Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Patrick Opondo
ID: UNCST-2022-R010446
 Monitoring and Evaluation analysis of Managing Animal Health and Acaricides for a Better Africa (MAHABA): An assessment of the Impact of MAHABA initiative on Small Scale Producers in Uganda.
REFNo: A387ES

Assess the impact of MAHABA initiative activities on farmers practices, knowledge, perceptions, attitudes and challenges on use of acaricide products for cattle in the control of Ticks and tickborne diseases in selected districts of Uganda with high burden of ticks and tickborne diseases looking across different cattle production systems.,Assess measurable impact on ticks and tick-borne diseases control contributed by outreach activities in the MAHABA initiative,Assess farmer acaricide application practices that may cause sub-optimal tick control and drive acaricide resistance,Assess the economics of ticks and tick borne diseases,Assess the role of youth in ticks and tick borne disease management,Assess the role of gender in ticks and tick-borne diseases management.,Assess opportunities for developing new routes for communication,Assess sources of information on acaricides, ticks and tickborne diseases,Assess protocols selected in controlling ticks and tickborne diseases,Assess acaricide availability to the farmers ,Assess the extent of farmer observed acaricide resistance and treatment failures,Assess farm size and management systems of farmers,Assess the number and proportion of farmers using acaricides ,Assess other production constraints among farmers,Assess the cost controlling of ticks and tick borne diseases among farmers,
 Uganda 2024-02-29 17:26:52 2027-03-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Anne Schel Marijke
ID:
Flexibility in primate vocal behaviour: the role of socio-ecological pressures and context in the production and percep-tion of vocal signals.
REFNo: NS759ES

The general aim of the proposed study is to contribute to the debate about how fluctuations in socio-ecological pressures may lead to more or less flexible behavioural strategies in primate social and vocal behaviour, and what role individual states may additionally contribute to this. This is done by studying the behavioural consequences of (1.) fluctuations in predation pressures and (2.) fluctuations in female reproductive states in two different primate species of the Budongo Forest Reserve: (1.) guereza colobus monkeys (Colobus guereza) and (2.) chimpanzees (Pan troglodytes). For the study on the colobus monkeys, behavioural monitoring, as well as playback experiments, will be conducted to find out whether guereza colobus monkeys flexibly adjust their vocal and social behaviour relative to local differences in predation pressures. For the study on the chimpanzees, only behavioural observation will be conducted, aimed to assess whether female chimpanzees flexibly adjust their vocal and social behaviour relative to reproductive state and food availability. These studies test hypotheses arising from substantial previous work with the Sonso and Kaniyo Pabidi communities of Guereza colobus monkeys and chimpanzees in the Budongo Forest, Uganda, which in the past also entailed observational and acoustical experimental fieldwork.
 Netherlands 2024-02-29 17:25:22 2027-03-01 Natural Sciences Non-Clinical Trial Non-degree Award
David Amwonya
ID: UNCST-2023-R005887
 Inclusive Education in a Post COVID-19 Pandemic: A Case of Pregnant Teenage Learners in Religious run Secondary Schools in Uganda
REFNo: SS2358ES

To establish the level of capacity of the school in supporting the pregnant teenagers to have a conducive and inclusive learning environment,To determine the level of integration and support from teachers and entire school community in enabling the learner to cope with their studies.,To investigate the level of inclusiveness of pregnant teenage learners who enrolled back for their studies after the lockdown.,The main objective of the study is to investigate the level of inclusiveness in the post-COVID-19 period of teenage mothers in secondary schools managed by consecrated perso,
 Uganda 2024-02-29 17:24:43 2027-03-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Shimali
ID:
Influence of Women Empowerment on Children’s Dietary Diversity in Eastern Uganda
REFNo: SS2372ES

The main objective is "To understand how the different dimensions of women empowerment interact with socio-economic characteristics of a woman and that of her spouse and the HH and gender role attitudes to influence dietary diversity for children in Eastern Uganda" It should be revised to read as "To assess how the different dimensions of women empowerment interact with socio-economic position of a woman and that of her spouse and the HH gender role attitude to influence dietary diversity for children in Eastern Uganda"

Specific objectives:

1. To assess the level of women empowerment in Eastern Uganda
2. To determine the relationship between individual characteristics of women, their spouses, and household characteristics on the extent of women empowerment in eastern Uganda 3. To establish the influence of women empowerment on dietary diversity for children in Eastern Uganda
4. To establish the influence of gender role attitude on dietary diversity for children in Eastern Uganda

 Uganda 2024-02-29 17:23:19 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Dennison Kizito
ID:
Evaluation of the BIOPIX-T molecular testing kit’s efficiency on malaria infection in malaria-endemic areas: A case study of Uganda.
REFNo: HS3717ES

Aim:
To test the efficiency and comparison of the malaria BIOPIX-T molecular testing in malaria-endemic areas in Uganda.
Objectives:
1. To compare the BIOPIX-T MALARIA PLASMODIUM PAN-SPECIES KIT with Microscopy and RDTs.
2. To detect the malaria species circulating within the country.
3. To determine the most appropriate duration of testing clinical specimens in remote areas.



