Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
 A multiple arm, multiple stage (MAMS), phase 2B/C, open label, randomized, controlled platform trial to evaluate experimental arms including an increased dose of rifampicin, an optimized dose of pyrazinamide, moxifloxacin and sutezolid, in adult subjects with newly diagnosed, smear-positive pulmonary tuberculosis
REFNo: HS2644ES

Primary Efficacy Objective:
Rifampicin- containing experimental arms (arms 1,2)
To evaluate whether one or more of two experimental regimens based on
optimized dose rifampicin, optimized dose of pyrazinamide, and moxifloxacin
given for 12, respectively 17 weeks, are superior to standard treatment given for
26 weeks, as assessed by time to sputum culture conversion to negative in liquid
media.
Sutezolid-containing experimental arm (arm 4)
 To evaluate whether the efficacy of an experimental regimen composed of
sutezolid, delamanid, bedaquiline, and moxifloxacin given for 17 weeks is
superior to standard treatment given for 26 weeks, as assessed by time to
sputum culture conversion to negative in liquid media.
Secondary Objectives This study’s secondary objectives are:
Efficacy
 To assess treatment efficacy based on proportion of patients with relapse
free outcome at 12 months after randomization.
 To assess treatment efficacy based on the rate of decline of bacterial load
measured by the Molecular Bacterial Load Assay
 To rank the relative efficacy of the experimental four-drug combinations
for the treatment of pulmonary tuberculosis within the first twelve weeks
of treatment, and select the most efficient experimental treatment
regimen or regimens for further development.
Safety and Tolerability
To assess the frequency, severity, and type of adverse events (AEs), and AErelated
treatment discontinuations.
Pharmacokinetics
To describe the pharmacokinetics of the drugs and doses used, and to assess
possible relationships between pharmacokinetic parameters of the various drugs and between pharmacokinetic parameters and participant characteristics.
Pharmacodynamics To describe relationships between pharmacokinetic parameters on the one hand and efficacy and safety endpoints on the other hand.
 Uganda 2023-04-11 15:27:11 2026-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Andrew Muhumuza
ID: UNCST-2022-R009010
 Incidence and predictors of castration resistance among patients with prostate cancer on androgen deprivation therapy at two referral hospitals in Uganda
REFNo: HS2759ES

To identify the predictors of castration resistance among prostate cancer patients on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital. ,To determine the incidence of castration resistance among patients with prostate cancer on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital.,To determine the incidence and predictors of castration resistance among prostate cancer patients on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital.,
 Uganda 2023-04-11 14:20:29 2026-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
SAM ALI
ID: UNCST-2020-R014824
 Stillbirth in High Burden Settings: Ample Room for Improvement using Biomarkers and Ultrasound Technologies (iTECH)
REFNo: HS2762ES

1. To evaluate the relation between placental histopathological lesions and biomarkers, placenta ultrasound and hemodynamic changes after stillbirth and near miss stillbirth in order to understand the underlying mechanisms and specify the prediction model. 2. To engage with important stakeholders on the value of these diagnostic technologies in the community, co-creating the project design, implementation and eventual uptake into practice guidelines. 3. To establish the predictive performance of maternal characteristics and markers emerging from this project for stillbirth and other related endpoints in non-anomalous fetuses and assess the feasibility of integrating relevant markers into clinical decision support tools. 4. To prospectively evaluate patterns of (bio)markers, maternal cardiovascular function and contemporary ultrasound markers in pregnancy, to understand their role in the chain of events and pathophysiology of stillbirth in a resource poor setting. 5. To develop and validate a prediction model for use at the point of care in low-and middle-incomes countries (LMICs) to quantify a woman’s individual risk of antepartum stillbirth based on a set of easily measurable, accessible, highly predictive and cost-effective markers, and make it freely available for healthcare providers in low-resource settings.
 Uganda 2023-04-06 8:06:27 2026-04-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juliana Namutundu
ID:
IMPROVING CERVICAL CANCER SCREENING LITERACY AMONG HIV-INFECTED WOMEN IN CARE AT RURAL PUBLIC HEALTH FACILITIES IN EAST CENTRAL UGANDA
REFNo: HS2753ES

3) To assess the feasibility, acceptability and preliminary effectiveness of a cervical cancer screening literacy improvement implementation strategy for Women living with HIV in care at rural public health facilities in East Central Uganda.,2) To design a cervical cancer screening literacy improvement implementation strategy for Women living with HIV in care at rural public health facilities in East Central Uganda.,1) To conduct a multi-level assessment of barriers and facilitators of cervical cancer screening literacy among HIV-infected women in care at rural public health facilities in East Central Uganda.,
 Uganda 2023-04-05 17:05:10 2026-04-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Nafuna Sarah
ID:
EXAMINING MOTIVATIONAL STRATEGIES INFLUENCING PERFORMANCE OF TUTORS IN CORE PRIMARY TEACHERS’ COLLEGES IN EASTERN UGANDA
REFNo: SS1647ES

3. To analyse the challenges that may influence the effective motivation of tutors in Core PTCs in Eastern Uganda.,2. To examine the views of tutors on how motivational strategies affect their performance in Core PTCs in Eastern Uganda.,1. To investigate motivational strategies employed in Core PTCS in Eastern Uganda. ,
 Uganda 2023-04-04 9:36:11 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Milcah Abasabyona
ID:
Intimacies of Identification and Lived Citizenship among the Ghetto Youths in Kampala, Uganda
REFNo: SS1654ES

Main Objective:
To investigate how citizen certification and identification influences levels of belonging to a place and space, impacts on citizen-state relationship and individual personhood.
Specific Objectives:
1. To capture the individual practical experiences of legal certification and identification processes among the Ghetto youths.
2. To examine the regulatory effects of identification documents on citizenship rights, a sense of belonging, and personhood among the Ghetto youths in Kampala.
3. To explore the different key Identification documents and their role in the day to day lives of the Ghetto Youths.
4. To trace the ways in which the undocumented Ghetto youths create alternative routes to lived citizenship and self-certification.
 Uganda 2023-04-04 9:32:41 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
ANYASE AMAZA RONALD
ID: UNCST-2022-R009325
 Development of a Natural Anti-Aflatoxin Product
REFNo: HS2692ES

To develop a prototype natural based anti-aflatoxin product made from Ugandan plants.,To establish a database of plants in Uganda with anti-aflatoxin potential,To determine the indigenous approaches of aflatoxin control in Uganda.,To develop a natural based anti-aflatoxin product ,
 Uganda 2023-04-03 21:04:19 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Professional Identity of Ugandan Nurses and Midwives: Exploring the understanding, Perceptions and Experiences among student Nurses and Midwives, Recent Graduates and Nurse Educators
REFNo: HS2712ES

Explore nurse and midwife top management in the ministry of health and nurses and midwives council perception and experiences fostering professional identity in nursing in the country.,3. Explore nurse and Midwife educators’ perceptions and experiences fostering professional identity in nursing and midwife at Mbarara University of Science and Technology and Makerere university,2. Explore challenges and barriers to professional identity formation at Mbarara University of Science and Technology and Makerere University,1. Describe the understanding of the professional identity of final year undergraduate nurses and midwives and recent graduates at Mbarara University of Science and Technology and Makerere University.,
 Uganda 2023-04-03 21:00:42 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
zaina Nakabuye
ID:
Technology orientation and the export performance of SME exporting firms in Uganda.
REFNo: SS1472ES

2. To establish the relationship between knowledge absorptive capacity and export performance.
3. To examine the relationship between supply chain agility and export performance.
4. To investigate the moderation of knowledge absorptive capacity between technology orientation and export performance.

