Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Barbara Nayebare Baturaine
ID: UNCST-2025-R021900
AN ASSESSMENT TO UNDERSTAND THE DIFFERENT TARGET AUDIENCE NEEDS (INCLUDING THEIR KNOWLEDGE, ATTITUDES, BELIEFS, AND PRACTICES), AND DEVELOP APPROPRIATE BEHAVIOR CHANGE COMMUNICATION AND MARKETING STRATEGIES
REFNo: SS4464ES

The objective of the survey is to carry out a detailed Knowledge, attitude and Practice survey and design of an evidence-based National FMNR Social Marketing and Behavioral Change Communications Strategy (2023-2028). This document is to be used for communication, marketing and implementation of programs to promote socially beneficial behavior change towards the adoption and scale up of FMNR. This will be informed by primary data collection to inform the development of the strategy.
Uganda 2025-11-04 13:44:41 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
VICTORIA NAKAGIMU MWAZI
ID: UNCST-2025-R020484
FOOD ENVIRONMENT, DIETARY PATTERNS AND NUTRITIONAL STATUS OF SECONDARY SCHOOL TEACHERS IN KAMPALA CITY
REFNo: HS6358ES

To assess the food environment of secondary school teachers in Kampala City, Uganda.
(ii) To analyse the food consumption patterns of secondary school teachers in Kampala City, Uganda.
(iii) To assess the nutritional status and associated factors of secondary school teachers in Kampala city.
(iv) To explore the perceptions of stakeholders on the food environment, diet and the nutritional status of secondary school teachers in Kampala City.

Uganda 2025-11-04 13:42:47 2028-11-04 Medical and Health Sciences Non-Clinical Trial Degree Award
Opportuna Kweka Leo
ID: UNCST-2025-R021025
STRENGTHENING KNOWLEDGE, EVIDENCE USE AND LEADERSHIP IN THE GLOBAL SOUTH ON FORCED DISPLACEMENT: WITH A FOCUS ON EAST AFRICA
REFNo: SS4309ES

Conduct research on forced displacement, namely refugees, internally displaced persons and development/conservation/disaster and climate changed induced displacement). (ii) Build capacity on forced displaced issues through seminars, training of masters, PhD and postdoctoral students doing research on forced displacement. (iii) Work with policy makers to discuss the state of the knowledge, constraining factors and possible angles for inclusion of those marginalized. (iv) Work with NGOs to conduct outreach activities either expanding and upscaling existing outreach activities (originating from refugees or external actors) or start new empowerment programmes on social and legal inclusion. (v) Develop a master’s programme on forced displacement, which will be offered in the Department of Geography at the University of Dar es Salaam
Tanzania 2025-11-04 13:40:10 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Alinda
ID: UNCST-2025-R020482
PHYSICAL PLANNING AND URBANIZATION IN UGANDA: A CASE OF FORT PORTAL CITY, CENTRAL DIVISION
REFNo: SS4377ES

General Objective (Purpose) of the Study The study is to evaluate the effect of physical planning on urbanization in Fort Portal City, Uganda. Specific Objectives of the Study i.To assess the effect of Urban Design on urbanisation in Fort Portal City. ii.To examine the influence of Enforcement Mechanism on Urbanisation in Fort Portal City. iii.To evaluate the contribution of Monitoring & Evaluation on urbanisation in Fort Portal
Uganda 2025-11-04 13:37:44 2028-11-04 Social Science and Humanities Non-Clinical Trial Degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Amplifying Community Voices and Lived Experience of the Perceived Impact of Climate Change on Health among Community Health Workers in Namayingo District, Uganda
REFNo: SS4546ES

1.Document CHW experiences of the intersection between climate change and health among individuals, families, and communities.
2.Assess CHW experiences of how climate change affects their role and the health system more broadly.
3.Describe CHW perspectives on community strength and resilience in the face of the climate crisis, including local solutions.
4.Explore CHW recommendations for developing a climate-informed health workforce and climate-resilient health systems and communities.
Uganda 2025-11-04 13:34:31 2028-11-04 Social Science and Humanities Non-Clinical Trial Non-degree Award
Prosper Behumbiize
ID: UNCST-2025-R019986
Uganda’s Digital Mental Health Leap Harnessing DHIS2 for Data-Driven Insights
REFNo: HS6407ES

