Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nsobya  Samuel
ID: UNCST-2021-R012265
Characterizing artemisinin resistance in severe malaria (CHARISMA): SMAART sub-study in Uganda
REFNo: HS3161ES

1. To characterize and compare the ex vivo drug susceptibilities of P. falciparum isolates from patients with and without severe malaria.
2. To characterize and compare genomic features of P. falciparum isolates infecting patients with and without severe malaria.
3. To assess whether presence of artemisinin partial resistance is associated with poor clinical outcomes in severe malaria patients.
4. To assess whether prior receipt of antimalarials is associated with artemisinin partial resistance in severe malaria patients

Uganda 2024-02-09 23:26:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Assessment of Feasibility, Acceptability and Effectiveness of Training Village Health teams On Household Air Pollution Using Teach BOX
REFNo: HS3723ES

1. To assess the feasibility and acceptability of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda.
2. To assess the effectiveness of training Village Health Teams on Household Air Pollution using TeachBox in Jinja district Uganda
Uganda 2024-02-09 23:25:22 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
DEVELOPMENT OF GEOSPATIO-TEMPORAL SURVEILLANCE AND CHARACTERISATION OF MALARIA IN THE CHANGING CLIMATIC CONDITIONS IN EASTERN UGANDA STUDY (GTS-MACS)
REFNo: HS3725ES

To determine the day three-parasite clearance rates of AL in children treated for malaria in Eastern and Northeastern Uganda. ,To determine whether there are any antimalarial drug resistance markers in Eastern and Northeastern Uganda. ,To describe geospatial-temporal patterns, determinants, and distribution of malaria with temperature, rainfall, and humidity patterns. ,Through geospatial-temporal surveillance, molecular studies and malaria parasite clearance rates, we shall characterise the overall epidemiology of malaria, any emergence of drug resistance and tolerance to the current antimalarials, respectively, in the era of changing climatic conditions in Eastern and Northeastern Uganda.,
Uganda 2024-02-07 15:13:15 2027-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
Tracer Study of Graduates with Disabilities: A Case of 2010-2020 PLE Candidates
REFNo: SS2196ES

iii. To establish the views of graduates with disability on the relevance of training, skills and competences for the type of work they are doing and corresponding gaps to be filled in future. ,ii. To find out whether the graduates of 2010 PLE and the proceeding years are gainfully employed indicating the location/organizations. ,i. To examine the retrospective views of the students with disabilities based on their career experiences ,
Uganda 2024-02-06 16:52:25 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Businge Alinaitwe
ID:
Effectiveness of a Family-Centered Support Intervention on Treatment Adherence Among Tuberculosis Patients in Jinja, Uganda
REFNo: HS3583ES

General Objective To determine the effectiveness of a family-centered support TB (FaCeTB) intervention in improving adherence to TB treatment among patients receiving care from treatment centers in Jinja district, Eastern Uganda., Specific objectives To explore perspectives of patients, family caregivers and health care providers regarding involvement of family members in TB treatment adherence To determine the level of family support received by TB patients in Jinja district, Eastern Uganda. To evaluate the effect of the FaCeTB intervention on the level of TB treatment adherence among patients in Jinja district, Eastern Uganda. To examine the level of treatment adherence among patients before the implementation of a family-centered support TB (FaCeTB) intervention in Jinja district, Eastern Uganda.
Uganda 2024-02-06 16:51:27 2027-02-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Daniel Hill
ID:
Inclusive Coffee Value Chains – understanding coffee grower preferences and participation in specialty and commodity coffee value chains in the Kapchorwa District, Uganda.
REFNo: SS2312ES

To identify and measure coffee farmer preferences and participation in specialty and commodity coffee value chain in the Kapchorwa District, Uganda, to identify whether value chains are inclusive, identify how to improve inclusion of these value chains, and identify how farmers can derive more value from inclusion.
Australia 2024-02-06 16:48:36 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Mayito
ID: UNCST-2019-R000490
Combatting Antimicrobial Resistance in Uganda: A Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes
REFNo: HS3690ES

To estimate the annual economic burden of AMR in Uganda using the cost-of-illness approach,To use Machine Learning Algorithms to develop predictive models for clinical outcomes of patients with infectious syndromes due to resistant pathogens,To evaluate the trends in antibiotic use using annual antibiotic and point prevalence survey data collected at nine RRHs over a five year period,To build a dynamic AMR/AMUC Data Warehouse to support research in AMR and AMUC to inform AMR related interventions and public health policy ,
Uganda 2024-02-06 16:46:26 2027-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Judith Arinaitwe
ID:
Exploring the Impact of Practices in Human Resource Development and Information Technology Use on Academic Staff performance in Bishop Stuart University
REFNo: SS2296ES

To examine how the interactions between practices in human resource development, information technology use, and academic staff performance at Bishop Stuart University shape overall performance outcomes.,To examine the utilization and integration of information technology (IT) tools and systems among academic staff at Bishop Stuart University.,To assess the current state of practices in human resource development (HRD) among academic staff at Bishop Stuart University.,The purpose of the study is to explore the impact of practices in human resource development and information technology use on academic staff performance at Bishop Stuart University.,
Uganda 2024-02-06 16:45:37 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Peter Kibira
ID: UNCST-2020-R014668
Advancing Understanding and Measurement of Infertility and Related Fear and Stigma in Uganda
REFNo: HS3624ES

Improve population-level infertility prevalence estimation by evaluating infertility measurement model assumptions in Uganda. (this was implemented as part of the PMA 2022 survey),Identify dimensions of infertility stigma and fear among women in Uganda.,Understand Ugandan women’s and men’s perceptions, fears, and experiences of infertility and its related stigma,to address these knowledge gaps by improving the field’s understanding of infertility levels, stigma, and fears in Uganda and sub Saharan Africa,
Uganda 2024-02-06 16:44:24 2027-02-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MIRIA NYANGOMA
ID:
PROCUREMENT RISK MANAGEMENT AND LOCAL GOVERNMENT PERFORMANCE IN UGANDA:A CASE STUDY OF KANUNGU DISTRICT LOCAL GOVERNMENT
REFNo: SS2317ES