Uganda 2024-02-29 17:21:23 2027-03-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maiya Block Ngaybe Grace
ID: UNCST-2023-R007114
 A discrete choice experiment to assess preferences for a future preventative HIV vaccine among at-risk populations in Uganda
REFNo: HS3769ES

General objective This study aims to answer the question of which factors are most preferable among at-risk populations and therefore affect their decisions to take up a preventative HIV vaccine in comparison to other preventative methods through the implementation of a discrete choice experiment (DCE) in Uganda. Specific objectives The objectives of this study will be to conduct key informant interviews which will ultimately inform a DCE which will conducted to determine factors influencing the prospective uptake of a preventative HIV vaccine among People at Substantial Risk for HIV Infection (PSRHI) in Uganda. Objective 1: Identify characteristics of preventative HIV medications which are most preferred regarding the decision to take these medications in Kampala, Uganda by conducting 15-20 key informant interviews. In other words, the purpose of this objective is to identify the characteristics and levels of these characteristics that should be included in the DCE in objective 2. Objective 2: Determine the attributes of a preventative HIV medication that are most valued by PSRHI in Uganda through the implementation of a discrete choice experiment (DCE).
 USA 2024-02-29 17:20:29 2027-03-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Murongo Esau
ID:
Community Participation and Sustainability of Rural Water Supply in Uganda. A Case of Kasese District
REFNo: SS2339ES

To evaluate the mediating effect of community project financing on the relationship between community participation and sustainability of rural water supply in Kasese District,To analyze the contribution of project monitoring and evaluation towards sustainability of rural water supply in Kasese District,To examine the relationship between community project implementation and sustainability of rural water supply in Kasese District,To assess the relationship between community planning and sustainability of rural water supply in Kasese District,To examine the relationship between community participation and sustainability of rural water supply for developing a model to help in planning for the management of rural water sources in Uganda,
 Uganda 2024-02-29 17:16:21 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Vivian Akello Valin
ID: UNCST-2023-R007620
 THE EFFECT OF SOCIOECONOMIC STATUS ON THE OUTCOME OF GASTROINTESTINAL ONCOLOGICAL SURGERIES AND THE ECONOMIC IMPACT OF THESE SURGERIES ON PATIENTS AT MULAGO NATIONAL REFERRAL HOSPITAL.MHREC-2023-102
REFNo: HS3775ES

3. To explore the economic impact of gastrointestinal oncological surgeries on patients at MNRH, including direct medical costs (e.g., surgery, hospitalization, medication) and indirect costs (e.g., lost wages, transportation, caregiving).,2. To investigate the impact of SES on the clinical outcomes of gastrointestinal oncological surgeries at MNRH, such as surgical complications, length of hospital stay, and mortality rate., 1. To identify the socioeconomic status (SES) of patients undergoing gastrointestinal oncological surgeries at MNRH.,1. To measure the effect of the socioeconomic status of patients undergoing gastrointestinal oncological surgeries on the outcome of surgery and the economic impact of these surgeries on the patients at MNRH. ,
 Uganda 2024-02-29 17:14:47 2027-03-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Yotam Gidron
ID: UNCST-2023-R006383
 Redistribution, subjectivity, and the virtual: A view from the south
REFNo: SS2172ES

Evaluate the role of mobile technologies in practices of sharing and redistribution,Map and historicize practices of sharing and redistribution,Explore how new mobile technologies are transforming, or are being incorporated into, indigenous mechanisms and ideologies of sharing and redistribution among Nuer refugees in Uganda. ,
 Romania 2024-02-29 17:10:18 2027-03-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Josephine Namubiru
ID:
The Contribution of Training and Staff Development Policy to Employee Productivity among Middle Level Administrative Staff in Public Universities in Uganda
REFNo: SS2345ES

1. To examine the contribution of training and development policy decisions taken by key players on the productivity of middle-level administrative staff at Makerere University.
2. To establish the relationship between training and human resource development and productivity amongst middle-level administrative staff in Makerere University.
3. To assess the perceptions of middle-level administrative staff on the effectiveness of training and staff development on their productivity.

Uganda 2024-02-29 17:09:23 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Elisa Ndyamuhakyi
ID:
FACTORS ASSOCIATED WITH THE AVAILABILITY OF HUMAN CADAVERS FOR ANATOMICAL STUDIES IN UGANDAN UNIVERSITIES
REFNo: HS3533ES

To determine factors associated with willingness to donate body cadaver among academic staffs in Uganda medical universities.,To assess the willingness to donate body cadavers among academic staffs in medical universities in Uganda.,To ascertain factors associated with availability of cadavers in Ugandan medical schools.,To determine extent of availability of cadavers in Ugandan medical universities.,To determine the profiles cadavers in Ugandan medical universities. ,To ascertain the cadaveric profiles and factors associated with the availability of body cadavers, and willingness to donate body cadavers for anatomical dissection among biomedical science staffs in various Ugandan Universities,
 Uganda 2024-02-29 17:06:57 2027-03-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Melissa Hawkins TR
ID: UNCST-2023-R006088
 A survey of the mammals of the Ajai Wildlife Reserve before, during and after large mammal reintroductions.
REFNo: NS710ES

The small mammals of Uganda have been fairly well studied in some regions of the country, but northern regions lack modern survey data documenting species occurrences. The Ajai Wildlife Reserve is located close to a very important historical ‘type’ location, Rhino Camp, where many original species descriptions were made. Most of these specimens, however, are very old, lack associated molecular tissues, and confound taxonomic advancements in many groups (particularly rodents and shrews). Additionally, per conversations with collaborators and rangers, we have come to learn that large mammal reintroductions are planned for Ajai. Conducting surveys before and after any reintroductions will allow us to evaluate changes through time associated with reintroducing extirpated species to this reserve.
 USA 2024-02-29 17:04:45 2027-03-01 Natural Sciences Non-Clinical Trial Non-degree Award
Martin Origa Jobson Ariel
ID: UNCST-2022-R010809
 Views on cervical cancer and cervical cancer screening among female attendants at the Uganda Cancer Institute.
REFNo: SS2307ES

To explore views of female attendants on cervical cancer and cervical cancer screening.,
 Uganda 2024-02-29 17:03:34 2027-03-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
John Gad Akankwasa Tibesigwa
ID: UNCST-2023-R005985
 A CHRISTIAN APOLOGETIC RESPONSE TO RELIGION REVISIONISM IN UGANDA: A CASE OF THE FAITH OF UNITY RELIGION IN BUNYORO SUB-REGION
REFNo: SS2210ES

