CP child and adolescent malnutrition and caregiving within the Iganga, Mayuge and Bugweri districts, Uganda.

 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Degree Award
Scholastic Ashaba
ID: UNCST-2023-R007613
 Self-management among adolescents living with HIV in Uganda
REFNo: HS1697ES

Aim 3: Assess feasibility, acceptability, and preliminary effects of the self-management intervention on HIV outcomes for ALHIV transitioning to adult HIV care,Aim 2: Develop a self-management intervention that will enable ALHIV to successfully transition to adult HIV care,Aim 1: Use qualitative research to elaborate a conceptual model of the barriers faced by ALHIV transitioning to adult HIV care in Uganda,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Evaluation of a new stool-based qPCR for TB diagnosis in children and people living with HIV: a multicentre study in Eswatini, Mozambique and Uganda
REFNo: HS1615ES

To create a biorepository of well characterized pediatric samples at each of the study sites to support the future development and evaluation of novel biomarker research. ,To evaluate the quantitative stool qPCR platform as a tool to monitor treatment response in children and PLHIV,To compare the diagnostic performance of the stool qPCR platform to individual sputum and stool Xpert Ultra, urine LAM, sputum smear, sputum (MGIT) culture results against a clinical diagnosis and bacteriological reference standard,To evaluate the diagnostic accuracy of the stool Mtb qPCR tool compared to a composite reference standard (sputum and stool Xpert Ultra, sputum culture and urine TB-LAM) and clinical diagnosis. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lillian Wambuzi Ogwang
ID: UNCST-2021-R013189
 Seroprevalence of SARS-CoV-2 based on antibody testing among HIV infected mothers and their children in the PROMOTE Cohort at the MU-JHU Research Collaboration: July 2020 through June 2021 SUBSTUDY Version 2.0 Dated 16 Jun 2021
REFNo: HS1658ES

1. To determine the seroprevalence of COVID-19 IgG antibody among PROMOTE women living with HIV on antiretroviral therapy, and their HIV exposed children enrolled in PROMOTE; based on Roche ELISA antibody testing of plasma samples collected July 2020 to Jun 2021• To determine the association of COVID-19 exposure and PROMOTE participant characteristics such as age, CD4 count, BMI, maternal ARV therapy, pregnancy, Breast feeding, maternal Viral load, hospitalization in the past year with SARS-CoV-2 antibody positivity, comorbidity diagnosis (e.g. hypertension, obesity, asthma, TB, pulmonary, cardiac, renal disease, sickle cell disease).

3• To use PROMOTE data to determine maternal and pregnancy outcomes among PROMOTE women who were found to have had COVID-19 infection during pregnancy based on antibody testing during the period July 2020 - June 2021.

Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of the performance of the Salmonella Biolineâ„¢ typhi IgG/IgM Fast test in a near-patient testing environment, including evaluation of usability
REFNo: HS1700ES

To evaluate the usability of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in the near-patient environment using a questionnaire based survey. ,To establish the performance of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in a near-patient setting compared to the performance in a professional lab (i.e. Central Public Health Laboratory) using venous whole blood samples. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Non-degree Award
Martin Ariapa
ID: UNCST-2021-R013296
 Play and Learning in Children’s Eyes
REFNo: SS1022ES

To develop the Children’s Experiences of LtP Protocol (CELP) with its corresponding modules and items, intended for use by a coach or instructional support staff, by soliciting direct insights from children about their LtP experiences. To develop the Formative Observation and Reflection Assessment (FORA) with its corresponding modules and items, intended for use by ECD and primary education teachers as they implement a LtP practice in the classroom. To develop and validate a set of formative tools designed to help teachers in low-and middle-income countries assess and improve their practice in Learning through Play (LtP), through a deeper understanding of how children experience LtP in their classrooms,
 Uganda 2021-09-29 2024-09-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
herbert  Itabangi Itabangi
ID:
Metabolic and Molecular ecological evolution of opportunistic Pulmonary fungal co-infections (MeMoF project)
REFNo: HS1233ES

1. To determine the burden and aetiological profiles of fungal-co-infections among patients with chronic pulmonary disease suspected for Tuberculosis
2. To establish and characterise microbial communities associated with chronic pulmonary disease.
3. To characterise potential interaction relationships established between fungal and bacterial communities.