To establish the relationship between procurement risk treatment decision and performance of Kanungu District Local Government,To assess the relationship procurement risk monitoring and Performance of Kanungu District Local Government,To analyze the effect procurement risk assessment on Performance of Kanungu District Local Government,To examine the influence of procurement risk identification on performance of Kanungu District Local Government,To examine the relationship between procurement risk management and Local Government performance in Uganda,
Uganda 2024-02-06 16:41:06 2027-02-06 Social Science and Humanities Non-Clinical Trial Degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
Psychometric properties analysis of UACE Biology 2022, 2020, 2018, 2015 and 2014: focus on item difficulty, distractor effectiveness and discrimination indices.
REFNo: SS2275ES

iii. To examine the difference between the distractor efficiency of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,ii. To examine the difference between the index of discriminating power of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,i. To examine the difference between the difficulty indices of the UACE Biology examination items of 2022, 2020, 2018, 2015 and 2014,
Uganda 2024-02-06 16:39:21 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
Implementation of the New Competence-Based Curriculum in Lower Secondary School on Pre-Vocational Education in Uganda: Focus on School Readiness.
REFNo: SS2278ES

iii. To explore the challenges experienced in the implementation of the competency-based teaching and learning by both teachers and students. ,ii. To examine the assessment approaches under the competence-based teaching and learning of the new Lower Secondary Curriculum. ,i. To assess the understanding of competence-based teaching and learning of the new Lower Secondary Curriculum by teachers and students. ,
Uganda 2024-02-06 16:34:04 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tonny Muzaale
ID: UNCST-2023-R006443
Prevalence of Examination Malpractice at Uganda Certificate of Education: Challenges and Legal Implications
REFNo: SS2268ES

iii. To state the legal implications of examination malpractices and best practices for the enforcement of new UNEB Act 2021,ii. To examine the challenges faced by the examining body in curbing the vice in Uganda at UCE,i. To examine the extent to which examination malpractice prevails at UCE in Uganda,
Uganda 2024-02-06 16:31:57 2027-02-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sandrine Perrot
ID: UNCST-2019-R001546
The Bureaucratisation of Legal Identities in colonial and post-colonial Uganda: A Socio-History of State Registration and Documentation of Individuals
REFNo: SS2227ES

My main objective is to generate original insights on the construction of bureaucratic knowledge and techniques of identification and their impact on state construction and practices of citizenship in Uganda. Our goal is to
1. Identify the (un)favourable contexts for the introduction of identification policies
2. Map the players involved in identification over time
3. Highlight the changes in the instruments of identification
4. Examine the circulation of these practices
5. Observe the impact of state identification and registration on the practices of citizenship and the relation to the state
At this stage of my research, I would like to focus on three non-exclusive lines of enquiry: the debate surrounding the first identity cards during late colonialism; the documentation of non-indigenous people, and in particular the citizenship crisis of Asians in the 1960s and 1970s; and finally, the intense periods of identification during electoral periods, and more specifically the processes of voter registration.

France 2024-02-05 13:28:32 2027-02-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Koichiro Watanabe
ID:
Nutrition Improvement and Livelihood Empowerment (NILE) impact study protocol: A cluster-randomized multi-level multisectoral intervention to improve nutrition in Uganda
REFNo: HS3566ES

The study aims to demonstrate the extent to which dietary diversity for women and young children are increased and undernutrition reduced among the intervention versus comparison areas. The findings of the evaluation study will be used to inform the government of Uganda and partners the effectiveness of the programme and to support learning.

Specific objectives of the study
• To evaluate impact by gathering, analysing and synthesising evidence to determine whether the multi-sector nutrition project results in improved nutrition status and dietary diversity among pregnant and lactating women, adolescents and children.

• To evaluate the quality of programme implementation and to inform refinements to intervention design and delivery.

• To understand the mechanisms of change by which the project activities impact key outcomes and nutritional status of children.

• To examine impact of economic empowerment to nutrition outcomes and food security

Japan 2024-02-05 13:26:35 2027-02-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon Owani Olok
ID:
Supporting Nile tilapia production through the introduction of modern genomic and breeding tools for indigenous farmed strains in Uganda
REFNo: A388ES

1. Introducing individual fish identification tools to OWANMWAN Aquaculture Limited’s Nile tilapia hatchery. This will be through the introduction of affordable T-bar anchor tags. This will allow individual fish phenotype recording and evaluation as a selection candidate.
2. Genetic assessment of OWANMWAN Aquaculture Limited’s Nile tilapia breeding sub-populations (strains), to establish genetic diversity, inbreeding level and genomic admixture within and between the strains.
3. Quantitative genetic and phenotypic (mainly growth rate) characterization of the Nile tilapia strains currently maintained at OWANMWAN Aquaculture Limited hatchery as broodstock.
4. Genomic evaluation of OWANMWAN Aquaculture Limited’s current broodstock to evaluate genetic diversity and inbreeding rate of the three strains at the hatchery.
5. Establishing a genomics-informed diverse Nile tilapia founder breeding stock for subsequent selective breeding.
6.Identifying genomic regions underlying key traits such as growth rate in the indigenous farmed Nile tilapia farmed strains at OWANMWAN Aquaculture Limited hatchery.