3. To examine how Christian apologetics could be used to address the effects religious revisionism by the Faith of Unity religion in Bunyoro sub-region,2. To explore how religion revisionism by Faith of Unity religion is affecting Church ministry in Bunyoro sub-region,1. To Analyse the current predicament of religion revisionism in Uganda,The major objective of this thesis shall be to assess how Christian apologetic could be used as an effective response to the religion revisionism in Uganda using a case of the Faith of Unity religion.,
 Uganda 2024-02-29 17:00:28 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Maria Ndibalekera
ID: UNCST-2022-R008972
 PERCEPTION OF RISK AND PROTECTIVE FACTORS ASSOCIATED WITH CHILD NEGLECT AMONG FATHERS IN WAKISO DISTRICT, UGANDA
REFNo: SS2447ES

To explore the perceptions of fathers about their role in child care in Wakiso District, Uganda.
To investigate the perceptions of fathers about the forms of child neglect perpetrated by fathers in Wakiso District, Uganda
To examine fathers’ perceptions of risk factors for child neglect among fathers in Wakiso District, Uganda.
To examine the perceptions of fathers about the protective factors for child neglect among fathers in Wakiso District, Uganda.

 Uganda 2024-02-29 16:58:18 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Ronald Olum
ID: UNCST-2021-R013821
 Stigma among pregnant adolescents living with HIV/AIDS: Exploring the feasibility of group therapy for its prevention and management in Northern Uganda.
REFNo: HS3089ES

To assess the feasibility of group therapy for the prevention and management of stigma among pregnant adolescents living with HIV/AIDS in Gulu district, Northern Uganda.,To explore the drivers of stigma among pregnant adolescents living with HIV/AIDS in Gulu District, Northern Uganda.,To assess the burden of stigma among pregnant adolescents living with HIV/AIDS in Gulu District, Northern Uganda.,The study aims to assess the burden of stigma, explore the drivers of stigma, and assess the feasibility of group therapy for the prevention and management of stigma among pregnant adolescents living with HIV/AIDS in Gulu District, Northern Uganda.,
 Uganda 2024-02-29 16:48:54 2027-03-01 Medical and Health Sciences Non-Clinical Trial Degree Award
DICKSON NDOBOLI
ID:
Transmission routes and transmission mechanisms of antimicrobial resistant Salmonella enterica, Escherichia coli, Enterococcus faecium and Enterococcus faecalis in the broiler poultry production chain in Uganda
REFNo: A261ES

Main objective

To quantify the occurrence of AMR and elucidate the AMR transmission dynamics along the
poultry value chain in Wakiso and Soroti districts of Uganda

Specific objectives

1. Quantification of E. coli phenotypic resistance using Tetracycline, colistin and
Cefotaxime antibiotics
2. Quantification of antimicrobial resistance profiles of Salmonella and E. coli in Wakiso
and Soroti
3. Determination of factors for persistence of resistant colonies on farms overtime
4. Genetic investigation of mobile genetic elements associated with transfer of AMR
 Uganda 2024-02-29 16:46:42 2027-03-01 Agricultural Sciences Non-Clinical Trial Degree Award
JAMES  SSENFUUMA THOMAS
ID: UNCST-2023-R005484
 RESILIENCE OF REFUGEES EXPERIENCING WFP FOOD AID CUTS IN KYAKA II SETTLEMENT, KYEGEGWA DISTRICT, UGANDA
REFNo: SS2412ES

1. To assess the effects of food reductions by WFP on the social-economic wellbeing of refugees in Kyaka II Settlement, Kyegegwa district


2. To explore the effects of food aid cuts by WFP on social cohesion of refugees in Kyaka II Settlement, Kyegegwa district

3. To explore the survival strategies (protective factors) employed by refugees affected by WFP food aid cuts in Kyaka II settlement, Kyegegwa district, Uganda
 Uganda 2024-02-29 16:43:51 2027-03-01 Social Science and Humanities Non-Clinical Trial Degree Award
Nobert Bongo
ID: UNCST-2023-R008651
 TeamUp Uganda project Research Protocol
REFNo: SS1940ES

3. To assess the role and contribution of public-private partnerships (PPPs) model in improving the quality of life for the youth in Uganda,2. To assess and analyse the extent to which across-sector collaboration efforts by TeamUp Project implementing partner have contributed to improved quality of life for the youth ,1. To establish the impact of three TeamUp interventions; (water, agriculture and Sexual reproductive health) on the youth quality of life,
 Uganda 2024-02-29 16:40:45 2027-03-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hellen Opolot
ID: UNCST-2019-R001724
 The Effect of Public Health Emergencies on the Research Regulatory Systems: A Qualitative Study of COVID-19 In Uganda.
REFNo: SS2192ES

1. To explore the effects of COVID-19 pandemic on NRAs/RECs/researchers’ operations in Uganda.
2. To examine the effectiveness of national policies and guidelines on the conduct of research regulation in Uganda.
3. To describe the coping strategies of researchers, NRAs and RECs amidst the COVID-19 pandemic.

 Uganda 2024-02-28 17:57:26 2027-02-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Martin Origa Jobson Ariel
ID: UNCST-2022-R010809
 The Every Woman Study in Low- and Middle-Income Countries: Identifying challenges and opportunities to improve survival and quality of life for women with ovarian cancer.
REFNo: HS3730ES

To obtain country level reports from the lead clinicians (CL) summarising the environment in which they work to diagnose and treat women, and to interview at least one woman per participating country who might be considered to have a common experience, and who would be willing to be involved in developing advocacy efforts.,To explore the variations in experience of women in their particular country versus the group of respondents as a whole, with a view at looking for opportunities for progress.,To gather sufficient survey responses at a country level to make robust statements about the experiences of ovarian cancer at a national, and larger regional level, and for women in lower- and middle-income countries as a whole.,
 Uganda 2024-02-26 14:03:58 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Immaculate  Mbwali
ID: UNCST-2023-R008116
 Care and support after a miscarriage in Eastern Uganda: a grounded theory exploration
REFNo: HS3543ES