Uganda 2021-09-27 2024-09-27 Medical and Health Sciences Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Utilization of ART and TB treatment during the COVID-19 pandemic: A case of Kampala District
REFNo: HS1471ES

To determine the level of ART and TB treatment utilization among patients during the COVID-19 pandemics in Kampala district
To determine the factors associated with ART and TB treatment utilization among patients during the COVID-19 pandemic in Kampala district
To estimate the incidence rate of loss to follow-up among patients during the COVID-19 pandemics in Kampala district

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Kiondo
ID:
RISK FACTORS OF GENETIC CONSTITUTION, AND PREDICTORS PERSISTENT DISEASE IN WOMEN WITH MOLAR PREGNANCY ADMITTED AT MULAGO HOSPITAL, KAMPALA, UGANDA: A CASE-CONTROL STUDY
REFNo: HS1442ES

1. To determine the social, medical and obstetric risk factors of HM in women admitted at Mulago hospital, Kampala, Uganda.
2. To outline the outcomes of HM in women admitted in Mulago hospital, Kampala, Uganda.
3. To describe the genetic constitution of HM in women admitted at Mulago hospital, Kampala, Uganda.
4. To determine the predictors of persistent disease in women with HM admitted at Mulago hospital.

 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FIONA ASIIMWE
ID:
DIAGNOSTIC ACCURACY OF ULTRASOUND AND ADVERSE NEONATAL OUTCOMES AMONG WOMEN WITH A DIAGNOSIS OF NUCHAL CORD DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1531ES

General Objective
To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord and to compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord among women delivering at Mbarara Regional Referral Hospital.

Specific Objectives
1.To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord among women delivering at Mbarara Regional Referral Hospital.

2.To compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord delivering at Mbarara Regional Referral Hospital.

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Lawrence Mugisha
ID:
Evaluation of Wastewater-Based Epidemiology (WBE) tool for surveillance of COVID-19 in selected wastewater treatment plants and channels in Kampala-Entebbe Area, Uganda
REFNo: HS1725ES

Overall Objective: To provide COVID-19 surveillance data for a wider population based on wastewater monitoring as an early warning tool to inform outbreak response strategies
Specific Objective
1. To detect and characterize the SARS-CoV-2 virus in wastewater from wastewater treatment plants, channels and septic tanks of hospitals in Kampala and Entebbe
2. To evaluate and standardise the molecular detection methods for WBE


 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 COMPARISON OF PERFORMANCE OF CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA TEST DEVICE/ TEST REF: ISY-U402 AND CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA RAPID TEST STRIP) REF: ISY-U401 USING SD BIOLINE VERSION 3.0 AS A REFERENCE
REFNo: HS1643ES

The objective of this evaluation is to demonstrate the equivalence of capillary (fingerprick) whole blood and venous whole blood on the Syphilis Ultra test device/ Test strip (Whole Blood/Serum/ Plasma) and strip.
2.4 Exploratory Objectives
• To determine the diagnostic accuracy of the Syphilis Ultra test device/ Test (Whole Blood/Serum/ Plasma) and strip.

 Uganda 2021-09-23 2024-09-23 Medical and Health Sciences Clinical Trial Non-degree Award
Christopher Dolan Gerald
ID:
Improving access and retention in inclusive education for refugee children with disabilities
REFNo: SS937ES

I.To explore stakeholder’s understanding of the processes, challenges and opportunities for refugee children in accessing and progressing in inclusive education
II.To establish the current capacity of the education system to deliver safe and inclusive quality education for refugee children with special needs and disabilities
III.To describe the extent to which RCSN and their caretakers access timely and appropriate support to improve their physical, psychological and social functionality
IV.To establish the extent to which Key stakeholders effectively champion social accountability and implementation of policies and commitments on inclusive education
V.To examine the daily needs of RCWD and their carers

UK 2021-09-23 2024-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robens Mutatina
ID: UNCST-2021-R013633
 Psychosocial challenges and Coping Strategies among Caregivers of Children with Cerebral Palsy in South Western Uganda
REFNo: SS762ES

To determine the psychosocial challenges faced by caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

To describe the coping strategies of caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

 Uganda 2021-09-22 2024-09-22 Social Science and Humanities Non-degree Award
Samuel Biraro
ID:
Assessing the impact of COVID-19 on routine immunization demand and uptake, and understanding COVID-19 attitudes and perceptions in Uganda
REFNo: HS1679ES

1. Identify the range of factors affecting routine immunization uptake during the COVID-19 pandemic in order to inform key areas for mitigation intervention; and
2. Generate timely data on the range of factors that may influence demand and uptake of the COVID-19 vaccines among HCW and the public to identify strategies to promote optimal uptake of the COVID-19 vaccines.


Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary  Nanteza Bridget
ID:
ASSESSING A UGANDAN COMMUNITY FOR ACCEPTABILITY, SHORT- AND LONG-TERM SIDE EFFECTS OF COVID-19 VACCINE UPTAKE AND THE COLLECTION OF RELEVANT BIOLOGICAL SPECIMENS TO SUPPORT IMMUNOLOGICAL, HOST, AND VIROLOGICAL STUDIES ON COVID-19 VACCINE.
REFNo: HS1660ES

STUDY GOAL AND OBJECTIVES
The overall objective of this study is to assess acceptability, document short and long-term side effects, characterize break-through viruses that are linked to COVID-19 vaccination, and collect specimens for studies aimed at understanding host, viral and immunological factors associated with COVID-19 vaccine.
Specific objectives:
1. To assess the community knowledge, attitudes and perceptions (KAP) towards COVID-19 vaccines.
2. To describe the short and long-term side effects of COVID-19 vaccine provided at the UVRI clinic
Blood specimens will be collected for the following immunological and virological studies below:
3. To describe the sensitivity of COV ID-19 breakthrough viruses to prior and co-existing anti-SARS-COV-2 antibody and cellular immune responses after immunization with or without prior history of COVID-19 infection; and to also isolate SARS-CoV-2 Spike-specific human monoclonal antibodies in volunteers with strong neutralization responses.
4. To describe the correlation between pre-COVID-19 vaccination immune status, and outcome of vaccine induced immunity in newly vaccinated persons.
5. To describe COVID 19 immune responses in unvaccinated and already vaccinated persons before and after incident infections
6. To describe break-through viruses following COVID-19 immunization among the vaccinated persons

7. To describe host genetic factors that could be relevant for immune protection and disease outcome

Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Transitioning children to Optimal Regimens of Paediatric Dolutegravir (TORPEDO) in Uganda
REFNo: HS1596ES

the primary objective for the study is to assess patients’/ caregivers’ preference for a paediatric DTG regimen over their previous regimen, when transitioned from another regimen.

 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jihane Farhat Ben
ID:
Evaluation of two strategies part of the Differentiated Services Delivery Models (DSDM) in Fishermen’s landing sites at Lakes George and Edward, Western Uganda.
REFNo: HS1574ES

The main objective of the study is to describe acceptability and outcomes (VL suppression and
retention) relevance of MSF Landing site activities for the target populations to reorient
activities and document best practices.
The specific objectives are:
- To measure the proportion of eligible patients who enrol in CCLADs and FTR
- To compare characteristics of patients choosing CCLAD with those choosing FTR
- To measure the retention in care in CCLADS and in FTR at 6 and 12 months
- To measure the viral suppression for patients enrolled in CCLADS and in FTR for at least 1 year
- To describe acceptability and relevance of DSDM, peer zonal leaders, peers at the health facilities, VIP clinic days, OJT/CMEs for health workers and the information points.

France 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
IVAN IBANDA
ID:
Diagnostic and Treatment Delay of Tuberculosis: An In-depth Analysis of the Health-Seeking Behavior of Patients and the Health System Response in Kampala District
REFNo: HS1654ES

To determine the patient and system related factors that contribute to both diagnosis and treatment delays in Kampala District,To determine the proportion of patients that have a treatment delay for tuberculosis in Kampala District.,To determine the proportion of patients with tuberculosis diagnostic delay in Kampala District.,To evaluate the extent of diagnostic and treatment initiation delays of TB patients, identify the major contributors to such delays (patient or system), and study their various determinants.,
 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Goylette Chami
ID: UNCST-2023-R006262
 SchistoTrack: Determinants of schistosomiasis infection and morbidity as part of the Oxford-Uganda Collaboration on Schistosomiasis
REFNo: HS1664ES

