Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
John Paul Byagamy Byagamy
ID:
Water physico-chemical effect on seasonal snail vector distribution and human infection with Schistosomiasis in selected agricultural areas in Lango sub region, Northern Uganda
REFNo: HS2571ES

Specific Objectives
1.To characterize the ecological and physicochemical properties of snail vectors breeding habitats in the districts of Lira and Kole.
2.To determine the seasonal distribution and abundance of snail vectors in Lira and Kole.
3.To determine the snail species and their infection rates with schistosomes in selected areas in Lira and Kole districts.
4.To determine the human infection rates with schistosomes among populations in selected agricultural areas in Lango sub region, northern Uganda.

Uganda 2022-11-28 12:17:20 2025-11-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Yiga
ID:
Fresh fruit and vegetable consumption in Uganda; barriers, facilitators and current consumption practices
REFNo: HS2552ES

1. To understand consumer motives and barriers to / not to consume (specific) fruits and vegetables
2. To know the proportion of target market consumers who demonstrate a preference to deliberately avoid unsafe sprayed FFV products in favour of safe FFV
3. To know what consumers do with the FFV they purchase and whether it affects their nutritional value and food safety
4. To know how processing of FFV products respond to consumer needs
5. To get insights on strategies that show potential to drive the consumption of FFV in Uganda

Uganda 2022-11-28 11:57:58 2025-11-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jasper Ocen
ID:
Gendered participation in intra-household decision making for Agricultural credit in Acholi sub-region
REFNo: A241ES

To determine credit conditions affecting gendered participation in intra-household decisions for Agricultural credit,To assess socio-economic factors determining differences in gendered participation in intra-household decisions for Agricultural credit,. To establish the level of power relations in intra-household decisions for Agricultural credit., To assess how intra-household gender relations influence credit uptake by farming households ,
Uganda 2022-11-28 11:46:45 2025-11-28 Agricultural Sciences Non-Clinical Trial Degree Award
Nicholas Bbosa
ID:
Viral Pathogen Surveillance and Discovery in Uganda
REFNo: HS2543ES

1. Surveillance: Determine the genetic diversity and prevalence of HIV, HBV, HDV, HCV and SARS-CoV-2 molecular variants circulating in Uganda and adjacent African countries.
2. Discovery: Identify novel pathogens from patients and at autopsy with illnesses of unknown etiology and characterize any viral genomic sequences detected in such patients and autopsies.
3. Assay prototyping: Evaluate the performance of blood screening and other diagnostic assays in development.

Uganda 2022-11-28 11:43:26 2025-11-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
An evaluation protocol by Baylor-Uganda titled: Leveraging on the Orphan and Vulnerable Children (OVC) platform to Improve TB case finding, TB Preventive therapy and TB treatment outcomes under ACE-FORT Project
REFNo: HS2534ES

1) Conduct a baseline TB/HIV performance indicator assessment among OVC supported under the ACE-Fort project.
2) Compare TB case finding, prevention and treatment outcomes before and after implementing accelerated TB-OVC integrated services,
3) Describe geographical hotspots with high number of OVC with TB under the ACE-Fort Project.,
4) Evaluate adoption and contextual factors influencing implementation of the accelerated TB-OVC integration services by CSO staff,
5) Estimate the cost of implementing accelerated TB-OVC integration services under the ACE-Fort Project.

Uganda 2022-11-28 11:40:05 2025-11-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
REGULATING THE MIGRATION OF HEALTH APPS IN UGANDA
REFNo: SS1500ES

The goal of this research is to contribute to the development of a conceptual framework of digital health coloniality as a way of understanding and contesting the digital inequalities that the migration of mHealth data out of Africa cause.

Research Objectives:
- To document future risks of data migration as a form of digital health colonialism while benchmarking on stories of data misuse.

- To establish whether or not contract law reinforces digital health colonialism through the migration of data.
Uganda 2022-11-28 11:18:32 2025-11-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Improving vaccine knowledge and misinformation resistance through the mobile-based game Cranky Uncle: Vaccine Edition
REFNo: HS2519ES

To explore the game's effectiveness across different segments of the population, age groups and education levels.,To evaluate the impact of the mobile game on vaccine knowledge, acceptance and intent and ability to detect misinformation,To explore the resistance/ability to detect different types of misinformation after playing the CU game.,To assess vaccine knowledge, acceptance, and intent after playing the CU game.,To test the effect of the Cranky Uncle mobile game on vaccine knowledge, acceptance, and intent and resistance/ability to detect different types of misinformation through playing the game ,To establish whether the Cranky Uncle game significantly increases vaccine knowledge, acceptance and intent, and resistance to misinformation. If there are areas where the game is ineffective, these findings will inform attempts to improve the game’s performance in these areas.,
Uganda 2022-11-28 11:15:54 2025-11-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bonny Aloka
ID: UNCST-2022-R010624
Development and Evaluation of Nutrient-Dense Composite from Local Food Materials to Manage Moderate Acute Malnutrition (MAM) and Nodding Syndrome in northern Uganda
REFNo: A234ES

3. To investigate the stakeholder perception regarding the nutrient dense composites developed to manage MAM and NS in Acholi and Lango sub-regions,To evaluate the efficacy of the recipes in improving the conditions of clients with MAM and nodding syndrome in Acholi and Lango sub-regions,To test the level of acceptability of the developed composites by the selected mothers/care takers and their children in Acholi and Lango sub-regions,To develop a nutrient dense composites from local food materials to manage MAM and nodding syndrome in Lango and Acholi sub-regions,To develop a nutrient dense composite from local food materials to manage moderate acute malnutrition (MAM) and nodding syndrome in Lango and Acholi sub-regions in northern Uganda.,
Uganda 2022-11-28 11:12:34 2025-11-28 Agricultural Sciences Clinical Trial Non-degree Award
Annet Onzia Aketoko Aketoko
ID: UNCST-2021-R012391
Reducing maternal and congenital syphilis in Uganda. A mixed methods observational study
REFNo: HS2436ES

Qualitative objectives:
1. To understand experiences of women who test positive for syphilis during pregnancy and learn how to better support them.
2. Explore participants’ views on syphilis related birth outcome and treatment of new babies with syphilis.
3. To explore attitudes towards syphilis testing and treatment in male partners of syphilis positive women.
4. To assess barriers and enablers to elimination of maternal and congenital syphilis among stakeholders (health care workers in ANC units, policy makers-MoH).

Quantitative objectives: Through use of routinely collected data
1. To evaluate the birth outcomes in mothers who received syphilis treatment during ANC period.
2. To document number of babies who test RPR/TPHA positive at birth.
3. To document the number of partners that were notified, tested and received treatment for Syphilis
4. To assess the proportion of mothers who tested syphilis positive and those that utilized mhealth

Uganda 2022-11-28 10:36:50 2025-11-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Ring vaccination trial to evaluate the efficacy and safety of Sudan ebolavirus vaccines in Uganda
REFNo: HS2574ES

Probable SUVD and death from confirmed SUVD ,main secondary objective is to assess the safety of the vaccine by monitoring weekly for 21 days any adverse reactions to vaccination and any other serious adverse events,The primary analysis will be of laboratory-confirmed SUVD (from samples taken either while living, or within 48 hours of death),
Uganda 2022-11-23 15:04:05 2025-11-23 Medical and Health Sciences Clinical Trial Non-degree Award
David Mukunya
ID: UNCST-2022-R010707
Cerebral Oximetry, Metabolism and Perfusion for Prognosis And Management of Asphyxiated Neonates (COMPPAMAN) in eastern Uganda: a pilot study
REFNo: HS2551ES

1. To demonstrate the feasibility of monitoring cerebral tissue oxygenation (SO2), cerebral blow flow (CBF) and cerebral oxygen metabolism (CMRO2) among asphyxiated neonates and preterm infants in Jinja Regional Referral Hospital (Jinja RRH).
2. To determine evolution of post-natal cerebral hemodynamics and oxygen metabolism in asphyxiated and preterm infants in the first week of life. Specifically, we will
a. Perform several (daily) NIRS measurements over days on asphyxiated and preterm infants and up to two measurements on term newborns without evidence brain injury.
b. Compare these results in the first week of life with different etiologies of brain injury (hypoxia vs IVH) and controls.
c. Correlate NIRS results with the severity of brain insults determined by ultrasound.
H2.1 Asphyxiated neonates and preterm infants have lower Day 1 CBF and CMRO2 than controls.
H2.2 The decrease in CBF and CMRO2 is in proportion to the severity of brain injury.
3. To determine the predictive values of SO2, CBF and CMRO2 in neonatal mortality in the first week of life.
Gather data as in Aim 2.
H3.1 Cerebral hemodynamics and metabolism in the first week of life are sensitive biomarkers for mortality prediction.
H3.2 Changes in CBF and CMRO2 with age will add to the predictive value of mortality model at one week of life.

