Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Willingness for COVID-19 vaccination, adherence to non-pharmaceutical interventions and associated factors among adults in Uganda: a computer assisted telephone interview survey
REFNo: HS1742ES

To determine the influence of vaccine introduction on adherence to COVID-19 NPIs among adults in Uganda.,To determine the influence of trust on willingness to vaccinate and adherence to NPIs among adults in Uganda.,To determine the adherence to COVID-19 NPIs and associated factors among adults in Uganda.,To determine the willingness for COVID-19 vaccination and associated factors among adults in Uganda.,To assess willingness for COVID-19 vaccination, adherence to NPIs and associated factors including trust among adults in Uganda to identify strategies to improve uptake of these interventions for COVID-19 prevention and control. ,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Preventing Intimate Partner Violence and Improving HIV Outcomes in Kampala, Uganda
REFNo: HS1843ES

AIM 1: Assess the reach, effectiveness, adoption, implementation and maintenance of national IPV guidance in HIV treatment and prevention settings in Uganda. We will conduct a cross-sectional evaluation using programmatic data from health facilities engaged in the parent study in order to determine the extent to which current national IPV guidance is implemented alongside existing HIV treatment and prevention services.

AIM 2: Identify provider-level barriers and facilitators to implementing national IPV guidance within HIV treatment and prevention settings in Uganda. We will conduct in-depth interviews with HIV providers from health facilities engaged with the parent study. Qualitative data will be thematically analyzed to explore opportunities to optimize and adapt strategies to more effectively intervene upon IPV in HIV care settings.

 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
 Healthcare workers’ Proficiency and Quality of Management for Snakebites in high burden Districts in Uganda
REFNo: HS2121ES

To explore the barriers faced in the management of snakebites in high burden districts in Uganda. ,To assess the quality of management for snakebites in high burden districts in Uganda.,• To assess the knowledge of health workers on snakebite management in two high burden districts in Uganda.,The overall objective is to assess health worker proficiency and quality of management of snakebites and associated barriers in high burden districts of Arua and Gulu so as to guide design of appropriate interventions to improve the quality of patient management and enhance favourable clinical outcomes. ,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Socio-demographic inequities in the risk of and response to Covid-19 in Uganda: a comparison of slum and estate communities
REFNo: HS2059ES

To determine the associations of practice of preventive measures with key social-demographic factors and other study variables between slum communities and suburb resident,To assess the variation in Psychosocial and economic impacts of Covid-19 between slum communities and suburb resident,To determine the difference Knowledge, perceptions and access to Covid-19 information between slum communities and suburb resident,To assess the difference in adoption of Covid-19 preventive measures and access to health services between slum communities and suburb resident,To conduct a comparative analysis of slum dwellers with economically-advantaged communities,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Integration of SARS-CoV-2 surveillance in the active and reactive screening activities of the Intensified Sleeping Sickness Elimination Program (ISSEP) in West Nile districts, Uganda
REFNo: HS2104ES

3. To demonstrate the feasibility of using a new tool to digitalize data capture and facilitate real-time data reporting of the HAT reactive and active community screening campaigns.,2. To conduct a serosurvey for antibodies against the SARS CoV-2 spike and nucleocapsid proteins to estimate the prevalence of community exposure.,1. To demonstrate the feasibility of integrating SARS-CoV-2 in the HAT reactive and active community screening campaigns to detect active symptomatic SARS-CoV-2 infection.,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Uganda Gender and Tuberculosis Key Populations Assessment
REFNo: HS1864ES

1. To establish the gender differences evident in TB care cascade (diagnosis through treatment) records in Uganda. 2. To determine the gender barriers and facilitators to TB prevention, diagnosis, treatment and treatment completion in Uganda. 3. To generate information to guide the listing of TB KVPs relevant to Uganda context, and for designing interventions for addressing the gaps among prioritized KVPs. 4. To determine to what extent the National TB response (NSP and policies/guidelines) addresses gender and KVP issues in Uganda.
 Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Exposure-Response Evaluation of IV Artesunate in Children with Severe Malaria
REFNo: HS2027ES

Primary:
• To determine the relationship between dihydroartemisinin (DHA) exposures following intravenous dosing and markers of physiologic dysfunction associated with severe malaria
Secondary:
• To determine the relationship between DHA exposures and time to hospital discharge
• To determine the relationship between DHA exposures and parasite clearance associated with treatment of severe malaria.
Exploratory:
• To determine the relationship between DHA exposures and neurodevelopmental outcomes associated with treatment of severe malaria outcomes and explore predictors that may affect this relationship
• To evaluate the role of parasite clearance as a mediator of the relationship between DHA exposures and markers of physiologic dysfunction associated with severe malaria
• To develop a score comprised of markers of physiologic dysfunction and describe its relationship to clinical outcomes
• To assess P. falciparum infections for artemisinin resistance

Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
Danielle Falk
ID:
Educators in Emergencies: The Lived Experiences and Professional Identities of Refugee and National Primary School Teachers in Uganda and South Sudan
REFNo: SS1213ES

To determine in what ways teachers conceptualize their professional identities,To understand how protracted conflict, forced displacement, and recurrent migration influences teachers’ lived experiences in their classrooms, schools, and communities in refugee-producing and receiving countries,To explore the lived experiences and professional identities of refugee and National Primary School Teachers in Uganda and South Sudan,
 USA 2022-03-14 2025-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Wambuzi
ID:
Community Engagement Strengthening for future HIV Vaccice trial participation in fishing communities around Entebbe,Uganda( CEVAC)
REFNo: SS1201ES

1. To assess knowledge on HIV vaccine trials among people living in FCs around Entebbe, Uganda.
2. To assess willingness to participate in future HIV vaccine trials among people living in FCs around Entebbe, Uganda.
3. To understand HIV vaccine trials experiences and motivators to participation among former participants.
4. To explore communities’ experiences, perceptions and preferences for community engagement among FCs around Entebbe, Uganda.

 Uganda 2022-03-11 2025-03-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ambrose Oruni
ID:
Impact of escalating insecticide resistance on malaria control tools and parasite transmission in An. funestus from Uganda
REFNo: HS2063ES


i. Temporal monitoring of super-resistance every 6 months for 3 years. The frequency of the known resistance markers, changes in transcription profiles of resistance genes and variations in the genome will be monitored.

ii. Assess the impact of super-resistance on the effectiveness of the current and novel bednets against An. funestus.

iii. Assess the impact of super-resistance on malaria entomological transmission indices.

 Uganda 2022-03-11 2025-03-11 Medical and Health Sciences Non-Clinical Trial Degree Award
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