Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Paul  Kutyabami
ID: UNCST-2020-R015029
An Evaluation of Perceptions and Effectiveness of the Ethical Review Process at Makerere University: A pilot Evaluation at the School of Health Sciences Research and Ethics Committee
REFNo: HS5322ES

1. Assess the perceptions of researchers (from the departments of pharmacy, nursing, dentistry, staff at Makerere University and researchers outside the institution) regarding MaKSHSREC’s ethical review process.
2. To assess the level of satisfaction among researchers on the existing MaKSHSREC ethical review processes.
3. Assess the efficiency and effectiveness of MaKSHSREC ethical review processes.
4. Explore the challenges and areas for improvement in the current MaKSHSREC ethical review processes.

Uganda 2024-12-23 11:38:43 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PAULA KWOREKWA
ID: UNCST-2024-R005035
Assessing the Impact of COVID-19 on the Knowledge, Attitude, and Practice of Medical Waste Management among Waste Handlers at Luweero General Hospital
REFNo: HS5350ES

Main Objective:
To investigate the impact of COVID-19 on the Knowledge, attitude, and practice of medical waste management among waste handlers at Luweero General Hospital.
Specific Objectives:
1. To determine the knowledge of medical waste handlers in recommended waste management practices following the COVID-19 pandemic.
2. To investigate the attitude of medical waste handlers towards practicing the recommendations for proper Medical Waste Management in the post COVID-19 pandemic era.
3. To compare the practices for medical waste management before and after the COVID-19 pandemic.


Uganda 2024-12-23 11:37:27 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Aziku
ID: UNCST-2023-R007595
Baseline Study for Safe and Inclusive Cities Project -Uganda.
REFNo: SS3476ES

To evaluate the achievement of the programme’s intended outcomes, integrating qualitative insights and quantitative data on change in outcome indicators over time (from endline to end-line).

Identify and validate good practices, learnings, and examples of innovation on gender transformative programming.

To generate practical recommendations related to the programme outcomes and the approaches to inform future programming.
Uganda 2024-12-23 11:36:17 2027-12-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rebecca Nansubuga Kaaya
ID: UNCST-2024-R002104
Piloting a frugally innovated surgical fracture table in Uganda: Assessing its functionality, usability, and acceptability.
REFNo: SIR454ES

To pilot a frugally innovated surgical fracture table in Uganda and assess its functionality, usability, and acceptability in resource-limited healthcare settings through:
1. To evaluate the functionality of the frugally innovated surgical fracture table selected healthcare professionals by assessing its ability to: securely position patients, allow for stable positioning and smooth adjustment of the tentative limb position.
2. To assess the usability of the surgical fracture table selected healthcare professionals by measuring: the time required for set-up, the perceived ease of use of the table, the perceived comfort levels during manipulation.
3. To determine the acceptability of the surgical fracture table among selected healthcare professionals by assessing: their overall satisfaction with the table's design, functionality, and usability, willingness to recommend or use the table in their clinical practice and their perceptions of the table's potential impact on patient outcomes and safety

Uganda 2024-12-23 11:35:30 2027-12-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Afiz Kibuuka Kibuuka
ID: UNCST-2021-R012755
A phase III, Multicenter, Randomized, Placebo Controlled, Double blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Frequent Vaso-Occlusive Crises
REFNo: HS5365ES

To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of VOCs* that are healthcare professional (HCP)-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) over the planned 52-week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in 12 months prior to the screening visit).
To compare the efficacy of 5 mg/kg of crizanlizumab versus placebo, with or without hydroxyurea/hydroxycarbamide, on the annualized rate of all VOCs including VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) and VOCs that are self-managed without recommendations from HCP during the event over the planned 52 week treatment period in SCD patients aged 12 years and older with a history of frequent VOCs (4-12 events in the 12 months prior to the Screeening visit
To evaluate the annualized rate of VOCs by type of management between treatment arms over the planned 52-week treatment period: • VOCs that are HCP-managed at a health care facility • VOCs that are HCP-managed via remote consultation • VOCs that are self-managed without recommendations from HCP during the event • VOCs that are HCP-managed via remote consultation or self-managed without recommendations from HCP during the event
To evaluate the time to first VOC that is HCP managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
To evaluate the proportion of participants free from VOCs that are HCP-managed (including VOCs leading to management at a health care facility or those managed via remote consultation) between treatment arms over the planned 52-week treatment period.
Uganda 2024-12-23 11:34:49 2027-12-23 Medical and Health Sciences Clinical Trial Non-degree Award
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