Uganda 2022-11-23 12:51:56 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Muteesasira
ID:
Predicting Research Productivity of Academic Staff with PhDs in Universities in Uganda Using Bean's Model
REFNo: SS1521ES

To examine whether the individual variables in Bean’s model mediate the relationship between organisational variables and individual research productivity.,To examine whether organisational variables in Bean’s model predict individual variables.,To examine whether individual variables in Bean’s model predict individual research productivity.,To examine whether organisational variables in Bean’s model predict individual research productivity.,To examine whether Bean’s (1982) model can be used to predict research productivity of a member of academic staff with a PhD in a university in Uganda. ,
Uganda 2022-11-23 12:50:38 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
PROSSY NANTALE NABATTE
ID:
CHARACTERIZATION OF HUMAN PAPILLOMAVIRUS GENOTYPES AND THEIR CORRELATES AMONG WOMEN LIVING WITH HIV ATTENDING ANTIRETROVIRAL THERAPY CLINIC IN MUKONO, UGANDA
REFNo: HS2550ES

To assess how medical history predisposes women living with HIV to Human papillomavirus genotypes in Mukono.,To establish how sexual practices predisposes women living with HIV to Human papillomavirus genotypes in Mukono.,To identify how socio-demographic factors predispose women living with HIV to Human papillomavirus genotypes in Mukono.,To describe the characteristics of Human papillomavirus genotypes among a cohort of WLHIV attending antiretroviral therapy clinic in Mukono, Uganda.,To explore the types and occurrence of HPV infection by genotyping Human papillomavirus among a cohort of WLHIV attending antiretroviral therapy clinic in Mukono, Uganda. ,
Uganda 2022-11-23 12:47:55 2025-11-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
Final evaluation of Our Rights, Our Lives, Our Future (O3) Programme
REFNo: SS1515ES

2. Assess progress against targets set at baseline, validate, and populate the results framework.,4. Provide conclusions and actionable recommendations that can shape future programming and implementation by UNESCO of initiatives to advance education, health and wellbeing of AYP.,3. Identify opportunities, challenges, good practices, and lessons that will be useful for strengthening and enhancing the design and implementation of the next phase of the programme.,1. Ascertain the effectiveness (results/impact), efficiency, and sustainability of the O3Programme,The overall goal of this final evaluation is to provide UNESCO with a systematic assessment of the full implementation period of the O3 Programme (2018-2022) across all 33 countries. This assessment will analyse both expected and unexpected results and how these were achieved; capture challenges faced and measures taken to adapt and respond to these challenges; and extract good practices and lessons learned.,
Uganda 2022-11-23 12:46:32 2025-11-23 Social Science and Humanities Non-degree Award
Emma Ndagire Tina
ID: UNCST-2022-R010041
Assessing the Feasibility of adopting an Acute Rheumatic Fever Diagnosis and Management Algorithm in Uganda
REFNo: HS2542ES

1. Determine how accurately frontline health care providers at selected health facilities in Wakiso district implement the ARF algorithm in Uganda.

2. To determine the factors that will influence the adoption of a novel ARF diagnostic and management algorithm by health care providers at selected community health facilities in Wakiso district.

Uganda 2022-11-23 12:42:36 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
Effectiveness of Intensive Adherence Counselling on Viral Load Suppression among Adolescents and Adults Living with HIV in Uganda
REFNo: HS2553ES

o explore the facilitators of and barriers to repeat VL suppression after IAC completion among adolescents and adults on ART with an initial VL ≥1,000 copies/ml after ≥6 months of ART in Kampala, Uganda using a qualitative case study design (Aim 3),To examine the risk factors for repeat VL persisting at ≥1,000 copies/ml after completing IAC among adolescents and adults on ART with an initial VL ≥1,000 copies/ml after ≥6 months of ART in Kampala, Uganda using a nested case-control study design.,To evaluate the impact of IAC on VL suppression and all-cause mortality among adolescents and adults on ART with VL ≥1,000 copies/ml after ≥6 months of ART in Kampala, Uganda using a regression discontinuity design,
Uganda 2022-11-23 12:41:12 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muniirah Mbabazi
ID:
Gender dynamics in accessing and utilizing Nutrition and WASH services-An exploratory study.RefNO:2022-392
REFNo: HS2544ES

Document key recommendations for advocacy on gender, nutrition and WASH and local and national levels.,Examine how gender dynamics influence access and utilisation of nutrition and WASH services at household and community levels in Maracha and Bugweri districts,Undertake a document review to identify policy gaps in key policy documents on nutrition, WASH and gender in Uganda,To examine how gender dynamics shape access and utilisation of WASH and nutrition services in promoting women’s leadership, decision making, promoting equal and positive gender norms, improving access to resources as well as building contextual research evidence on local resilience, sustainability in Maracha and Bugweri districts in Uganda,
Uganda 2022-11-23 12:39:59 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Hope
ID:
Strengthening national capacity for tsetse control in Uganda
REFNo: SS1490ES

The primary aim of this study is to monitor and assess the implementation of the action plan to strengthen the capacity for implementing tsetse control at COCTU and in the Districts where tiny targets are deployed. This study will follow-up on the capacity strengthening action plan developed in 2017 with the aim to enable COCTU to implement tsetse control for gHAT independently of LSTM.
The aims will be achieved by the following objectives:
1. Conduct semi-structured interviews with key personnel at COCTU and the District level to fully understand the current level of execution of the action plan for strengthening the capacity to for implementing tsetse control in Uganda.

2. Conduct participatory meeting at the District level with COCTU and District staff to collaboratively assess the progress towards the establishment of a stronger and independent tsetse control system in Uganda (based on findings from objective 1).