Uganda 2024-02-05 13:24:05 2027-02-05 Agricultural Sciences Non-Clinical Trial Non-degree Award
Hope Onohuean
ID:
Appraisal of opioids misuse among a vulnerable population in the western and central region of Uganda
REFNo: HS3486ES

1. To determine the origin of opioid abuse / misuse among vulnerable populations in western/central region of Uganda. 2. To determine epidemiological and psychopathological aspects of opioids abuse/misuse among women in western/central Uganda. 3. To evaluate the contribution of opioid abuse / misuse in western/central region of Uganda. 4. To determine knowledge, attitude and practices (KAP) among pharmaceutical and medical health professionals in western/central region of Uganda. 5. To comment on development of intervention strategies to improve knowledge on responsible use amongst Health care professionals (HCP) / patients.
Nigeria 2024-02-05 13:11:51 2027-02-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Muhumuza Mugisa Edson
ID:
USE OF BLOOD LACTATE THRESHOLD FOR DETERMINING EXERCISE TRAINING VO2 VALUES TO RELIABLY CONTROL HbA1C EXPRESSION IN TYPE-2-PREDIABETICS
REFNo: HS2919ES

The objectives of this study are:
1. To determine whether there will be a significant improvement in the HbA1C expression for the study groups after 3-months of exercise training.
2. To determine whether there will be a significant difference in the HbA1C expressions between the 2mM, 2.5mM, and 4mM experimental groups after 3-months of exercise training.
3. To evaluate the experimental groups and specify which ones will have the observed HbA1C expression improvements.
4. To evaluate the exercise testing-stages within each experimental group for the blood lactate experimental group with the HbA1C dose-response effects threshold during the 3-months of exercise training.

Uganda 2024-02-02 12:19:27 2027-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Chisom  Ezenwa Josephine
ID:
Genetic Determinants of Type-2 Diabetes Mellitus In Individuals of African Ancestry
REFNo: HS3059ES

Identification of genetic variants that are associated with T2D in different African population.
Nigeria 2024-02-02 12:08:57 2027-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Annet Adong
ID:
GAMIFIED SAVINGS AS A PROBLEM GAMBLING INTERVENTION
REFNo: SS1969ES

1. To investigate the impact of prize-linked
savings products on savings among male
youth in Kenya and Uganda.
2. To investigate the impact of gamified
soccer-based prize-linked savings products with a small
reward on gambling expenditure among male youth in Kenya and Uganda.
3. To investigate the impact of gamified soccer-based prize-linked savings products with a large
reward on gambling expenditure among male youth in Kenya and Uganda.


Uganda 2024-02-02 12:07:45 2027-02-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Babirye Ndimwibo
ID:
TREAT INTERACT: Implementing a user involved education- and health system interactive task-shifting approach for child mental health promotion in Uganda
REFNo: HS3144ES

Based on findings from objectives 1-2, develop implementation advice to guide policymakers in school-based child and adolescent mental health (CAMH) management, integration with the health system, and how to implement and sustain large-scale evidence-informed CAMH interventions to contribute towards achieving universal mental health coverage. ,Develop, implement and evaluate an intersectoral supervision, referral and communication model between the health and education sector.,Implement the adapted module-based TREATment mhGAP school program and investigate effective implementation strategies and client outcomes.,Intervention mapping to adapt the mhGAP-IG to a primary school setting, and implementation mapping to develop implementation strategies with user involvement,The main objective of the TREAT INTERACT study is to adapt, implement and evaluate the impact of an adapted school version of the mhGAP-IG that aims to prevent, identify, refer and treat mental health problems in children and adolescents in Uganda through a user involved task-shifting implementation of the mhGAP-IG among primary school staff. This work is divided into 4 work Packages (WPs); each of the specific objectives below represents a single work package.,
Uganda 2024-02-02 12:05:35 2027-02-02 Medical and Health Sciences Clinical Trial Non-degree Award
Kamusiime B.  Samuel
ID:
PUBLIC PENSION SCHEME PROVISIONS AND PERCEIVED FINANCIAL WELLBEING OF RETIRING TEACHERS IN UGANDA: A CASE OF WAKISO DISTRICT GOVERNMENT AIDED PRIMARY SCHOOLS
REFNo: SS2244ES

i) To assess the relationship between the public pension scheme provisions and their implementation process on the financial wellbeing of retiring primary school teachers in Wakiso district.
ii) To examine the effect of the public pension scheme implementation process and the readiness to change jobs on the financial wellbeing of retiring primary school teachers in Wakiso district.
iii) To assess the effect of the readiness to change jobs on the financial wellbeing of retiring primary school teachers in Wakiso district.
iv) To assess the contribution of the public pension scheme provisions on the financial wellbeing of retiring primary school teachers in Wakiso district.

Uganda 2024-02-02 11:53:49 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
Uptake of HPV Vaccination among female adolescents living with HIV/AIDS attending Mityana Hospital ART clinic
REFNo: HS3686ES

 To determine the prevalence and factors associated with HPV vaccination among young female adolescents living with HIV/AIDS at the Mityana Hospital ART clinic
 To assess the facilitators and barriers to HPV vaccine uptake in young female adolescents living with HIV/AIDS at the Mityana Hospital ART clinic using the COM B model.
 To Identify key behaviors that can improve uptake of HPV vaccination among young female adolescents living with HIV/AIDS through workshops using COM Bmodel

Uganda 2024-02-02 11:51:02 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Naris Ninsiima
ID: UNCST-2023-R006134
ENHANCING STAKEHOLDER PARTICIPATION FOR EFFECTIVE MANAGEMENT OF PUBLIC MARKETS IN URBAN AREAS: A CASE OF KABALE AND MBARARA CENTRAL MARKETS
REFNo: SS2314ES

To evaluate the level of stakeholder participation on management decision making in Kabale and Mbarara Central Markets.,To determine the level of stakeholder participation on policy development in Kabale and Mbarara Central Markets,Assess the levels of stakeholder participation on planning in Mbarara and Kabale Central Markets ,To explore significant avenues of stakeholder participation in Kabale and Mbarara Central Markets. ,The general objective to investigate the effect of stakeholder participation in the effective management of Kabale and Mbarara Central Markets. ,
Uganda 2024-02-02 11:38:55 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Tadeo   Nsubuga
ID: UNCST-2023-R007982
Evaluation of the deployment of the call for life (C4L) system among patients diagnosed with Tuberculosis in the Karamoja Sub-region North Eastern Uganda: A mixed-methods study.
REFNo: HS3431ES

1) To compare treatment outcomes among TB patients that utilised call for life (C4L) services and those who did not utilise the services in Karamoja subregion.

