Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Peter Olds
ID: UNCST-2023-R006240
Developing Better Control Together, a multi-faceted patient-support group for patients with hypertension in Uganda
REFNo: HS5309ES

We propose to develop a multi-faceted patient-support group for patients living with HTN in rural Uganda using an iterative approach that is tailored to the local context. We will adapt several evidence-based interventions for patient-support groups from the HIV experience to develop a comprehensive intervention for patients with HTN by including aspects of disease education, social support, financial activities, and bulk purchasing of HTN medications.
USA 2025-01-22 16:51:40 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Rwankangi
ID: UNCST-2024-R016056
Solar-Powered Irrigation Schemes for Smallholder Farmers in Uganda: Assessing Impact and Sustainability
REFNo: SIR452ES

1. To examine the impact of adopting solar-powered irrigation systems on crop
yields in horticulture among smallholder farmers in eastern Uganda.

2. To examine how farmers’ knowledge and skills in operating and maintaining
solar irrigation systems influence the adoption of solar-powered irrigation
technology among smallholder farmers.

3. To analyze the effect of stakeholder engagement on the adoption of solar-
powered irrigation technologies among smallholder farmers.

4.To assess how the Ugandan Government’s policy frameworks influence, the
adoption of solar-powered irrigation technology among smallholder farmers.

Uganda 2025-01-22 16:49:32 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
Functional Role, Temporal Dynamics, and Protective Impact of IgA on Clinical Outcomes in Uncomplicated Plasmodium falciparum Malaria
REFNo: HS5353ES

General Objective
To investigate the functional role, temporal dynamics, and protective impact of IgA on clinical outcomes in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda.
Specific Objectives
1. To quantify the functional activity of serum IgA antibodies in adult patients with uncomplicated Plasmodium falciparum malaria in the greater Kampala region, Uganda, by measuring the percentage reduction in hepatocyte infection, the inhibition of merozoite invasion of erythrocytes, and the level of neutrophil activation through oxidative burst and cytokine release.
2. To characterize the temporal dynamics and persistence of IgA responses in adult patients with uncomplicated malaria in the greater Kampala region over a 42-day follow-up period, by measuring peak IgA levels (C_max), time to peak level (T_max), rate of decline (IgA half-life), and area under the curve (AUC).
3. To evaluate the association between serum IgA levels and clinical outcomes in adult patients with uncomplicated malaria in the greater Kampala region, by assessing symptom resolution time and parasite clearance time.
4. To determine the correlation between IgA levels and complement activation, as well as their association with pro-inflammatory or regulatory cytokines during and after Plasmodium falciparum infection in adult patients with uncomplicated malaria in the greater Kampala region, Uganda.

Uganda 2025-01-22 16:47:42 2028-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dina Nabasumba
ID: UNCST-2023-R006504
Crop production dynamics and vulnerability to food insecurity in the face of climate variability: A case of smallholder farmers in south-western Uganda
REFNo: A524ES

4. To classify the extent and factors controlling the influence of climate variability on vulnerability to food insecurity among smallholder farmers in south-western Uganda,3. To determine the influence of spatial-temporal rainfall variability on adoption patterns of land-based climate smart agricultural practices in seasonal cropping systems of smallholder farmers in south-western Uganda ,2. To establish the relationship between smallholder farmers’ knowledge, attitudes and adoption of climate smart agricultural practices in south-western Uganda,1. To assess smallholder farmers’ perceptions of climate variability and the extent to which it has altered crop selection and cultivation patterns in south-western Uganda,To establish the influence of climate variability on the crop production systems and vulnerability to food insecurity among smallholder farmers in south-western Uganda,
Uganda 2025-01-22 16:46:28 2028-01-22 Agricultural Sciences Non-Clinical Trial Degree Award
Chikadibia Uche Kalu Awa
ID: UNCST-2024-R003818
OPTIMIZATION OF MIX DESIGN FOR STRUCTURAL LIGHTWEIGHT CONCRETE (SLWC) WITH ARTIFICIAL AGGREGATES USING RESPONSE SURFACE METHODOLOGY
REFNo: SIR344ES

1. To produce and characterize artificial aggregates from polyethylene terephthalate plastic waste.
2. To design experimental mixture proportions for S.L.W.C. using mathematically independent variable (factorial) approach.
3. To evaluate the performance of S.L.W.C. regarding density, splitting tensile strength, compressive strength, workability, and durability.
4. To apply response surface methodology for the analysis of the obtained results to derive model equations for each performance criteria.
5. To optimize (S.L.W.C.) using desirability function.
6. To carry out microstructural analysis of the specimens.

Nigeria 2025-01-22 16:45:23 2028-01-22 Engineering and Technology Non-Clinical Trial Degree Award
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