To develop a theory grounded in the data, of care and support for women after experiencing a miscarriage in Uganda. ,To explore the healthcare providers’ and other potential groups’ perceptions and practices of offering care and support to women after a miscarriage in Eastern Uganda.,To explore the experiences of women and their male partners after a miscarriage in Eastern Uganda.,To conduct a metasynthesis to critically reinterpret the existing qualitative literature surrounding experiences of women after a miscarriage.,To understand the social processes surrounding care and support after a miscarriage in Eastern Uganda from the perspectives of women, partners/families, and health workers and to develop a theory of care and support that could inform future research and practice of the care and support for women after experiencing a miscarriage. ,
 Uganda 2024-02-26 13:56:17 2027-02-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Agnes TURYAMUBONA
ID:
Prevalence of protective levels of Anti-Hepatitis B Surface Antigen Antibody titers among Ugandan adolescents living with HIV
REFNo: HS3679ES

To determine the prevalence of acute, chronic and resolved hepatitis B infections from archived Plasma samples of adolescent PLWH at CPHL between January-to- September, 2023. , To determine the prevalence of protective antibody titers against HBV from Plasma samples at CPHL, Uganda obtained from adolescents living with HIV.,To determine the prevalence of Anti-HBs, acute, chronic and resolved HBV infections among adolescents living with HIV at CPHL between Jan to Sept 2023,
 Uganda 2024-02-26 13:53:35 2027-02-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Evaluation of interventions to mitigate effects of adolescent pregnancy and promote maternal and child health in selected districts of Uganda: Uptake, implementation processes, experiences and immediate outcomes
REFNo: HS3874ES

Primary objectives 1. To identify coverage of the interventions to mitigate effects of adolescent pregnancy and promote maternal and child health in the adolescentCOP21 PEPFAR funded districts of Uganda. 2. To determine uptake of interventions by adolescent girls who received pregnancy and motherhood support to mitigate effects of pregnancy and promote maternal and child health adolescentin the COP21 PEPFAR funded districts of Uganda. To measure immediate outcomes within one year of the interventions to mitigate effects of adolescent pregnancy and promote maternal and child healthadolescent in the COP21 PEPFAR funded districts of Uganda. 3. adolescentTo assess implementation processes and dynamics of the interventions to mitigate effects of adolescent pregnancy and promote maternal and child health adolescentin the COP21 PEPFAR funded districts of Uganda . To explore experiences and perceptions of adolescent girls who received pregnancy and motherhood support and implementers towards interventions to mitigate effects of adolescent pregnancy and promote maternal and child health in the COP21 PEPFAR funded districts of Uganda. Secondary objective 1. To identify other existing interventions in place to prevent and respond to adolescent pregnancies adolescent in the COP21 ARPA funded districts. 2. To compare immediate outcomes and effects of adolescent pregnancy between DREAMS and non-DREAMS COP21 ARPA funded districts.
Uganda 2024-02-26 13:52:20 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
LILLIAN MBABAZI
ID:
Storytelling Among the Bakiga of Uganda: Changing Form, Character and Performance Contexts Between 1930 – 2009
REFNo: SS2359ES

To examine the changing form, character, and performance contexts in storytelling among the Bakiga between 1930 and 2009.
To explore the function of storytelling among the Bakiga.
To assess the changing themes, structure, and settings for storytelling among the Bakiga in times of Christianity and formal schooling.
To examine how migration shaped the content, processes and form(s) of storytelling among the Bakiga.
To analyse how commercialisation influenced the composition and performance of storytelling among the Bakiga.
Uganda 2024-02-26 13:49:42 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Winfred  Tugumisirize
ID:
Participatory Budgeting and Financial Sustainability in the Local Government in Uganda: A Case Study of Kabale District
REFNo: SS2353ES

4. To establish the relationship between participatory budgeting and financial sustainability in Kabale District Local Government.,3. To assess the relationship between budget implementation and financial sustainability in Kabale District Local Government.,2. To analyze the impact of budget approval on financial sustainability in Kabale District Local Government.,1. To examine the influence of budget formulation on financial sustainability in Kabale District Local Government . ,The main objective of the study is to examine the relationship between participatory budgeting and financial sustainability of Local Governments in Uganda.,
 Uganda 2024-02-26 13:47:53 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
LILLIAN BYERETA HAPPY
ID: UNCST-2021-R012144
 To utilize simplified instruments for geriatric assessment for specialized routine care of Old People Living with HIV (HIV –OLD, HOPE)
REFNo: HS3704ES

2. To evaluate the feasibility of self-collection (with the support of a research assistant) through tablets of simplified validated tools for Quality of life, Instrumental activities of daily living (IADL), history of falls, screening for depression, and incontinence. 1. To utilize simplified instruments for geriatric assessment of OPLWH which can be potentially scaled up in routine care, particularly for the assessment of frailty, sarcopenia , physical and cognitive function. ,The overall goal of the proposal is to validate simplified tools for specialized routine care of OPLWH. ,
 Uganda 2024-02-26 13:45:25 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kamoga Ronald
ID: UNCST-2019-R001524
 VAGUS NERVE STIMULATION IN A RAT MODEL OF ALZHEIMER’S DISEASE-LIKE SYMPTOMS: MORPHOLOGICAL, IMMUNOHISTOCHEMICAL, MOLECULAR AND BEHAVIORAL CHANGES
REFNo: HS3781ES

1. To conduct a scoping review of literature on vagus nerve stimulation in Alzheimer's-disease and related dementias.
2. To determine behavioral changes associated with vagus nerve stimulation in a rat model of Alzheimer-like symptoms.
3. To evaluate the morphological, Immunohistochemical and molecular changes in the Hippocampus, prefrontal cortex and medial temporal cortex associated with chronic stimulation of the vagus nerve in a rat model of Alzheimer’s-like disease.

