Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Irene  Nakatudde
ID:
Excessive weight gain and associated factors in HIV-infected adolescents on dolutegravir-based antiretroviral therapy in Kampala, Uganda
REFNo: HS1837ES

1. To determine the prevalence of excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.
2. To identify the factors associated with excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.

Uganda 2021-11-03 2024-11-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Secondary Research of MUWRP Sepsis Study Biospecimens: UNC 1 Evaluation of a Lateral Flow Immunoassay for Measuring Covid-19 Antibodies and 2 Related Inflammatory Biomarkers
REFNo: HS1821ES

The objective of the UNC study is to understand if the nonpowered lateral flow assay technology is as accurate as the powered GenScript SARS-CoV-2 surrogate virus neutralization test in detecting COVID-19 infection
Uganda 2021-11-02 2024-11-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Kisambu
ID:
Uganda Prisons Service Project Evaluation Protocol
REFNo: HS1307ES

Objectives of UPS Program Evaluation
i. To evaluate the targeted HTC models to improve earlier identification of HIV-positive and negative individuals, and linkage of people living with HIV (PLHIV) in prisons community and facility sites and linkage and promotion of HIV prevention among HIV-negative individuals
ii. To evaluate innovative approaches that increase adherence, ART retention, and viral load (VL) suppression among adult and pediatric HIV clients.
iii. To determine if there is improved identification of TB-infected individuals, effective scale up of comprehensive TB/HIV services at individual sites, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC-supported prison facilities
iv. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV-positive and syphilis-infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, VL suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV and syphilis and ensure documentation of 18 month final outcome status for all HEIs
v. To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at the facility level
vi. To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at the facility level.
vii. To determine the relationship between regional prison level performance reviews and human resource (HR) performance on facility performance including access, coverage, retention and loss to follow up.


Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
Isoniazid preventive and antiretroviral therapy-associated Pellagra: A case series of Reach Out Mbuya.
REFNo: HS1474ES

To describe the clinical manifestations of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra 2. To review the health outcomes of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra particularly as related to INH withdrawal
Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Ifeagwu
ID:
The perceptions and values of multisectoral stakeholders related to universal health coverage (UHC) in Uganda
REFNo: HS1478ES

General objective:
To explore the perceptions, understanding and importance of achieving universal health coverage (UHC) by key stakeholders in Uganda.


Specific objectives:
a. To establish and enumerate the perceived importance being given to UHC as well as key barriers and challenges to achieving UHC in Uganda by national, regional and international health policymakers.
b. To understand local healthcare workers’ awareness and perceptions of UHC and examine differences between the views of urban and rural healthcare workers.
c. To determine the urgency, need, perceived impact (against the Sustainable Development Goals) placed on UHC by stakeholders, including policymakers and healthcare workers.
d. To use generated evidence to develop a policy brief using case examples highlighting promising approaches to support multisectoral UHC collaboration.

Austria 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Theopista Fokukora
ID:
IMPROVING ACCESS AND USE OF EMERGENCY CONTRACEPTION AMONG ADOLESCENTS IN THE TOORO SUB-REGION OF UGANDA
REFNo: HS1829ES

1. To assess the prevalence of EC use among adolescents in Tooro Sub-region, Uganda
2. To investigate the individual factors associated with ECs use among adolescents in Tooro Sub-region, Uganda.
3. To investigate the community-based socio-economic and cultural factors associated with EC use among adolescents in Tooro Sub-region, Uganda.
4. To assess the health system and service provider factors associated with the provision of ECs to adolescents in Tooro Sub-region, Uganda.
5. To determine the effect of a reproductive health education intervention on knowledge, attitude, and practices of providers as well as utilization of EC among adolescents.

Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Bangirana
ID:
Developing the Uganda National Mental Health Response to Disasters
REFNo: SS995ES

To design a national mental health response for disasters,To evaluate the cost effectiveness of implementing the intervention,To identify enabling factors for implementing the intervention in the relevant government ministries (acceptability),To identify barriers to implementation of the intervention in the community (feasibility),a)To develop a psychosocial intervention for victims, their families and health care workers during disasters,
Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Acanit
ID:
Use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda
REFNo: SS948ES

To examine the use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda, with a view of suggesting a model to improve the use of those resources among engineering students.
Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Degree Award
Namulema Edith
ID:
Effectiveness of the ‘LeVe CPAP’ against the standard AIRVO CPAP among Covid-19 patients with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A Cross-Over Randomised Trial.
REFNo: HS1647ES

The main objective of the trial is to compare the clinical effectiveness of the LeVe CPAP device to the standard AIRVO CPAP in the delivery and maintaining continuous positive airway pressures among patients diagnosed with AHRF at Mengo Hospital Uganda.
Uganda 2021-10-28 2024-10-28 Medical and Health Sciences Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
Optimizing Performance of the Human Powered Nebulizer Prototype; Exploring stakeholder perceptions towards the human-powered nebulizer
REFNo: HS1433ES

We aim to explore the perceptions towards the human-powered nebulizer by the stakeholders (health care workers, village health teams and caregivers).
Uganda 2021-10-27 2024-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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