Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Khamisi Musanje
ID: UNCST-2021-R012863
Acceptability, Feasibility and Effectiveness of a Mindfulness based Intervention to Promote Adherence to Antiretroviral Therapy among Adolescents in Kampala.
REFNo: HS1656ES

1. To adapt and explore acceptability of ACT-DNA-v among users (ALWHA) and providers (HCPs).
2. To measure feasibility of the adapted ACT-DNA-v for use with ALWHA.
3. To examine the impact of ACT-DNA-v on reducing proximal psychosocial barriers to medication adherence (depression, anxiety and stigma) among ALWHA.
4. To measure effectiveness of a mindfulness based intervention (ACT-DNA-v) on self-reported adherence among ALWHA in Kampala, and ascertain its impact on viral load reduction via analysis of data from medical records

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
SEVERE PNEUMONIA IN CHILDREN: THE ABILITY OF BODY COMPOSITION TO PREDICT SURVIVAL, AND THE EFFECT OF NUTRITIONAL SUPPLEMENTATION ON OUTCOMES
REFNo: HS1719ES

4. To determine the effect of a nutritional intervention (RUTF) on clinical outcomes (post discharge mortality, re-admission, and occurrence of severe acute malnutrition) of children hospitalized for severe pneumonia.,3. To determine the effect of a nutritional intervention (RUTF) on fat and muscle mass in children hospitalised for severe pneumonia.,2. To compare the ability of various muscle and fat mass indices to predict survival in children hospitalised for severe pneumonia.,1. To describe the role of nutritional status on outcomes following hospitalization for severe pneumonia among children.,To describe the relationship between muscle and fat mass and survival, and determine the role of nutritional supplementation on fat and muscle mass, and on treatment outcomes of children hospitalized for severe pneumonia,
Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
A Public Health Approach to Cervical Cancer Prevention in Uganda
REFNo: HS1727ES

Aim 1. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based cervical cancer screening program.

Aim 2. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based HPV vaccination program.

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Adakun
ID:
Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES

Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives

1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology


2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sandra Lamwaka
ID:
TOWARDS A NEWS INDUSTRY FRAMEWORK FOR TACKLING THE VICE OF BROWN ENVELOPE JOURNALISM: PERCEPTIONS OF JOURNALISTS AND PUBLIC RELATIONS PRACTITIONERS IN UGANDA
REFNo: SS1014ES

1. To examine journalists and PR practitioners’ perception of the brown envelope. 2. To identify the various forms that BEJ takes in Uganda. 3. To find out journalists and PR practitioners' perceptions on why BEJ is prevalent and enduring in Uganda. 4. To find out journalists and PR practitioner's perspectives on the policies that the media industry can employ to address the practice of BEJ in Uganda.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
JANISCH Judith Judith
ID:
Ecological influences on Locomotor Performance in Free-Ranging Primates: a phylogenetic investigation
REFNo: NS299ES

- to investigate the evolution of arboreal locomotion in primates and discern which aspects of the arboreal environment most directly influence their locomotor performance.
- to describe kinematics of different primate species (Cercopithecus mitis, Cercopithecus ascanius, Cercopithecus lhoesti, Chlorocebus aethiops,
Lophocebus albigena, Papio anubis, Colobus guereza and Piliocolobus badius) in
their natural habitat and analyze the variation in a phylogenetic context.

Austria 2021-10-19 2024-10-19 Natural Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Exploration of the Virologic Characteristics of Recently Transmitted HIV-1 Viruses in Uganda and Kenya
REFNo: HS1635ES

1. To identify key unique molecular features of T/F virus strains and characterize them
2. To relate these unique genetic features to viral protein structures and in vitro virus phenotypes.
3. To determine the difference between HIV-1 co-receptor usage of the T/F virus variants and NT virus strains.
4. To determine particle infectivity of T/F virus strains in comparison to that of the NT virus strains.
5. To compare the resistance of T/F virus strains to the antiviral effects of type I interferons to that of the NT strains
6. To determine the sensitivity of T/F virus strains to broadly neutralizing antibodies in comparison to the non-transmitted virus strains.
Uganda 2021-10-15 2024-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noah Kalengo
ID:
LIVED EXPERIENCES OF UNCIRCUMCISED POKOT WOMEN IN AMUDAT DISTRICT
REFNo: SS1046ES

To explore the characteristics of uncircumcised Pokot women in Amudat District.

To explore the psychosocial experiences of uncircumcised Pokot women in Amudat District.

To analyze the protective factors/coping resources among the uncircumcised Pokot women that enable them to survive despite their experiences.

Uganda 2021-10-15 2024-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
Feasibility and acceptability of integrating PrEP and safer conception messaging into assisted partner notification
REFNo: HS1625ES

To examine the feasibility and acceptability of integrating gain-framed vs. loss-framed messages on PrEP and safer conception into the assisted partner notification (APN) program in Uganda
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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