 Uganda 2024-02-26 13:43:22 2027-02-26 Medical and Health Sciences Clinical Trial Degree Award
Mallory Holding Anne
ID:
Play Our Part (PoP) project primary data collection on effective engagement strategies with policymakers to support Learning through Play (LtP) in Early Childhood Education (ECE)
REFNo: SS2399ES

To gather data to help answer the PoP CoP learning question 3A: Which Engagement Strategies with Policymakers lead to the creation of enabling environments for LtP in Centre-based systems. ,Identify which advocacy approaches policymakers have found most effective.,Determine the way in which partners are currently engaging in national level advocacy activities and their definition of effectiveness.,Identify effective strategies for engaging policymakers on LtP in ECCE systems. ,
 USA 2024-02-26 13:42:34 2027-02-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sarah Lofgren
ID: UNCST-2019-R001647
 Supervised Treadmill intervention to Reduce Inflammation and Depression through Exercise in HIV: The STRIDE Pilot Study
REFNo: HS3358ES

The objective of this study is to determine the feasibility and acceptability of an aerobic intervention via a treadmill among individuals with HIV and depression in Uganda.
3.1 Primary Endpoint: Feasibility and acceptability of Exercise as a treatment for depression in Ugandans with HIV. This will be measured by:
-Percent completion of the prescribed aerobic exercise intervention, as assessed by research staff logging participation.

3.2 Secondary Endpoint(s)/ Outcome(s):
- acceptability of the intervention assessed via a post intervention survey
-feasibility and acceptability of using a wearable exercise tracker to assess the volume of exercise, based on calories burned and steps achieved, during the intervention period among Ugandans with HIV and depression.
- measure the mean and standard deviation of baseline and 8-week serum BDNF and IL-6 level to estimate an effect size and power a future study.
- measure the mean and standard deviation of baseline and 8-week depression score via PHQ-9 to estimate an effect size and power a future study.
- measure the mean and standard deviation in aerobic fitness baseline and at 8 weeks measured via METS/watts achieved and total time/distance to estimate the effect size for a future intervention.
USA 2024-02-26 13:41:23 2027-02-26 Medical and Health Sciences Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 Intervention Study on Unintended Pregnancy among Teenagers in Busoga
REFNo: SS2284ES

The implementation objective is to evaluate intervention acceptability and scalability in Uganda,The intervention objective is to evaluate a novel model to reach unmarried teenagers and assess its effectiveness in reducing unmet needs for modern contraceptives among the target population,
 Uganda 2024-02-26 13:39:25 2027-02-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Cervical Cancer Screening Utilizing Image Capture and Machine Learning to Identify Precancerous Cervical Lesions
REFNo: HS3743ES

Using pathological confirmation of CIN 2/3+ as the reference standard for pre-cancer, determine if the sensitivity and specificity of image capture of the cervix and artificial intelligence/deep machine learning/interpretation is superior to VIA, the current standard of care for cervical cancer screening in sub-Saharan Africa. ,Evaluate the quality of the cervical images captured in the clinics for use in artificial intelligence/deep machine learning.,Establish an informatics and data management infrastructure for cervical cancer that utilizes the IeDEA data platform and will allow for images and biologic data to be stored and characterized with the AIDS and Cancer Specimen Resource (ACSR) and the National Library of Medicine (NLOM). ,
 Uganda 2024-02-26 13:37:44 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NELSON NSEREKO
ID:
FROM STANDARD SWAHILI TO THE SWAHILI VARIETY SPOKEN IN UGANDA: EVOLUTION AND MORPHOSYNTACTIC VARIATIONS
REFNo: SS2348ES

i) Describe the morphosyntax of the Kiswahili variety spoken in Uganda
ii) Compare and contrast the morphosyntax of Standard Kiswahili with that of the
Kiswahili spoken in Uganda
iii) Account for the emergence of the Kiswahili variety spoken in Uganda

 Uganda 2024-02-26 13:35:31 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Retention through mHealth for adolescents and young adults with HIV in care
REFNo: HS3722ES

Test the acceptability, feasibility, and preliminary impact of the developed adolescent-tailored mHealth intervention for retention in care of AYWH who are new to or newly re-engaging in care,Iteratively develop a social media-based adolescent-tailored mHealth intervention to improve retention in care for AYWH who are new or newly re-engaging in care,Define the cognitive, environmental, and behavioural challenges and their impact on behavioural intention for AYWH who are new or newly re-engaging in HIV care,To develop and test an mHealth intervention for retention in care for adolescents and young adults with HIV,
 Uganda 2024-02-26 13:34:00 2027-02-26 Medical and Health Sciences Clinical Trial Non-degree Award
alfred andama andama
ID: UNCST-2022-R011051
 TONGUE SWAB TUBERCULOSIS DIAGNOSTIC YIELD STUDY
REFNo: HS3761ES

Aim 1. To determine the proportion of people presenting to primary health centers with signs and symptoms of TB who: a. can provide a sample for TB testing (sputum vs. tongue swab) b. have a valid molecular test result (sputum vs. tongue swab) c. are detected as TB-positive (sputum vs. tongue swab) d. prefer providing a sputum vs. tongue swab sample
Uganda 2024-02-26 13:32:44 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 SOLIDARITY TRIAL-A phase I/II Randomized Placebo controlled trial to evaluate the Safety and Immunogenicity of Sudan Ebolavirus in Uganda
REFNo: HS3190ES

Phase I (rVSV-SUDV)
1. To determine the safety of rVSV-SUDV candidate SUDV vaccine among adult healthy volunteers in Uganda.
2. To determine the immunogenicity of rVSV-SUDV candidate SUDV vaccine.