5. To investigate the moderation of supply chain agility between technology orientation and export performance.

 Uganda 2023-04-03 20:58:43 2026-04-03 Social Science and Humanities Non-Clinical Trial Degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
 Development and assessment of an HIV disclosure intervention for men in Uganda - Aim 1
REFNo: HS2682ES

Aim 1. Identify the unique HIV disclosure needs and preferences among MWH to support HIV disclosure. ,
 USA 2023-04-03 20:55:31 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 Prevalence of and factors associated with mental disorders and coping mechanisms among students at Busitema University.
REFNo: HS2700ES

To explore factors influencing mental disorders among students at Busitema UniversityTo explore the coping mechanisms used by students at Busitema University
 Uganda 2023-04-03 20:53:26 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Qualitative research to prepare for novel HIV prevention products
REFNo: HS1749ES

Define a preliminary strategy for the integration of novel PrEP products (e.g., injectable Cabotegravir, Dapivirine intravaginal ring, TFV/LNG intravaginal ring) into existing oral PrEP programs by conducting qualitative interviews with experts in novel PrEP products, oral PrEP programs, and end users.
To achieve this aim, we will conduct approximately 60 key informant interviews (KII) with: 1) clinical trialists leading studies of novel PrEP products, 2) oral PrEP program leaders in sub-Saharan Africa and 3) young women in Uganda who have decided not to use oral PrEP during recent PrEP studies.

Uganda 2023-04-03 20:51:28 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 Prevalence of intestinal colonization by ESBL-producing Enterobacterales in neonates at Jinja Regional Referral Hospital
REFNo: HS2737ES

• To highlight the area of antibiotic resistance in neonates in this setting ,• To conduct a point-prevalence surveillance of ESBL-producing Enterobacterales in the neonatal unit at two specific time-points with two weeks apart.,The overall aim of this project is to create base-line data for future infection prevention control strategies in the area of newborn care at Jinja Referral Hospital.,
 Uganda 2023-04-03 20:49:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Maris Nanyonga
ID:
Optimizing antimicrobial use in the management of Upper Respiratory Tract Infections through antimicrobial stewardship in Community Pharmacy practice in Uganda; A patient centered approach
REFNo: HS2617ES

Primary Objectives 1. To assess the knowledge, attitude, and practice (KAP) towards self-medication among patients who visit community pharmacies for the management of Upper respiratory tract infections. 2. To explore the barriers and facilitators of self-medication in the community. 3. To explore prescriber views and understanding on the use of delayed prescribing in primary care. Secondary Objectives 4.To evaluate the effectiveness of training and delayed prescribing intervention on antibiotic consumption among patients with URTI who visit community pharmacies. 5. To describe dispensing and prescribing patterns of pharmacy staff when managing patients with upper respiratory tract infections at the community pharmacy
Uganda 2023-04-03 20:46:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Kakayi Catherine
ID: UNCST-2022-R008787
 Insulin-like Growth Factor/Growth Hormone Levels and Stunting in HIV Exposed Uninfected Children from the 1077BF/P1084s study (CHASE: Changes in IGF/Hormone Axis and Stunting in HIV-Exposed uninfected children.
REFNo: HS2686ES

1. To investigate IGF-1, IGFBP-1, and IGFBP-3 as predictors of growth faltering/stunting in the first 2 years of life in HEU children

2. To describe the concentrations of hormonal growth factors in infants in relation to infant growth percentile at birth, 26 weeks, and 74 weeks of age.

Uganda 2023-04-03 20:41:44 2026-04-03 Medical and Health Sciences Clinical Trial Non-degree Award
Gerald Bareebe
ID:
Violence and Regime Trajectories in Post-Conflict Uganda and Rwanda
REFNo: SS1413ES

This study is driven by two important objectives: the first is the need to consider the influence of a “residue” social structure. What the cases of Uganda and Rwanda tell us is that, without understanding the underlying socio-political agency of the political regime and the armed elites that run it (and without knowing who their allies are or what the sources of constraints in that process are), it is difficult to resolve the socio-political problems that trouble most postwar states on the continent. The second is the need to show how post-war reconstruction in Africa is a function of elite interactions. The failure to understand this phenomenon has left post-conflict societies more vulnerable to conflict relapse. By investigating the interface of power elites in post-war state reconstruction, this research situates itself within a more empirical and contemporary African perspective and elevates the importance of social actors, specifically those whose actions reflect the intractability of power struggle. Specifically, the research seeks to achieve the following objectives:

 To understand the process of post-conflict state reconstruction in Uganda and Rwanda
 To understand factors that may hinder or enable the rebuilding of state institutions after a civil war.
 To compare the experience of Uganda and Rwanda with regards to how they both approached state reconstruction after a devastating civil war.
 To determine the nature and impact of policies taken by state-builders in both Uganda after the 1986 civil war and Rwanda after the 1991 genocide.

Uganda 2023-04-03 16:49:25 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy Allen Peter
ID: UNCST-2019-R001369
 Public Authority and International Development Uganda Programme Phase 2
REFNo: SS1678ES

Inductive theory-building through comparative applications,New curriculum development for scholars and development professionals,Reciprocal capacity-building in the academy and knowledge production,Reflexive policy-making and governance impact,Generate impact, knowledge exchange and capacity building through a public authority lens,
 UK 2023-04-03 16:41:36 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesse Rudy Lynn
ID: UNCST-2023-R008208
 Prevalence of property Grabbing among widows in Uganda
REFNo: SS1677ES

To establish the total number of people protected in the different project areas districts as a result of Redeem’s program interventions., 1)To understand the indirect consequences of attempted and successful land/property grabbing for widows and orphans in the aftermath of the events, 2)To ascertain the criminal, violent or other means used by perpetrators to victimize widows and orphans through grabbing property or land in Uganda., 3)To determine the prevalence of property grabbing from widows in targeted areas of Uganda, 4)To measure the annual burden of property grabbing in the selected case work areas ,
 USA 2023-04-03 15:40:08 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
GRACE MARY KENYONGA
ID:
Attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda
REFNo: SS1473ES

General aim
Examine the attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda.
Specific Objectives
1. Explore the attitudes women have towards PrEP
2. Identify the factors that influence the present attitudes towards PrEP
4. Identify other community variables that may encourage or constrain the uptake of PrEP.
6. Identify and recommend necessary interventions and measures to counteract any prevailing negative attitudes towards PrEP that may be prevailing in the community.

 Uganda 2023-03-28 1:00:59 2026-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
 Risk factors for severe schistosomal morbidity: an adult case-control study by the Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)
REFNo: HS2570ES

We hypothesise that factors at each step of the parasite life cycle interact to determine morbidity in schistosomiasis. The objective of this work is to investigate risk factors associated with advanced schistosomiasis morbidity among adults, using a case-control study.
UK 2023-03-24 2:35:04 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Birungi Edwin Mutahunga Rwamatware
ID: UNCST-2021-R004880
 Prevalence and predictors of antimicrobial resistance in clinical- and community-acquired upper respiratory bacterial samples in children under 5 in south-western Uganda
REFNo: HS2625ES

Upper respiratory infections are the second leading cause of death in children under 5 in Uganda, and account for 40% of all under-5 outpatient attendance at clinics and hospitals nationwide in Uganda. As bacterial cultures of lung aspirates are often not practical, the WHO recommends using a rapid breathing and chest wall in-drawing to diagnose pneumonia in children under 5, and recommends treatment with oral amoxicillin or co-trimoxazole, or intramuscular penicillin. The only study of anti-microbial resistance (AMR) in nasopharyngeal bacteria in Uganda comes from healthy children in the Iganga/Mayuge region (Eastern Uganda), where the authors found that one-third of children were given a self-prescribed antibiotic within the past two weeks for fever, running nose, or cough, that 60% carried Streptococcus pneumoniae, and that a high proportion (80% to 99%) of cultures were resistant to co-trimoxazole, penicillin, and oxacillin. At Bwindi Community Hospital, suspected acute respiratory infections accounted for 75% of all under-5 outpatient diagnoses in 2015/2016, and are the most common reason for under-5 admissions to the Pediatrics Ward (e.g., 34% of 830 admissions in 2015/2016). In addition, the majority of antibiotics prescribed for both children and adults were for suspected acute respiratory illness (5,273 of 17,910 prescriptions). Our proposed study seeks to build on previous work concerning Antimicrobial Resistance in the developing world with a specific focus, on clinical- and community-acquired upper respiratory bacterial infections in children under 5 in southwestern Uganda, and it will be the first to analyse spatio-temporal patterns of resistance and explicitly link those patterns to cultural and social characteristics and behaviours on the ground as well as healthcare infrastructure. We propose a multi-layered study to; 1) Analyze the prevalence and spatial associations of antibiotic resistance in nasopharyngeal bacterial isolates from children under 5 in the Bwindi Community Hospital (BCH) catchment area for a year in Kanungu District, Southwestern Uganda. 2) Assess the use of antibacterial drugs at home to treat acute respiratory illness in these children from children under 5 in the Bwindi Community Hospital (BCH) catchment area in Kanungu District 3) Assess practices of antibiotic distribution at drug shops in the BCH catchment region.
Uganda 2023-03-24 2:31:31 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 Investigating determinants of varying schistosomal morbidity among preschool-age children in the Lake Albert and Lake Victoria regions: a cohort study by the Uganda Schistosomiasis Multidisciplinary Research Center
REFNo: HS2568ES

