Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Doris Muhwezi Kakuru
ID:
Centering Marginal Voices: Building Research and Advocacy Skills for Young Mothers to Negotiate for their Sexual and Reproductive Health and Rights
REFNo: SS1114ES

(1)To examine existing policies, programs, and practices that shape adolescent sexual and reproductive health and (in)justice in Uganda;
(2) To assess young mothers’ everyday encounters, struggles, and resistance to the dominant gendered, generational, structural and cultural forces that frame young motherhood and how they negotiate motherhood;
(3) To analyze young mothers’ conceptualization of the gendered social norms that shape their SRH experiences and realities;
(4) To describe the process of co-creating youth-focused, contextually relevant knowledge required for young mothers’ SRH justice;
(5) To analyze public response to young people’s engagement in research, advocacy and conversations about young motherhood.

Uganda 2022-01-19 2025-01-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gideon Ariong
ID:
REC.00.647.01:Household Vulnerability to Food Insecurity and Coping Strategies: The Case of Smallholder Farmers affected by Fall armyworm (Spodoptera frugiperda) Invasion in Eastern Uganda
REFNo: A173ES

To examine the status of households' food insecurity among the smallholder maize farmers affected by fall armyworm in Ngora district
To analyze the households' vulnerability to food insecurity among smallholder maize farmers affected by fall armyworm in Ngora district
To determine the household food security coping strategies among smallholder maize farmers affected by fall armyworm in Ngira district
Uganda 2022-01-19 2025-01-19 Agricultural Sciences Non-Clinical Trial Degree Award
ROSCO KASUJJA
ID: UNCST-2019-R000504
STEPPED-WEDGE CLUSTER RANDOMIZED CONTROLLED TRIAL OF THE PROACTIVE COMMUNITY CASE DETECTION TOOL FOR CHILDREN AGED 6-18 YEARS IN NEED OF MENTAL HEALTHCARE SERVICES IN NORTHERN AND WESTERN UGANDA
REFNo: HS1955ES

The primary objective is to examine whether the CCDT is effective in increasing utilization of TPO’s mental healthcare services among children and adolescents after introducing pro-active case detection using the CCDT as compared to practice-as-usual.,
Uganda 2022-01-18 2025-01-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gregory Klazura J
ID:
Pediatric Surgery Training for Rural Ugandan Providers: An Evaluation and Quality Improvement Study
REFNo: HS1895ES

Evaluate the impact of the Pediatric Emergency Surgery Course on rural healthcare providers.
Objective 1: Measure knowledge retention for past course participants.
Objective 2: Measure provider knowledge before and after the course for new participants.
Objective 3: Evaluate course surveys to determine areas for course improvement.
Evaluate the impact of the Pediatric Emergency Surgery Course on pediatric surgical patients.
Objective 4: Measure pediatric operative volume at rural hospitals where the course was delivered before and after the course.
Objective 5: Measure complication rates (mortality, readmission, surgical site infection, reoperation) of patients treated or referred by providers at one of the designated sites before and after the course.
Objective 6: Measure the volume and time to referral of complex pediatric surgical conditions for patients who were treated at one of the designated sites before and after the course.

USA 2022-01-18 2025-01-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
PHARMACOKINETICS OF DRUGS USED TO TREAT DRUG SENSITIVE-TUBERCULOSIS IN BREASTFEEDING MOTHER-INFANT PAIRS: AN OBSERVATIONAL PHARMACOKINETIC STUDY
REFNo: HS1948ES

To define transfer of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol to the breastfed infant.
To determine the area under the concentration-time curve (AUC), clearance and volume of distribution of these drugs.

UK 2022-01-18 2025-01-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nicholus Nanyeenya
ID:
Viral Non-Suppression, Drug Resistance, Perceptions and Effectiveness of Intensive Adherence Counselling among People Living With HIV/AIDS on Antiretroviral Therapy with Low-Level Viraemia in Uganda
REFNo: HS2008ES

d) To determine the effectiveness of intensive adherence counselling in achieving a non-detectable viral load in the management of LLV among PLHIV on ART in Uganda (Sub-study Four).,c) To explore the perceptions of low-level viraemia among PLHIV on ART and healthcare providers in Uganda (Sub-study Three).,b) To understand the prevalence of HIV drug resistance among PLHIV on ART with low-level viraemia, highlighting the significant mutations, in Uganda (Sub-study Two).,a) To determine the viral non-suppression trends among PLHIV on ART with low-level viraemia from 2016 to 2020 in Uganda (Sub-study One).,The aim of the study is to determine viral non-suppression trends, HIV drug resistance prevalence, perceptions and effectiveness of intensive adherence counselling among people living with HIV/AIDS on antiretroviral therapy with low-level viraemia in Uganda; to generate information which may guide the review of the HIV consolidated guidelines and the review of the current viral load testing algorithm in the country. ,
Uganda 2022-01-18 2025-01-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Brian Turigye
ID: UNCST-2021-R012569
Determining the Prevalence and Risk Factors Associated with Hepatitis B Infection in Bugoye Sub County, of Kasese District in Western Uganda
REFNo: HS1900ES

1.Estimate the prevalence of hepatitis B infection in Bugoye sub-county. 2.Identify the risk factors associated with hepatitis B infection in Bugoye sub-county. 3.Explore the knowledge of and attitudes towards hepatitis B in Bugoye sub-county
Uganda 2022-01-17 2025-01-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Esther Atukunda Cathyln
ID: UNCST-2019-R001701
SHINE - Exploring Intersectional Stigmas Among Men Living with HIV in Uganda
REFNo: HS1964ES

The primary objective in this study is to explore experiences of intersectional stigma among MWH and their partners who have unmet reproductive goals.
Uganda 2022-01-17 2025-01-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Children’s Air Pollution Profiles in Africa (CAPPA)
REFNo: HS1695ES

• To collect personal air pollution exposure data, activity profiles, and lung function measurements from a total of 420 children with asthma symptoms aged between 12 and 16 years in 7 African cities.
• To analyse personal air pollution data for exposure patterns and peak exposures, and to compare air pollution as well as activity profiles of children in relation to their socioeconomic and geographical backgrounds both within and between countries and compare with measured data from school-age children in London
• To explore potentially detrimental effects of air pollution, and feasibility of mitigation strategies in children with asthma symptoms.


Uganda 2022-01-14 2025-01-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kirsten Beyer M
ID: UNCST-2021-R013472
Exploring the impact of COVID-19 on cancer prevention and control service delivery in Uganda
REFNo: SS1098ES

The proposed study seeks to explore how COVID-19 has impacted cancer prevention and control activities and COVID-19 vaccination access and distribution in Uganda across the cancer continuum. 1. Investigate health care professionals’ perceptions regarding: a. How COVID-19 has impacted the provision and use of cancer treatment and preventive services. b. Their own personal fears about COVID-19, and fears and misconceptions they’ve encountered among their patients relating to COVID-19 impacting prognosis c. COVID-19 vaccination and its accessibility, coverage and distribution to cancer patients d. The impact of COVID-19 on data collection and analysis activities that support cancer prevention and control 2. Investigate patients’ perceptions regarding: a. How COVID-19 has impacted the provision and use of cancer treatment and preventive services b. COVID-19 vaccination access and distribution to cancer patients c. Fears about how COVID-19 impacts their cancer diagnosis and prognosis
USA 2022-01-14 2025-01-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
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