The project seeks to address Uganda's mental health data quality, access and utilisation gap by leveraging the DHIS2 platform to digitise the depression and anxiety facility data pipeline, from data generation to analysis and insight generation. Primary objectives The specific objectives are; - Create a harmonised, digitised dataset to enable access of individual granular longitudinal mental health data. - Design and deploy an open-access digital tool and dataset repository to ensure transparency, scalability, and ease of access to analytical outputs. - Engage stakeholders in capacity-strengthening activities. Secondary objectives - Conduct secondary data analysis using open-source Artificial Intelligence (AI) and Machine Learning (ML) models to derive actionable insights from standardised datasets. - Generate policy-relevant outputs, including dashboards, open-source publications, and policy briefs, to inform decision-making at various levels.
Uganda 2025-11-04 13:33:24 2028-11-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HOPE KANSIIME
ID: UNCST-2024-R004499
Designing an optimised framework for effective usage and efficient access of Electronic resources in the consortium of Ugandan university libraries
REFNo: SIR561ES

To establish the acceptability and usability of the developed framework designed to enhance the access and usage of e –resources within the consortium of Uganda university libraries,To design and develop an optimised framework aimed at improving the accessibility and utilization of e-resources within the consortium of Uganda university libraries,To determine the necessary prerequisites for creating an optimized framework that will improve the accessibility and utilization of e-resources in the consortium of Uganda university libraries?,To conduct a cross-sectional study to evaluate how E-resources are utilised, examine access patterns and identify barriers and challenges to their usage within the consortium of Uganda university libraries,To optimise Electronic resource utilisation in Ugandan university consortium by developing an efficient access and usage framework,
Uganda 2025-11-04 13:31:17 2028-11-04 Engineering and Technology Non-Clinical Trial Degree Award
Edwin Nuwagira
ID: UNCST-2021-R013488
Improving Diagnostic Strategies for Post-Tuberculosis Lung Disease in Ugandan Primary Health Care Settings (IMPULSE-TB)
REFNo: HS6402ES

To test the feasibility and acceptability of the diagnostic algorithm in facilitating timely post-TB lung diseasediagnosis at primary healthcare facilities,To use qualitative methods to identify barriers and facilitators of diagnosis to post-TB lung disease,To develop, test and validate a clinical algorithm for diagnosing post-TB lung disease based on clinical and sociodemographic characteristics,
Uganda 2025-11-04 13:29:51 2028-11-04 Medical and Health Sciences Non-degree Award
Francis Pebalo Pebolo
ID: UNCST-2022-R010630
Incidence, risk factors and clinical outcomes of neonatal sepsis among HIV-exposed infants of mothers on dolutegravir-based antiretroviral therapy in Uganda
REFNo: HS6486ES

Comparing 28-day clinical outcomes of mothers with HIV on DTG-based ART compared with their HIV negative counterparts.,To compare 28-day clinical outcomes among HIV-exposed neonates of mothers on DTG-based ART and HIV-unexposed neonates.,To compare sepsis incidence risk factors among HIV-exposed neonates of mothers on DTG-based ART and HIV-unexposed neonates,To conduct a scoping review to describe the epidemiology of neonatal sepsis of neonates born to mothers with HIV comparing outcomes on DTG- and non-DTG-containing regimens,
Uganda 2025-11-04 13:00:07 2028-11-04 Medical and Health Sciences Degree Award
ERIC WOBUDEYA
ID: UNCST-2019-R001047
Phase I/II Dose Finding, Safety and Tolerability Study of Daily Rifapentine Combined with Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age with and without HIV
REFNo: HS6555ES

Primary Objectives
Cohort 1 and Cohort 2
• To determine the weight-band dosing of RPT taken as part of the 1HP regimen by evaluating:
⎯ PK RPT exposures among children with and without HIV
⎯ Safety and tolerability of the 1HP regimen among children with HIV while receiving twice-daily DTG and children without HIV through 28 days of dosing
Cohort 2
• To evaluate the effect of RPT taken as part of the 1HP regimen on the PK of DTG
Secondary Objectives
Cohort 1 and Cohort 2
• To evaluate the effect of covariates including age, weight, sex, ethnicity, nutritional status, and HIV-1 status on the PK of RPT taken as part of the 1HP regimen
• To evaluate the safety of the 1HP regimen through 24 weeks of follow-up
• To evaluate the palatability and acceptability of the 1HP regimen
• To evaluate adherence to the 1HP regimen
Cohort 2
• To evaluate the safety and tolerability of twice-daily DTG through 42 days among children with HIV who are receiving 1HP
• To evaluate virologic control (less than 200 copies/mL) at Day 42 among children taking a DTG-based ARV treatment regimen co-administered with 1HP

Uganda 2025-11-04 12:59:17 2028-11-04 Medical and Health Sciences Clinical Trial Non-degree Award
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