Our main objective is to understand the biological determinants of severe Schistosoma mansoni-associated morbidity and to identify better strategies for its prevention and control. Our specific objectives are to: 1. Compare, in pre-school age children, early-life Sm infection and Sm-specific immune responses between Lake Albert and Lake Victoria regions and identify co-exposures that modulate Schistosoma mansoni-specific immune responses and morbidity risk 2. Determine if there is a parasite genetic basis for differential Schistosoma mansoni morbidity 3. Determine how the population biological determinants of fresh-water snail Biomphalaria spp. act as local epidemiological drivers of Schistosoma mansoni
 UK 2023-03-24 2:29:21 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olive Kobusingye Chifefe
ID:
Building the evidence-base for the integration of rehabilitative services into health systems – a case study of clubfoot treatment in Uganda
REFNo: HS2614ES

The study has two aims, each with subsequent research questions: Aim 1: To explore how policy makers, health providers, and caregivers define, understand and experience service integration and the potential implications for clubfoot treatment. (Qualitative) • How do health care providers define and experience service integration, and what are the impacts of integration on their day-to-day clinical operations, workflow, and roles? • How do district- and national-level bureaucrats and donors understand integration, and how does that shape integration of clubfoot treatment? • How do caregivers understand and experience integration, and how does it impact their child’s treatment? • How is the NCPU financed and what relationship does financial contribution have with integration? Aim 2: To improve understanding of how the CAST mobile health application (CAST) impacts health providers’ behavior, and what potential impacts the CAST could have on service quality. (Mixed) • What is the reach and adoption rate of CAST and its components among eligible Ugandan providers? • How might CAST modify provider behavior at the facility level, both for clubfoot treatment and other services? • How might the CAST facilitate quality of care and patient treatment? o How do supportive services from MiracleFeet/CoRSU contribute to this? (e.g. training, supportive supervision, help desk) o How does data from and usage of the Cast Community contribute to this? • What is the potential future of the CAST if external support is withdrawn from clubfoot treatment and all services are fully managed by the public sector?
Uganda 2023-03-24 2:25:26 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE)
REFNo: HS2659ES

Primary Objective:
To compare the proportion of children aged 5-17 years with latent RHD receiving oral penicillin prophylaxis who progress to worse valvular disease at 2-years compared to children who receive IM penicillin prophylaxis.

 Uganda 2023-03-24 2:23:26 2026-03-24 Medical and Health Sciences Clinical Trial Non-degree Award
Samuel Ojelel
ID: UNCST-2019-R000996
 Tropical Important Plant Areas of Uganda
REFNo: NS479ES

(i) To assess conservation status of priority plant species to guide Identification of Important Plant Areas

(ii) To promote sustainable use and protection of Important Plant Areas by developing partnership with key stakeholders

 Uganda 2023-03-24 2:17:32 2026-03-24 Natural Sciences Non-Clinical Trial Non-degree Award
Denis Muhangi
ID: UNCST-2020-R014258
 A STUDY ON CONDOM DEMAND, UTILIZATION, DISTRIBUTION AND DISPOSAL SURVEY 2022
REFNo: SS1605ES

1. To establish the condom demand for both the male and female condom users in the community programming in 61 districts of Uganda 2. To generate information on distribution and utilization of condoms among key, priority and general population in 61 districts of Uganda 3. To generate data to be used to fill gaps in comprehensive condom programming in relation to condom demand, distribution, management and disposal as well as modalities for strengthening condom logistics in Uganda 4. To explore new modalities for strengthening condom logistics among the non-traditional channels of condom distribution in the community. 5. To determine the extent of adherence to the condom waste management and disposal mechanisms developed by MoH, 6. To establish status and opportunities of using the Total Market Approach
 Uganda 2023-03-24 2:13:39 2026-03-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Caroline  Nerima
ID:
FUNCTIONAL LIMITATIONS AMONG CHILD REFUGEES WITH DEVELOPMENTAL DISABILITIES AND BARRIERS TO EARLY CHILDHOOD INTERVENTION IN A UGANDAN REFUGEE SETTLEMENT.
REFNo: HS2666ES

1. To describe the functional limitations among children aged 1 month to 6 years with developmental disabilities.
2. To describe the early intervention services available for children with developmental disabilities living in refugee camps.
3. To describe the barriers to access to early intervention services for children with developmental disabilities.


Uganda 2023-03-24 2:10:43 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
 Tuberculosis, Alcohol, and Lung Comorbidities (TALC) Study
REFNo: HS2705ES

Qualitatively evaluate factors for tailoring pharmaco-behavioral alcohol and smoking interventions in PLWH being treated for TB. ,Explore how smoking alters the association of past-month heavy drinking and post-TB lung disease progression over time,• Aim 1b. Assess the association of past-month heavy drinking and post-TB lung disease progression over time. This aim uses recent alcohol use (30-day Timeline Followback, PEth) since direct mechanisms (e.g., alcohol toxicity) may drive the physiologic, anatomic, and immunologic outcomes of interest. We define past-month heavy drinking as ≥7 drinks/week (women), ≥14 drinks/week (men) or PEth>200 ng/mL.,• Aim 1a. Determine if past-year hazardous drinking is associated with post-TB lung disease. ,Aim 1. Determine the relationship between hazardous drinking and post-TB lung disease in PLWH.,
 Uganda 2023-03-24 2:08:05 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Muhangi
ID: UNCST-2020-R014258
 Sustainable Off-Grid Solutions for Pharmacies and Hospitals in Africa (SophiA). Sub-component 1: Needs Assessment of Hospitals/Health Centre IVs for the Sustainable Off-Grid Solutions Sub-component 2: Socio-Economic Acceptance and Participation Assessment for Stakeholders Sub-component 3: Life Cycle Assessment and Sustainability Assessment
REFNo: SS1627ES

Goal of the SophiA Project: To bring environmental, economic, social and health benefits, creating new business and job opportunities through new technological solutions; to support African countries to pursue sustainable pathways of development through a low-carbon, climate resilient and green growth trajectory, leapfrogging fossil fuels and high GWP refrigerant technologies; and to improve the quality of life of populations through better treatment and working conditions in rural and remote health facilities in Africa.