2) To understand the barriers and facilitators for utilization of C4L among TB patients that received CallforLife technology services in Karamoja region.
Uganda 2024-02-02 11:34:18 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Komuhangi
ID:
IMPACT OF EDUCATIONAL INTERVENTION ON BREAST SELF EXAMINTAION AS A SCREENING STRATEGY FOR BREAST CANCER AMONG UNIVERSITY FEMALE STUDENTS IN UGANDA
REFNo: HS3762ES

(iv) To evaluate the relationship between knowledge level and social demographic variables.,(iii) To determine post-test knowledge, attitude, and skill of practicing SBE among female university students.,(ii) To equip knowledge and promote the skills of practicing SBE through an education intervention among female university students.,(i) To assess the pre-test knowledge, attitude, and skill of practicing SBE among female university students in Uganda.,The main objective is to assess the impact of educational intervention on Self- Breast Examination (BSE) as a screening strategy for breast cancer to promote health knowledge and practice of BSE among female university students in Uganda.,
Uganda 2024-02-02 11:26:29 2027-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
EVALUATION OF THE USE OF TELEDERMATOLOGY AMONG PRIMARY CARE PATIENTS IN KAMPALA
REFNo: HS3655ES

Aim 3: Define the distribution of dermatologic diagnoses that arise in primary care settings in which TD is used and their subsequent management. ,Aim 2: Evaluate the barriers and facilitators to implementation of the TD service,Aim 1: Describe the utilization of TD in ambulatory care settings. ,
Uganda 2024-02-02 11:24:53 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SIYA AGGREY
ID: UNCST-2019-R001737
VALUES OF BATS TO ECOSYSTEM AND HUMAN COMMUNITIES: IMPLICATIONS FOR THEIR CONSERVATION AND PUBLIC HEALTH AROUND MOUNT ELGON ECOSYSTEM, UGANDA
REFNo: NS718ES

General objective To contribute knowledge relevant in advancing surveillance for One Health-related challenges in Mount Elgon Ecosystem, contributing to improved bat conservation as well as optimal human health. Specific objectives 1. To assess the socioeconomic values of bats in the Mount Elgon ecosystem, Uganda 2. To assess the socioeconomic values of caves in the Mount Elgon ecosystem, Uganda 3. To assess the vulnerability of bat roosts to anthropogenic cave disturbance in the Mount Elgon ecosystem, Uganda 4. To assess the capacities of communities in undertaking disease surveillance tasks for One Health issues
Uganda 2024-02-02 11:21:03 2027-02-02 Natural Sciences Non-Clinical Trial Degree Award
Kawooya  Jimmy
ID:
THE IMPACT OF WELFARE SERVICES ON TEACHER’S PERFORMANCE IN PRIVATE SENIOR SECONDARY SCHOOLS IN WAKISO DISTRICT, UGANDA
REFNo: SS2259ES

(i) To scrutinize the impact of monetary allowances on teachers' performance in private secondary schools in Wakiso District
(ii) To determine the effect of guidance and counselling services on teachers' performance in private secondary schools in Wakiso District
(iii) To investigate the impact of training and development on teachers' performance in private
secondary schools in Wakiso District
(iv) To analyze the influence of housing on teachers' performance in private secondary schools in Wakiso District
(v) To determine the impact of staff flextime on teachers' performance in private secondary schools in Wakiso District
Uganda 2024-02-02 11:19:54 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Michael  Baganizi
ID: UNCST-2023-R006352
Rapid human centred design to develop, test and evaluate a job aid prototype for frontline immunization healthcare workers in Uganda
REFNo: HS3667ES

Needs Assessment 1. To assess the frontline immunization healthcare workers’ perceptions, practices and implementation of procedures using the current job aids. a. How well healthcare workers believe the available job aids support them to perform immunization processes or procedures b. How well supervisors believe the available job aids support their staff to perform immunization processes or procedures 2. To identify processes and procedures that may require a job aid versus another approach to improve HCW performance. Human Centered Design Workshops: 1. To prioritize the problem(s) (as identified through the needs assessment) that need to be addressed with job aid(s) with immunization HCWs and supervisors 2. To design practical, useful job aid prototype(s) around 2YL and catch-up immunizations with immunization HCWs and supervisors. ,1. To assess the uses, preferences and technical requirements of current and future 2YL immunization job aids, with the goal of identifying the knowledge gaps for administering the second dose of measles-containing-vaccine -second dose (MCV2) post introduction, including routine and catch-up vaccine job aids. 2. To design, test, and evaluate a prototype for MCV2 and catch-up immunization job aids with healthcare workers using the HCD methodology.,
Uganda 2024-02-02 11:15:09 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eloise Pedersen
ID:
The effect of payoff and rank on chimpanzee foraging decisions
REFNo: NS724ES

Objective 1: To determine the presence or absence of a preference towards a. high payoff behavioral techniques and b. model rank in chimpanzees. Objective 2: To examine the impact of individual differences on transmission bias preference in chimpanzees.
UK 2024-02-02 11:12:23 2027-02-02 Natural Sciences Non-Clinical Trial Degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
Exploring the mental health needs of orphans and vulnerable children in Nakivale Refugee Settlement, Uganda
REFNo: SS2264ES

• To understand the experiences, needs and views on mental health issues of OVCs and their carers
• To explore factors related to their participation in research

