Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Musa Sekikubo
ID: UNCST-2021-R014010
A placebo controlled clinical trial investigating the safety and immunogenicity of GBS6 in pregnant women with and without human immunodeficiency virus (HIV) infection and their infants
REFNo: HS1991ES

1. To describe the safety and tolerability of GBS6 when administered at ? 27 0/7 to ? 35 6/7 weeks’ gestation to pregnant women, with and without HIV, aged ? 18 to ? 40 years of age and their infants..
2. To assess the safety of GBS6 in infants born to HIV positive and negative women who were vaccinated during pregnancy.

Uganda 2022-02-11 2025-02-11 Medical and Health Sciences Clinical Trial Non-degree Award
Aisha Nanyiti
ID: UNCST-2021-R013489
A Randomized Control Trial (RCT) on the Adoption of Liquefied Petroleum Gas (LPG) Cooking Technology among Fast Food (Chapati) Vendors in Uganda
REFNo: SS1017ES

This study seeks to establish the impact of hire purchase schemes and health and safety information on adoption of LPG cookstoves by chapati vendors.

This study will achieve the following specific objectives:
1) The impact of learning from LPG use in grace period before purchase armotisation on adoption of LPG cookstoves by chapati vendors for their businesses and households.
2) The impact of hire purchase on adoption of LPG cookstoves by chapati vendors for their businesses and households.
3) The impact of information on safety and health benefits of LPG on adoption of LPG cookstoves by chapati vendors for their businesses and households.
4) The impact of peer learning from other vendors using LPG cookstoves on adoption of LPG cookstoves by chapati vendors for their businesses and households.
Uganda 2022-02-10 2025-02-10 Social Science and Humanities Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Effectiveness of a community health worker delivered care intervention for hypertension control in Uganda: a stepped wedge, cluster randomized control trial.
REFNo: HS1917ES

To assess the effectiveness of a CHW-delivered intervention for hypertension control in Uganda.,
Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Clinical Trial Non-degree Award
Abner Tagoola
ID: UNCST-2021-R013446
Acute Pediatric Critical Illness in Resource-Limited Settings: A Novel Point Prevalence Study
REFNo: HS1968ES

To undertake a prospective, observational, multicenter, multinational point prevalence study to measure the burden of acute pediatric illnesses in low and middle income countries. ,To determine the current resources available to provide acute critical care across low and middle income countries.,To determine hospital resource utilization by children with acute critical illness ,To measure hospital outcomes (hospital mortality, length of stay) in children with acute critical illness in resource-limited settings.,To determine the etiology and prevalence of pediatric acute critical illness amongst children presenting to participating hospitals in resource-limited settings.,
Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Abel Wilson Walekhwa Wilson
ID: UNCST-2021-R011571
Ecological niche modelling for Rift Valley Fever Disease Transmission in selected districts in Uganda
REFNo: HS2019ES

1.To describe the epidemiological characteristics of RVF outbreaks in Uganda for 2013-2021
2.To Profile the clinical presentation of previous RVF cases at farm level
3.To build the epidemiological Livestock network predictive model for RVF outbreaks
4.To build an ecological niche model for next RVF outbreaks in Uganda
5.To build a model for a one health cost effective intervention suitable for Uganda in mitigating RVF outbreaks.
6.To build a cost benefit Analysis for introduction of RVF vaccination programme in Uganda

Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Christopher Udry
ID:
Seeding Innovation through Reality TV
REFNo: A178ES

he project will improve our understanding of farmers’ learning and adoption process by studying the role of information provided to urban and rural network members. Given the low marginal costs of distribution, programs like SSU have a high potential to deliver agricultural advisory services at scale.,to understand if reality TV can help to enhance the knowledge and adoption of recommended agricultural practices among farmers in Uganda.,
USA 2022-02-10 2025-02-10 Agricultural Sciences Non-Clinical Trial Non-degree Award
ALEX KAYONGO
ID: UNCST-2019-R001641
Airway Microbiome and Th17-mediated inflammation in COPD among HIV-infected individuals in a rural Ugandan cohort ACRONYM: HIV-LUNG MICROBIOME (HLM) study
REFNo: HS2035ES

Study aim:
To investigate airway microbiome-driven Th17 mediated inflammation in COPD among HIV-infected individuals

Specific objectives
1. To establish a relationship between airway microbiome and Th17/Treg cellular phenotypes among HIV-infected individuals with COPD.

2. To investigate bacterial mediated Th17 up-regulation of pro-inflammatory genes among HIV-infected individuals with COPD.

3. To investigate the role of bacterial outer membrane vesicles (OMVs) in mediating dysbiosis driven Th17 immune responses among HIV individuals.

Uganda 2022-02-10 2025-02-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SAFINA MUTUMBA NA
ID:
SCHOOL-COMMUNITY PARTNERSHIPS AND IMPLEMENTATION OF INTEGRATED EARLY CHILDHOOD CARE EDUCATION SERVICES IN PRE-PRIMARY SCHOOLS IN KIRA MUNICIPALITY, WAKISO DISTRICT
REFNo: SS1104ES

3. To assess the relationship between School-Service Providers Collaboration and Health Care Practices. ,2. To investigate the contribution of School-Local Leaders Collaboration on the strength of Protection Policies. ,1. To establish the influence of School-Parents Engagement on Stimulation Activities.,
Uganda 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Degree Award
Adam Branch
ID:
Fuelling Violence to Fuelling Peace: Charcoal and Environmental Justice in East Africa
REFNo: SS1157ES

Primary Research Objective: To determine how charcoal can contribute to sustainable peace instead of social and environmental harm. Secondary Research Objectives: Determining the power structures in the charcoal sector. Determining what charcoal extraction practices are used, and what their impact upon ecosystems is. Mapping the relations between communities and charcoal landscapes. Discerning the new pathways to environmental justice that are emerging among communities.
USA 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gilberto Borri
ID:
Mobility, Migrations and Refugees in East Africa:The Case of Uganda.
REFNo: SS1160ES

The research project aims to analyse the multifaceted dynamics of mobility and migration in East Africa with a focus on Uganda.

Specifically, we propose to concentrate on the following topics:

1 – To analyse mobility and migration patterns in relation to Ugandan contemporary models of hospitality from historical, socio-anthropological and gender responsive perspectives

2 – To explore the socio-economic relations between refugees, migrants and hosting communities

3 – To analyse the environmental impact of refugees and migrants on local contexts

4 – To analyse the co-relation between humanitarian development programs on refugees and host communities

5 – To analyse the importance of religions and the diversity of health care systems among refugee and migrant communities
Italy 2022-02-08 2025-02-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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