Specific Objectives of the Proposed Studies:
i) To assess the needs from several health stations in order to identify and match the most significant and suitable health station which can be served by one SophiA system, considering different uses, replicability, cost and constraints as pertains energy consumption and solar radiation.
ii) To assess the level of acceptance of the SophiA technological solutions by the relevant stakeholders including beneficiary communities, local leaders, health care providers and managers, district officials, and national level decision makers/policy makers.
iii) To conduct a Life Cycle Assessment (LCA) to evaluate the different environmental impacts and calculate the CO2 emissions for each of the SophiA technology: solar thermal, solar PV, thermal storage, electrical storage, ice storage, refrigerators).
 Uganda 2023-03-24 2:04:40 2026-03-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Nasuuna Michelle
ID:
The Epidemiology of Chronic Kidney Disease among young people living with HIV in Uganda
REFNo: HS2578ES

1. To describe the prevalence of CKD among YPLHIV in SSA. 2. To compare the prevalence and associated factors of CKD diagnosed with cystatin C or creatinine-based estimates among YPLHIV in Uganda.
3. To describe the comorbidities associated with CKD among YPLHIV in Uganda.
Uganda 2023-03-22 15:08:26 2026-03-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Bangirana
ID:
Blood-Biomarkers and Risk Factors of Acute Brain Injury associated with Neurodisability in Ugandan Children (BRAIN-Child)
REFNo: HS2628ES

Determine if elevated brain injury biomarkers in pediatric TBI correlate with post-discharge mortality or neurocognitive impairment (NCI) and health-related quality of life outcomes at 6-month follow-up,Determine if biomarkers and risk factors of brain injury elevated in pediatric CM are elevated in pediatric TBI,
 Uganda 2023-03-21 3:29:20 2026-03-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon  Kasasa
ID: UNCST-2021-R012861
 A National Survey to Determine the Prevalence of Latent and Active Tuberculosis, COVID-19 and HIV Among Prisoners and Prisons Staff in Uganda Prisons
REFNo: HS2373ES

Overall objective
To determine the burden and associated factors of TB, COVID-19, and HIV among inmates and staff in Uganda prisons in order to generate evidence that will inform future interventions.
Primary objectives
i. To estimate the prevalence and associated factors of LTBI among inmates and staff in the Uganda prisons.
ii. To determine the prevalence and associated factors of active TB disease among inmates and staff in Uganda prisons.
iii. To determine the current burden of COVID-19 among prisoners and staff using an integrated TB and COVID-19 screening and testing approach.
iv. To establish the burden of past COVID-19 infection among prisoners and staff in Uganda prisons.
v. To determine the prevalence of HIV among inmates and staff in Uganda prisons.
vi. To determine HIV program achievement and gaps in the Uganda Prisons in reference to the UNAIDS targets for HIV testing, positive individuals who are on treatment, and PLHIV with suppressed viral load (95-95-95).

Uganda 2023-03-21 3:23:05 2026-03-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moreen Kabarungi
ID:
A FRAMEWORK TOWARDS THE IMPROVEMENT OF ADOPTION OF BLENDED LEARNING IN HIGHER EDUCATIONAL INSTITUTIONS CASE STUDY OF SOUTH WESTERN UGANDA.
REFNo: SS1665ES

The main objective of this study is to develop a framework to support the adoption of blended learning in higher educational institutions in south western Uganda.

The specific objectives are;
1. To establish the strengths, weaknesses and elicit the requirements of the existing blended learning frameworks and their level of usage and satisfaction in higher educational institutions.
2. To design a framework that supports the adoption of blended learning in higher educational institutions.
3. To evaluate the feasibility, acceptability and usage of the designed framework of blended learning in higher educational institutions.

 Uganda 2023-03-21 3:19:16 2026-03-21 Social Science and Humanities Non-Clinical Trial Degree Award
Tonny Ssekamatte
ID: UNCST-2022-R010961
 Understanding the barriers and facilitators to access and utilisation Sexual and Reproductive Health services among vulnerable/marginalized adolescents and young people in Uganda
REFNo: SS1673ES

To investigate the barriers and facilitators to access and utilisation Sexual and Reproductive Health services among vulnerable/marginalized adolescents and young people in Uganda ,Examine the role of social media/other sources in the spread of information and/or disinformation and how it potentially influences access to and use of SRH services.,Examine the role of social norms in influencing the use/non-use of SRH services among the populations of interest:,Explore the barriers and facilitators to accessing SRH services among vulnerable/marginalized 15–24-year-old adolescents and young people.,
 Uganda 2023-03-21 3:16:17 2026-03-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Annet Nanungi Kabuye
ID:
An mhealth framework for cancer surveillance in Uganda
REFNo: HS2695ES

To develop an mhealth data framework for cancer surveillance in Uganda.,
 Uganda 2023-03-21 3:06:26 2026-03-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth (Betsy) Ness-Edelstein Ann
ID:
Cooperative Development Program Evaluation
REFNo: SS1664ES

Assess how the specific work of Health Partners in Uganda is contributing to the overall program objectives,● Contribute to the evidence base on effective cooperative development approaches.,● Identify the assumptions or gaps in the project’s design or management approach to help inform a new project design,● Illuminate ways in which the entire project is making progress toward the stated Project Purpose or not,
 USA 2023-03-21 3:04:41 2026-03-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Edward Mokooza Kibikyo
ID: UNCST-2020-R014923
 Understanding Barriers and Facilitators to Establishing Palliative Care Units at Hospitals in Uganda.
REFNo: SS1510ES

4. To identify the facilitators of establishing palliative care units in hospitals in Uganda. ,3. To describe barriers to the establishment of palliative care units in hospitals in Uganda.,2. To document the functionality of existing PC units in hospitals in Uganda. ,1. To determine the proportion of public and private hospitals with PC units.,
 Uganda 2023-03-16 13:06:27 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Zhubin Chen
ID:
The Impact of Social Health Insurance on the Incentives of Health Care Providers in East Africa: A Mixed-methods Approach
REFNo: SS1574ES

1.1 Describe how social health insurance functions and how health care providers respond to the economic incentives of social health insurance in Rwanda, Kenya, and Uganda 1.2 Pose hypotheses based on 1.1 and test them empirically using nationally representative data 2. Follow different institutional actors (ministry of health, health facilities, NGOs, and community organizations) and describe how they perceive the function of social health insurance in Rwanda, Kenya, and Uganda 3. Compare the impact mechanism of social health insurance in Rwanda, Kenya, and Uganda and document how the impact evolves on different paths and at different stages towards UHC
China 2023-03-16 13:04:14 2026-03-16 Social Science and Humanities Non-Clinical Trial Degree Award
Peace Tumuheki Buhwamatsiko
ID:
Experiences of students combining work and study at Ugandan universities
REFNo: SS1646ES

To explore experiences of students who combine work and study at both private and public universities in Uganda with a view of making recommendations that will contribute to improving their university education experience and promote inclusive lifelong learning agenda in higher education,To explore and examine the suitable academic and administrative supports for students combining work and study,To explore the classroom learning experiences of students who combine work and study,To uncover the motivations underlying the decision to combine work and study at university and the associated benefits and challenges,
 Uganda 2023-03-16 13:02:52 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 Implementation of an eRegistry Enabled Transition from Four to Eight Antenatal Care Contacts - a Cluster-Randomized Controlled Trial in Mukono and Buikwe, Uganda (eReg4ANC8)
REFNo: HS2662ES

III. Undertake a cRCT of the new ANC8 vs. the current ANC4 schedule for low-risk pregnancies, to estimate its impact on quality of care, health, and satisfaction.,II. To assess and respond to factors across the i-PARIHS and COM-B domains to guide the facilitation of feasibility, acceptability, fidelity, and effectiveness of implementation of digitally enabled ANC8 at scale. ,I. To assess and respond to factors across the PARIHS and COM-B domains to guide the facilitation of feasibility, acceptability, fidelity, and effectiveness of the implementation of DHIS2 eRegistries for ANC at scale. ,
 Uganda 2023-03-16 13:01:11 2026-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victoria Ndyanabangi
ID: UNCST-2021-R012645
 IMPAACT 2036: Phase I/II Study of the Safety, Tolerability,Acceptability, and Pharmacokinetics of Oral and Long-ActingInjectable Cabotegravir and Rilpivirine in Virologically SuppressedChildren Living with HIV-1, Two to Less Than 12 Years of Age, DAIDSStudy ID #38932 IND # 138754
REFNo: HS2688ES