Uganda 2024-01-31 11:19:28 2027-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Tuhairwe
ID: UNCST-2023-R007692
KNOWLEDGE AND ATTITUDE OF UNIVERSITY STUDENTS TOWARDS THE USE OF TELEMEDICINE TO ACCESS SEXUAL AND REPRODUCTIVE HEALTH SERVICES: A CASE OF MBARARA UNIVERSITY OF SCIENCE AND TECHNOLOGY IN UGANDA (KAUSTER STUDY).
REFNo: HS3731ES

Broad objective
To determine the knowledge and attitude of undergraduate students at Mbarara University of Science and Technology (MUST) towards the use of telemedicine to access sexual and reproductive health services.
Specific objectives
i. To assess the knowledge of undergraduate students at MUST of the availability of telemedicine to access sexual and reproductive health services.
ii. To examine the attitudes of undergraduate students at MUST towards the use of telemedicine to access sexual and reproductive health services.
iii). To explore the determinants of knowledge and attitude of undergraduate students of MUST towards the use of telemedicine to access sexual and reproductive health services.
Uganda 2024-01-29 15:22:43 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mia Appelbäck
ID:
Experiences of patients, caretakers and healthcare providers in the referral process for post-partum haemorrhage and other obstetric emergencies to Kawempe National Referral Hospital
REFNo: HS3589ES

Explore the women’s, their partners’ and/or other caretaker’s perception of the implications of the near-miss postpartum haemorrhage event, e.g., health and socioeconomic consequences.,Explore women’s, their partners’ and/or other caretaker’s experience of effective communication, respect and preservation of dignity and emotional support within the maternal healthcare and referral system,Map women’s journey, as well as influencing factors, through the healthcare and referral system from onset of labour to near-miss postpartum haemorrhage , through her, her partner’s and/or other caretaker’s perspective ,To better understand the women’s, their partners’ and/or other caretaker’s perspectives of near-miss postpartum haemorrhage event in the healthcare and referral system,Explore healthcare workers at Kawempe National Referral Hospital perceptions of challenges and facilitating factors when receiving referred obstetric emergencies.,Map the referral process from referring institute to national referral hospital as perceived by healthcare providers,Investigate what challenges and facilitating factors healthcare providers experience in the referral of obstetric emergencies to a higher-level institutions,Explore what factors affect decision-making in the referral of obstetric emergencies to a higher-level facility,To better understand the referral system for obstetric emergencies, primarily PPH, from healthcare providers´ perspectives. ,
Sweden 2024-01-29 15:21:02 2027-01-29 Medical and Health Sciences Non-Clinical Trial Degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
TARGET MALARIA UGANDA PROTOCOL B2- RESEARCH AND DEVELOPMENT: MAINTENANCE OF WILD TYPE An. gambiae COLONIES IN THE ARTHROPOD CONTAINMENT LEVEL 1 (ACL1) INSECTARY AND HANDLING METHODS OPTIMIZATION AND DEVELOPMENT STUDIES Version 1.0 2023
REFNo: NS694ES

1.To Maintain the wild-type Anopheles strains Ag(WT) in the Uganda ACL1 insectary.
2.To support research and development preparatory studies in the insectary.
3.Support to Field Entomology, Stakeholder Engagement Regulatory activities.
4.To develop Staff capacity in preparation for research and development.

Uganda 2024-01-29 15:19:10 2027-01-29 Natural Sciences Non-Clinical Trial Non-degree Award
Japheth Kwiringira Nkiriyehe
ID: UNCST-2019-R000408
What do beneficiaries in the agro sector value chain consider Significant Change from Women Economic Empowerment?
REFNo: SS2141ES

Main Objective
What do beneficiaries of Women Economic Empowerment (WEE) consider significant in their lives?
Specific objective
i) To establish firsthand contextual accounts of what beneficiaries consider WEE to be.
ii) To explore what WEE beneficiaries consider as significant in their life.
iii) To identify ways to improve women economic empowerment interventions

Uganda 2024-01-29 15:15:11 2027-01-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Engineer  Bainomugisha
ID: UNCST-2023-R005928
AirQount: Autonomous vehicle emissions estimation system for low-resource cities
REFNo: SIR277ES

1. Design and build custom hardware for vehicle image capturing system for traffic data collection for training machine learning (ML) models
2. To collect traffic and vehicle data, curate and label the video streams and images resulting in usable datasets for training the AI models
3. Build a machine learning (ML) and computer vision-based system for vehicle recognition and classification that can be linked at available databases on vehicle estimation per vehicle.
4. To build a prototype software system that integrates the hardware and AI models for demonstration of the automated traffic emission estimation system
5. To pilot the developed software and hardware systems and assess their use in vehicle emissions understanding
Uganda 2024-01-29 15:11:28 2027-01-29 Engineering and Technology Non-Clinical Trial Non-degree Award
Namajja Ketty
ID:
Quality assurance and quality control for ethical practice in clinical research conducted in southwestern Uganda
REFNo: SS2263ES

To assess the quality assurance measures employed in clinical research in Southwestern Uganda. To establish quality control procedures used by clinical researchers in Southwestern Uganda. To determine the level of adherence and factors influencing adherence to ethical practices among clinical researchers of Southwestern Uganda
Uganda 2024-01-29 15:09:58 2027-01-29 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
Discrete choice experiment to guide HIV prevention counseling with novel HIV prevention products
REFNo: HS3665ES

To determine preferences for attributes of HIV prevention counseling that would support young women in Uganda to initiate and sustain use of a PrEP product.
Uganda 2024-01-29 14:58:57 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacob Negrey Douglas
ID:
Multisystem aging patterns in chimpanzees (Pan troglodytes schweinfurthii) living at Ngogo, Kibale National Park, Uganda
REFNo: NS727ES