Determine whether infection indicators are informative for measuring morbidity risks
associated with schistosomiasis;
2. Prioritize the most common morbidities associated with schistosomiasis, by age, that
require treatment and further research;
3. Understand the relative importance of environmental factors versus current infections for
schistosomiasis- associated morbidities.
4. Assess the feasibility of large-scale tracking of individuals with wearable GPS;
5. Determine whether spatial indicators from wearable devices can better predict individual
infection risk when compared to conventional approaches such as household surveys;
and
6. Develop methods to classify water contact sites based on individual usage and
contamination to understand whether there are focal points for transmission or super
spreaders.
USA 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Development and implementation of a patient-centred peer support intervention to promote the detection, reporting and management of adverse drug reactions among people living with HIV in Uganda
REFNo: HS1206ES

To estimate the effectiveness of the peer support intervention on the rate of ADR-reporting by PLHIV receiving DTG and/or IPT in Uganda,To describe the patterns of ADR-reporting (number, rate, time to reporting, seriousness) by PLHIV receiving DTG and/or IPT in whom the peer support intervention is implemented in Uganda,To determine the barriers and facilitators to implementation of the peer support intervention to promote ADR detection, reporting and management among PLHIV on DTG and/or IPT in Uganda,To develop an innovative peer support intervention for promoting the detection, reporting and management of ADRs in PLHIV receiving DTG and/or IPT in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
 Community Engagement and Schistosomiasis Prevention: A Sociological Analysis of the Citizen Science Model among Selected Communities of Western Uganda
REFNo: SS836ES

Purpose of the study
The purpose of the study is to examine the effectiveness of the Citizen Science model in community engagement to the prevention of schistosomiasis among selected communities of western Uganda. To do this, the study will determine the socio-cultural barriers to the uptake of preventive measures to guide in the development of health education initiatives that can be executed by the Citizen Scientists to help change the behaviour of the community for the prevention of schistosomiasis.

Objectives of the study
This shall be guided by the following research objectives:
1. To determine the level of knowledge, attitude, and practice regarding schistosomiasis among communities of Western Uganda;
2. To explore the health-seeking practices, attitudes, and behaviour associated with schistosomiasis prevention among communities of Western Uganda
3. To understand the lived experiences and perceptions of schistosomiasis by communities of Western Uganda to determine how citizen scientists can be useful in shaping community perspectives
4. To develop and implement contextualized communication strategies for schistosomiasis prevention based on the outcome of the objectives above with help of the citizen scientists
5. To assess the role of the citizen science model of community engagement in the prevention of schistosomiasis among communities of western Uganda

 Uganda 2021-09-21 2024-09-21 Social Science and Humanities Non-Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Rheumatic Heart Disease Community Streptococcal Treatment Program “RESET”
REFNo: HS1580ES

To improve the algorithm of the Strepic® device for Group A Strep Pharyngitis detection and then to test the performance as compared to microbiological culture (gold standard) and clinical decision rule.,To increase health seeking behavior for sore throat through a multifaceted community awareness campaign.,To improve guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based primary prevention.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ELIZABETH NALINTYA
ID: UNCST-2021-R012882
 Long title: A community-based Phase III, cluster randomized trial of point-of-care CD4 testing and enhanced screening and prophylaxis in advanced HIV disease Short title: An enhanced package of care to reduce mortality in advanced HIV disease
REFNo: HS1605ES

Primary Objectives:
1. To assess 24-week survival with retention in care in persons with advanced HIV disease (CD4<200 cells/µL) with point-of-care CD4 testing compared to standard flow cytometry
2. To assess 24-week survival with retention in care with an enhanced diagnostic OI screening and prophylaxis strategy compared to standard WHO package of care in persons with advanced HIV disease
Secondary Objectives:
1. To determine incidence of OIs
2. To measure adverse events with enhanced prophylaxis regimens
3. To assess tolerability and adherence of enhanced prophylaxis regimens
4. To determine incidence and cause of hospitalization for persons with advanced HIV disease
5. To determine cause of death for persons with advanced HIV disease
6. To determine HIV outcomes of viral suppression in persons with advanced HIV disease.
7. Measure cost, cost-effectiveness, and budgetary impact of the CD4 testing strategies, and OI screening and prophylaxis strategies.

