Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Denis Byarugaba Karuhize
ID: UNCST-2023-R006496
 Severe acute respiratory infections (SARI) surveillance in hospitalized patients in Uganda
REFNo: HS4166ES

i) To better understand SARI etiology (influenza and other respiratory viruses), severity and risk factors among hospitalized patients with SARI from all age groups
ii) Contribute to Uganda’s and global response and management of SARI
iii) Contribute to international capabilities and collaboration to integrate clinical virological and genomic influenza and other respiratory pathogens surveillance data through the WHO Global Influenza Surveillance and Response System (GISRS) to support intervention and better SARI management and response including influenza vaccine selection, vaccine escape as well other respiratory virus vaccines
iv) Support international alert and response system for emerging strains of pandemic potential

 Uganda 2024-05-29 9:45:45 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Secondary use of Uganda Population-based HIV Impact Assessment (UPHIA) samples and associated data for micronutrient surveillance
REFNo: HS4333ES

2. Assess for associations between micronutrient status with HIV status and related indicators using 2020 - 2021 UPHIA metadata,1. Determine national and sub-national prevalence estimates for MND using 2020 - 2021 UPHIA samples,
 Uganda 2024-05-29 9:42:49 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sherifah Nabikande
ID: UNCST-2022-R009631
 Uptake of HIV prevention interventions among adolescent girls and young women in slum settings in Kampala district, Uganda
REFNo: HS4015ES

3) To explore the barriers and facilitators of condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,2) To determine the factors associated with condom use, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions among AGYW in slum settings in Kampala district, Uganda,1) To determine the proportion of AGYW who use condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions in slum settings in Kampala district, Uganda,To determine the uptake of condoms, HIV testing and Pre-exposure prophylaxis as HIV prevention interventions and factors associated among AGYW in slum settings in Kampala district, Uganda ,
 Uganda 2024-05-29 9:40:25 2027-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 A randomized, open-label, multicenter study to compare efficacy, safety and tolerability of KLU156 with Coartem® in the treatment of uncomplicated Plasmodium falciparum malaria in adults and children ≥ 5 kg body weight followed by an Extension phase with repeated KLU156 treatment.
REFNo: HS3732ES

This study aims to confirm the efficacy, safety and tolerability of KLU156, a fixed dose combination of ganaplacide (KAF156) and a solid dispersion formulation of lumefantrine (lumefantrine-SDF), when administered once daily for three days in adults and children ≥ 5 kg body weight and ≥ 2 months of age suffering from uncomplicated P.Falciparum malaria (with or without other plasmodium spp. co-infection). In the Extension phase, the safety, tolerability and efficacy of repeated treatment with KLU156 will be assessed for a maximum of two years in patients who did not experience early treatment failure(ETF), who did not experience any study treatment-related SAE (Serious Adverse Event) previously and who gave informed consent to participate in the Extension phase.
 Uganda 2024-05-29 9:37:35 2027-05-29 Medical and Health Sciences Clinical Trial Non-degree Award
Christine kisubi Esther
ID:
ENVIRONMENTAL JUSTICE IN UGANDA’S OIL AND GAS UPSTREAM SUB-SECTOR DECISION-MAKING
REFNo: SS2634ES

To critically examine the legal frameworks and their implementation concerning environmental justice and community participation in decision-making processes within Uganda\'s oil and gas upstream sub-sector.,
 Uganda 2024-05-27 9:01:35 2027-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
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