Phase II (ChAdox1, CAd3 and rVSV-SUDV)
Primary objectives
1. To determine the safety of ChAdox1, CAd3 and rVSV-SUDV candidate SUDV vaccines among healthy volunteers and persons with stable comorbidities.
2. To determine the immunogenicity of ChAdox1, CAd3 and rVSV-SUDV candidate SUDV vaccines.
Secondary objectives
1. To determine the durability of SUDV-specific induced immune responses following vaccination.
2. To determine the factors associated with optimal vaccine-induced immune responses.
3. To determine the putative cross reactivity by the SUDV vaccine candidates against other ebolaviruses (e.g. Bundibugyo ebolavirus (BUDV) and EBOV).

Exploratory objectives
1. To determine the effect of SUDV vaccines on host gene expression.
2. To determine the T and B cell specific responses and immune profiling in response to vaccination.
3. To determine the effect of SUDV vaccines on the host metabolome.
4. To determine the effect of SUDV vaccines on host innate immune responses.

 Uganda 2024-02-26 13:31:25 2027-02-26 Medical and Health Sciences Clinical Trial Non-degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
 Building a Culture of Evidence-informed Policy-Making in Uganda (B-CuE)
REFNo: SS2257ES

3) To improve collaboration for better coordinated and complementary support to EIDM in Uganda.,2) To design a sustainable and relevant capacity-building program for pre- and in-service training to ensure individuals and institutions acquire relevant and adequate knowledge and skills to support timely EIDM.,1) To scale-up the activities of the Center for Rapid Evidence Synthesis as a knowledge brokerage institution to strengthen support for timely EIDM in Uganda.,
 Uganda 2024-02-26 13:23:45 2027-02-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
 Exploring the potential of a lower blood pressure threshold for diagnosing hypertension in pregnancy: Implications for pre-eclampsia and stroke.
REFNo: HS3784ES

1. To compare the incidence rate of preeclampsia between pregnant women with SBP from 130 to 139 mmHg and/or DBP from 80 to 89 mmHg and those with normotensive blood pressure below 130/80 mmHg.

2. To compare the incidence rate of stroke between pregnant women with SBP from 130 to 139 mmHg and/or DBP from 80 to 89 mmHg and those with normotensive blood pressure below 130/80 mmHg.

3. To investigate potential risk factors and biomarkers associated with the development of preeclampsia and stroke in pregnant women with elevated blood pressure within the range of 130/80 to 139/89 mmHg.

4. To compare the maternal and foetal outcomes between pregnant women with SBP from 130 to 139 mmHg and/or DBP from 80 to 89 mmHg and those with blood pressures below 130/80 mmHg.


Uganda 2024-02-26 13:20:46 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rawlance  Ndejjo
ID: UNCST-2022-R010993
 Health Systems Resilience in the Face of Climatic Change in Bududa, Kasese and Moroto Districts in Uganda
REFNo: HS3758ES

To explore the barriers and facilitators of building health systems mitigation, adaptation, and resilience mechanisms to deal with the adverse effects of extreme weather events in Bududa, Kasese and Moroto districts in Uganda.,To describe the mitigation and adaptation mechanisms that health systems in Bududa, Kasese and Moroto districts in Uganda employ to deal with the adverse effects of extreme weather events?,To explore how extreme weather events are impacting the disease burden in Bududa, Kasese and Moroto districts in Uganda.,To assess how extreme weather events are impacting disease burden and explore the resilience of health systems in Bududa, Kasese and Moroto districts so as to inform strategies for building resilient and low carbon health systems in the face of climatic changes in sub-Saharan Africa,
 Uganda 2024-02-26 13:19:29 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angelica Kiwummulo
ID: UNCST-2023-R005604
 The impact of digital health technologies on the delivery of maternal and child health services; A case study of Uganda
REFNo: HS3804ES

Evaluate the perceptions of community members, healthcare providers, and other stakeholders regarding the FamilyConnect program to inform opportunities for program optimization and expanded uptake in communities,Assess the success factors and barriers associated with the implementation of Family Connect for insights into program effectiveness.,Assess changes in the prevalence of key infectious diseases within communities using Family Connect app,Assess the changes in attendance rates for antenatal care and other essential Maternal and Child Health (MCH) services before and after the implementation of the Family Connect program,The overall objective of this study is to assess the extent to which Family Connect is influencing behavioral change towards improved uptake of Maternal and Child Health (MCH) services, prevention and control of infectious diseases, and the contextual factors contributing to its success,
 Uganda 2024-02-26 13:17:30 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Munyua Okumu
ID:
Exploring military role expansion and its implications on civil-military relations.
REFNo: SS2335ES

1. Explore what motivates the government of Uganda to “pull” the UPDF into roles that are traditionally non-military.
2. Gain insights on how the involvement of the UPDF in non-military roles is conceptualised and formalised.
3. Explore the experiences of UPDF personnel deployed to non-military roles.
4. Explore the experiences and stories of civilians working with UPDF officers in non-military roles.
5. Establish how best the UPDF should engage with civil authorities in the event of undertaking non-military roles.
 Uganda 2024-02-26 13:14:39 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 CLINICAL PERFORMANCE EVALUATION OF THE COBAS HIV -1/HIV-2 QUALITATIVE ASSAY USING THE COBAS 5800
REFNo: HS3802ES

• To describe and assess the operational characteristics and ease of use of the assay under evaluation and its suitability for use in countries with limited infrastructure (no/limited electricity, no/limited clean water, inadequate means of waste disposal);,To assess analytical performance o Precision; o Limitofdetection; o Subtypedetection; o Cross-contamination or carry-over;, To assess sensitivity and specificity using clinical specimens by comparing with a designated reference standard;,The overall objective of the performance evaluation is to evaluate analytical and diagnostic performance of commercially available qualitative HIV molecular assays undergoing prequalification assessment.,
 Uganda 2024-02-26 13:12:03 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MWEBEMBEZI ATHERIA K
ID:
Management Practices and Financial sustainability of Church of Uganda founded private secondary schools in Greater Ankole Dioceses
REFNo: SS2404ES

