Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Roy Mayega William
ID: UNCST-2022-R010983
Uganda Non-State Schools Assessment
REFNo: HS2516ES

4. To assess the capacity of non-state pre-primary and primary schools to sustainably finance quality education.,3. To explore the oversight and regulation functions among non-state pre-primary and primary schools.,2. To understand the barriers faced by learners from traditionally marginalized groups in accessing non-state pre-primary and primary schools in urban and peri-urban centers. ,1. To determine the quality of education in non-state pre-primary and primary schools in urban and peri-urban areas of Uganda, especially in light of the recent COVID-19 pandemic.,To determine the factors that influence the quality and level of access to non-state primary and pre-primary schools in urban and peri-urban areas of Uganda. ,
Uganda 2023-02-21 12:53:41 2026-02-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
THE SECOND UGANDA NATIONAL ANTI-TUBERCULOSIS DRUGS RESISTANCE SURVEY(DRS2)
REFNo: HS2652ES

To identify the demographic and clinical factors associated with drug resistance in Uganda including HIV, tobacco smoking, diabetes and alcoholism.,To determine circulating strains of MTB in the general population among PBCs in Uganda.,To determine the prevalence of resistance mutations to all first- and second-line drugs in use in Uganda.,To determine the prevalence and patterns of drug resistance to fluoroquinolones, Bedaquiline, Delamanid, clofazimine, amikacin, and Linezolid among patients with confirmed RR-TB in Uganda.,To determine the prevalence of resistance to HRZE among new and previously treated PBC patients in Uganda.,To measure the prevalence of RR-TB among bacteriologically confirmed pulmonary TB (PBC) patients in Uganda. ,
Uganda 2023-02-20 13:22:01 2026-02-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wietse Tol
ID: UNCST-2021-R013085
AlCohol use in HumanitariAN settings: a programme of work to address alcohol use disorders and associated adversities among conflict-affected populations in UGanda and UkrainE (CHANGE)
REFNo: SS1596ES

• To identify strategies and techniques from evidence-based alcohol use therapies which can be integrated into PM+, and to develop a new intervention called PM+A (Problem Management Plus Alcohol)
• To adapt PM+A to local circumstances, and to examine the feasibility, acceptability, perceived effectiveness, and preliminary impact of PM+A
• To evaluate effectiveness and cost-effectiveness of PM+A through two single-blind randomised controlled trials in Uganda and Ukraine
• To explore the process of implementation, and to identify, characterise and explain mechanisms that promote or inhibit the delivery and take-up of PM+A in both settings
• To examine the potential for scaling-up PM+A in Uganda and Ukraine

Netherlands 2023-02-17 12:18:30 2026-02-17 Social Science and Humanities Clinical Trial Non-degree Award
Silver Onyango
ID: UNCST-2022-R009337
Ambient air pollution and lung health in rural sub-Saharan Africa: The impact of biomass on vulnerable populations
REFNo: HS2657ES

Characterize the relationship between chronic ambient air pollution exposure and lung function trajectory and structural abnormalities. Validate satellite-based calculations of PM2.5 and test inexpensive optical particle counters for future monitoring,Characterize ambient air pollution levels and sources in rural southwestern Uganda ,Characterize the effect of ambient air pollution and sources on lung function among vulnerable people in rural south western Uganda. ,
Uganda 2023-02-15 17:05:50 2026-02-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
BACKTRACK: A technology enabled care pathway delivered by clinical officers and nurses to manage low back pain
REFNo: HS2636ES

BACKTRACK will enable the clinical officer or nurse to identify the cases that should be referred onwards for specialist assessment and intervention such as physiotherapy,BACKTRACK will enable the clinical officer or nurse in dispatching evidence based self-management advice,BACKTRACK will enable the clinical officer or nurse to safely identify LBP cases that are amenable to self-management,to develop and evaluate a digital clinical decision support system (DCDSS) called BACKTRACK. ,to improve access to rehabilitation for people with low back pain to reduce its disability burden, and to improve functional and participatory outcomes (such as return to work or school).,
Uganda 2023-02-15 16:53:46 2026-02-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles Bawate
ID: UNCST-2022-R009806
Determinants and impact of health education intervention on patients' adherence to Arteminsinin-based combination therapy treatment in Kamuli District, Uganda
REFNo: HS2576ES

General Objective
To assess the determinants and the impact of health education intervention on patients' adherence to ACT treatment in kamuli District, Uganda.

