Achilles Katamba
ID: UNCST-2019-R000540
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Clinic versus Hotspot Active Case Finding and Linkage to TB Preventive Therapy (ACF/TPT) Strategy Evaluation for Tuberculosis
REFNo: HS2166ES
3. To estimate (using simulation) the impact of each intervention on diagnostic delays and TB prevalence.,2. To measure the implementation of hotspot-based and facility-based ACF + TPT, including the reach (number of individuals willing to be screened), implementation (measured via cascades of care), and maintenance (of effectiveness over time).,1. To compare the effectiveness of hotspot-focused versus facility-based ACF + linkage to TPT in terms of the number of individuals started on treatment for microbiologically confirmed TB in each community (i.e., reduction in undiagnosed TB prevalence, primary outcome) ,
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Uganda |
2022-05-18 9:43:01 |
2025-05-18 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Penlope Yaguma
ID:
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Electricity access in Uganda's urban slums
REFNo: SS1036ES
Main objective: To investigate the electricity access challenges faced by households and businesses in Nankulabye slum, Kampala, Uganda
Specific Objectives
1. To identify the key socio-economic factors that influence electricity access in the slum
2. To model the daily load profile of a typical household and business in the slum
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Uganda |
2022-05-18 9:32:25 |
2025-05-18 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Ponsiano Ocama
ID: UNCST-2019-R001799
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Prevention of Mother to child transmission of Hepatitis B virus in Uganda: the effect of Birth dose and antiviral therapy on neonatal transmission
REFNo: HS2201ES
Specific objectives
1. To determine prevalence of HBsAg in mothers attending antenatal care in the selected hospitals in Uganda
2. To determine the prevalence of HBsAg among 9-12month-old infants who received the HBV birth dose vaccination and the HBV 3 dose vaccinations and born to HBsAg+ve mothers who had viral load <20,000IU/ ML and never received TDF treatment.
3. To determine the HBsAg prevalence among 9-12month-old infants who received the HBV birth dose and the HBV 3 dose vaccinations and born to HBsAg+ mothers who had a viral load ?20,000 IU/ML and also received 3 months of TDF treatment.
Secondary objectives
a) Assess HBV viral load among pregnant women in different regions of Uganda.
b) Assess the predictor relationship between HBeAg and HBV viral load to transmission of the infection to unborn babies among pregnant women.
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Uganda |
2022-05-18 17:20:32 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Muge Cevik
ID: UNCST-2022-R011548
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Unravelling the role of host microenvironment in the development of phenotypic resistance in Mycobacterium Tuberculosis
REFNo: HS2010ES
1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.
3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes
2. To identify risk factors for poor treatment response among patients with DM and TB 1. To quantify the proportion of mycobacterial LBs in TB-DM patients compared to those with TB alone through a proof-of-concept clinical study.
3.2. Secondary Objectives
1. To assess total proteomic and lipidomic analysis of blood plasma from patients undergoing TB treatment to detect protein and lipid signatures/markers with the potential to predict patients’ clinical outcomes
2. To identify risk factors for poor treatment response among patients with DM and TB
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UK |
2022-05-18 17:18:33 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Stephen Tukwasibwe
ID: UNCST-2022-R011535
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Malaria drug and diagnostic resistance in refugee children in Uganda
REFNo: HS2164ES
1. Compare the prevalence of malaria parasitemia in refugee children arriving at Kyangwali and Adjumani reception centers and nearby non-refugee populations
2. Compare the prevalence of Pf mutations associated with resistance to key antimalarials between refugee and non-refugee populations
3. Compare the prevalence of Pf HRP-2 gene deletions that mediate diagnostic resistance between refugee and non-refugee populations
4. Compare Pf malaria parasites genetic relatedness between parasites isolated from newly arriving refugee children and those in refugees already in camps and in surrounding populations
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Uganda |
2022-05-18 17:05:19 |
2025-05-18 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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FRANCIS KIBIRIGE
ID:
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National Telephone Survey to understand public opinions about governance, public services, social and economic conditions of ordinary Ugandans.
