Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Winnie  Muyindike R
ID: UNCST-2021-R013558
TB Risk by Alcohol Consumption
REFNo: HS1962ES

To determine the incidence of active TB disease among PLWH with prior LTBI, who received TPT, by level of alcohol use. To estimate the incidence rate of new TB infection among PLWH with prior negative TST results by level of alcohol use. To examine the risk of acquiring TB infection and of incident active TB disease among PLWH with heavy alcohol use after receipt of TPT in PLWH in Uganda.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
Landscape Analysis of Health Technology Assessment (HTA) Ecosystem in Uganda.
REFNo: HS1935ES

The main objective of the landscape assessment is to understand the current decision-making environment in Uganda’s health sector relevant to priority setting, including the identification of key stakeholders and interests, to support the development of a strategy to institutionalise HTA as an essential process for priority setting and evidence-informed decision making in Uganda’s quest for UHC.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christopher Tumwine
ID:
A QUALITATIVE STUDY OF THE AGRICULTURAL LIVELIHOOD SUPPORT PROGRAMME TO PERSONS LIVING WITH HIV IN UGANDA
REFNo: HS1954ES

To assess whether HIV programmes in Uganda still need to provide livelihoods’ support to persons living with HIV in the era-of test and treat. To examine clients’ perspectives on changes/benefits experienced as a result of participating in the agricultural livelihood support programme. To examine challenges which have been experienced by clients as result of participating in the agricultural livelihood support programme. To examine key stakeholders’ perspectives on the process, benefits and challenges of the agricultural livelihood support programme to HIV clients.
Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Anti-Retroviral Therapy Adherence Measurement Methods and Virological Failure in HIV infected Ugandans on long-term ART
REFNo: HS1949ES

1a. To describe incidence of virological failure in patients enrolled in the long-term ART cohort and assess the relationship between adherence to antiretroviral therapy (ART) measured either by patient self-report, appointment keeping and pill count and having virologic failure among HIV-infected Ugandan adults receiving long-term first line.
1b. To examine overall adherence measurement methods as a predictive test for VF among long term ART patients using a case control design taking patients confirmed with VF as cases and use incidence density sampling to sample for controls matched with time and age.
2. Determine the barriers and facilitators of ART adherence among patients on long-term ART at adult Infectious Diseases Institute (IDI) ART clinic using the Theoretical-Domains-Framework with 16 semi-structured, in-depth interviews with both people experiencing VF and those without VF, and ART providers (Medical Officers, Nurses, and counsellors)

Uganda 2021-12-15 2024-12-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hella Peter Eszter
ID:
The effects of water shortage on female chimpanzee social behaviour in the Budongo Forest Reserve
REFNo: NS278ES

This research examines the space use and social behavior of female chimpanzees in the Budongo Forest Reserve, Uganda. In the forest, there are two habituated chimpanzee communities – Waibira, where habituation started in 2011, and Sonso, where habituation started in 1990. While both groups have high year-round food availability, the Waibira group faces an unusual ecological pressure during the annual dry season, when, despite being a rainforest-dwelling group, all permanent water sources within their home range dry up, with the exception of one waterhole. Describing how the female chimpanzees of the community are affected by this annually recurring water scarcity will help us understand the ecological pressures influencing chimpanzee social and ranging behavior. The project aims to provide a detailed description of the ranging of Waibira females, as well as their association patterns, levels of aggression, and gregariousness, and investigate whether any seasonal changes due to water availability are present. Other aims are to determine the dominance hierarchy of the females of the group, and to investigate whether individual factors influence strategies used to deal with water scarcity, such as increasing daily travel, or consuming more water-rich food.
Hungary 2021-12-13 2024-12-13 Natural Sciences Non-Clinical Trial Degree Award
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
Ethics of Using Digital Adherence Monitoring Technologies to Support Tuberculosis Medication (DATs Ethics Study)
REFNo: HS1692ES