To identify the challenges that hinder management practices and financial sustainability and strategies that will enhance financial sustainability in church of Uganda private secondary schools in greater Ankole dioceses. ,To examine the effectiveness of staffing on financial sustainability of Church of Uganda founded private secondary schools in Greater Ankole Dioceses ,To assess the effectiveness of leadership styles on financial sustainability of Church of Uganda founded private secondary schools in Greater Ankole Dioceses ,To analyze the impact of financial management practices on financial sustainability of Church of Uganda founded private secondary schools in Greater Ankole Dioceses,To examine the effect of management practices on financial sustainability of Church of Uganda private secondary schools in Greater Ankole Dioceses. ,
 Uganda 2024-02-26 13:05:57 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Adele Stock
ID: UNCST-2024-R005015
 The Spiritual Life of Water: Aquatic Sacred Space and Urban Environmental Change in 20th century Johannesburg and Kampala
REFNo: SS2389ES

My dissertation research explores how water-based religious practices have been profoundly transformed amidst the immense environmental and legal changes precipitated during the colonial and postcolonial periods in Africa. I examine both the creativity and the resilience of African religious practitioners in making new meaning amidst the displacement of water-based loci of spirituality. In particular, I focus on the paradox of ritual cleansing and healing in polluted bodies of water, a practice that has its roots in the systems of colonization and racial exclusion that are foundational to histories of urban Africa. Kampala’s Lubigi Wetland has long been a vibrant space where diverse groups of Ugandans sought and still seek healing, both physical (particularly at the advent of the HIV/AIDS epidemic) and spiritual. Their resources are a powerful spirit medium thought to connect to spiritual forces in the wetland’s tranquil waters. Yet today, human settlement, environmental degradation, and violent conflict overshadow the swamp’s long history as a spiritual healing center of the Buganda Kingdom.
USA 2024-02-26 13:02:30 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Silver Bahendeka Karaireho
ID: UNCST-2019-R000876
 Effectiveness of Integrating Non-Communicable Disease Services in Primary Care of Rural Districts in Uganda
REFNo: HS3820ES

5. To formulate a potential framework of NCD integration at PHC in Uganda.,4. To determine the burden of NCDs among patients presenting at PHC in the three adjacent districts.,3. To assess the level and determinants of hypertension control achieved by patients with systemic hypertension after intervention.,2. To assess the level and determinants of metabolic control achieved in patients with diabetes after intervention.,1. To ascertain extent and effect of integration of NCDs at PHC achieved by the WDF19-1721 project. The WDF19-1721 project aimed to optimize care of NCDs through integrating delivery of NCDs services at outpatient clinics in PHC.,To evaluate the effectiveness of an NCD health service delivery framework (WDF19-1721 Project) for integrated management of NCDs in Primary Health Care in three adjacent districts of Isingiro, Ntungamo and Sheema located in Western Uganda.,
 Uganda 2024-02-26 13:01:49 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EDGAR GUMA INNOCENT
ID:
Past-year violence exposure and its association with antiretroviral non-adherence among HIV-positive adolescents in Uganda.
REFNo: HS3831ES

To determine the prevalence of violence exposure and its association with antiretroviral non-adherence among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic. , To determine the association between exposure to violence and antiretroviral non-adherence among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic.,2. To estimate the prevalence of antiretroviral non-adherence among HIV positive adolescents who experience Physical, sexual and emotional violence attending the Mildmay Uganda Hospital child and adolescent clinic. ,1. To estimate the prevalence of violence exposure among HIV positive adolescents attending the Mildmay Uganda Hospital child and adolescent clinic. ,
 Uganda 2024-02-23 12:34:51 2027-02-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SHIRAH ZIRABAMUZALE MANSARAY
ID:
Sustainable, Responsible and Inclusive Innovation for Mental Health (SRII4MH): How interactions between the built environment, space and mental health policy influence mental health service delivery in the United Kingdom and Uganda.
REFNo: HS2816ES

To examine how mental health policy, the built environment including architecture, infrastructure and space can be re-engineered to ensure innovative, sustainable and efficient mental health service delivery in the United Kingdom and Uganda.,To examine how the debate on patient-centric/ user-driven innovation has influenced mental health policy and built environment considerations, including architecture and infrastructure considerations in Uganda and UK.,To identify the learning flows regarding the SRII4MH between the global North (UK) and global South (Uganda).,To identify the factors and actors that shape decision making for mental health services in Uganda.,
 UK 2024-02-23 11:46:27 2027-02-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Mutebi
ID: UNCST-2023-R007422
 TUNGIASIS IN EAST-AFRICA – AN INTERDISCIPLINARY APPROACH TO UNDERSTAND THE INTERACTIONS BETWEEN PARASITE AND HOSTS – PROJECT PHASE II PROJECT
REFNo: NS721ES

1.3. To establish the behavioral determinants for the heterogeneous distribution of tungiasis in space and time,1.2.To establish environmental factors which influence the distribution of off host stages in the dry and wet seasons,1. To establish the occurrence patterns of tungiasis among humans in the dry and wet seasons,To improve on the understanding of the ecology of tungiasis, and the developmental biology of Tunga penetrans ,
 Uganda 2024-02-14 12:52:02 2027-02-14 Natural Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 EFFECTIVENESS OF FOOD VOUCHERS & BEHAVIOURAL CHANGE COMMUNICATION INITIATIVES ON THE DIETARY DIVERSITY OF CHILDREN IN AMUDAT DISTRICT, UGANDA
REFNo: HS3748ES

To explore the opportunities and challenges for the sustainability of the intervention in Amudat district.,To establish the determinants of the dietary diversity of children aged 6-23 months in Amudat district.,To assess the association between the intervention and change in dietary diversity of children aged 6-23 months in Amudat district.,To determine the dietary diversity of children aged 6-23 months in Amudat district before and after the intervention.,To evaluate the effectiveness of the food voucher programme combined with a BCC package intervention in improving the dietary diversity of children aged 6-23 months in Amudat district.,
 Uganda 2024-02-13 18:11:51 2027-02-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PAUL TURYAHEEBWA
ID:
“Tax Compliance and Revenue Collection Performance in Selected Commercial Enterprises of Greater Mbarara”
REFNo: SS2287ES