To better understand the biological and ecological forces that shape primate aging, we will assess both longitudinal and cross-sectional, age-related patterns of social, physiological, and physical variation in adult chimpanzees of the notably long-lived groups at Ngogo, Kibale National Park, Uganda. This project will integrate behavioral, genetic, endocrinological, immunological, and microbial data collected from wild chimpanzees. We will combine tried-and-tried observational and laboratory analyses with innovative, noninvasive omics-based approaches to studying physiological function. The proposed research will elucidate the advantages and limitations of wild chimpanzees as models of human health and aging and build an extensive multisystem dataset for future comparative chimpanzee research. The three primary goals of this research are outlined below: 1) Characterize cross-sectional and longitudinal aging trajectories across functional domains. How do functional domains vary in the timing and rate of age-related decline? Do some systems (e.g., physical function, immune function) exhibit later onset and/or slower rates of decline than do others? 2) Determine the extent of sex biases in aging trajectories in Ngogo chimpanzees. Given that female chimpanzees at Ngogo have greater life expectancies at birth than do males [25], do female chimpanzees also show slower or delayed rates of aging across most / all functional domains? Are aging effects more pronounced in some functional domains than others, and if so, which domains show greater sex biases? 3) Develop methods to noninvasively study chimpanzee aging. Given that the study of wild chimpanzees is strictly noninvasive, we will continue to develop, validate, and implement new methods for studying aging across a range of functional domains. Notably, we will continue to refine the use of video recordings to measure walking speeds, which are an invaluable measure of physical function in humans and nonhuman primates alike [32, 33]. We will develop new urinary biomarkers for use in wild chimpanzee studies including biomarkers of neurodegeneration (e.g., Alzheimer’s-associated neuronal thread protein) and physical function (e.g., urinary pentosidine). Finally, we will validate and implement the study of genetic material from chimpanzee saliva samples, including bacterial and epigenetic information, by collecting and subsequently analyzing chimpanzee saliva samples onsite at Ngogo using transportable sequencing equipment (MinION Mk1C sequencer, Oxford Nanopore Technologies, Oxford, UK).
USA 2024-01-29 14:57:37 2027-01-29 Natural Sciences Non-Clinical Trial Non-degree Award
joel lwasa njagala calls
ID: UNCST-2023-R006315
ASSESSING THE IMPACT OF MEDICAL INTERNS ON HEALTHCARE DELIVERY AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: SS2306ES

1.To compare hospital metrics at Kawempe National Referral Hospital when medical interns were present and when they were absent.
2.To compare patient outcomes at Kawempe National Referral Hospital when medical interns were present and when they were absent.
Uganda 2024-01-29 14:56:29 2027-01-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jacqueline Kanywa Balungi
ID:
HPV Vaccine Survey: Determining reasons as to why girls have or have not received the HPV vaccine who attend the clinic at the Baylor Uganda center of excellence.
REFNo: HS3620ES

Primary objective:
To determine reasons as to why 10- to 18-year-old girls receiving health care services at the Baylor Uganda center of excellence have or have not received the HPV vaccine using a short survey during a study period of September 1, 2023 to December 31, 2023.

Long-term goal: To use the responses of this survey to develop educational and clinical counseling programs for increasing the uptake of the HPV vaccine among 9–13-year-old girls at the Baylor Uganda clinical center of excellence.

Uganda 2024-01-29 14:03:23 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hillary Kuteesa
ID:
PROFILES, REFERRAL PATHWAYS AND REASONS FOR REFERRAL FOR PATIENTS ADMITTED TO BUTABIKA NATIONAL REFERRAL MENTAL HOSPITAL.
REFNo: HS3412ES

1. To describe the socio-demographic characteristics of patients admitted to BNRH
2. To describe the referral pathways of patients admitted to BNRH
3. To describe the reasons for referral to BNRH

Uganda 2024-01-25 18:41:36 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Nabirye
ID:
Hand hygiene interventions in Kampala's informal settlements: public health imaginaries local health realities.
REFNo: SS2188ES

1. To trace and characterise the framing of hand hygiene messaging by public health actors in Uganda since 1980.
2. To explore and describe the factors that maintain the preference for hand hygiene messaging among public health actors in Uganda.
3. To understand and compare the lived experiences informal settlement residents with the factors that maintain the preference for hand hygiene messaging by public health actors.

Uganda 2024-01-25 18:40:37 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Juliet Kyayesimira
ID:
Development of Governor’s Plum (Flacourtia indica) Herbal Formulation for the Management of Microbial Infections in Humans
REFNo: NS661ES

4. To determine the appropriate propagation method and conditions for domestication and conservation of F. indica,3. To evaluate the efficacy of formulated prototypes Flacourtia indica extracts for the management of microbial infections,2. To quantify the major phytochemicals of medicinal value in methanolic extracts of F. indica,1. To assess the indigenous uses, genetic diversity and habitat range of Flacourtia Spp. in Uganda,
Uganda 2024-01-25 18:38:49 2027-01-25 Natural Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
Utility of a Liquid Biopsy in the Detection of Metastatic Breast Cancer in Uganda
REFNo: HS3277ES

To determine whether ctDNA can be used as a sensitive and specific measure of tumor burden and response to therapy among women with breast cancer undergoing treatment at UCI,To evaluate the feasibility, sensitivity, and specificity of the liquid biopsy, via ctDNA, to detect and quantify tumor-specific molecular characteristics in patients with metastatic breast cancer at UCI,
Uganda 2024-01-25 18:37:59 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bosco Buruga Apparatus
ID:
Use of information and communication technologies by farmers to enhance the management of agricultural knowledge and information in West Nile Sub-Region of Uganda
REFNo: SS2084ES