Develop an initial framework for research and implementation of DATs in TB in Uganda, drawing from the ethical opportunities and challenges identified in Aim 1. ,Assess ethical opportunities and challenges associated with experienced DATs (electronic pill bottles, SMS) and emerging DATs (cell phone-based dose reporting, video calls, ingestion sensors) using the Consolidated Framework for Implementation Research. ,
Uganda 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Schwartz William
ID:
A Comprehensive Study of Human-Carnivore Conflict Mitigation and Prevention Measures in Queen Elizabeth National Park’s Unique Context of Human and Large Carnivore Ecology
REFNo: NS309ES

The following management-driven research proposal seeks to investigate human-carnivore conflict challenges in Queen Elizabeth National Park, Uganda through five interdisciplinary and transdisciplinary retro- and prospective studies (conservation sociology, community ecology, ecosystem services, wildlife ecology, and conservation biology) in the hopes of making informed, integrated, and strategic mitigation and prevention efforts. This includes 1) a compound cost-benefit analysis of fencing as a human-carnivore conflict (HCC) prevention and carnivore conservation measure; 2) a critical review of Uganda Carnivore Program’s (UCP) carnivore conflict mitigation and prevention efforts (with special emphasis on safe husbandry, experiential tourism, and compensation of genuine losses); 3) a brief review of large carnivore ecology, its resources needs, and current impacts of anthropogenic activity on large carnivore viability in Queen Elizabeth National Park; 4) competition-strategies and tactics of human ecology with wildlife ecology in Queen Elizabeth National Park and its impacts on ecosystem productivity and services; and 5) a critical cultural context review of local custodianship concepts vis-à-vis integrated management approaches (Resource Sharing Agreements, compensation, livelihood support etc.).
USA 2021-12-13 2024-12-13 Natural Sciences Non-Clinical Trial Degree Award
Eunice Ndirangu-Mugo Wambui
ID:
Understanding and informing the Development of Institutional Strategies for educational Resilience in online teaching and learning for undergraduate nursing and midwifery programs in Pandemic Times in East Africa (U-DISRUPT study)
REFNo: HS1923ES

1. Explore the perceptions of faculty and students towards online teaching and learning due to COVID-19
2. Determine students' and faculty preparedness with the transitioning to online learning during the COVID-19 pandemic
3. To establish the relationship between the online teaching presence, social presence, and cognitive presence among the faculty staff and students with the transitioning to online teaching during the COVID-19 pandemic
4. To assess the effects of the online teaching presence, social presence, and cognitive presence among the students with the transitioning to online teaching during the COVID-19 pandemic
5. Describe how to optimize the quality of online learning for the faculty and students in the university.

Kenya 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HINDRAH AKISIIMIRE
ID:
KNOWLEDGE ACCESS AND SHARING THROUGH CULTURAL ASTRONOMY IN UGANDA’S REFUGEE SETTLEMENTS AND HOST COMMUNITIES.
REFNo: SS1116ES

To facilitate introduction of astronomy to the community of refugees.,To create an avenue of usefulness of institutional cultural astronomy knowledge in areas that may need purchase and use of physical gadgets,To provide a formal structure for knowledge storage and sharing,To catalogue cultural astronomy from refugees who are likely to lose this knowledge due to varying cultures and communities in the settlement camp.,To introduce astronomy to refugee settlements and gather information on the subject from the target communities. The gathered data from this project will be incorporated in a mobile astronomy lab for replication in other regions of Uganda.,
Uganda 2021-12-13 2024-12-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
Sero-prevalence of Severe Acute Respiratory Syndrome Coronavirus-2 antibodies amongst non-vaccinated People Living with HIV attending the Infectious Diseases Institute clinic
REFNo: HS1956ES

General Objective The objective of this study is to determine the seroprevalence of SARS-CoV-2 antibodies in non-vaccinated PLWHIV at high risk. This will generate information on the exposure of the SARS-CoV-2 virus in this population Specific Objectives 1. To determine the seroprevalence of SARS-CoV-2 antibodies amongst non-vaccinated PLWHIV at high risk. 2. To determine risk factors for the seroprevalence of SARS-CoV-2 antibodies amongst non-vaccinated PLWHIV at high risk
Uganda 2021-12-13 2024-12-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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