Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
|
BREATHER Plus: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir- based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub-Saharan Africa, Version 2.0, Dated 18-Mar-2020; ISRCTN #: 85058577
REFNo: HS1822ES
Major Objective: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub- Saharan Africa
Specific Objectives
To evaluate an innovative and contemporary ART strategy in HIV-infected adolescents to provide choice for young people facing life-long treatment. Output from this RCT will provide evidence on efficacy, safety and acceptability of a novel treatment approach in HIV-infected adolescents in sub-Saharan Africa
To evaluate the virological efficacy, safety, acceptability and Quality of Life of DTG-based Short-cycle Therapy with weekends off compared with Continuous Therapy with a DTG- based ART regimen
To optimize treatment for HIV-infected adolescents in sub-Saharan Africa
|
Uganda |
2021-11-15 |
2024-11-15 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
|
Mvuyo Sikhondze Maqhawe
ID:
|
DIABETIC FOOT ULCERS: SURGICAL CHARACTERISTICS, TREATMENT MODALITIES AND SHORT-TERM TREATMENT OUTCOMES AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1857ES
General Objective
To describe the surgical characteristics, treatment modalities and short-term treatment outcomes of diabetic foot ulcers at Mbarara Regional Referral Hospital.
Specific Objectives
1. To describe the surgical characteristics of diabetic foot ulcers observed at Mbarara Regional Referral Hospital.
2. To describe the treatment modalities of diabetic foot ulcers at Mbarara Regional Referral Hospital.
3. To document the short-term treatment outcomes of patients with diabetic foot ulcers at Mbarara Regional Referral Hospital.
|
Eswatini |
2021-11-15 |
2024-11-15 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
|
Sabine, Willemina, Johanna Luning
ID:
|
Gold Matters: Transformations to Sustainability in Artisanal and Small Scale Gold Mining in Uganda
REFNo: SS716ES
1. To consider whether a transformative approach toward sustainability can arise in Artisanal and Small Scale Gold Mining (ASGM).
2. To explore new notions of sustainability and transformations.
3. To contribute to a better understanding of the dynamic, heterogeneous reality of ASGM.
|
Netherlands |
2021-11-11 |
2024-11-11 |
Social Science and Humanities |
|
Degree Award |
|
Jessica Perkins M
ID: UNCST-2021-R013564
|
Perceptions of Social Norms and Personal Propensity to Engage in HIV Testing: A Mixed Methods Study and Intervention in Rural Uganda
REFNo: SS812ES
We propose a study to assess norms and perceptions about HIV prevention and related topics. This includes assessing village norms (i.e., the behaviours or attitudes of more than 50% of the adult population), perceived norms, how people form their perceptions, which social reference groups are the most meaningful, and the difference between actual norms and individuals’ perceptions of what most others do or believe. We will also examine whether perceptions are associated with personal behaviours and attitudes.
Project 1 Aim: To engage in secondary analysis of quantitative data about perceived social norms and actual population norms around HIV prevention behaviours and related topics across different social reference groups.
Aim 1: We will assess the prevalence of perceived and actual behavioural norms. We will do this both at the village-level and across various sociodemographic and health indicators. We will consider a behaviour the village norm if it is reported by more than 50% of adults.
Aim 2: Because the parent study includes nearly all adults living in Nyakabare Parish, we can compare the actual village norm (assessed in Aim 1) to perceptions of the village norm. The parent study asked participants about their perceptions of what most other adults in the village do or think.
Aim 3: Using the self-reported behaviours, attitudes, and norm perceptions, we will test whether individuals’ perceptions of what is normative is related to their personal attitudes and behaviours.
Project 2 Aim: To use qualitative research methods to understand the nuances of HopeNet participants’ perceptions about local norms and design valid survey questions that elicit perceived social norms about HIV testing within different reference groups.
Aim 1: Through in-depth interviews, scenarios related to HIV prevention attitudes and behaviours and perceived norms about salient social reference groups will be discussed.
Aim 2: Based on results from Aim 1, survey questions using different ways of assessing norms will be developed to assess perceived social norms around HIV-related prevention behaviours and attitudes among different reference groups.