Propose an ICT model for enhancing the management of agricultural and knowledge in developing countries using a case of West Nile sub-region, Uganda.,Identify the effects of challenges farmers face in the use of these ICTs for the management of agricultural knowledge.,Determine the challenges faced by farmers in the use of ICT in enhancing the management of agricultural knowledge.,Examine the factors influencing farmers in adopting and using ICTs for enhancing the management of agricultural knowledge in the West Nile sub-region, Uganda.,Find out agricultural stakeholders’ perception of the use of ICT in the management of agricultural knowledge.,Establish the status of managing agricultural knowledge management processes in the West Nile sub-region.,The purpose of the study is to investigate ways in which ICTs can be used to enhance the management of agricultural knowledge in West Nile sub-region of Uganda and to further propose a model to be adopted for enhancing access to agricultural knowledge by stakeholders. ,
Uganda 2024-01-25 18:35:59 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Agnes Kabajuni
ID:
Researching Green Activism: How to better protect minority and indigenous communities, Civil Society Organisations, Networks, and climate Change Defenders in East Africa
REFNo: SS2032ES

Overall Objective: to create an enabling environment for climate change defenders from the ethnic minorities and indigenous peoples to play their role in pushing for responsive climate actions, hold governments accountable and protection of communities adversely affected by climate change impacts in Kenya, Tanzania and Uganda
Specific Objectives: a) Generate knowledge by collecting evidence that leads to a deeper understanding of key stakeholders of the challenges faced by environmental activists from the ethnic and indigenous minorities and traditional knowledge as climate change mitigation strategies.
b) Equip environmental activists from MIPs with knowledge/ideas on how to develop successful strategies to mitigate the challenges they face as part of their work and how to meaningfully blend gender and social inclusion in their work.
c) Promote greater collaboration, cross exchange and learning between duty bearers, civil society movements for inclusive decision-making processes.

Uganda 2024-01-25 18:32:52 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
Field Pilot Study for Histoplasmosis and Aspergillosis testing among patients with Advanced HIV Disease in Uganda.
REFNo: HS2803ES

To determine the integration needs of the Clarus Histoplasma Galactomannan Enzyme Immuno Assay (HGM201) and Sōna Aspergillus Galactomannan Lateral Flow Assay (AGM LFA) in the routine screening, testing and management processes for AHD patients in Uganda. To assess the operational characteristics such as usability and acceptability of the Sōna Aspergillus Galactomannan Lateral Flow Assay (AGM LFA) in the public health context. To assess the operational characteristics such as usability and acceptability of the Clarus Histoplasma Galactomannan Enzyme Immuno Assay (HGM201) in the public health context. To determine the prevalence of invasive aspergillosis in Advanced HIV Disease patients in Uganda. To determine the prevalence of disseminated histoplasmosis in Advanced HIV Disease patients in Uganda.
Uganda 2024-01-25 18:23:34 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
Point of Care (POC) based Interventions to Improve sexual partner testing and tracking for Chlamydia Trachomatis (CT) and Neisseria Gonorrhoea (NG) in Kampala metropolitan STD clinics (POC-PIKAM STUDY)
REFNo: HS1448ES

To estimate the prevalence of commonly occurring causal organisms for genital discharge in men and women (N. gonorrhea and C. trachomatis T. Vaginalis and Gardnerella) infections in men and women attending outpatient clinics in Kampala using molecular diagnostic tests (Xpert) and other point of care tests,To assess the feasibility and reliability of participant self-collection for POC CT/NG tests (Xpert and Binx io CT/NG tests) and evaluate accuracy of the Binx io CT/NG Test against clinician provider and the Laboratory gold standard among persons presenting with genital discharge attending outpatient clinics in Kampala metropolitan .,To describe the perceptions and practices of persons regarding self-collection and self-testing for STD, and STD partner notification among persons with genital discharge attending outpatient STD clinics in Kampala, Uganda.,To evaluate the use of self-collection and self-testing of swabs in increasing the proportion of individuals and partners that get tested and treated for STI among persons presenting with genital discharge attending outpatient clinics in Kampala, Uganda. ,Our overall goal is to evaluate the effect of an intervention that includes; self-collection and partner notification on the proportion of partners of persons with vaginal and urethral discharge who return to the clinic for partner follow up and treatment at outpatient clinics in Kampala district and on management of NG and CT in this population.,
Uganda 2024-01-25 18:21:26 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET NABIRYE
ID: UNCST-2023-R006463
Adoption, Compliance and Effectiveness of MOH-Recommended Biosafety Practices and Guidelines at Public Health Laboratories in Central Uganda: A Cross-Sectional Survey.
REFNo: HS3437ES

1. To evaluate the adoption and compliance of MoH recommended biosafety practices and guidelines at PHLs in Central Uganda

2. To evaluate the effectiveness of MoH recommended biosafety practices and guidelines at Public Health Laboratories (PHLs) in Central Uganda

Uganda 2024-01-25 18:19:01 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
Perceived Maternal Social Support and Perinatal Depression among women in Public health facilities, Mbarara district, south western Uganda (PEMPED)
REFNo: HS3525ES

Aim 1: To determine the prevalence of antepartum depression and its associated factors among pregnant women in latent labor in Mbarara district, south western Uganda

Aim 2: To determine the prevalence of maternity blues at six hours and six days postpartum and its associated factors among mothers in Mbarara district, south western Uganda

Aim 3: To examine the association between perceived maternal social support and postpartum depression among mothers in Mbarara district, south western Uganda

Aim 4: To explore perceived psychosocial support practices, types and preferences by postpartum mothers in Mbarara district, south western Uganda

Uganda 2024-01-25 18:14:54 2027-01-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Fanny Fauli Laessoee
ID:
Agrarian Change – How traditional agricultural knowledge and narratives of the future influence agricultural adaptation to climate change amongst smallholders in Acholiland, Northern Uganda
REFNo: A383ES

3. To explore how narratives of the future influence changing agricultural practices, 2. To examine the role of Traditional Agricultural Knowledge in agrarian change, 1. To identify how small-scale farming practices have changed over time Overall research objective: How are traditional agricultural knowledge and Narratives of the future influencing agricultural adaptation to climate change amongst smallholders in Acholiland, Northern Uganda? ,
Denmark 2024-01-25 18:13:00 2027-01-25 Agricultural Sciences Non-Clinical Trial Degree Award
Kamada Lwere
ID: UNCST-2022-R009359
THE RECRUITMENT AND RETENTION OF ALZHEIMER’S DISEASE DIVERSITY GENETIC COHORTS IN THE ALZHEIMER’S DISEASE SEQUENCING PROJECT(READD-ADSP)
REFNo: HS3097ES

