Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Tana Chongsuwat
ID:
Evaluation of Understanding, Perceptions, and Attitudes Toward Cervical Cancer Screening, Prevention, and Treatment Services Available to Women in Gulu City, Uganda
REFNo: HS1862ES

Understand attitudes and perceptions regarding seeking cervical cancer screening, treatment, or prevention services.,Assess the level of knowledge of men and women on cervical cancer etiology, risk factors, screening, and prevention services available to them.,
USA 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R011972
Adaptive immunity to Mtb-infection and TB disease among young Ugandan children”
REFNo: HS1870ES

1.To recruit Ugandan children 5 years and younger (< 60 months), with and without perinatal HIV-exposure and/or infection, who are household contacts of an adult with confirmed TB disease
2.To identify immunologic phenotypes that correlate with TB disease, versus remaining asymptomatic following TB household contact, in young children with and without perinatal HIV-exposure and/or infection
3.To determine if MTB-specific T cell and/or antibody profiles can be used to distinguish TB disease from asymptomatic MTB infection, in young children with and without perinatal HIV-exposure and/or infection
4.To determine how perinatal HIV exposure/infection alters MTB-specific adaptive immune profiles

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Muhindo
ID:
Tackling coronavirus disease-2019 Vaccine Hesitancy among People Living with HIV in Kampala, Uganda
REFNo: HS1902ES

To describe the prevalence and factors associated with COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
2. To explore the drivers of COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
3. To develop and pilot educational materials to promote COVID-19 vaccine uptake among adult PLHIV in Kampala, Uganda

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
Voluntary stool collection for optimizing laboratory techniques at the MRC/UVRI and LSHTM Uganda Research Unit
REFNo: HS1910ES

Objectives of the research project:
• To obtain Schistosoma mansoni ova for training and optimisation of the process of miracidia hatching and snail infection
• To obtain S. mansoni ova for training and optimisation of the process of sex determination of cercariae
• To develop materials such as S. mansoni DNA that can be used as reagents and/or positive controls.
• To make available S. mansoni materials for use in the routine evaluation of proficiency of assays and for the testing of reagents and new assay kits

UK 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE MBABAZI -MPYANGU
ID:
Thriving Together: Creating Social Support Groups for the Reintegration and Empowerment of Formerly Abducted Women in Northern Uganda
REFNo: SS965ES

1) Assess the current social, economic and psychological status of formerly abducted women in Northern Uganda as compared to never abducted comparable women
2) Scientifically test the effectiveness of women’s support groups in facilitating the reintegration of formerly abducted women, raising their aspirations, creating economic opportunities and increasing their overall well-being.
Uganda 2021-12-06 2024-12-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
DEVELOPMENT OF AFFORDABLE, EASY TO USE, AND RAPID POINT OF CARE DIAGNOSTIC TESTING PLATFORMS FOR COVID-19 SUITING REMOTE SETTINGS OF SUB-SAHARAN AFRICA.
REFNo: HS1648ES

1.To optimize and validate reagents (recombinant peptides, monoclonal and polyclonal antibodies)’s performance towards capture of SARS- CoV 2 virus antigen and host specific antibodies
2.To develop prototypes of lateral flow immunochromatography test (LFT) and tube-agglutination test platforms for COVID19 testing
3.To perform In-dependent validation of the developed test platforms.


Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayebazibwe Kakoba Gloria
ID:
Determinants of uptake of Mass Drug Administration for schistosomiasis control in Butiaba, Uganda
REFNo: SS1083ES

1. To determine the uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda 2. To examine socio demographic characteristics associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda. 3. To assess barriers related to knowledge that are associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda. 4. To assess barriers related to attitudes that are associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda
Uganda 2021-12-03 2024-12-03 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Birabwa
ID: UNCST-2021-R012851
INCREASING COVERAGE AND UPTAKE OF VOLUNTARY FAMILY PLANNING IN EMERGENT TOWNS AND CITIES IN UGANDA – THE CASE OF JINJA AND IGANGA
REFNo: HS1826ES

General objective To contribute to the reduction of unmet of unmet need and increased use of VFP in urban settings by adapting high-impact practices in FP and developing and testing a tailored package of interventions to increase coverage and uptake of VFP services in emerging urban areas. The project also aims to contribute to improved performance of urban health systems in the study sites with regard to VFP. Specific objectives Implementation objectives i. To develop and implement a tailored package of high-impact interventions fit for emerging urban settings in Uganda using participatory approaches ii. To improve understanding of FP and decision-making capacity for healthy reproductive or contraceptive behaviors; strengthen effective delivery and management of FP services. Research objectives i. To explore the current coverage of VFP and barriers and facilitators of contraception use in emergent urban settings in eastern Uganda ii. To assess the effectiveness, facilitators and barriers of the proposed intervention package in improving VFP service provision, accessibility and utilization iii. To explore how unintended pregnancies/birth could be associated with child survival and childhood health care in urban settings
Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Arinaitwe
ID:
News Media Presentation Of Basic Education Teachers during the COVID-19 Pandemic: A Content Analysis of the Daily Monitor and the New Vision in Uganda.
REFNo: SS1068ES

1. To examine how teacher story coverage in the The Daily Monitor and The New Vision relates to the frames and themes of the research in the space of May 2020 to August 2020 during the COVID-19 pandemic.
2. To identify the frames of teacher stories in the The Daily Monitor and The New Vision in Uganda between May 2020 to August 2020 during the COVID-19 pandemic.
3. To examine the major themes of teacher stories that were published in the The Daily Monitor and The New Vision in Uganda newsrooms between May 2020 to August 2020 during the COVID-19 pandemic.
Uganda 2021-12-03 2024-12-03 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
Low-interventional, multi-centre study of the burden of nosocomial infections among hospitalised patients in sub-Saharan Africa
REFNo: HS1880ES

Aim:
To assess antimicrobial resistance rates, as well as clinical outcomes (including treatment outcomes, mortality rate, hospital length of stay), healthcare resource utilisation (HCRU) and associated costs among hospitalised patients with nosocomial infections at Mulago Specialised Referral Hospital.

Study Objectives:
1. To estimate the prevalence of resistance in nosocomial infections(NI) amongst patients hospitalized at Mulago Specialized Referral Hospital
2. To describe treatment outcomes amongst hospitalized patients with NI, at the end of therapy and at hospital discharge
3. To assess mortality rates (all-cause & infection-related) of hospitalized patients with NI, at the end of therapy & at hospital discharge
4. To assess hospital length of stay amongst hospitalized patients with NI.

Secondary Study Objectives
1. To describe treatment outcomes amongst hospitalized patients with NI at Day 14/30 post-treatment initiation
2. To assess mortality rates (all-cause and infection-related) of hospitalized patients with NI, at Day 14/30 post-treatment initiation
3. To assess ICU length of stay amongst hospitalized patients with NI.
4. To describe the characteristics of hospitals participating in the study
5. To assess HCRU and associated costs post-hospitalization amongst hospitalized patients with NI
6. To assess the nursing care demand amongst hospitalized patients with NI

Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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