Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,902
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Determining the Risk of Rheumatic Heart Disease Following Prophylaxis Discontinuation (GOAL-Keep)
REFNo: HS6310ES

Aim 1: Determine the risk of developing moderate/severe rheumatic heart disease (RHD) up to 3 years after Secondary antibiotic propylaxis (SAP) discontinuation among children and adolescents with mild RHD, who have shown echocardiographic stability for at least 2 years on SAP.
Aim 2: Determine the risk of developing moderate/severe RHD up to 6 years after SAP discontinuation among children and adolescents originally with mild RHD, who have shown echocardiographic normalization.

Uganda 2025-08-18 13:25:57 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
Cultural adaptation of the coordinated specialty care (NAVIGATE) in Uganda
REFNo: HS6280ES

Study objective: The study objectives will include

Objective 1. Culturally adapting and locally contextualizing NAVIGATE into a CSC manual (NAVIGATE-UG) for use in Uganda.

Objective 2: Documenting the feasibility and acceptability of using the adapted NAVIGATE-UG manual

Uganda 2025-08-18 13:24:11 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Sainge Nsanyi
ID: UNCST-2025-R019399
Cloud immersion and the future of tropical montane forests (CLOUDFOR)
REFNo: NS991ES

This project aims to quantify water input, tree growth and future species distribution models in the Bwindi Impenetrable Forest National Park, Uganda with three main objectives:
1) To determine the importance of cloud immersion for maintaining annual water inputs and tree growth,
2) To quantify the consequences of future changes in cloud immersion for carbon stocks and fluxes,
3) To assess how different dominant tree species respond to changes in cloud immersion.

Cameroon 2025-08-18 13:22:39 2028-08-18 Natural Sciences Non-Clinical Trial Non-degree Award
PATRICIA NAKASI
ID: UNCST-2022-R009767
Prevalence, Symptoms and Baseline characteristics across Menopausal Stages in Women Living with HIV: A cross-sectional study in Uganda.
REFNo: HS6289ES

Objective 1: To describe the prevalence of premenopause, perimenopause and postmenopause among WLHIV aged 35-60years Objective 2: To describe the menopause symptoms experienced by WLHIV Objective 3: To compare the baseline characteristics across menopausal stages in WLHIV
Uganda 2025-08-18 13:20:32 2028-08-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Semitala Fred
ID: UNCST-2020-R014202
3HP Self-Administered Therapy Strategy, Cluster Randomized Trial (Year 1):Formative Research Study
REFNo: HS6228ES

Aim 1: To collect data on site and patient characteristics to inform stratified randomization with restriction.
Aim 2: To collect patient-level, routinely collected demographic, clinical, and outcome data from clinic registers to establish baseline 3HP initiation and completion rates.

Uganda 2025-08-18 13:19:26 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phionah  Ssemambo Kibalama
ID: UNCST-2025-R018119
COMPASS: Community Perspectives and Behavior Change Strategies for Integrated Long-Acting Reversible Contraception and Long-Acting Injectable PrEP Roll Out for Adolescent Girls and Young Women in Uganda
REFNo: HS6232ES

The overall objective of this study is to enhance the adoption and utilization of integrated LARC and LAI-PrEP services among AGYW in Uganda by understanding their preferences, willingness to use these services, and the influencing perceptions, practices, and norms of key stakeholders.

Primary objectives:
1. Determine preferences and willingness to use LARC and LAI-PrEP by AGYW in Uganda.
2. Characterize stakeholder perceptions, practices, and norms that may influence the adoption of integrated LARC and LAI-PrEP services for AGYW, using the Capability, Opportunity, and Motivation-Behavior (COM-B) model to identify facilitators and barriers, alongside the Behavior Change Wheel (BCW) to develop targeted behavior change strategies.

Uganda 2025-08-18 13:06:49 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kazibwe Herman
ID: UNCST-2025-R017099
IDENTIFICATION OF MINIMAL DATA ELEMENTS FOR PHYSIOTHERAPY OF TRAUMATIC BRAIN INJURY PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL AND MULAGO NATIONAL REFERRAL HOSPITAL
REFNo: HS6201ES

Research Question: What minimal data elements related to physiotherapy are acceptable and feasible for addition into a TBI database maintained at national & regional hospitals in Uganda? Objectives 1.To identify the minimal rehabilitation data elements, informed by international TBI databases, that are appropriate to propose for addition to the current TBI database at two Ugandan hospitals: Mulago National Referral Hospital(MNRH), and Mbarara Regional Referral Hospital (MRRH). 2.To retrospectively assess data quality in medical documentation for each element at MNRH and MRRH. 3.To identify user perspectives of barriers and facilitators to consistent data collection of the identified and proposed data elements across both MNRH and MRRH.
Uganda 2025-08-18 13:05:10 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Mutumba
ID: UNCST-2025-R019247
CHARACTERIZATION OF INCONCLUSIVE SAMPLES ACCORDING TO RAPID TEST FOR RECENT INFECTION (RTRI) IN UGANDA
REFNo: HS6130ES