To propose the weight band dosing of oral cabotegravir (CAB) + oral rilpivirine (RPV)followed by long-acting injectable CAB (CAB LA) + long-acting injectable RPV (RPV LA)in children living with HIV-1, and to describe participant choice and experience with theregimen with or without an oral lead-in period.
To describe the repeat-dose pharmacokinetics of CAB + RPV (oral and injectable)through Week 24
To assess the safety of the oral lead-in of CAB + RPV, and the safety of CAB + RPV (oraland injectable) through Week 24
To assess the safety of CAB + RPV (oral and injectable) through Weeks 48 and 72
To describe the repeat-dose pharmacokinetics of injectable CAB LA + RPV LA throughWeeks 48 and 72
To assess the maintenance of viral suppression of CAB + RPV (oral and injectable)through Weeks 24, 48, and 72
To evaluate the tolerability and acceptability of injectable CAB LA + RPV LA throughWeeks 24, 48, and 72
To describe HIV-1 genotypes and phenotypes for children who experience virologicfailure during study treatment
To assess immunologic activity of CAB + RPV (oral and injectable) through Weeks 24,48, and 72
To describe tolerability and acceptability of 48 weeks of CAB + RPV (oral and injectable)and 44 weeks of CAB LA + RPV LA (injectable only)
To describe the safety and repeat-dose pharmacokinetics of 48 weeks of CAB + RPV(oral and injectable) or 44 weeks of CAB LA + RPV LA (injectable only)
To describe the maintenance of viral suppression and immunologic activity of 48 weeks ofCAB + RPV (oral and injectable) or 44 weeks of CAB LA + RPV LA (injectable only)
To describe HIV-1 genotypes and phenotypes for children who experience virologicfailure during 48 weeks of CAB + RPV (oral and injectable) or during 44 weeks of CABLA + RPV LA (injectable only)
To characterize long-term safety and washout PK through 48 weeks after permanentdiscontinuation of injectable CAB LA + RPV LAV LA
To characterize PK of CAB + RPV oral formulations when dispersed in liquid vs. directly ingested (Weight Bands 3, 4 and 5)
 Uganda 2023-03-16 12:55:20 2026-03-16 Medical and Health Sciences Clinical Trial Non-degree Award
Charles Batte
ID: UNCST-2021-R013587
 The impact of COVID-19 on school enrolment and mental health of children in the Manafwa Watershed area in Uganda.
REFNo: HS2725ES

To assess the coping strategies of school-going children in the Manafwa Watershed area during the COVID-19 pandemic.,To assess the post-lockdown mental health status of school-going children in the Manafwa Watershed area. ,To evaluate the effects of COVID-19 lockdown on school enrolment of children in the Manafwa Watershed area.,To assess the impact of COVID-19 and its associated restrictive measures on school enrolment and mental health of children in a disaster-prone area, Manafwa Watershed area, in Eastern Uganda.,
 Uganda 2023-03-16 12:51:27 2026-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jack Richardson Lloyd
ID:
The role of social play in the development of wild mountain gorillas in Bwindi Impenetrable National Park, Uganda
REFNo: NS490ES

(1) determine how biological, ecological, and social factors influence amount of time spent in social play.
(2) examine how structural components of play (asymmetry, dominance, play
partnerships, play type) can differentiate between functions.
(3) investigate proposed trade-offs and developmental outcomes of social play.
UK 2023-03-16 12:48:10 2026-03-16 Natural Sciences Non-Clinical Trial Degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 GS-US-380-1474: A Phase 2/3, Open-Label Study of the Pharmacokinetics, Safety, and Antiviral Activity of the GS-9883/Emtricitabine/Tenofovir Alafenamide (GS-9883/F/TAF) Fixed Dose Combination (FDC) in HIV-1 Infected Adolescents and Children
REFNo: HS2708ES

This is a multisite, multi-cohort study that aims to recruit subjects in four weight-based cohorts (i.e. Cohort 1, 2, 3 and 4), with each cohort having specific objectives aligned with it. Baylor Uganda site will recruit subjects in cohort 4 with is further subdivided in 4 weight-based sub-groups. The study objectives in relation to the Cohort 4 are as follows;
Cohort 4
Group 1:
The primary objective of this study is:
• To evaluate the safety and tolerability of B/F/TAF 30/120/15 mg (administration of 2 B/F/TAF 15/60/7.5 mg FDC TOS) once daily through Week 24 in HIV-1 infected, virologically suppressed children ≥ 2 years of age weighing ≥ 14 to < 25 kg who are unable to swallow tablets
The secondary objectives of this study are:
• To evaluate the safety and tolerability of B/F/TAF 30/120/15 mg (administration of 2 B/F/TAF 15/60/7.5 mg FDC TOS) once daily through Week 48 in HIV-1 infected, virologically suppressed children ≥ 2 years of age weighing ≥ 14 to < 25 kg who are unable to swallow tablets

• To evaluate the antiviral activity of B/F/TAF 30/120/15 mg (administration of 2 B/F/TAF 15/60/7.5 mg FDC TOS) once daily through Weeks 24 and 48 in HIV-1 infected, virologically suppressed children ≥ 2 years of age weighing ≥ 14 to < 25 kg who are unable to swallow tablets
Group 2:
The primary objectives of this study are:
• To evaluate the steady state PK of BIC and TAF and confirm the dose of B/F/TAF 7.5/30/3.75 mg (administration of 2 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 10 to < 14 kg

• To evaluate the safety and tolerability of B/F/TAF 7.5/30/3.75 mg (administration of 2 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Week 24 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 10 to < 14 kg
The secondary objectives of this study are:
• To evaluate the safety and tolerability of B/F/TAF 7.5/30/3.75 mg (administration of 2 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Week 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 10 to < 14 kg

• To evaluate the antiviral activity of B/F/TAF 7.5/30/3.75 mg (administration of 2 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Weeks 24 and 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 10 to < 14 kg.
Group 3:
The primary objectives of this study are:
• To evaluate the steady state PK of BIC and TAF and confirm the dose of B/F/TAF 3.75/15/1.88 mg (administration of 1 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 6 to < 10 kg

• To evaluate the safety and tolerability of B/F/TAF 3.75/15/1.88 mg (administration of 1 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Week 24 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 6 to < 10 kg.
The secondary objectives of this study are:
• To evaluate the safety and tolerability of B/F/TAF 3.75/15/1.88 mg (administration of 1 B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Week 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 6 to < 10 kg

• To evaluate the antiviral activity of B/F/TAF 3.75/15/1.88 mg (administration of 1 × B/F/TAF 3.75/15/1.88 mg FDC TOS) twice daily through Weeks 24 and 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 6 to < 10 kg.
Group 4:
The primary objectives of this study are:
• To evaluate the steady state PK of BIC and TAF and confirm the dose of B/F/TAF 1.88/7.5/0.94 mg (administration of 1 B/F/TAF 1.88/7.5/0.94 mg FDC TOS) twice daily in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 3 to < 6 kg.

• To evaluate the safety and tolerability of B/F/TAF 1.88/7.5/0.94 mg (administration of 1 B/F/TAF 1.88/7.5/0.94 mg FDC TOS) twice daily through Week 24 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 3 to < 6 kg
The secondary objectives of this study are:
• To evaluate the safety and tolerability of B/F/TAF 1.88/7.5/0.94 mg (administration of 1 B/F/TAF 1.88/7.5/0.94 mg FDC TOS) twice daily through Week 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 3 to < 6 kg

• To evaluate the antiviral activity of B/F/TAF 1.88/7.5/0.94 mg (administration of 1 B/F/TAF 1.88/7.5/0.94 mg FDC TOS) twice daily through Weeks 24 and 48 in HIV-1 infected children ≥ 1 month of age, on ARV treatment or treatment naive, weighing ≥ 3 to < 6 kg

 Uganda 2023-03-16 12:47:17 2026-03-16 Medical and Health Sciences Clinical Trial Non-degree Award
Bjorn Van Campenhout -
ID: UNCST-2020-R014080
 Increasing Adoption and Varietal Turnover of Seed: Consumer and Producer Side Interventions
REFNo: SS1657ES

The study will be implemented through a cluster randomize control trial, where a sample of treatment villages (clusters) will receive producer side treatments (free seed trial packs or discounted seed trial packs of a poorly adopted improved maize variety, Bazooka) while other treatment villages will receive a consumer side intervention involving cooking and tasting demonstration of maize from the improved variety. However, in both treatment and control groups, we will inform farmers about the existence of the improved seed variety and the benefits of using them, to be able to isolate the effect of the trail pack from merely knowledge effects.
 Belgium 2023-03-16 12:43:52 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jennifer  Kealy
ID:
Community Engagement in Paediatric Biobanking Governance in Uganda.
REFNo: SS1651ES