REFNo: SS1244ES
1.To gather Ugandan adults’ attitudes on issues such as economic and living conditions, access to services, and governance.
2.To compare the demographic results from this mixed mode sampling approach with census data, as a means of validating this innovative sampling and data collection approach.
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Uganda |
2022-05-17 9:18:06 |
2025-05-17 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
|
DICKSON NDOBOLI
ID:
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Study of the antimicrobial resistance in bacterial faecal pathogens present in the wildlife-livestock-human interface from geographical areas close to National Parks in Uganda
REFNo: A127ES
1. To assess the risk factors associated with the presence of Campylobacter sp., Salmonella sp. and E. coli, and antimicrobial resistance from geographic areas close to National Parks in Uganda.
2. To determine the antimicrobial resistance pattern of Campylobacter sp., Salmonella sp. and E. coli isolated from faecal samples from wildlife, livestock and human from geographical areas close to National Parks in Uganda.
3. To determine the transmission model of antimicrobial resistance of Campylobacter sp., Salmonella sp. and E. coli based on the wildlife-livestock-human distribution, landscape structure, environmental and human-related factors in geographic areas close to National Parks in Uganda.
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Uganda |
2022-05-17 9:16:53 |
2025-05-17 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
|
Francis Omujal
ID: UNCST-2019-R000428
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INVITRO PROPAGATION, PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF Prunus africana, Warburgia ugandensis, Leonotis nepetifolia AND Aspilia africana OF UGANDA
REFNo: NS130ES
1. To develop an efficient in vitro propagation protocol for P. africana, W. ugandensis, L. nepetifolia, and A. africana.
2. To conduct genetic fidelity assessment and also use Fourier Transform Near-Infrared (FT-NIR) Spectrometer and Soil-Plant Analyses Development (SPAD) to characterize and compare the chemical and chlorophyll content parameters respectively in vitro generated plants.
3. To analyze the phytochemicals in P. africana, W. ugandensis, L. nepetifolia, and A. africana.
4. To evaluate the in vitro and/or in vivo medicinal activities of the different parts of the plants (stem bark, roots, and leaves) on targeted disease conditions i.e. P. africana (prostate cancer and related disease conditions); W. ugandensis (malaria and other conditions including its anti-inflammatory); L. nepetifolia (Malaria), A. africana (Malaria, wound healing).
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Uganda |
2022-05-16 13:11:09 |
2025-05-16 |
Natural Sciences |
|
Non-degree Award |
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Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
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THE UGANDA NON-COMMUNICABLE DISEASE (NCD) RISK FACTORS SURVEY 2022
REFNo: HS2184ES
6. To examine the trends of NCD and associated risk factors in the Ugandan population in relation to the 2014 NCD Risk Factors Survey and in relation to interventions against NCD that were informed by results of the 2014 NCD Risk Factors Survey.,5. To assess preventive measures for selected non-communicable conditions namely cervical cancer screening.,4. To collect data on clinical parameters important in the control and management of NCDs: weight, waist circumference, height, blood pressure, heart rate. ,3. To collect data on socio-demographic characteristics important in the control and management of NCDs: age, gender, level of education, employment, income, marital status,2. To assess the magnitude of biochemical risk factors important in the management of NCDs: raised blood glucose and total cholesterol.,1. To assess the magnitude of the following behavioural risk factors for NCDs:- physical inactivity, tobacco use and harmful use of alcohol and unhealthy diet. ,To determine the magnitude and the associated risk factors of non-communicable diseases (NCDs) among the Ugandan population.,
|
Uganda |
2022-05-16 10:36:32 |
2025-05-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
|
LWABI PETER SOLOMON
ID:
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Quality of Life in Ugandan Children and Young Adults with Repaired Congenital
Heart Disease: Mixed Methods Approach Research objectives
REFNo: HS2115ES
Primary Objective: Assess quality of life in Ugandan children and young adults who have undergone surgery or interventional catheterization for congenital heart disease (CHD).
Secondary Objective(s): Assess clinical and demographic factors that impact quality of life in CHD
population.
|
Uganda |
2022-05-16 10:33:45 |
2025-05-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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