Main objective of the study is to determine the status of inconclusive samples tested in the field for HIV-1 recent infection.
Specific objectives
1.To perform additional characterization on field tested samples where RTRI results are discrepant with the national HIV testing algorithm (i.e., RTRI “Inconclusive”) to understand patterns or reasons for discrepant results.
2.To identify potential sources of testing errors to help improve quality of recency testing.
3.To compare Asante field tested results with results of the national HIV testing algorithm for RTRI Inconclusive samples

Uganda 2025-08-18 12:55:05 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WINFRED NANNOZI
ID: UNCST-2024-R004301
PREVALENCE AND FACTORS ASSOCIATED WITH TOMOPHOBIA AMONG PRE-OPERATIVE PATIENTS AT KYABIRYA SURGICAL CENTER, BUDONDO SUB-COUNTY, JINJA CITY
REFNo: HS5857ES

To establish the institutional predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the patient-related predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To determine the prevalence of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,
Uganda 2025-08-18 12:53:37 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ALPHONSINA MUJAWIMANA
ID: UNCST-2024-R015924
PREVALENCE, PATTERNS AND FACTORS ASSOCIATED WITH NEURODEVELOPMENTAL DELAY AMONG YOUNG CHILDREN ATTENDING THE PAEDIATRIC OUT PATIENT DEPARTMENT CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS6113ES

General Objective To determine the prevalence, patterns, and factors associated with Neurodevelopmental Delay among young children attending the Paediatric OPD Clinic at Mbarara Regional Referral Hospital Specific objective 1.To determine the prevalence of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 2.To describe the patterns of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 3.To assess the factors associated with neurodevelopmental delay among children under five years at the paediatric OPD at MRRH
Uganda 2025-08-08 16:28:48 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Edirisa Kibuuka
ID: UNCST-2025-R016973
Improving care and support of children with Cerebral palsy: Feasibility and Acceptability of Family care-group model in Kawempe division, Uganda
REFNo: HS6115ES

To evaluate coverage, appropriateness, adoption, acceptability, feasibility, fidelity and costs of implementing CP-family care-group model in improving supportive care of children with CP in peri-urban communities of Kawempe division,To assess perceived barriers and facilitators to implementing CP-family care-group model in improving care and support of children with CP at community, facility and division. ,We intend to roll-out cerebral palsy family care-group model in selected health facility catchment areas to reduce stigma/discrimination and improve supportive care of CP children in Kawempe division,
Uganda 2025-08-08 16:27:42 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Lomonyang
ID: UNCST-2025-R017018
Prevalence of perceived stigma and associated factors among patients with tuberculosis (TB). A cross-sectional study in Napak district, Karamoja region, Uganda.
REFNo: HS6105ES

Overall Objective: To determine the prevalence of perceived stigma and associated factors among patients with tuberculosis in Napak district, Karamoja region, Uganda. Specific Objective 1: To determine the prevalence of perceived stigma among patients with tuberculosis in Napak District. Specific Objective 2: To identify the factors associated with perceived TB stigma among patients with tuberculosis in Napak District.
Uganda 2025-08-08 16:26:22 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ESTHER NANSAMBA
ID: UNCST-2024-R002776
SUCCESSION PLANNING PRACTICES, ORGANIZATIONAL CULTURE AND SURVIVABILITY OF HOTELS IN WESTERN UGANDA
REFNo: SS3479ES

i.To examine the effect of skill development on hotel survivability in western Uganda.
ii.To determine the effect of mentorship on hotel survivability
iii.To establish the effect of internal promotion on hotel survivability in western Uganda
iv.To determine the moderating effect of organizational culture on the relationship between succession planning practices and the survivability of hotels in western Uganda.
v.To determine the level of survivability of hotels in western Uganda.
Uganda 2025-08-08 16:24:31 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Evaluation of a point-of-care molecular diagnostic test for brucellosis
REFNo: HS6127ES

Aim 1. Evaluate a point-of-care, rapid recombinase polymerase amplification, lateral flow detection assay (RPA-LF) for Brucella using clinical specimens from children and adults in rural southwestern Uganda with suspected brucellosis. Aim 1a: Determine the sensitivity, specificity, positive predictive value, and negative predictive value of the RPA-LF assay as compared to the current gold standard, blood culture, and quantitative PCR (qPCR). At Epicentre Uganda Research Laboratory, we will retrospectively perform the RPA-LF test on blood collected from patients presenting to health facilities in the Kazo and Kasese districts with malaria-negative fever for 1 week and one or more of the following symptoms: night sweats, headache, weight loss, fatigue, myalgia or arthralgia, and anorexia. We hypothesize that the RPA-LF assay can be successfully conducted in Uganda in a reference laboratory setting. In addition, we postulate that its sensitivity will be better than that of the currently available qualitative slide agglutination test and blood culture and will match that of qPCR. Aim 2b: Demonstrate the preliminary feasibility of RPA-LF test use at a peripheral health center in rural southwestern Uganda. We will conduct a small pilot sub-study to assess the acceptability and feasibility of test implementation by laboratory technicians at one of the study sites. We hypothesize that the assay can be successfully performed by local laboratory staff with minimal capacity investment. Aim 2: Explore the use of the RPA-LF assay for testing of cow and goat milk. For participants who test positive for brucellosis by slide agglutination test or blood culture, we will test self-collected pooled milk samples from their households using the Brucella Milk Ring Test and the RPA-LF assay and assess concordance between the two diagnostic methods.,The objective of this proposal is to preliminarily validate an RPA-LF assay for brucellosis that can be implemented in rural contexts in LMIC to improve brucellosis diagnosis and management.,
Uganda 2025-08-08 16:22:39 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Musinguzi
ID: UNCST-2025-R017309
Maintenance of Place Attachment and Future Aspirations: Towards a Model through Insights from Marginalised Indigenous Communities in Uganda
REFNo: SS4116ES