Perform genomic analyses,Management of all phenotype, genomic and biomarker data. ,Process, store, and assay biomaterials for the genomics resource including DNA isolation, plasma, and RNA for future gene expression studies,Adjudication and Harmonization of clinical and neurocognitive data,Develop a large genomics resource for the study of AD in individuals with AF and HL ancestry,The overall goal of this proposal is to build a resource that greatly expands the presentation of currently underrepresented African ancestry (African American (AA) and Africans (AF)) and Hispanic/Latinx (HL) individuals in AD genetic studies.,
Uganda 2024-01-25 18:00:36 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
Feasibility Assessment of a Comprehensive Treatment Approach for Advanced Breast Cancer using Innovative Cancer Medicines in a Low Resource Setting in Uganda.
REFNo: HS3006ES

a. Primary objectives
The primary objectives of the study are to:

I. To measure the number of patients, out of those who are eligible, who are willing to begin immunotherapy within the recruitment period if perceived barriers are removed
II. To determine the proportion of patients who drop out over the duration of the study period

b. Secondary objectives
I. To describe the incidence of adverse events in patients on immunotherapies
II. To elucidate reasons for discontinuation of patients on immunotherapy treatment
III. To determine the factors associated with the acceptability of patients and healthcare workers for immunotherapy
IV. To describe the quality of life of breast cancer patients on immunotherapy

Uganda 2024-01-25 17:55:55 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JAMES  KAYIMA
ID:
The development and testing of a low-cost mHealth intervention to improve blood pressure control in Uganda
REFNo: HS3060ES

1) To assess the level of BP control among ambulatory patients attending the hypertension clinic at Kiruddu National Referral Hospital.
2) To explore the perspectives of patients and providers on the acceptability of a mHealth (mobile app) and enhanced self-care strategy and elicit preferred features of a mHealth strategy for BP control.
3) To develop a mobile app for low-cost phones applying a user-centered design process among patients and providers at Kiruddu National Referral Hospital for control of blood pressure.
4) To assess the feasibility of using the m-health app among patients, community health care workers, and clinicians in Kiruddu National Referral Hospital, focusing on acceptability, practicality, demand, adaptation, and pilot the efficacy of the intervention on BP control.

Uganda 2024-01-25 17:52:25 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edward Mokooza Kibikyo
ID: UNCST-2020-R014923
PREVALENCE AND DETERMINANTS OF SUBSTANCE USE AMONG UNDERGRADUATE STUDENTS AT THE UGANDA CHRISTIAN UNIVERSITY
REFNo: HS3577ES

1. To describe the current model of substance use care and assistance for UCU students.

2. To measure the point prevalence of substance use among undergraduate students at UCU main campus in the January/May semester of 2024.

3. To determine the effect of faith (knowing), religion (doing) and spirituality (Being) on substance use among UCU students

Uganda 2024-01-25 17:43:59 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
A CASE STUDY EXPLORING THE VALUE CHAIN, ENABLERS, OBSTACLES, AND BUSINESS MODELS TO SUSTAIN PRIVATE DIGITAL HEALTH BUSINESS ON GLOBAL GOODS IN UGANDA: A MIXED METHODS CONCURRENT TRIANGULATION STUDY DESIGN
REFNo: SS2051ES

To explore parts of the value chain the companies dealing in digital health are active in and global goods worked with.,To assess barriers(obstacles), enablers for running a private business on digital global goods,To explore business models used to sustain digital health business among the two companies.,i. To explore business models used to sustain digital health business, enablers and barriers to running a private business on digital global goods in Uganda..,
Uganda 2024-01-25 17:40:26 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
ASIIMIRE  DONATH
ID: UNCST-2021-R013270
Male-Led health Promotion Program
REFNo: SS2254ES

To develop questions to inform the development and implementation of the male-led group health promotion program for African refugee men,To collect data from African refugee men, women, and other stakeholders around their understanding of the health education needs, concerns,To develop a Male-Led health Promotion Program” for African Refugee men living in Nakivale Refugee Settlement Camp ,
Uganda 2024-01-25 17:39:17 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
Using Implementation Science To Understand And Design Stakeholder Informed Innovative Interventions To Improve Youth HIV Prevention And Care Continuums In Rural And Urban Uganda
REFNo: HS3625ES

We will use platforms in aims 1 and 2 to strengthen capacity of implementation science and to translate findings into policy and guidelines through clearly defined and established channels. ,To assess the rollout of a culturally acceptable, feasible HIV prevention and care intervention among AYA at high risk, on uptake and persistence to CAB-LA or SEARCH-YOUTH treatment support intervention using implementation effectiveness hybrid designs. Aim 2 will be informed by Aim 1 with regards to specific implementation features. We will recruit AYA (15-24 years) both HIV negative and HIV positive. We will screen them for high risk of seroconversion if negative and for those testing HIV positive unsuppressed or at risk of being unsuppressed. We will assess scale up in real world settings of evidence-based interventions to increase uptake and persistence on CAB-LA (HIV negative) and increase viral suppression (HIV positive) among high risk AYA.,Using the updated CFIR, we will identify determinants (barriers and facilitators) of potential implementation success of two innovations: CAB-LA uptake and persistence and SEARCH-YOUTH (SY) implementation at the community, clinic, organization, provider, and patient levels in five CRPS in urban, semi-urban and rural Uganda. Using CFIR implementation science framework we will conduct in-depth key informant interviews and focus group discussions with five different stakeholder groups:,
Uganda 2024-01-25 17:36:24 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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"A prosperous Science and Technology Led Ugandan Society."