JOYCE NAMWASE
ID: UNCST-2024-R005002
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FEASIBILITY AND EFFECTIVENESS OF A TRAINING INTERVENTION FOR INFORMAL CAREGIVERS OF PEOPLE LIVING WITH DEMENTIA IN RURAL UGANDA (FETIC-DU)
REFNo: HS5165ES
3. To evaluate the feasibility and effectiveness of the training program in improving knowledge and skills of informal care givers for persons with dementia in rural Uganda. 1.4 Research questions
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Uganda |
2024-12-23 12:04:08 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Daniel Murokora Murokora
ID: UNCST-2024-R002689
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Outcomes Evaluation of Reproductive, Maternal and Newborn Care Interventions Implemented by BAMA in Uganda
REFNo: HS5155ES
General Objective
To evaluate the outcomes of Reproductive, Maternal and Newborn Care interventions at BAMA Supported Sites in Uganda.
Specific Objectives
1. To evaluate the impact of NMH interventions on IMMR and IPMR since 2015
2. To explore factors influencing mortality trends since 2015
3. To document the optimum package of MNH interventions that impacted MMR and PMR
4. To assess the impact of BAMA interventions on HPV vaccination uptake for out-of-school girls as well general population (women aged 25-49) cervical cancer screening and linkage to appropriate services
5. To assess the effect of BAMA project interventions on infant development outcomes and adolescent mother’s physical, social, and mental wellbeing outcomes
6. To determine the feasibility and sustainability of MRP
7. To assess the impact of the implementation of MPS transport solution on MNH outcomes
8. To assess the design and impact of the mentor midwives model on MNH outcomes
9. To determine optimum mentorship package and its impact on quality of care and clinical outcomes
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Uganda |
2024-12-23 12:03:10 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
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Faecal exposure behaviours, risk profiles, and predicted efficacy of Water Sanitation and Hygiene interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings
REFNo: HS5190ES
4. To predict the efficacy of suggested interventions on reducing faecal exposure in the private domain in Imvepi and Cox’s Bazar refugee settings (Study IV),3. To determine the factors associated with faecal exposure among children and adults in Imvepi and Cox’s Bazar refugee settings (Study III),2. To determine the faecal exposure risk profile of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study II),1. To explore faecal exposure behaviours and pathways of children and adults in the private and public domain of Imvepi and Cox’s Bazar refugee settings (Study I),To establish the faecal exposure profiles and associated factors in the private and public domain and predict the efficacy of suggested interventions in Imvepi, Uganda and Cox’s Bazar, Bangladesh refugee settings so as to guide exposure reduction interventions.,
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Uganda |
2024-12-23 12:01:21 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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DANIEL BUGEMBE LULE
ID: UNCST-2024-R015332
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DEVELOPMENT OF NOVEL APPROACHES FOR HIV DRUG
RESISTANCE DETECTION USING NANOPORE SEQUENCING TECHNOLOGY
REFNo: HS5352ES
Objectives and Hypothesis
Primary Objective
To develop an end-to-end nanopore NGS workflow for the routine clinical detection of HIV drug
resistance (HIVDR).
Secondary Objective
To compare the HIVDR scoring between Sanger and Nanopore sequencing method of matched samples
to evaluate their concordance for detecting drug resistance mutations.
Exploratory Objectives
1. To develop a method for PCR amplification of low plasma viral load samples, genotype these
with the nanopore method and derive HIVDR mutations.
2. To identify improvements to the nanopore base-calling algorithms that may obviate high error
rates.
3. Provide an expeditious end-to-end analysis pipeline for analysis of HIVDR of Nanopore generated
sequences.
4. To establish if the various base-calling errors of the Nanopore sequencing are occurring in a
stochastic or non-stochastic manner.
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Uganda |
2024-12-23 11:59:00 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Edgar Mulogo Mugema
ID: UNCST-2023-R008170
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Identifying Barriers to Infection Prevention & Control Guideline Adherence in Western Uganda.
REFNo: HS5360ES
Primary Objectives
The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in IPC knowledge amongst HCP and how they may relate to IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts.
Specific Aims
AIM 1: Evaluate adherence to national IPC guidelines across a variety of healthcare facility levels in Western Uganda via a standardized observation protocol through facility-level evaluations.
1A. Guided by Uganda’s national IPC best practices for healthcare facilities and a standardized facility-level checklist adopted from the World Health Organization, we will perform observations of the facility’s physical characteristics, healthcare supplies, and healthcare personnel workflow, including observations of hand hygiene adherence with a standardized checklist.
AIM 2: Assess IPC knowledge, attitudes, and practices of healthcare personnel at multiple levels of Uganda’s national healthcare system, identifying primary barriers to National IPC Guideline adherence.
2A. Healthcare Personnel Surveys: Surveys will consist of both qualitative and quantitative elements to ascertain information on their awareness of foundational IPC concepts within national guidelines, circumscribe a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes that may prevent rigorous adherence to IPC guidelines.
2B. Healthcare Personnel Focus Group Discussions: Focus group discussions will be oriented in such a manner as to ascertain common themes and information on awareness of foundational IPC concepts, gain a perspective on the experience of IPC practices across a variety of facility levels and HCP roles, and understand what limitations are experienced by HCP during their daily patient care-oriented activities. Through these discussions, we hope to gain a working understanding of the implementation of IPC measures across different healthcare facility settings before and after the COVID-19 pandemic, and determine health facility-level attributes, gaps in IPC education and/or training, and HCP workflow concerns that may prevent rigorous adherence to IPC guidelines.
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Uganda |
2024-12-23 11:57:43 |
2027-12-23 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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