Aim 3: Through cognitive interviews, the content validity of these survey questions to elicit perceptions of social norms about HIV-related attitudes and behaviours among specific social reference groups will improve.
|
USA |
2021-11-11 |
2024-11-11 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
SIMON EWASU -
ID:
|
EXPLORING THE INFLUENCE OF SCHOOL LEADERSHIP ON STUDENTS’ ACADEMIC PERFORMANCE: A COMPARATIVE STUDY OF TWO PRIMARY SCHOOLS’ IN OMODOI SUB-COUNTY-UGANDA
REFNo: SS980ES
1. To explore how school leadership influences learners’ academic performance in schools’?
2. What school leaders do to improve on the students’ academic performance in schools
3. To find out the teachers’ and students’ perceptions on the school leadership on students’ academic performance.
4. To find out the strategies school leaders employ to support their own teams to improve on the learner’s academic performance?
|
Uganda |
2021-11-11 |
2024-11-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Hannah Kibuuka
ID: UNCST-2020-R014355
|
Modular Wireless Patient Monitoring System (MWPMS) Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1687ES
At the FPRRH study site in Uganda, investigators will incorporate an assessment of the utility of a novel Modular Wireless Patient Monitoring System (MWPMS), supported by personalized data analytics, to provide a continuous, objective measure of physiological status in patients with sepsis. We aim to demonstrate correlation with manually collected vital signs. We also aim to identify specific features or combinations of features measured via MWPMS that predict 28-day mortality. This is a sub-study which will be incorporated in the main protocol observing sepsis patients hospitalized in Uganda
|
Uganda |
2021-11-11 |
2024-11-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Owenda Omulo Charles
ID:
|
The socioeconomic impact of floriculture industry on the livelihoods of communities hosting flower farms in Uganda
REFNo: SS1004ES
Main Objective
The main aim of this study is to examine the socio-economic impact of flower farm projects on the livelihoods of their host communities.
Specific Objectives
Specifically, the study will have the following objectives and associated research questions;
To find out how the financial reward (wages) has contributed in changing the livelihood of flower farm workers from the time they joined the flower farm.
To examine the extent by which flower farms have contributed to the improvement of the basic infrastructure and producer goods needed to support people’s livelihoods in their host communities.
To find out how the farms are prepared to overcome the challenges of environmental degradation and human abuse (as witnessed in workers’ exposure to hazardous agrochemicals in other countries) in order to improve people’s livelihoods.
|
Kenya |
2021-11-11 |
2024-11-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Christine Watera
ID:
|
Cyclical Acquired HIV Drug Resistance Surveillance: Focusing on Dolutegravir in Uganda
REFNo: HS1774ES
a) To estimate the prevalence of acquired drug resistance (ADR) among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
• Adolescents and Adults ≥ 15 years
• Children < 15 years old
b) To describe the patterns of ADR among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
c) To describe the prevalence and pattern of ADR among individuals receiving DTG with VL non-suppression by sub-population characteristics (e.g., sex, duration on antiretroviral therapy (ART), line of ART, pregnant and breast feeding, etc.):
d) To compare the proportion of individuals with HIVDR pre- and post-intensive adherence counselling (IAC)
|
Uganda |
2021-11-11 |
2024-11-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Edith Birungi Mwebaze
ID:
|
Decision Making Dynamics in the use of Female Sterilisation by Women Living with HIV in Uganda
REFNo: SS1044ES
To explore the personal factors that influence the agency to implement decisions regarding use of sterilisation by women living with HIV in Uganda, To describe the micro-level social contexts that influence the decisions of Women Living with HIV on the sue of female sterilisation by as a method of contraception, To assess the macro- level cultural contexts that influence the decisions of Women Living with HIV to use sterilisation.
|
Uganda |
2021-11-11 |
2024-11-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
|
Agata Staniewicz
ID: UNCST-2021-R012236
|
Interspecific competition for acoustic space in birds
REFNo: NS302ES
Determine whether and how various species of birds compete with each other and with other animals for acoustic space.
|
Poland |
2021-11-11 |
2024-11-11 |
Natural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
| View |
|
Sort By: |
|
|
|
| |
|