The aim of this study is to provide IARC and the Ugandan Government with actionable recommendations concerning the development of paediatric biobanking guidelines. The primary objective is to identify the key ethical issues/concerns for researchers, laboratory staff, and health authorities in Uganda, specifically related to public trust in biobanking, and how trust/ trustworthiness could be addressed in paediatric biobanking governance as well as how the community might be engaged.
• Does it hold true that trust/ trustworthiness is contextual and that effectively would preclude any harmonisation of guidelines for biobanking? Or is there any common ground on which to build global /international guidelines,
• What are the gaps in biobanking in Uganda, particularly with respect to paediatric biobanking and,
• How can Uganda create paediatric biobanking guidelines that reflect the needs identified by communities and what would this look like, and,
• How can biobanks show they are trustworthy through their governance and what does that look like to Uganda? Is it sufficient to be transparent and accountable or are other cultural/economic/religious/aspects that parents consider in their assessment of trust in a biobank?
• How can ethical considerations related to biobank governance be addressed in an inclusive, collaborative and deliberative manner

 USA 2023-03-16 12:41:09 2026-03-16 Social Science and Humanities Non-Clinical Trial Degree Award
Jennifer Verdolin
ID:
Establishing a Long-Term Behavioral and Ecological Monitoring Research Program in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park
REFNo: NS500ES

1) Understand the factors contributing to within and between group variability in parasite infection and transmission; 2) Characterize the diet of mountain gorillas across different habitats in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 3) Explore habitat use and spatial dynamics of mountain gorillas in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 4) Collaborate with UWA to yield insights critical for the protection and management of mountain gorillas and other species in Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park; 5) Characterize the biodiversity of Bwindi Impenetrable Forest National Park and Mgahinga Gorilla National Park, including genomics of multiple species using opportunistically collected fecal samples. These species include but would not be limited to forest elephants and pangolins.
USA 2023-03-16 12:39:44 2026-03-16 Natural Sciences Non-Clinical Trial Non-degree Award
Florence Kyoheirwe Muhanguzi
ID: UNCST-2021-R002777
 Building women smallholder farmers’ empowerment and adaptive capacities: A pathway to enhancing women’s resilience to climate change in Uganda
REFNo: SS1660ES

General objective
● To strengthen the empowerment and adaptive capacity of women smallholder farmers in the cattle corridor of Uganda using gender transformative approaches.

Specific objectives
1. Establish women smallholder farmers’ levels of empowerment and adaptive capacities to the effects of climate change;
2. Assess the social cultural gender norms, economic and political trade-offs and barriers to empowerment and climate adaptation by women smallholder farmers;
3. Design and test a mix of gender transformative climate change adaptation innovations that are effective in enhancing women smallholder farmers’ empowerment and resilience to the effects of climate change.
4. Advocate for policies and practices that enhance women smallholder empowerment and adaptive capacities to climate change shocks.

 Uganda 2023-03-16 12:37:54 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Phase IIa Proof of Concept, Multicenter, Randomized, Open-label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of the Combination M5717 plus Pyronaridine Administered once Daily for 1 or 2 Days to Adults and Adolescents with Acute Uncomplicated Plasmodium falciparum Malaria
REFNo: HS2736ES

To evaluate the safety and
tolerability of the M5717-
pyronaridine combination in
adult participants with acute
uncomplicated malaria due to
P. falciparum.
Secondary.
o describe the clinical efficacy
of the M5717-pyronaridine
combination in adult participants
with acute uncomplicated
malaria due to P. falciparum
 Uganda 2023-03-16 12:35:56 2026-03-16 Medical and Health Sciences Clinical Trial Non-degree Award
Charles Masembe Kikubo
ID: UNCST-2019-R001092
 The Dispersal of Antibiotic Resistance and Antibiotics in Water Ecosystems and Influence on livestock and Aquatic wildlife (PAIRWISE)
REFNo: A240ES

i) To investigate the dispersal of Antibiotic Resistant Bacteria (ARB), Antibiotic Resistant Genes (ARG) and Antibiotics (ATB) in surface waters downstream of WWTPs ii) To investigate the carriage of ARB and ARG in livestock linked to surface waters influenced by WWTPs iii) To ascertain the role of aquatic birds in dispersal of ARB and ARG
Uganda 2023-03-09 23:54:51 2026-03-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Francis Garuzooka John
ID:
Investment practices of persons with a disability in informal microfinance groups in Uganda
REFNo: SS1617ES

1. Examine the attitudes of persons with a disability regarding investment, saving and borrowing from VSLAs and ROSCAs in selected districts in Uganda. 2. Analyse what influences the persons with a disability’ investment choices as individuals and members of groups (Revised as: Analyse what influences persons with disabilities’ investment choices as individuals and as members of groups.) 3. Explain how persons with a disability acquire the knowledge and skills they use while investing resources obtained from VSLAs and ROSCAs. 4. Describe the experiences that persons with a disability have regarding investment of loans obtained from VSLAs and ROSCAs in selected districts in Uganda.
Uganda 2023-03-09 23:52:14 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bonniface Oryokot
ID:
Adaptation and Evaluation of the Operation Triple Zero (OTZ) model to improve Retention and HIV viral suppression among the Adolescents Living with HIV in TASO Uganda using the RE-AIM framework.
REFNo: SS1610ES

• To implement and test the adapted OTZ intervention from January 2023 to end of August 2023.,• To adapt and design the OTZ model to the TASO Uganda context,• To determine the barriers and facilitators to Retention and VLS,• To improve health outcomes among CALHIV in selected TASO Uganda COEs.,
 Uganda 2023-03-09 23:48:16 2026-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
 Observational study on management of post-partum haemorrhage at Kawempe National Referral Hospital (REBOA-PPH baseline study)
REFNo: HS2730ES

To suggest a customized training to improve PPH management in a large referral hospital in Uganda,To identify specific areas of potential improvements in PPH management,To describe the actions taken in the process of managing PPH among mothers admitted to KNRH,To describe the current management of severe PPH with timelines from identification until bleeding is controlled,To map the occurrence of severe PPH among birthing mothers admitted at Kawempe National Referral Hospital (KNRH),The aim of this study is to map the occurrence of severe post-partum haemorrhage (PPH) and its current management and to identify potential improvements in the management of severe PPH in a large referral hospital in Uganda. ,
 Uganda 2023-03-09 23:43:20 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EZRA BYAKORA
ID: UNCST-2022-R009194
 Investigating the enhancement of Nile tilapia breeding in Uganda through integration of modern aquaculture breeding and genetics tools
REFNo: A269ES

1)Support NAGRC&DB to improve its Nile tilapia breeding program via establishing individual fish identification and phenotyping system.
2)Investigate genetic health and diversity of Uganda’s farmed Nile tilapia breeding population in comparison to their wild relatives in the three major lakes (L. Victoria, L. Kyoga and L. Albert) in Uganda.
3)Estimate genetic parameters of key production traits (including growth rate, body length and harvest weight).
4)Identify genomic regions associated with production traits.
5)Investigate potentials of integrating genomic tools into selective breeding for improving Nile tilapia in Uganda.