 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Clinical Trial Non-degree Award
Graham Birch John
ID:
Title of research project: Oxidative shielding and the inter-generational costs of reproduction in male wild banded mongooses
REFNo: NS164ES

(1) To understand transgenerational influences on health and reproductive success in
wild mammals.
(2) To investigate the impact of paternal health on the development and reproductive
success of offspring, using banded mongooses as a model system.
 UK 2021-09-20 2024-09-20 Natural Sciences Degree Award
Fabian Mwosi
ID:
RETIREMENT PLANNING AND SOCIO-ECONOMIC STATUS OF CIVIL SERVANTS IN BUSOGA SUB-REGION, UGANDA.
REFNo: SS843ES

i. Investigate the relationship between saving culture and socio-economic status of retired civil servants in Busoga sub-region, Uganda
ii. Examine the relationship between financial planning and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iii. Assess the relationship between lifestyle and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iv. Explore the moderating effect of demographic factors on the relationship between retirement planning and socio-economic status in Busoga sub-region, Uganda
 Uganda 2021-09-20 2024-09-20 Social Science and Humanities Non-Clinical Trial Degree Award
Asenath Kwagalakwe
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS252ES

Investigating the physics of strain accommodation in the magma-poor Albertine-Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Hillary Mwongyera
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS264ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Determining the Effectiveness of Dispensing Messages (DEDIM) on Adherence and Viral Suppression among Children with an Unsuppressed Viral Load in Uganda
REFNo: HS1544ES

General Objective
To determine the effectiveness and implementation of dispensing messages on adherence and viral suppression among children with an unsuppressed viral load in Uganda

Specific objectives
1. To determine the facilitators and barriers to the delivery of dispensing messages to caregivers of children (< 15 years) living with HIV with an unsuppressed viral load in Uganda to inform the implementation strategy.
2. To assess the effectiveness of dispensing messages on outcomes of adherence and viral load suppression among children (<15 years) living with HIV with non-suppressed viral loads in Uganda.
3. To identify processes and contextual factors that explain the uptake, reach, and fidelity of delivery of ART dispensing messages to caregivers of children (< 15 years) living with HIV with unsuppressed viral load in Uganda

 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 The development and evaluation of a mobile phone-based intervention to facilitate continuity of care, symptom monitoring and self-management in palliative care patients in Uganda
REFNo: HS1600ES

vi. To develop best practices for patient-public engagement to empower cancer patients to support research in palliative care at different stages,v. To identify mechanisms of action for the intervention in supporting palliative care patients and their families ,iv. To determine uptake, patterns of clinical palliative care practice and factors influencing engagement with the mobile application ,iii. To deliver the novel intervention to two cohorts of palliative care patients , ii. To determine optimal implementation within routine palliative care practice at Yumbe Regional referral hospital palliative care unit and New Life Hospice ,i. To develop and evaluate a mobile phone-based (mpalliative) intervention to collect outcomes data and COVID-19, TB and hepatitis B symptoms from palliative care patients alongside developing a web-based application to communicate data to palliative care teams and facilitate continuity of care and self-management in palliative care patients in Uganda ,
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Uganda TB Care Cascade
REFNo: HS1718ES

1. To evaluate the accuracy of DHIS2 TB surveillance data using quantitative and mixed-methods approaches. 1a. To compare the accuracy of TB quality indicators measured with aggregate data compared to those measured with individual-level data. 1b. To explore discrepancies in the DHIS2 data using qualitative interviews.
2. To use routine surveillance data to describe the quality of TB care in Uganda.
3. To measure the impact of Xpert MTB/RIF on TB indicators in Uganda.
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 THRiVE Research Enrichment: Community and Public Engagement for Enhanced Impact
REFNo: HS1586ES

1. To enable doctoral trainees to work with young people in schools who will identify their preferred ways for engagement with THRiVE research.
2. To co-create and co-design at least one engagement project at each school led by student champions in collaboration with doctoral trainees and implemented based on one or more ways identified in objective 1 above.
3. To co-design and implement at least one student-centred drama skit and/or games for engagement of students with THRiVE doctoral trainees’ research, utilizing findings from objective one.
4. To publicize the public engagement in research work to stakeholders as a way of stimulating engagement of young people and doctoral trainees in PER.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane  Namusisi
ID: UNCST-2021-R013619
 seizure control and associated factors among children with epilepsy at Mbarara Regional Referral Hospital
REFNo: HS1657ES