UK 2022-11-23 12:38:07 2025-11-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Yunia Mayanja
ID:
Improving HIV Prevention among Adolescent Girls and Young Women in Uganda.
REFNo: HS2490ES

The purpose of the PhD project is to determine preferences for biomedical HIV prevention methods among 14-24-year-old adolescent girls and young women (AGYW) at risk of HIV infection and to evaluate a peer support intervention aimed at improving uptake of and adherence to oral pre-exposure prophylaxis (PrEP). Main Study Aims: i) To determine preferences for five biomedical HIV prevention methods among 14-24-year-old AGYW at risk of HIV infection in Kampala, Uganda including oral PrEP, injectable PrEP, vaginal ring, PrEP implant and HIV vaccine. ii) To evaluate a peer support intervention aimed at improving uptake of and adherence to oral pre-exposure prophylaxis (PrEP), the only currently available biomedical HIV prevention method in Uganda. Study Objectives: i. To determine preferences for five biomedical HIV prevention methods among 14-24-year-old AGYW in Kampala, Uganda, and determine factors associated with preference for oral PrEP. ii. To evaluate the effect of a peer support intervention on uptake of and adherence to oral PrEP among 14-24-year-old AGYW at risk of HIV infection in Kampala, Uganda. iii. To evaluate the effect of a peer support intervention aimed at improving oral PrEP uptake and adherence, on sexual behavior and reproductive health outcomes among AGYW in Kampala, Uganda. iv. To explore AGYW perceptions and experiences of the peer support intervention aimed at improving oral PrEP uptake and adherence.
Uganda 2022-11-23 12:36:50 2025-11-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Grace  Kentaro Maria
ID:
FEMININE IDENTITY IN ANTI-COLONIAL STRUGGLES: THE LEGACY OF MUHUMUZA OF NYABINGI MOVEMENT IN KIGEZI, UGANDA
REFNo: SS1144ES

1. To trace the origins of the Nyabingi Movement to 1900 and its goals in the history of Kigezi
2. To assess the contribution of Nyabingi movement in the anti-colonial struggles
3. To examine the contribution of Muhumuza in anti-colonial struggle as a role model in demonstrating women leadership to other women in other struggles
4. To examine the role of oral history in portraying women’s and men’s roles in anti-colonial struggles

Uganda 2022-11-23 12:32:43 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
JOSEPH MWESIGWA SAMUEL
ID:
THE SELECTION OF TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING OPTION BY SECONDARY SCHOOL CANDIDATES IN UGANDA
REFNo: SIR99ES

To establish the awareness of parents of students in secondary schools in Uganda about the TVET option as a career choice for their children.,To investigate the method of course selection by TVET college students in Uganda.,To determine the perception of secondary school teachers in Uganda on TVET as a career choice by the candidates.,To investigate the availability of career guidance information to secondary school candidates on TVET courses in Uganda.,The main objective of the study will be to establish the factors influencing the selection of TVET option by secondary school candidates in Uganda. ,
Uganda 2022-11-23 12:29:54 2025-11-23 Engineering and Technology Non-Clinical Trial Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
Community-based Alternative Learning Environments for Parenting and Pregnant Teens: A Response to Uganda’s Increased Prevalence Due to the Impact of the COVID-19 Global Pandemic
REFNo: SS1487ES

This research aims to conduct a participatory assessment of factors that enhance adoption of alternative education environments for parenting and pregnant teens by involving communities in reflecting on and defining special needs for school re-entry and providing for second-chance education after pregnancy in Uganda.,To comprehensively disseminate the recommendations and guidelines for policy uptake,To co-create policy recommendations for community-based alternative education environments for parenting and pregnant teens,To conduct participatory multi-level needs assessment and policy pecommendations ,
Uganda 2022-11-23 12:28:32 2025-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
Emmy Okello
ID: UNCST-2020-R009792
Accelerating Delivery of rheUmatic heart disease preventive iNterventions in Uganda (ADUNU)
REFNo: HS2470ES

Objective 1: Demonstrate the impact of ADUNU, using the RE-AIM framework to assess program Reach,
Effectiveness, Adoption, Implementation, and Maintenance. Objective 1 has five sub-objectives:
a) Reach – Use echocardiography to increase the proportion of individuals with RHD who are detected, including identification of sub-groups not reached (target: 50% Kitgum district] or 25% [Amuru district] detected).


b) Effectiveness – Achieve goals in (1) registry enrollment (target: 90% of those diagnosed by RHD testing), (2) retention (target: 90% of those enrolled), and (3) adherence (target: 90% of those retained).

c) Adoption – Assess the proportion of healthcare facilities and providers that adopt ADUNU and understand barriers and facilitators to adoption success.

d) Implementation – Assess the proportion of healthcare providers and facilities demonstrating high fidelity to the relevant ADUNU components and protocols in which they have been trained and reasons for suboptimal performance.

e) Maintenance – Understand the (1) proportion of facilities and providers continuing to implement ADUNU as designed, and (2) sustainment of retention and adherence levels among individuals enrolled in the registry at 24 months post-introduction

Objective 2: Estimate the cost-effectiveness and budget impact of ADUNU. This objective will build on the first objective and will use standard methods for economic evaluation of health programmes.

Uganda 2022-11-23 12:26:29 2025-11-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Filippo Grisolia
ID:
One for all and all for cash? An inquiry into social network and collective action effects of cash transfers in rural Uganda
REFNo: SS1467ES

Focus on social capital, agency and collective action measures,Focus on climate change adaptation and mitigation patterns,Investigate CT effects,
Italy 2022-11-17 3:55:31 2025-11-17 Social Science and Humanities Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
EFFICACY AND SAFETY OF DIHYDROARTEMISININ-PIPERAQUINE (EURARTESIM) FOR TREATMENT OF UNCOMPLICATED P. FALCIPARUM MALARIA IN ADULT PATIENTS WITH COVID-19 CO-INFECTION: AN OPEN LABEL RANDOMISED PILOT CLINICAL TRIAL (EMCOS CLINICAL TRIAL)
REFNo: HS2563ES

To evaluate the incidence of adverse events in adult participants with uncomplicated P. falciparum malaria and COVID-19 coinfection receiving DHA/PPQ treatment or Artemether – lumefantrine treatment. ,To determine the efficacy of DHA-PPQ in treatment of adult patients suffering from uncomplicated P. falciparum malaria with COVID-19 coinfection.,To assess the therapeutic efficacy and safety of DHA-PPQ for the treatment of uncomplicated P. falciparum malaria- COVID-19 co-infection.
Uganda 2022-11-17 18:12:26 2025-11-17 Medical and Health Sciences Clinical Trial Non-degree Award
TWAHA NAJJA -
ID:
“Performance of Mergers of mobile telecommunication operators in Uganda.: Does the management of employees’ expectations matter in influencing performance.” Ref No. MUST-2022-614
REFNo: SS1493ES

The general objective of this study is to examine the extent to which the management of a combination of employee communication and employee participation, herein referred to as employees’ expectations, influence post-merger and acquisition performance of mobile telecommunication operators in Uganda.
Specific objectives of the study
1. To determine the effect of management of employee communication on post- merger and acquisition performance of mobile telecommunication operators in Uganda.
2. To determine the effect of management of employee participation on post- merger and acquisition performance of mobile telecommunication operators in Uganda.
3. To establish the extent to which employee satisfaction affects the relationship between management of employee communication and post-merger and acquisition performance of mobile telecommunication operators in Uganda.
4. To establish the extent to which employee satisfaction affects the relationship between management of employee participation and post-merger and acquisition performance of the mobile telecommunication operators in Uganda.


Uganda 2022-11-17 18:03:32 2025-11-17 Social Science and Humanities Non-Clinical Trial Degree Award
MOSES EGESA
ID: UNCST-2025-R015361
Characterization of protein and glycan epitopes recognised following controlled human infection with Schistosoma mansoni in an endemic population (SmCHI-Epitope)
REFNo: HS2072ES

The aim is to identify candidate molecules (proteins and peptide or glycans) associated with protection against controlled human infection with Schistosoma mansoni in an endemic population. This study will investigate
1. antibody responses to whole recombinant proteins and peptide epitopes of surface- exposed and secreted proteins of S. mansoni after CHI-S and relate this to whether volunteers get infected or not following exposure to CHI-S
2. specific anti-glycan antibody responses after CHI-S and relate this to whether they get infected or not following exposure to CHI-S

Uganda 2022-11-17 17:58:46 2025-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michiel De Haas Alexander
ID: UNCST-2022-R009315
Mapping the Cotton Boom in Eastern Uganda c 1910-1970: Temporal and Spatial Patterns and Economic Legacies
REFNo: SS1514ES

Main objective: the creation of a geocoded database of cotton ginneries in Uganda from the establishment of the first ginnery in 1904 until today



Specific objectives:

1. map the spatial distribution and characteristics of cotton ginneries in Uganda over the period 1904 until 2022 Delete

2. Link geographical variables such as soil quality, terrain ruggedness, rainfall patterns, cotton suitability, and suitability for other crops, tsetse prevalence and distance to waterbodies to the spread of ginneries, conceptualized as the likelihood that a grid-cell with specific characteristics is ‘treated’ with the appearance and disappearance of a ginnery. Delete

3. Link ‘treatment’ with ginneries to contemporary living standards and livelihood strategies today: did historical proximity to a cotton ginnery have long-term effects on the level of income, the sources of income (agricultural and non-agricultural) and agricultural productivity?
Netherlands 2022-11-16 10:57:10 2025-11-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARD™ Q Covid-19 Ag Home Test Laymen Study including Usability." Clinical Performance Study Plan - CPSP nr. BSS-CPH 22-040"
REFNo: HS2536ES

The objective of this laymen study is to establish the usability of the STANDARD Q COVID-19 Ag Home Test in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2022-11-16 10:56:01 2025-11-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
Evaluation of “Inclusive Playful Parenting for a Brighter Childhood” in Uganda – a Quasi-experimental study.
REFNo: SS1498ES

• To conduct a baseline and final evaluation to document the current status and the change in: child development in motor (fine, gross), language, cognitive, social-emotional domains; parenting practices in responsive caregiving, early learning, safety security; and caregiver mental well-being scores;
• Compare and understand the impacts of high, medium, and low dose of integrated Playful Parenting interventions on caregiver and child level outcomes;
• Learn about the efficiency, feasibility of engaging different community actors, workforces to reach, influence, and support parents in communities, sustainability drivers to promote and sustain Playful Parenting;

Uganda 2022-11-16 10:54:43 2025-11-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
CLARE KYOMUHENDO
ID:
The Burden of Prenatal and Postpartum Depression among Women Living with HIV in Kampala and Wakiso, Uganda
REFNo: SS1488ES

1. Examine the prevalence of prenatal and postpartum depression in women living with HIV in Kampala and Wakiso, Uganda.
2. Assess the knowledge of prenatal and postpartum depression of women living with HIV in Kampala and Wakiso, Uganda.
3. Explore the prenatal and postpartum experiences of Women Living with HIV in Kampala and Wakiso, Uganda.
4. Investigate the relationship between perinatal status and depression among Women Living with HIV in Kampala and Wakiso, Uganda.
5. Examine the determinants of prenatal and postpartum depression among women living with HIV in Kampala and Wakiso, Uganda.
Uganda 2022-11-16 10:49:34 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Rikke Fischer Horne
ID:
Availability of Reproductive Healthcare Among Women in Gulu
REFNo: SS1513ES

Gain insight into women's experience of reproductive health care at the health units,Share knowledge with health workers and other interested parties,Enhance knowledge of reproductive healthcare availability.
Denmark 2022-11-16 10:46:38 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Mateusz Krawczyk Marek
ID:
Patterns of refugees' hybrid identity in perspective of their subjective ability to rebuild the living conditions. A case study of Nakivale Refugee Settlement in Uganda
REFNo: SS1481ES

1. develop, based on empirical research and adopted explanatory procedures, an integral theory of the hybrid identity of refugees
2. define and assess the cognitive, emotional, and volitional abilities of a human being, which enable them to undertake causative actions
3. Assessment of the extent to which aid organizations respond to the needs of refugees
Poland 2022-11-16 10:42:20 2025-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
Lukwago Ismail
ID:
A THEORETICAL MODEL FOR ADOPTION OF E-LEARNING IN HIGHER INSTITUTIONS OF LEARNING: A PERSPECTIVE OF SELECTED PRIVATE UNIVERSITIES IN UGANDA
REFNo: SIR150ES

i. To identify the adoption drivers of e-learning systems in private universities in Uganda.
ii. To investigate the extent to which ICT facilities are in use by the students in private universities in Uganda.
iii. To develop a theoretical model for adoption drivers of e-learning systems in private universities in Uganda.
iv. To validate the developed theoretical model for adoption drivers of e-learning systems in private universities in Uganda.

Uganda 2022-11-15 3:46:00 2025-11-15 Engineering and Technology Non-Clinical Trial Degree Award
Annet Musiimenta
ID:
SCHOOL MANAGERS COLLABORATION WITH UNIVERSITIES FOR TEACHER EDUCATION SUPPORT DURING SCHOOL PRACTICE
REFNo: SS1468ES

1. To explore the roles school managers perform during school practice supervision 2. To assess the roles university supervisors take up in collaboration with schools during School Practice supervision 3. To explore student teacher’s perceptions regarding the support of school managers and university supervisors during school practice.
Uganda 2022-11-15 3:44:24 2025-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
Suubi-Mhealth: A mobile health intervention to address depression and improve ART adherence among Youth living with HIV (YLHIV) in Uganda
REFNo: SS1442ES

The overall goal of this proposal is to develop a mobile health intervention (hereafter “Suubi-Mhealth”) for use among Ugandan youth with comorbid HIV and depression, taking into account their unique contextual, cultural, and developmental needs. This digital therapy intervention (mobile app) will apply user-centered design methodologies and will be based on the cognitive-behavioral therapy (CBT) tenets found to improve depression among individuals with HIV.

The study will be conducted in two phases (R21 and R33) as specified below

Phase 1. R21 Aim 1: Develop and iteratively refine an intervention protocol for Suubi-Mhealth based on formative work to understand the needs of depressed YLHIV, ages 14-17. We will conduct four focus groups, each with 6-8 depressed YLHIV and two focus groups with health care providers, recruited from clinics across the greater Masaka region of Uganda for feedback on proposed intervention content and methods to increase participation and retention.

R21 Aim 2: Based on the results of Aim #1, we will explore the feasibility and acceptability of Suubi- Mhealth for use with depressed YLHIV on a small scale (N= 30) to inform subsequent refinement for the larger phase of this project (R33 phase).

Phase 2. R33 Aim 1: Pilot test the preliminary impact of Suubi-Mhealth versus a waitlist control group (to receive the intervention after the active treatment condition), on reducing depression (primary outcome) and improving ART adherence, mental health functioning, quality of life, and lowering HIV stigma (secondary outcomes).

R33 Aim 2: Qualitatively examine barriers and facilitators for integrating Suubi-Mhealth into health care settings for depressed YLHIV.

Uganda 2022-11-15 3:42:47 2025-11-15 Social Science and Humanities Clinical Trial Non-degree Award
Patience Atumanya
ID:
FEASIBILITY AND SAFETY OF SEGMENTAL THORACIC SPINAL ANESTHESIA FOR OPEN GASTROSTOMY: Experience from an Oncology Center during the COVID-19 pandemic.
REFNo: HS2215ES

1. To evaluate the feasibility of segmental thoracic spinal anesthesia for oncology patients undergoing open gastrostomy.
2. To assess incidence of spinal cord injury potentially associated with segmental thoracic spinal anesthesia.

