Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Neil Scolding
ID: UNCST-2021-R012864
The clinical neurology of chronic Nodding Syndrome: a proposal for a secondary usage of clinical data for research
REFNo: HS1848ES

To analyse and publish our previously-obtained clinical and neurological information on NS, gained from clinical encounters with NS suffers
UK 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bob Rich Mwecumi  Muhereza
ID:
DIGITAL MIGRATION AND COVERAGE OF DIGITAL TELEVISION SERVICES IN UGANDA
REFNo: SIR85ES

i. To establish the relationship between cost of digital infrastructure and coverage of digital TV services in Uganda.
ii. To establish the relationship between consumer awareness and coverage of digital TV services in Uganda.
iii. To assess the effect of subscription payments on coverage of digital TV services in Uganda.
iv. To investigate the effect of special interactive services on coverage of digital TV services in Uganda.

Uganda 2022-01-27 2025-01-27 Engineering and Technology Non-Clinical Trial Degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
International Prevalence Surveys of Helicobacter pylori in High and Low Risk Areas for Stomach Cancer Epidemiological iNvestigatIon of Gastric Malignancies – ENIGMA
REFNo: HS1891ES

Objectives of the research project: i. To estimate the age-specific prevalence of Helicobacter pylori infection as predictor of Gastric Cancer trends. ii. To investigate bacterial, host and environmental factors associated with differences between high and low Gastric Cancer risk areas. iii. To measure H. pylori antibiotic resistance to Metronidazole and Clarithromycin in the different geographic regions. iv. To further explore the association between H. pylori infection and child growth
UK 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda Ndidde
ID: UNCST-2020-R014331
Field Performance Evaluation of the Xpert® HIV-1 Viral Load assay for Viral Load (VL) monitoring in Uganda
REFNo: HS1977ES

To determine acceptability of the the Xpert® HIV-1 Viral Load assay by the study participants.,To determine changes in turn-around time and ease of clinic workflow integration,To determine the operational characteristics of the Xpert® HIV-1 Viral Load assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel ,To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the Xpert® HIV-1 Viral Load assay in comparison to a reference assay, Roche COBAS 8800 in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected. ,To evaluate the field performance of the Xpert® HIV-1 Viral Load assay in identifying virological failure (VF) in adults on ART. The performance will be compared to the reference assay, the Roche COBAS 8800 used at UNHLS. ,
Uganda 2022-01-27 2025-01-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Designing an intervention to increase HIV self-testing uptake and clinic linkage among men in Uganda: A Discrete Choice Experiment
REFNo: HS1061ES

Aim 1: To pilot test two HIVST Discrete Choice Experiments on 1) distribution strategies and 2) linkage strategies to assess how well participants understand the questionnaire and inform final design.

Aim 2: To conduct a DCE to determine men’s preferred HIVST distribution strategy to increase uptake. We will assess men’s preference for mode of HIVST distribution (e.g. pharmacy, drug shop, clinic, partner, friend), pre-test support, and post-test support.

Aim 3: To conduct a DCE to determine men’s preferred intervention to increase clinic linkage for HIV care and prevention after HIVST. We will assess the potential of financial incentives, screening for other diseases, fast-track services, and peer navigators to motivate men to link to care.
Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-degree Award
Samuel Meyerson
ID:
From the Kraals to the Markets: A Pastoral World Beyond the State in East Africa
REFNo: SS1045ES

1. To analyze the transnational networks that have connected Ateker communities in East Africa from the precolonial era to the present day. 2. To examine the historical relationships between Ateker communities and state structures in East African countries during the colonial and post-independence periods. 3. To use historical analysis to identify ways of fostering national integration and sustainable development in Karamoja.
Canada 2022-01-25 2025-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
FREDRICK MAKUMBI
ID:
Assessment of the Scale, Reach, Quality, and Cost of Service Delivery High Impact Practices in Family Planning in Uganda
REFNo: HS2005ES

To estimate the costs of implementing and sustaining service delivery, and identify the cost drivers, and efficiencies for selected HIPs in Uganda ,To assess the quality of services for selected service delivery HIPs, including policy-level intention and readiness of services to offer the HIP in Uganda ,To measure the current reach of selected service delivery HIPs to sub-populations by age, urban/rural location of service delivery points, and, if applicable, new FP users in Uganda,To measure the current horizontal and vertical scale of implementation of 3 service delivery HIPs in Uganda,The goal of this assessment is to develop and apply a replicable approach that measures the scale, reach, quality, and cost of HIPs, information which will help Uganda and other countries to critically analyze and maximize their investments in comprehensive FP strategies. ,
Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
Safety and Efficacy of COVIDEX™ Therapy in Management of adult Covid-19 Patients in Uganda: A randomized double-blind placebo controlled adaptive phase 2 B clinical trial.
REFNo: HS2041ES

3. To determine the plasma concentration of berberine in COVID-19 patients receiving COVIDEX. ,2. To determine the efficacy of COVIDEXTm for treatment of COVID-19 among adults in Uganda.,To determine the efficacy of COVIDEXTm for treatment of COVID-19 among adults in Uganda.,To validate the safety and determine the efficacy of COVIDEXTm therapy for treatment of COVID-19 in adult Ugandans. ,
Uganda 2022-01-25 2025-01-25 Medical and Health Sciences Clinical Trial Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
Evaluating the implementation of assisted partner notification for HIV in refugee settlements in West Nile Uganda: An implementation Science approach
REFNo: HS1970ES

AIM 2.To explore barriers and facilitators to APN for HIV in refugee settlements in West Nile using qualitative methods to evaluate each stage of RE-AIM, guided by the Consolidated Framework for Implementation Research (CFIR) domains. ,AIM 1. To assess the reach, effectiveness, adoption, implementation, and maintenance of APN for HIV in refugee settlements in West Nile utilizing the RE-AIM framework. ,
Uganda 2022-01-24 2025-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Nanfuka Kalule
ID:
Resilience during and After quarantine: A qualitative study of people affected by Covid-19 in Uganda
REFNo: SS1047ES

1. To examine the socio-economic constraints faced during and after quarantine
2. To examine the psychological constraints faced during and after quarantine
3. To examine the protective factors that facilitated the successful management of the socio-economic and psychological risks faced during and after quarantine.

Uganda 2022-01-21 2025-01-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
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