MAIN OBJECTIVE
To determine the seizure control status and describe its associated factors among children attending the Epilepsy Clinic at MRRH for at least six months.
SPECIFIC OBJECTIVES;
1. To identify the seizure types among children under care for at least six months at the Epilepsy Clinic, MRRH.
2.To determine the proportion of children with epilepsy with poor seizure control under care for at least six months at the MRRH Epilepsy clinic.
3.To identify the factors associated with poor seizure control among children under care for at least six months at the MRRH Epilepsy clinic.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Human-Centred Design and Communities of Practice to Improve Delivery of Home based Tuberculosis Contact Investigation in Uganda
REFNo: HS1720ES

General Objective: The study aims to assess the effectiveness of an enhanced intervention strategy for implementing TB contact investigation relative to usual care. Specific Objectives: 1.To compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced intervention strategy vs. the usual care strategy in a stepped-wedge, cluster-randomized implementation trial. 2.To identify implementation processes and contextual factors that influence the effectiveness of the intervention strategy for TB contact investigation. 3.To compare the costs and epidemiological impact of the intervention and usual care strategies for TB contact investigation.
Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 SeqCOVID consortium: EAC participation – Sequencing of COVID-19 isolates from the East African Region
REFNo: HS1592ES

Epidemiological Analysis of current COVID outbreak,Capacity Building in East Africa and setting up of Prospective COVID Surveillance Platform,Diagnostic and Vaccine Development for East African COVID variants: - describe East African COVID variants and predict immunogenic epitopes and drug targets in silico, The aim of the present project is for the East African region to actively contribute data for COVID-19 drug and vaccine development, to equip the region for the time after a vaccine and drugs were developed and also to prepare for future outbreaks.,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Nalumu
ID:
ASSESSING FACTORS ASSOCIATED WITH NEONATAL DEATHS IN BUSIA DISTRICT; CASE STUDY OF MASAFU, DABANI AND BUSIA HEALTH FACILITIES
REFNo: HS1711ES

1. To assess factors associated with neonatal deaths in Busia district such that we make recommendations, according to the findings, on what measures to adopted in order to reduce neonatal mortality in the district and the country,4. To examine health facility factors associated with neonatal deaths in Busia district,3. To establish neonatal related factors associated neonatal deaths in Busia district ,2. To determine maternal factors associated with neonatal deaths in Busia district ,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Janet SEELEY
ID:
Multimorbidity in Africa - Increasing Understanding of the Health Workers’ Experiences and Epidemiology (MAfricaEE)
REFNo: SS998ES

Explore the healthcare professionals' (HCPs) experiences of treating and managing patients with multi-morbidity in Uganda and what health workers see as the main barriers to optimal care provision. How do health care professiönals view the potential impacts of COVID-19 on care for patients with multi-morbidity?
 UK 2021-09-13 2024-09-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick  Oporia
ID:
Improving use of seaworthy life jackets among boaters on Lake Albert, Uganda. A cluster randomized trial
REFNo: SS992ES

1. To estimate the prevalence of life jacket use among boaters on Lake Albert.

2. To identify the determinants of life jacket use among boaters on Lake Albert

3. To determine the seaworthiness of life jackets used by boaters on Lake Albert

4. To design a behavior change intervention aimed at improving use of seaworthy life jackets among boaters on Lake Albert

5. To pilot and evaluate the effectiveness of a behavior change intervention on improving use of seaworthy life jackets among boaters on Lake Albert

 Uganda 2021-09-10 2024-09-10 Social Science and Humanities Degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda
REFNo: SS935ES

This project asks whether business relocation within the city could increase profits for microfirms in Kampala, Uganda, and if so, then what frictions (constraints) restrict a firm’s ability to relocate without intervention. Ultimately, this project plans to use a multi-arm randomized experiment to accomplish 3 aims: to detect appetite for business relocation, whether relocation increases profits, and which of the tested frictions might constrain location choice. In the first phase of the research, the project will survey microfirms in Kampala to understand their current locations, how profits vary by location across the city, what aspirations the business owners have with respect to future business growth, and what challenges they perceive to accomplishing business growth.
USA 2021-09-10 2024-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
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