Uganda 2022-11-15 3:38:33 2025-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nestor Atukwatse
ID:
Capacity needs assessment on gender/youth responsive and inclusive planning, budgeting, data for decision-making and Sexual Reproductive and Health supportive supervision.
REFNo: SS1516ES

To conduct training for the District Health Management Teams and Technical Working Groups on gender/youth responsive and inclusive planning and budgeting, data for decision making and SRH supportive supervision.,To develop/adapt existing training modules on gender/youth responsive and inclusive planning and budgeting, data for decision making and Sexual, Reproductive and Health supportive supervision based on the findings from the Capacity gaps assessment.,To assess the capacity gaps among the District Health Management Teams and Technical Working Groups in managing and coordinating gender/youth responsive and inclusive planning, budgeting, data for decision-making and Sexual, Reproductive and Health supportive supervision. ,
Uganda 2022-11-11 17:26:00 2025-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
William Buwembo
ID: UNCST-2022-R009661
Oral Papilloma Virus, Microbiota and Cancer in People Living with HIV (OHPVMC)
REFNo: HS2541ES

Aim 1: To characterize and understand oncogenic Oral Human Papilloma Virus (OHPV) infections in People Living With HIV (PLWHIV)in reference to non-clearance of OHPV. To test our hypothesis that the oncogenic OHPV type 16 infections in PLWHIV are associated with non-clearance, we will use a prospective cohort design to characterize and understand OHPV infections in PLWHIV.
Aim 2: To determine the differences in the periodontitis associated bacteria of PLWHIV with or without OHPV. To test our hypothesis that OHPV is associated with the presence of periodontitis associated oral bacteria, we will compare the patterns of periodontitis (red and orange complex) associated bacteria in PLWHIV in the presence or absence of OHPV infections.

Uganda 2022-11-11 17:24:02 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
Willingness to take COVID-19 vaccine and uptake of locally adapted COVID-19 prevention measures among high-risk populations in Malaba and Mutukula points of entry
REFNo: HS2530ES

i) To assess willingness to take the COVID-19 vaccines among high-risk populations in Malaba and Mutukula points of entry.
ii) To explore facilitators and barriers to willingness to take COVID-19 vaccines among high-risk populations in Malaba and Mutukula points of entry.
iii) To assess uptake of locally adapted COVID-19 prevention measures among high risk populations in Malaba and Mutukula points of entry.
iv) To explore facilitators and barriers of locally adapted COVID-19 prevention measures among high-risk populations in Malaba and Mutukula points of entry.

Uganda 2022-11-11 17:21:54 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kizito BADA
ID:
FOSTERING DIGITAL LEARNING ENVIRONMENT FOR ADOLESCENT REPRODUCTIVE HEALTH EDUCATION
REFNo: SS1489ES

Specific Objectives
1) To sensitize and introduce a select sample of 14 teachers from 7 schools to multimedia teaching material and digital stories for teenage reproductive and mental health education with the goal of expanding teachers’ knowledge and skills in use of digital stories and multimedia content as pedagogical tools.
2) To provide hands on training on e-content curriculum creation, multimedia content development, digital stories development and digital game design for teenage reproductive and mental health education.
3) To implement multimedia educational content, multimedia content and digital stories in the 7 schools and train a total of 400 students in reproductive health education.
4) To evaluate effectiveness and impact of cartoon-based stories and multimedia educational materials on the higher level cognitive skills developent of the students.
5) To mentor 10 junior teaching staff in action research through participation in project implementation activities and disseminate the outcomes of the project in the form of online resources, academic and professional publications, conference presentations as well as policy briefs to the government agencies.

Uganda 2022-11-11 17:20:33 2025-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jonathan Marino
ID:
How the social and material conditions of teaching influence early grades teachers’ implementation of reading pedagogies
REFNo: SS1509ES

To understand how social and material conditions shape the way teachers think about these reading pedagogies and their own teaching practice.,To understand how early primary educators in Uganda make sense of various reading pedagogies they are asked to undertake, such as mother-tongue instruction and child centered pedagogies.,To understand what are the social and material conditions of teaching experienced by early primary educators in Uganda. and how the COVID-19 pandemic has influenced these conditions.,The goal of this study is to explore how early primary teachers in Uganda make sense of and implement new pedagogical approaches to teaching reading and how the social and material constraints of their teaching environment influence their reading instruction.,
USA 2022-11-11 17:18:21 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
GRACE  MUSINGUZI
ID:
Relationship between family support and self efficacy on resilience among school going adolescent victims of trauma in Kampala, Uganda
REFNo: SS1475ES

Purpose of the study The purpose of this study is to examine the relationship between family support, self-efficacy and resilience among adolescents facing trauma in Kampala, Uganda. Specific objectives 1.To find out the prevalence of trauma among adolescents in Kampala District. 2.To find out the relationship between family support and resilience among adolescent trauma victims. 3.To find out the relationship between family breakdown and resilience among adolescent trauma victims. 4.To find out the relationship between self-efficacy and resilience among adolescent victims of trauma. 5.To explore strategies that can be put in place to foster resilience among traumatised adolescents in broken families in Kampala District.
Uganda 2022-11-11 17:16:15 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
Suubi+Adherence4Youth: Optimizing the Suubi Intervention for Adherence to HIV Treatment for Youth Living with HIV in Uganda
REFNo: SS1449ES

The proposed Suubi+Adherence4Youth study seeks to unpack the Suubi intervention to identify the most impactful and sustainable components: economic vs. psychosocial components, for adolescents living with HIV (ALHIV) across the HIV care continuum. The Suubi intervention was tested as a package of four components: 1) Financial Literacy Training (FLT); 2) Incentivized Matched Youth Savings Accounts (YSA) with income-generating activities (IGAs); 3) a manualized and visual-based intervention for ART adherence and stigma reduction; and 4) Engagement with HIV treatment-experienced role models. We propose a factorial experiment to unpack and optimize the Suubi intervention to enhance scale up in health systems using the multi-phase optimization strategy (MOST) -an engineering-inspired intervention framework. Our ultimate goal is to build Suubi version 2.0 that meaningfully improves viral suppression while performing efficiently, affordably, and at scale for a sustained impact.

Aim 1. Conduct a factorial experiment (optimization trial) to test the main effects of each of the four Suubi intervention components and combinations of components (interactions) on viral suppression (primary outcome).

Aim 2. Test mediators and explore moderators that explain and modify the relationship between each of the four Suubi intervention components and viral suppression.

Aim 3. Compare the cost and cost-effectiveness of each of the four Suubi intervention components and every combination of components.

Uganda 2022-11-11 17:11:59 2025-11-11 Social Science and Humanities Clinical Trial Non-degree Award
Moses Adriko
ID: UNCST-2019-R001787
Field testing of a portable low-cost diagnostic for the automated diagnosis of soil transmitted helminth infections from Kato-Katz thick faecal smears
REFNo: HS2431ES

Our plan of work is to travel to Uganda, where we will initially stay in Kampala, Uganda to prepare any equipment that needs to be purchased in-country (including reagents, consumables and treatment), and engage with stakeholders at the MOHU and Vector Control Division (VCD). We will then embark on a 14-day field study, travelling to an endemic area in the Tororo district. Samples will be taken from patients and analysed using gold standard diagnostic methods and the novel portable diagnostic. Clinical diagnoses will be made using gold standard microscopy by trained technician, and the efficacy of the investigational device will be compared to these diagnoses. Feedback of technicians will also be gathered during practical demonstrations, to inform a development and translation roadmap.
Uganda 2022-11-11 17:02:30 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
The implementation of ambulatory surgery in a rural setting in Eastern Uganda
REFNo: HS2489ES

Identify factors contributing to utilization of surgical care,Develop new strategies to improve ambulatory surgery based on the results of these studies,Access the logistics and infrastructure needed to run an ambulatory surgery centre,Access surgical outcomes performed at an ambulatory surgery centre,Assess preoperative considerations for ambulatory surgery,Assess differences in outcomes of surgeries at Kyabirwa Surgical Centre,Longitudinally collect an extensive medical history, intra-operative details, clinical outcomes of the patients undergoing ambulatory procedure at KSC,Understand the prevalence of surgical diseases in the community, as compared to the prevalence of surgical diseases treated in the Centre,Analyze the data for correlative factors. The correlative factors could be the impact of demographics, medical treatment history, and/or surgical technique,Understand the needs of the patient and the community in providing better healthcare,
Uganda 2022-11-11 17:01:15 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RICHARD NABONGO
ID:
EXPERIMENTING WITH POTTERY DESIGNS TO PRESERVE FRUITS AND VEGETABLES IN THE RURAL COMMUNITIES OF JINJA AND IGANGA DISTRICTS IN UGANDA
REFNo: SS1084ES