The study broadly aims to unravel the different forms of social-symbolic work Indigenous communities acting entrepreneurially (including business operators and owners) engage in to signal their relationship with their ancestral land to restore, preserve, and maintain cultural heritage for their future generation after displacement and their community’s aspirations. To achieve this objective, the study answers the research question below:

How do Indigenous communities act towards restoration, preservation, and maintenance of linkage to their cultural heritage for their future generation after displacement and their communities’ future aspirations?

Uganda 2025-08-08 16:19:43 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
Field Performance Evaluation of Kwiq HIV 1/2 Test kit in Uganda.
REFNo: HS6240ES

1.To describe the performance (sensitivity and specificity) of the KWIQ-TEST rapid test compared to the reference testing (Genscreen ULTRA HIV1/2 Ag/Ab EIA followed by the Murex diasorin HIV1/2 Ag/Ab combination).
2.To describe the performance (sensitivity and specificity) of the KWIQ-TEST rapid test, when compared to the national testing algorithm.
3.Estimate the proportion of inconclusive test results by KWIQ-TEST Test

Uganda 2025-08-08 16:18:18 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
KEBIRUNGI ELIZABETH
ID: UNCST-2025-R017392
ETHNOLBOTANICAL, PHYTOCHEMICAL AND NUTRITIONAL PROFILES OF COMMONLY USED HERBAL GALACTOGOGUES AMONG BREAST FEEDING MOTHERS IN KISORO DISTRICT
REFNo: NS981ES

To profile the Ethnobotanical, Phytochemical, and Nutritional composition of commonly used plant based galactagogues by breastfeeding mothers. 1.3.1 Specific objectives i. To document the plant species used as galactagogues and associated local knowledge ii. To assess the phytochemical composition of selected plant based galactagogues used by breastfeeding mothers. iii. To determine the nutritional composition of selected plant based galactagogues used by breastfeeding mothers
Uganda 2025-08-08 14:01:54 2028-08-08 Natural Sciences Non-Clinical Trial Degree Award
Stephen Loro Loro Simon
ID: UNCST-2024-R016624
Enteral Feeding of premature neonates in Mbarara Regional Referral Hospital, Challenges and interventions
REFNo: HS6184ES

2. To develop a caretaker-led model of enteral feeding for premature neonates in MRRH using human-centred design approaches,To identify challenges that caretakers face while giving enteral feeding to premature neonates in MRRH. ,To establish the challenges that caretaker face while administering enteral feeds to preterm babies and develop a relevant intervention for care-taker led enteral feeding of premature neonates. ,
South Sudan 2025-08-08 13:59:50 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Odongo Samuel
ID: UNCST-2024-R016137
PATTERNS OF, FACTORS ASSOCIATED WITH, AND OUTCOMES OF SELF-MEDICATION AMONG CHILDREN AGED 1-59 MONTHS WITH ACUTE RESPIRATORY INFECTIONS AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS6188ES

3. To compare the seven-day in-hospital outcomes among children aged 1–59 months with ARI who have had self-medication by caregivers versus those who have not at MRRH.,2. To determine the factors associated with self-medication in children aged 1-59 months with ARI by caregivers at MRRH,1. To describe the patterns of self-medication among children aged 1-59 months with ARI by caregivers at MRRH.,To determine the patterns of, factors associated with, and in-hospital outcomes of self-medication in children aged 1-59 months with ARI by caregivers at Mbarara Regional Referral Hospital,
Uganda 2025-08-08 13:58:48 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
ROBERT BUGWATA
ID: UNCST-2024-R016476
Assessing the influence of Transformational Leadership Practices on Teacher Adaptability and Innovation in primary schools
REFNo: SS4052ES

1. To assess the prevalence and dimensions of transformational leadership exhibited by headteachers in Uganda’s primary schools. 2. To investigate the influence of headteachers’ transformational leadership on teachers’ adaptability in Uganda’s primary schools. 3. To examine the effect of headteachers’ transformational leadership on teachers’ innovation in Uganda’s primary schools.
Uganda 2025-08-08 13:57:34 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."