 Uganda 2023-03-09 23:41:58 2026-03-09 Agricultural Sciences Non-Clinical Trial Non-degree Award
Carolyn Pelnik
ID:
School Management and Re-Enrolling Dropouts: Experimental Evidence from Schools in Rural Uganda
REFNo: SS1656ES

Which version of the program is more cost-effective in terms of gains to student learning: an intervention that assigns highly qualified university graduates to partner with community members to implement enrollment and remedial education activities, or an intervention where enrollment and remedial education activities are executed by community members alone? ,What is the effect of a school management intervention targeted towards the head teacher on school inputs (administrator time use and other measures of school functionality such as teacher attendance) and outputs (enrollment and learning, as measured by literacy and numeracy test scores)?,
 USA 2023-03-09 23:39:42 2026-03-09 Social Science and Humanities Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
 A Phase 2/3, Multicenter, Open-label, Multicohort Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected, Virologically Suppressed Pediatric Participants.
REFNo: HS2646ES

The primary objective of this study is to confirm the dose of ATV/co or DRV/co in HIV-1 infected pediatric participants, to confirm the dose of F/TAF in HIV-1 infected pediatric participants and to evaluate the safety and tolerability these medications.
 Uganda 2023-03-09 23:33:04 2026-03-09 Medical and Health Sciences Clinical Trial Non-degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
 Developing an STI partner notification services delivery intervention in southwestern, rural Uganda.
REFNo: HS2720ES

Explore facilitators and barriers to task-shifting delivery models for STI partner notification among healthcare workers, administrators, and potential patients. Also to develop a novel STI partner notification services delivery intervention for Uganda and similar settings.
USA 2023-03-09 22:41:48 2026-03-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph  Kampumure
ID:
FINANCIAL LITERACY, SELF-EFFICACY AND FINANCIAL INCLUSION AMONG WORKING WOMEN IN UGANDA
REFNo: SS1474ES

i) Establish the effect of financial literacy on financial inclusion among working women in Uganda. ii) Establish the effect of financial literacy on self-efficacy among working women in Uganda. iii) Determine the effect of self-efficacy on financial inclusion among working women in Uganda. iv) Determine the effect of self-efficacy on the connexion between financial literacy and financial inclusion among working women in Uganda.
Uganda 2023-03-07 11:05:55 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Jiseon Chang
ID:
Empowering Developing Countries: Combating Misinformation and Correcting (Mis)perceptions of Foreign Aid
REFNo: SS1545ES

Understand how and when are perceptions of aid created
 South Korea 2023-03-07 11:04:27 2026-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Patricia Ndugga
ID: UNCST-2022-R009605
 Parent-adolescent communication on sexual and reproductive health in Kyotera border district, Central Uganda
REFNo: HS2702ES

The main objective of this study is to investigate the practice of SRH communication between parents and adolescents in Kyotera district, Central Uganda., 1. To determine the prevalence and factors associated with parent adolescent communication about SRH in Kyotera district. A cross-sectional survey for both parents and children will be conducted to establish the proportion of parents / children who discuss SRH issues, 2. Explore the approaches to, content and frequency of SRH communication between parents and adolescents in Kyotera., 3. To assess the community and district level stakeholders’ recommended strategies for improving communication of SRH between parents and adolescents.,
Uganda 2023-03-07 10:57:19 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 COVID-19 vaccine effectiveness and variants in Uganda: a test-negative case-control study with genetic sequencing (COVVAR)
REFNo: HS2672ES

Primary Objective To estimate vaccine effectiveness of licensed COVID-19 vaccines against laboratory-confirmed COVID-19 disease. Secondary Objectives 1. To identify circulating SARS-CoV-2 variants in Uganda. 2. To estimate vaccine effectiveness against specific SARS-CoV-2 variants identified by genetic sequencing. 3. To estimate vaccine effectiveness against severe COVID-19 disease. 4. To estimate effectiveness of COVID-19 vaccines against different SARS CoV-2 variants and different COVID-19 disease severities. Exploratory objective 1. To evaluate disease severity due to different circulating SARS CoV-2 variants
 Uganda 2023-03-07 10:53:48 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DENIS MUGIZI RWABIITA
ID:
Assessment of meat handler training interventions on hygiene and disease detection in Ugandan slaughterhouses and meat retail outlets
REFNo: A266ES

Use syndromic surveillance to understand the incidence and distribution of important animal and zoonotic disease in Uganda,Assess the impact of mobile training tool on meat inspector knowledge,Assess the impact of nudges on knowledge and practices and food contamination at pork retail,Assess the impact of a targeted meat handler training on the knowledge, attitudes, and practices of meat handlers in Uganda.,
 Uganda 2023-03-07 10:50:39 2026-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
 Understanding the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda - a quasi experiment
REFNo: HS2689ES

General objective: To understand the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda.

Specific objectives:
1. To determine the optimal performance based financial incentive incentive's structure required for improving the performance, motivation and retention of CHWs.

2. To explore the acceptability and perceptions of potential sustainability of CHWs financial compensation structure to various stakeholders, including the CHWs, and the CHW supervisors at the district and Ministry of Health.

3. To explore the perceived value and impact of financial incentives on CHW's job satisfaction, personal income and livelihood.
 UK 2023-03-07 10:40:31 2026-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
 Assessing Dementia and Frailty among Older Persons in selected rural districts in Eastern Uganda
REFNo: HS2693ES

Therefore, the aim this study is to determine the prevalence of frailty and dementia among older persons in rural Uganda. Specific aims of the study include:
Aim 1: To estimate the prevalence and factors associated with dementia among older persons in Uganda.
Aim 2: To estimate the prevalence and factors associated with frailty among older persons in Uganda.
Aim 3: To explore the experiences and perceptions of caregivers of older persons with dementia in Uganda.
In this study, we refer to point prevalence only.

Uganda 2023-03-07 10:36:00 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SONNY ASIMO
ID:
RISK FACTORS FOR FLUOROQUINOLONE RESISTANCE AMONG PATIENTS WITH SECOND LINE-DRUG RESISTANT TUBERCULOSIS EVALUATED AT THE UGANDA NATIONAL TUBERCULOSIS LABORATORY RefNo: CLARKE-2022-546
REFNo: HS2709ES

iii. To determine clinical factors associated with fluoroquinolone resistance in patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,ii. To characterize fluoroquinolone-resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,i. To determine the individual characteristics associated with fluoroquinolone resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,The study will determine the risk factors for fluoroquinolone resistance among patients with second-line drug resistant tuberculosis among previously evaluated samples in Uganda. ,
 Uganda 2023-03-07 10:25:46 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Perpetra Akite
ID: UNCST-2023-R008264
 Systematic study of insect fauna in selected sites in Uganda (Insect Systematic Project)
REFNo: NS494ES

To sample a broad geographic area, including some of the never-collected or poorly-collected sites to yield new species that will be valuable to the insect systematic community and inform their conservation management
 Uganda 2023-03-07 10:24:40 2026-03-07 Natural Sciences Non-Clinical Trial Non-degree Award
JOAN TUSABE
ID: UNCST-2021-R013942
 FACTORS INFLUENCING UPTAKE AND ADHERENCE TO PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) CARE AMONG REFUGEE HIV POSITIVE PREGNANT MOTHERS AGED 18 YEAS AND ABOVE IN KYANGWALI REFUGEE CAMP
REFNo: HS2711ES

1. To determine the level of uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

2. To determine factors associated with uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

3. To explore barriers and facilitators for uptake and adherence to prevention of mother to child transmission (PMTCT) services among HIV positive pregnant mothers aged 18 years and above in Kyangwali refugee camp


4. To determine strategies that can be put in place to improve uptake and adherence to prevention of mother to child transmission (PMTCT) among refugee HIV positive pregnant mothers in Kyangwali refugee camp?

 Uganda 2023-03-07 10:23:51 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Samson Udho
ID: UNCST-2021-R013728
 Respectful maternity care in childbirth among adolescents aged 14 to 19 years in rural northern Uganda: a mixed-method study
REFNo: HS2727ES

The objectives are to: 1. Determine the prevalence of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 2. Determine the predictors of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 3. Explore the experiences of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 4. Explore the drivers of D&A of adolescents aged by SBA during childbirth in public health facilities in rural northern Uganda.
 Uganda 2023-03-02 16:34:50 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
 Evaluating Mbarara University of Science and Technology (MUST) Internal Quality Assurance Mechanisms (IQAMs) on her Quality
REFNo: SS1629ES

General Objective
To evaluate MUST’s IQAMs on her quality using the IUCEA Model
Specific Objectives
1.To evaluate MUST’s IQAMs on the quality of Teaching and Learning
2.To examine MUST’s IQAMs on the quality of Research and Innovations
3.To assess MUST’s IQAMs on the quality of Community outreach

Uganda 2023-03-02 16:23:10 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 ESTABLISHMENT AND EVALUATION OF CAPRI CELLS IN UGANDA FOR ADOPTIVE CELL THERAPY
REFNo: HS2684ES

1. Evaluate the reproducibility of Cascade Primed Cells with Apheretic collected Autologous PBMCs in Uganda
2. Test the effect of the reproduced CAPRI cells on Lung and Cervical cancer cells in vitro

 Uganda 2023-03-02 15:39:34 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rachel Brathwaite
ID:
Assessing the Feasibility of Economic Approaches to Prevention of Substance Abuse among Adolescents
REFNo: HS2683ES

Aim 1. Examine the prevalence and consequences of ADU in a cohort of 200 AYLHIV (ages 18-24) seen at six (6) HIV clinics in southwestern Uganda.
Aim 2. Using a mixed methods approach, identify the multi-level (individual, interpersonal, community and structural) factors associated with ADU among AYLHIV.
Aim 3. Using a subset of the sample, explore the feasibility and short-term effects of a family-based economic empowerment intervention on ADU among AYLHIV.