The aim of this study is to explore and experiment with pottery design to preserve fruits and vegetables in the rural communities of Jinja and Iganga districts through creation of a practice based pottery product.,To establish a practice-based pottery prototype product for selected villages of Jinja and Iganga districts.,To evaluate the extent to which modern technology has influenced food production and preservation practices in the local communities of Jinja and Iganga districts.,To examine the contribution of pottery to the local communities in Jinja and Iganga districts in Uganda.,To assess the influence of pottery design in today’s contemporary world. ,
Uganda 2022-11-11 16:59:14 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Namulema Edith
ID:
Feasibility of using Continuous Positive Airway Pressure via the ‘LeVe CPAP System’ among Children with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A mixed methods study
REFNo: HS2478ES

1) To assess the acceptability of the LeVe CPAP system to deliver continuous positive airway pressure among children with acute hypoxemic respiratory failure at Mengo Hospital Uganda.
2) To assess the safety of LeVe CPAP system among children with acute hypoxemic respiratory failure at Mengo Hospital Uganda.

Uganda 2022-11-09 13:49:10 2025-11-09 Medical and Health Sciences Clinical Trial Non-degree Award
Zula Namubiru
ID:
HARNESSING FISHERS' KNOWLEDGE FOR SUSTAINABLE FISHERY ON LAKE VICTORIA: A CASE OF KIGUNGU FISHING GROUND WAKISO DISTRICT
REFNo: SS1511ES

1.To assess fishers’ perceived attitude, knowledge and practice on illegal fishing on Lake Victoria
2. To engage fishers especially the youth on what they can do and how best they can be enabled to sustain the fishery resource
3. To discuss with fishers’ wives/ spouses and female fish smokers on what they can do and how best they can be enabled to sustain the fishery resource
4. To understand how different stakeholders can best support fishers for the sustainable conservation of the fishery resources
Uganda 2022-11-08 14:17:17 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
Francis Garuzooka John
ID:
Work and learning experiences of graduates from Technical and vocational Training Institutions in Uganda. A case Study
REFNo: SS1507ES

is to understand the work and learning experiences of graduates of TVET institutions in Uganda with a view of proposing strategies for recognizing and validating non-formal workplace learning and improving productivity,4. To Evaluate how TVET graduates balance work, training apprentices and learning at their workplaces.,3. To3. To analyse the progression of TVET graduates to higher level competences and qualifications as they work. ,2. To explain the relevance of the knowledge and skills acquired by graduates of TVET institutions to the current tasks they perform at their workplaces. ,1. To find out how TVET institutions prepare their learners for work and continuous learning,
Uganda 2022-11-08 14:14:34 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
Enock Matovu
ID:
COntrolling and progressively Minimizing the Burden of Animal Trypanosomiasis in Uganda [COMBAT-U]
REFNo: A237ES

i. To determine the burden, socioeconomic importance, factors driving transmission network pathways of AAT and the knowledge gaps that exist in AAT vector identification
ii. To determine the differencesin the immune responses, metabolic and genetic profiles in trypanotolerant and susceptible cattle breeds
iii. To identify molecular determinants of trypanocidal drug resistance in Trypanosoma congolense field isolates in order to develop novel molecular test(s) to detect such drug resistant strains.

Uganda 2022-11-08 14:11:16 2025-11-08 Agricultural Sciences Non-Clinical Trial Non-degree Award
Harriet Opondo
ID: UNCST-2022-R010927
Mental Health needs Assessment of Children ages 0-5 years Living with HIV in an Urban setting in Uganda.
REFNo: SS1484ES

1. To describe and assess the spectrum of mental health needs (magnitude and prevalence) among children living with HIV ages 0-5 years. 2. To establish the awareness of health care workers regarding mental health needs among CLHIV (0-5) years and establish existing resources and capacities to respond to these needs. 3. To explore parent training needs of parents/primary caregivers of CLHIV (0-5) years who are presenting with mental health needs.
Uganda 2022-11-08 14:09:12 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
lydia Bunalema
ID: UNCST-2020-R014729
Identification and validation of anti-plasmodial activity and artemisinin pharmacokinetic enhancement potential of medicinal plants used by Ugandan communities to treat malaria symptoms
REFNo: NS431ES

To formulate a herbal product for treatment of malaria To establish the protective effect of above herbal extracts against metabolic clearance of Dihydroartemisinin in a rabbit model To determine the susceptibility (RSA0-3h and IC50) of Plasmodium falciparum to the five most common herbal extracts used in treatment of malaria symptoms across Uganda To establish through a systematic review and ethnobotanical survey medicinal plants used in treatment of malaria symptoms in communities To investigate the anti-plasmodial activity and artemisinin pharmacokinetic enhancement potential of medicinal plants used by communities across Uganda in treatment of malaria symptoms,
Uganda 2022-11-08 14:05:34 2025-11-08 Natural Sciences Non-Clinical Trial Non-degree Award
Wilson Mugizi
ID: UNCST-2022-R009877
Resource Based View Approach in Implementation of E-Learning in Selected Ugandan Public Universities
REFNo: SS1454ES

i. To examine the relationship between universities tangible resources and e-learning implementation during and beyond Covid-19 pandemic era in Uganda
ii. To evaluate the relationship between the universities intangible resources and e-learning implementation during and beyond Covid-19 pandemic era in Uganda.
iii. To assess the relationship between universities capabilities and e-learning implementation during and beyond Covid-19 pandemic era in Uganda.
iv. To suggest the strategies for management of e-waste resulting from implementation e-learning implementation.

Uganda 2022-11-08 14:03:00 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kananura  Muhumuza Rornald
ID: UNCST-2019-R000239
Improving Quality and Use of Newborn Indicators (IMPULSE): A two-phase project to describe and improve the quality and use of facility-level newborn indicators in African countries.
REFNo: HS2473ES

1. Map newborn indicator data availability in existing routine health information systems (RHIS) 2. Assess newborn key indicator data quality in existing RHIS. 3. Understand newborn indicator data use by different stakeholders in existing RHIS. 4. Analyse technical, organizational and behavioural enabling factors in RHIS to improve newborn indicator data quality and use 5. Measure the effect of the COVID-19 pandemic on newborn RHIS data
Uganda 2022-11-08 14:00:16 2025-11-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Ekwan Uzu
ID: UNCST-2022-R009805
Co-creating a Culturally Relevant Programme for Enabling Participation of Children with Brain Injury in Uganda (CEBU)
REFNo: HS2509ES

To explore the participants’ thoughts, feelings, and perceptions of the current intervention programme at the KWB-HTC.,To generate a culturally relevant programme (CRP) for enabling participation of children with brain injury in the KWB-HTC.,To describe the consequences and limitations of a CRP for children with brain injury in the KWB-HTC.,To describe how the participants co-create a Culturally Relevant Programme (CRP) enabling participation of children with brain injury in the KWB-HTC.,
Uganda 2022-11-08 13:54:18 2025-11-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
STRENGTHENING THE HEALTH SECTOR SYSTEMS WORKFORCE IN THE PREVENTION AND RESPONSE TO VIOLENCE AGAINST CHILDREN: A PILOT PROJECT IN MAYUGE AND AMURU DISTRICTS
REFNo: SS1497ES