Specific Objectives
1. To determine the level of patients' adherence to ACT in the case management of malaria in Kamuli District, Uganda.
2. To determine the factors influencing patients' adherence to malaria ACT treatment in Kamuli District, Uganda.
3. To establish the impact of a health education intervention on the patients' adherence to malaria ACT treatment in kamuli District, Uganda.
Uganda 2023-02-15 16:35:05 2026-02-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackline  Kiwelu Estomihi Mayende
ID:
Evidence-based information practice framework for maize postharvest handling by rural smallholder farmers in Uganda.
REFNo: SS1435ES

1. Evaluate the current status
of evidence-based
information practices by
maize smallholder farmers in
Uganda concerning maize
postharvest handling.
2. Describe the evidence
information practice needs
for rural smallholder farmers
as far as maize postharvest
handling is concerned.
3. Explain the access and use
of the available maize postharvest
handling evidence-based
information practice.
4. Describe difficulties that
smallholder farmers and
extension service librarians
are experiencing with the
available maize postharvest
handling evidence-based
information practice in terms
of access and use.
5.
5. Propose evidence-based
information practice
framework for maize
postharvest handling by rural
smallholder farmers in
Uganda.
Tanzania 2023-02-15 16:33:01 2026-02-15 Social Science and Humanities Non-Clinical Trial Degree Award
Casey Crow Lynn
ID:
Exploring Sexual and Reproductive Health and Rights Amongst Refugees with Disabilities in Uganda
REFNo: SS1611ES

4. To identify barriers and facilitators to accessing SRHR-related services with the aim of improving uptake and informing future service provision.,3. To explore how disability, migration, and access to sexual and reproductive health influence lived experience from micro (individual, family, intimate relationships), to meso (school, community, NGOs, healthcare), to macro (societal, policy) levels. ,2. To describe how refugees with disabilities navigate and resist violence, stigma, and marginalisation of their sexual and reproductive health and rights.,1. To explore the ways disability and migration interact in the process of seeking sexual and reproductive health services.,To explore the SRHR-related lives, needs, contexts, and access to services amongst refugees with disabilities in Uganda.,
USA 2023-02-14 17:15:17 2026-02-14 Social Science and Humanities Non-Clinical Trial Degree Award
JOHNBAPTIST BWANIKA
ID:
A Research study to understand the impact and cost-effectiveness of a digital health platform for iCCM in Uganda
REFNo: HS2645ES

Specific objectives
1.Determine the impact of the eCHIS intervention on OPD attendance (due to malaria, pneumonia and diarrhoea) among children under five,
2.Determine the impact of the eCHIS intervention on hospitalisation (due to malaria, pneumonia and diarrhoea) among children under five,
3.Determine the impact of the eCHIS intervention on malaria related mortality in the community and health facilities among children under five,
4.Determine if translating the eCHIS into the local language improves VHTs’ service delivery (satisfaction, confidence, accuracy, interpretation, and quality),
5.Determine the cost-effectiveness of implementing the eCHIS intervention.

Secondary objectives
1.To assess the data quality of VHT monthly digital reports,
2.To assess use of digital dashboards for decision-making at HF and district level,
3.To assess the proportion of the devices still functioning each month throughout the study and document reasons why they malfunctioned,
4.To assess maintenance requirements

Uganda 2023-02-14 16:58:01 2026-02-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ham Wasswa Matovu
ID:
ASSESSMENT OF POST INTENSIVE CARE UNIT OUTCOMES AND FACTORS ASSOCIATED WITH 90-DAY MORTALITY AMONG ADULT PATIENTS
REFNo: HS2143ES

1. To determine the factors associated with 90-day mortality of patients discharged from three tertiary hospital ICUs in Kampala.,2. To determine the physical functional status of ICU survivors at 90 days following discharge from three tertiary hospital ICUs in Kampala.,1. To determine the 90-day mortality rate of patients discharged from three tertiary hospital ICUs in Kampala.,To determine the 90-day mortality rate, functional status and risk factors for mortality among patients discharged from 3 tertiary hospital ICUs in Kampala.,
Uganda 2023-02-14 14:38:03 2026-02-14 Medical and Health Sciences Non-Clinical Trial Degree Award
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