 Trinidad and Tobago 2023-03-02 15:32:31 2026-03-02 Medical and Health Sciences Clinical Trial Non-degree Award
NALWANGA ROSEMARY
ID:
Towards reconstructing latitudinal and altitudinal temperature gradients from the Last Glacial Maximum to the Present – Development of a globally applicable palaeothermometry method based on luminescence
REFNo: NS487ES

Reconstruction of surface air temperatures over the past 20,000-30,000 years along an
Achieve a better understanding of atmospheric dynamics in the tropics during the transition
from the Pleistocene to the Holocene
altitudinal gradient (lapse rate) and comparison to currently measured temperatures
 Uganda 2023-03-02 15:14:46 2026-03-02 Natural Sciences Non-Clinical Trial Non-degree Award
Victoria Nambasa Prudence
ID: UNCST-2022-R008757
 Landscape Assessment To Understand Maternal Vaccine Pharmacovigilance In Uganda
REFNo: HS2680ES

Main objective
The aim is to conduct a rapid assessment gap analysis and stakeholder mapping for safety monitoring of vaccines used in pregnancy and potential for use of Electronic Medical Record (EMR) for sentinel site surveillance in Uganda for post licensure studies as well as current tetanus and COVID-19 vaccination. The results of the assessment will inform areas of focus for establishment of robust safety surveillance of novel maternal vaccination and vaccines that maybe administered during pregnancy in pandemic situations in the country.
Specific objectives
1. Map stakeholders involved in regulation, policy setting, collection and reporting of adverse events following maternal vaccination and their linkages
2. Understand the existing methods, tools, and information flow for collecting and flow of adverse event following maternal vaccination
3. Mapping of current Electronic Health Record and registries roll-out and how they interface with national drug safety reporting system especially in relation to maternal vaccination
4. To understand the Community views, and perceptions on vaccination and reporting of AE during maternal immunization

Uganda 2023-03-02 15:08:39 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edmund  Mugayehwenkyi Kenneth
ID:
Women Rise Together across the Lifecourse (Write-Life)
REFNo: SS1633ES

3. What do women need to address their health and wellbeing issues and to feel more empowered? ,2. How empowered are women feeling? Document levels of perceived empowerment among women across the lifecourse, from young women through middle aged, to older women as well and capture the varied experiences of women in varied socioeconomic, cultural and community situations.,1. How are women doing? Examine associations between work (both paid and unpaid) and health throughout the COVID-19 pandemic among women across the lifecourse.,
 Uganda 2023-03-02 14:46:12 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irumba Eleazar Paddy
ID:
The environmental stewardship by the church of Uganda in Albertine region- a case of Bunyoro-Kitara diocese.
REFNo: HS2675ES

4. To Explore the Theological Practices that the Church can use to enhance Environmental Stewardship in the Albertine Region.,3. To Establish the Relationship of Religious Teachings and Ethical Practices regarding Environmental Stewardship in the Albertine Region.,2. To Examine the role played by Church of Uganda in Environmental Stewardship in the Albertine Region,1. To investigate the current factors responsible for Environmental Degradation in the Albertine Region,
 Uganda 2023-03-02 14:04:06 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
 ASSESSMENT OF THE MAGNITUDE AND CORRELATES OF HIV STIGMA AND DISCRIMINATION AND ITS EFFECTS ON THE COUNTRY’S HIV RESPONSE
REFNo: HS2690ES

To describe how different groups are affected by HIV related stigma and discrimination especially the key populations. ,To identify factors that perpetuate or mitigate stigma as well as the actions (resilience) taken by PLHIV to mitigate the impact of stigma and discrimination,To assess the effect of stigma and discrimination on the country’s HIV response.,To describe trends in experience of stigma and discrimination among PLHIV over time (comparing 2013, 2019 and 2022).,To determine the prevalence and distribution of the modes (internal and external) of HIV related stigma and discrimination manifestations among PLHIV ,To assess the magnitude and correlates of HIV stigma and discrimination and its effects on the country’s HIV response ,
 Uganda 2023-03-02 14:02:36 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Mpairwe
ID: UNCST-2025-R017439
 Causes And MEchanisms foR non-atopic Asthma in children (CAMERA) Study
REFNo: HS2510ES

There is an urgent need for new and innovative research into the causes of non-atopic asthma (NAA), and the likely mechanisms involved. The objectives of this study are therefore to: I. investigate the causes of NAA in a variety of settings: high and low asthma prevalence, HICs and LMICs (Work Package 1 (WP1) II. investigate three possible mechanisms of NAA in these different settings, including the relative importance of neural mechanisms (Work Package 2 (WP2)) This intended scientific value of study is to provide key ground-breaking insights into the causes and mechanisms of the poorly-studied yet predominant non-atopic asthma phenotype because: (i) non-atopic asthma likely has different causes from atopic asthma, and these have been little studied to date in both high-income countries and low- and middle-income countries; (ii) non-atopic asthma likely involves different mechanisms, which require different treatments. This study is likely to show, in a variety of settings, that a substantial proportion of non-atopic asthma may involve different mechanisms, and will identify new directions and priorities for prevention, mechanistic research, and the development of new therapies
Uganda 2023-03-02 13:54:33 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Iddi  Matovu
ID:
HIV RISKS AND INFECTION AMONG ADOLESCENT GIRLS AND YOUNG WOMEN AGED 15-24 YEARS IN UGANDA: DEVELOPMENT OF AN HIV-RISK REDUCTION MODEL FOR CENTRAL REGION
REFNo: HS2554ES

1) To determine the influence of behavioral and biological practices on the HIV Infection among AGYW in the Central region, Uganda.2) To assess the influence of socioeconomic factors on behavioral and biological practices associated with HIV Infection among AGYW in Central region, Uganda.3) To analyze the influence of structural factors on behavioral and biological practices associated with HIV Infection among AGYW in Central region, Uganda.4) To develop a multilevel HIV-Risk reduction model to facilitate the delivery of appropriate HIV prevention services responsive to the particular needs of the AGYW aged 15–24 years in the Central region, Uganda.
 Uganda 2023-03-02 12:56:09 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Ritwika Sen
ID:
Supervision and Productivity Dynamics: Evidence from a Field (Work) Experiment
REFNo: SS1612ES

To examine the direct effects of the supervision of survey enumerators on their learning and individual performance., Examine the impact of supervision on the performance of employees through two distinct channels: monitoring and feedback.,
 India 2023-03-02 12:53:15 2026-03-02 Social Science and Humanities Non-Clinical Trial Degree Award
Diana  Ntamu Nandagire
ID:
Baseline survey for diverse and resilient livelihoods for youth and women from refugee and host communities in Isingiro and Lamwo districts
REFNo: SS1547ES

Main objective
To establish baseline status of the selected indicators for the Uthabiti project impact, outcome and outputs.


a)To provide initial values for the impact and outcome indicators disaggregated by gendered households as appropriate in the Uthabiti intervention areas, establishing target levels for improvements in these indicators over the three-year implementation period.

b)To provide more evidence to describe the prevailing conditions of the target communities or populations in terms of their socio-economic wellbeing and self-reliance and refine intervention. This will provide the consortium team a deeper understanding of the context to tailor the interventions as well understanding how well or not, the proposed theory of change aligns with the demonstrated need of the target population survey.


c)To provide Uthabiti baseline indicator values that can be compared with the endline indicator values to measure the level of changes and inform future programing,, and


d)To integrate gender and social inclusion throughout the review.

Uganda 2023-03-02 12:52:03 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
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