3. To measure impact and key outcomes of these interventions on health worker knowledge, attitudes, and competences in VAC service improvement and delivery.,2. To deliver a package of VAC interventions that is realistic, relevant and acceptable to health workers, including leadership development, training, dissemination of existing guidelines and the use of lay workers as case advocates to provide basic information and escort survivors to various referral points.,1. To explore, both qualitatively and quantitatively, the knowledge, practices and attitudes towards VAC prevention and response work, services offered, roles and current capacities, and barriers to involvement. ,Our aim is to collaboratively design and test the acceptability, feasibility, and scalability of a health worker capacity building and leadership strengthening VAC intervention in Mayuge and Amuru districts in eastern and northern Uganda.,
Uganda 2022-11-08 13:49:21 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Mugagga Isaac
ID:
Empowerment Beyond the Household: Measuring and Comparing the Collective Agency of Groups and Individuals
REFNo: A194ES

a) Measure the degree to which group members and the group as a whole verbally express and/or behaviorally indicate a sense of collective agency
b)Identify features of groups and external factors, including targeted interventions, that can successfully increase women’s collective agency
c)Understand how intersectionality affects the ability of women and men of different backgrounds to participate in, and benefit from, group processes
d)Understand the impacts of increased collective agency in terms of outcomes for individual women and their groups
e)Better understand linkages between empowerment within and outside the household


Uganda 2022-11-08 13:36:34 2025-11-08 Agricultural Sciences Non-Clinical Trial Non-degree Award
Andreas Madestam
ID:
Closing the gender Gap in Agriculture: Experimental Evidence from Uganda
REFNo: SS1360ES

To evaluate if the gender gap in agriculture productivity is caused by lack of soft skills among female farmers in Uganda.
Sweden 2022-11-08 13:32:20 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
A Phase II Multicenter Study of Pomalidomide Monotherapy in HIV-Positive Individuals with Kaposi Sarcoma (KS) in Sub-Saharan Africa (SSA)
REFNo: HS2367ES

To evaluate if changes in serum cytokine levels correlate with clinical response.,To assess the effect of pomalidomide treatment on serum cytokine levels.,To evaluate the effects of pomalidomide monotherapy on standard measures of HIV control, i.e., CD4 counts and HIV viral loads, in this participant population.,To determine if pomalidomide monotherapy induces a minimal level of antitumor efficacy to justify its further development for HIV-associated KS in sub-Saharan Africa and is safe and tolerable.,
Uganda 2022-11-08 13:27:55 2025-11-08 Medical and Health Sciences Clinical Trial Non-degree Award
Simons  Ezajobo
ID: UNCST-2021-R012010
Uptake of HIV Testing Services through Assisted Partner Notification (APN) among Men in Wakiso District.
REFNo: HS2537ES

2.To understand the preferred partner notification approaches to help men feel more comfortable and confident in getting tested for HIV.,1.To assess the experience of males during the process of HIV testing services provision.,To identify barriers and facilitators to HIV testing among men in Uganda,
Uganda 2022-11-08 13:23:56 2025-11-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
PHARMACOKINETICS OF DRUGS USED TO TREAT UNCOMPLICATED MALARIA IN BREASTFEEDING MOTHER-INFANT PAIRS
REFNo: HS2392ES

Primary Objectives;
1. To define transfer of lumefantrine and its active metabolite, desbutyl-lumefantrine from mother to breastfed infant.
2. To determine the clearance, AUC, and volume of distribution of lumefantrine and desbutyl-lumefantrine
Secondary Objectives
1. To describe covariates influencing drug exposure in maternal plasma, breast milk and infant plasma
2. To develop a population pharmacokinetic model including the breast and the infant as compartments, which will both enable optimal use of sparse data from future studies and enable simulations of different doses or combinations.
3. To assess depression and anxiety levels among breastfeeding mothers on first line antimalarial drugs.
4. Beliefs about medicines in breastfeeding mothers receiving antimalarial treatment



UK 2022-11-04 16:05:41 2025-11-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
Innovations for continuity of HIV, TB and malaria services during the COVID-19 pandemic in Uganda
REFNo: HS2477ES

The goal of this research is to collate and assess the impact of innovative people-centred and community-based approaches adopted during the covid-19 pandemic to ensure continued HIV, TB and malaria services in Uganda. This will inform the ongoing and future pandemic/epidemic response actions.
Specific objectives are:
1. To identify innovations used to mitigate the impact of the covid-19 pandemic on the provision, access, and utilization of HIV, TB and Malaria services in Uganda.
2. To assess the impact of innovations to mitigate the impact of the COVID-19 pandemic on HIV, TB, and Malaria services provision, access, and utilization.
3. To document the lessons learnt in innovating to mitigate the impact of COVID-19 on HIV, TB and malaria services in Uganda during the pandemic.

Uganda 2022-11-03 12:21:51 2025-11-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Albert Munyeshyaka
ID:
Cosmological studies in modified Gauss-Bonnet gravity
REFNo: NS434ES

To determine evolution of overdensities and velocity perturbations in f (G) grav- ity,To analyse perturbations of a Chaplygin gas model in f (G) gravity,To analyse covariant velocity and overdensities of quasi-Newtonian cosmological model in f (G) gravity,To derive evolution of 1 + 3 covariant linear perturbation equations in f (G) gravity.,The aim of this study is to explore cosmological studies in modified Gauss-Bonnet gravity.,
Rwanda 2022-11-03 12:09:30 2025-11-03 Natural Sciences Non-Clinical Trial Degree Award
MICHAEL JACKSON WAKWABUBI
ID:
Financial distress in local governments in Uganda
REFNo: SS1429ES

To establish the relationship between local government delivery system and financial distress in local governments in Uganda To assess the relationship between revenue concentration and financial distress in local governments in Uganda To examine the relationship between revenue concentration, local governance, corruption and LG delivery system in local governments in Uganda To assess the mediating effect of LG delivery system in the relationship between revenue concentration, local governance, corruption and financial distress in local governments in Uganda To establish the relationship between local governance and financial distress in local governments in Uganda To establish the relationship between corruption and financial distress in local governments in Uganda
Uganda 2022-11-03 11:38:10 2025-11-03 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
‘Remdesivir: Monitored Emergency Use for Filoviral Disease’
REFNo: HS2531ES

To offer patients with laboratory-confirmed filovirus disease (e.g. Ebola virus [EBOV], Bundibugyo virus [BDBV], Marburg virus [MARV] disease, and Sudan virus [SUDV]) under the clinical supervision of the protocol Principal Investigator or their designated physicians, access to treatment with Remdesivir under monitored conditions.
Uganda 2022-11-02 17:30:52 2025-11-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
Efficacy, Safety and Effectiveness of Injectable Cabotegravir/Rilpivirine in Improving HIV Control in Sub-Saharan Africa: A pragmatic Phase 3 Open-label Randomized Controlled Trial.
REFNo: HS2475ES

Primary objective:
To demonstrate the non-inferior efficacy of switching to every 2 months (Q2M) intramuscular (IM) injection of cabotegravir (CAB) long acting (LA) plus rilpivirine (RPV) LA compared with continuation of first-line oral ART over 12 months in people living with HIV (PLHIV) with a history of, or at risk of, sub-optimal HIV control.

Secondary objectives:
1) To demonstrate the antiviral activity and the impact on retention in HIV care of switching to Q2M CAB LA + RPV LA compared with continuation of oral ART over 12 and 24 months in PLHIV with a history of, or at risk of, sub-optimal ART adherence or engagement in care.

2) To demonstrate the immunological activity of switching to Q2M CAB LA + RPV LA compared with continuation of oral ART over 12 and 24 months in PLHIV with a history of, or at risk of, sub-optimal ART adherence or engagement in care. This will be measured through change in CD4+ T cell count and incidence of HIV disease progression.

3) To evaluate the safety and tolerability of switching to Q2M CAB LA + RPV LA compared to continuation of oral ART.

4) To assess genotypic viral resistance in participants experiencing protocol-defined confirmed virological failure (plasma HIV-1 RNA >200 c/ml) and its impact on future treatment options including proportion who resuppress on dolutegravir.

5) To evaluate the effect of Q2M CAB LA + RPV LA on health-related quality of live, treatment satisfaction and treatment adherence. To describe cost-effectiveness and acceptability of the regimen.

Uganda 2022-11-02 17:27:11 2025-11-02 Medical and Health Sciences Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
Violence Against Children and Youth Surveys (VACS) Cognitive Testing of Gender Attitude and Norm Measures Among Youths in Humanitarian Settings in Uganda
REFNo: SS1486ES

• To evaluate participants’ interpretation of the gender measures, consider and weigh relevant aspects of their lives and formulate a response based on those considerations.
• To test and refine gender measures that are understandable to 13-24-year-old study participants for inclusion in the core VACS questionnaire and future VACS administration.
• To identify context specific relevance of proposed gender measures in the administration of VACS in a humanitarian setting within Uganda.

Uganda 2022-11-02 10:14:05 2025-11-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Achilles Kiwanuka
ID:
Comparative Analysis of Health Information Systems Approaches in Use in Uganda
REFNo: HS2521ES

1. Describe the achievements, challenges, lessons learned and prospects for using the paper based HMIS, Smart Paper Technology and fully digitalized approaches for managing health information in Uganda.
2. Assess performance, usability and functionality of the fully digitalised and paper based HMIS approaches at the community level and Smart Paper Technology at the health facility level using the Performance of Routine Information System Management (PRISM) framework.
3. Analyze the cost benefit of using Smart Paper Technology and fully digitalised approaches of health information systems in Uganda.
4. Analyze the cost effectiveness of using Smart Paper Technology and fully digitalised approaches over the paper based HMIS for managing health information in Uganda.
5. Assess the impact on the budget after adopting Smart Paper Technology or fully digitalised approaches for managing health information with a focus to community health information systems in Uganda.
6. Evaluate the scalability of the Smart Paper Technology and fully digitalised approaches considering geographic scale and integration with other HMIS components

Uganda 2022-11-01 18:27:02 2025-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Okee Margaret Jill
ID:
USING INFORMATION AND COMMUNICATION TECHNOLOGY FOR LEARNING ENHANCEMENT IN HIGHER EDUCATION INSTITUTIONS: CASE OF KAMPALA METROPOLITAN AREA
REFNo: SIR144ES

1.To determine the relationship between e-learning pedagogy and learning enhancement.
2.To determine the relationship between motivation of students and learning enhancement.
3.To determine the relationship between ICT systems characteristics and learning enhancement.
4.To determine the combined effects of the relations of e-learning pedagogy and ICT systems characteristics on motivation of students.
5.To determine the combined effects of the relationships of e-learning pedagogy, motivation of students and ICT characteristics on learning enhancement.
6.To establish the intermediating role of the e-learning policy between institutional support and learning enhancement.
Uganda 2022-10-31 15:34:11 2025-10-31 Engineering and Technology Non-Clinical Trial Degree Award
Charles Drago Kato Drago
ID: UNCST-2021-R012897
Development and evaluation of a community-based bat-human interface monitoring program for zoonotic spillover early warning and response in Uganda
REFNo: HS2428ES

1) To build a community-created map of bat-human interfaces in Bundibugyo.
2) Establish an ecological baseline on the bats and human- bat interactions in Bundibugyo district
3) Establishing a sustainable bat-human interface monitoring program
Uganda 2022-10-31 15:31:18 2025-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dr. Betty Kwagala
ID: UNCST-2022-R009048
Economic and Health impact and the resilience of last mile populations in artisanal and small- scale mining unplanned settlements in Sub-Saharan Africa before, during and after COVID-19: The case of Ghana and Uganda
REFNo: SS1496ES

4) To identify, co-develop and pilot test one context specific priority intervention to strengthen last mile adolescent girls’ resilience during future crises,3) To describe the interventions proposed by these populations and literature for strengthening adolescent girls’ coping skills and fostering resilience during the COVID-19 pandemic recovery and their applicability to future crises,2) To identify the coping mechanisms adolescent girls used to support their health and economic wellbeing during the pandemic.,1) To assess the economic and health impacts of the COVID-19 pandemic on the last-mile adolescent girls living in unplanned mining communities in Uganda and Ghana. To describe and assess the economic, health impacts and the resilience of adolescent girls in unplanned mining communities and coping mechanisms during the COVID-19 pandemic to support their future resilience and ability to cope during recovery and in similar future crises.
Uganda 2022-10-28 15:09:30 2025-10-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
A randomized, double-blind, positive-controlled Phase III clinical trial to evaluate the efficacy and safety of SCTV01E (A COVID-19 Alpha/Beta/Delta/Omicron Variants S-Trimer Vaccine) in population previously unvaccinated with COVID-19 vaccine and aged ≥18 years
REFNo: HS2508ES

To evaluate the protective efficacy of SCTV01E against symptomatic COVID-19 occurring from 14 days after the 2nd dose in population
previously unvaccinated with COVID-19 vaccine.


To evaluate the protective efficacy of SCTV01E against symptomatic COVID-19 occurring from 7 days after the 3rd dose in population previously unvaccinated with COVID-19 vaccine
Uganda 2022-10-28 15:05:42 2025-10-28 Medical and Health Sciences Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
ASSESSMENT OF NEURAL TUBE DEFECTS AMONG NEWBORNS IN UGANDA: A STUDY OF PREVALENCE, RISK FACTORS, AND THE ROLE OF GENE-ENVIRONMENTAL INTERACTIONS (NTDS IN UGANDA)
REFNo: HS2479ES

Determine the proportion of newborns with neural tube defects.
2. Assess the correlation of common NTD risk factors in the development of NTDs.
3. Evaluate the environmental-gene interactions in the development of NTDs.

Uganda 2022-10-28 13:30:38 2025-10-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
AMC-104, Feasibility study of ocular surface squamous neoplasia (OSSN) surgical excision in people living with HIV in sub-Saharan Africa (SSA)
REFNo: HS2366ES

To assess the feasibility of conducting multi-center prospective studies on surgical excision of suspected OSSN lesions in SSA in people living with HIV/AIDS (PLWHA).,
Uganda 2022-10-28 13:28:27 2025-10-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
Capacitating One Health in Eastern and Southern Africa (COHESA)
REFNo: SS1482ES

To understand One Health performance, capacity, and bottlenecks within Uganda,To understand Current One Health Research and Innovation within Uganda,To understand One Health challenges, gaps and capacities within Uganda,
Uganda 2022-10-27 9:26:54 2025-10-27 Social Science and Humanities Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
MULT-COUNTRY AETIOLOGY OF GENITAL ULCER STUDY
REFNo: HS2498ES

To determine the prevalence of other sexually transmitted infections in individuals with GUD,To assess the Aetiology of genital ulcer diseases in Low and Middle Income Countries.,
Uganda 2022-10-27 7:52:03 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
STANDARD i-Q COVID-19 Ag Home Test - Laymen study including Usability.
REFNo: HS2511ES

The objective of this laymen study is to establish the usability of the STANDARD i-Q COVID-19 Ag Home Test in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
Uganda 2022-10-27 7:48:55 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
Survey Protocol Zone of Influence Survey Uganda 2022 Feed the Future Phase Two Zone of Influence and Resilience Focus Zone Midline Indicator Assessment
REFNo: A232ES

The Midline Survey will collect primary data to generate estimates for a total of 25 indicators—14 Feed the Future P2-ZOI indicators, plus a new indicator on water security, and 10 RFZ indicators, which will only be collected in the RFZ. ,
Uganda 2022-10-27 7:38:03 2025-10-27 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Experiences of Village Taskforce members and Community Health Workers in COVID-19 prevention and control in Uganda
REFNo: HS2502ES

To assess the experiences of village task force members and community health workers (CHWs) in response to COVID-19 so as to provide information to strengthen community response to the pandemic in Uganda.
Uganda 2022-10-27 7:35:53 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."