3. To explore the effectiveness of self-assessment system and tax compliance on revenue collection performance in the districts of greater Mbarara,4. To examine challenges that hinder tax compliance and revenue collection performance and advance strategies that will enhance revenue collection performance in commercial enterprises of greater Mbarara,3. To explore the effectiveness of self-assessment system and tax compliance on revenue collection performance in the districts of greater Mbarara.,2. To examine the impact of tax compliance by tax reforms on revenue collection performance among commercial enterprises in the districts of greater Mbarara,1. To analyze the levels of tax compliance on revenue collection performance in commercial enterprises in the districts of greater Mbarara.,The main objective of the study is to examine the effectiveness of tax administration and how it affects revenue collection performance among commercial enterprises in greater Mbarara South Western Uganda,
 Uganda 2024-02-13 18:08:21 2027-02-13 Social Science and Humanities Non-Clinical Trial Degree Award
Iga  David
ID:
ENTREPRENEURIAL SUCCESS AMONG MICRO ENTREPRENEURS IN UGANDA
REFNo: SS2258ES

1. To examine the relationship between
psychological capital and entrepreneurial
success.
2. To contrast the relationship between
emotional intelligence and entrepreneurial
success.
3. To relate the relationship between
individual learning behaviors and entrepreneurial success.
4. To explore the relationship between
entrepreneurial bricolage and entrepreneurial success.
5. To test the combined mediation effect of
entrepreneurial bricolage in the
relationship between psychological
capital, emotional intelligence, individual
learning behaviors and entrepreneurial
success.

 Uganda 2024-02-13 18:05:55 2027-02-13 Social Science and Humanities Non-Clinical Trial Degree Award
Derrick Semugenze
ID: UNCST-2023-R007934
 Association of human cytomegalovirus (HCMV) and other viral exposure with susceptibility and progression to tuberculosis disease
REFNo: HS3255ES

Association of HCMV and other viral infections with tuberculosis progression among household and close contacts to tb index cases,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive children from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from Uganda,Association of human cytomegalovirus (HCMV) exposure with tuberculosis susceptibility in TB presumptive adults from South Africa,Association HCMV and other viral infections with susceptibility and progression to tuberculosis disease,
 Uganda 2024-02-13 18:03:22 2027-02-13 Medical and Health Sciences Non-Clinical Trial Degree Award
Tobby Agwe Michael
ID:
Production and Cleansing of Biogas from Bio-degradable Municipal Solid Waste – A Way of Resource Recovery
REFNo: SIR276ES

• To Design and fabricate the system components of the biogas production plant.
• To prepare the organic fraction of the Municipal Solid Wastes.
• To anaerobically digest the Shredded Biodegradable Municipal Solid wastes.
• To cleanse the biogas.

 Uganda 2024-02-13 17:57:42 2027-02-13 Engineering and Technology Non-Clinical Trial Non-degree Award
Alain Favina
ID:
Preparedness of private health workers in Mbarara City about identifying and managing Ebola outbreaks
REFNo: HS3424ES

To determine the relationship between the wellbeing of private health workers and their preparedness towards the Ebola outbreak in Mbarara city,To determine the knowledge, attitude, and practice towards the Ebola outbreak by health workers in private clinics in Mbarara city.,To determine the level of preparedness for the Ebola outbreak by health workers in private clinics in Mbarara City,
 Burundi 2024-02-13 17:56:53 2027-02-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
 Sabin 003: A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults
REFNo: HS3628ES

To evaluate the safety and tolerability of cAd3-EBO S vaccine
 Uganda 2024-02-13 17:35:43 2027-02-13 Medical and Health Sciences Clinical Trial Non-degree Award
Friday Christopher
ID: UNCST-2023-R007260
 SUSTAINABLE LAND MANAGEMENT PRACTICES AND ENVIRONMENTAL PROTECTION IN KABALE DISTRICT, UGANDA
REFNo: SS2370ES

i. To examine the effect of agroforestry on environmental protection in Kabale district, Uganda. ii. To determine the influence of crop rotation on environmental protection in Kabale district, Uganda. iii. To assess the effect of trenches and check dams on environmental protection in Kabale district, Uganda. iv. To establish the influence of mulching on environmental protection in Kabale district, Uganda. v. To evaluate the effectiveness of government policies in promoting environmental protection in Kabale district, Uganda.
Uganda 2024-02-09 23:38:35 2027-02-09 Social Science and Humanities Non-Clinical Trial Degree Award
Josephine Nayiga
ID: UNCST-2023-R005839
 Addressing bioethical challenges in HIV research to inform the development of a training program at Makerere University
REFNo: HS3771ES

3. Identify the preferences of trainees regarding future training in bioethics and ascertain their perceived knowledge gaps related to research bioethics,2. Investigate the perspectives of senior investigators at IDI and faculty members at Makerere University based on their experiences, focusing on the ethical dilemmas encountered by trainees engaged in HIV research,1. Evaluate the existing level of awareness and knowledge concerning bioethical challenges in HIV research among current and former trainees at IDI and the School of Medicine, Makerere University,To understand the training needs in research bioethics for trainees in the area of HIV and co-infections, in order to inform the development of a training program at Makerere University,
 Uganda 2024-02-09 23:36:15 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David  Ejalu Livingstone
ID:
ART Adherence among HIV-positive virally unsuppressed adolescents and young people: feasibility, acceptability, and effectiveness of a community-based implementation strategy to optimise compliance with intensive adherence counselling in East-Central Uganda.
REFNo: HS3807ES

1. To determine the level of compliance to IAC and the associated factors among virally unsuppressed Adolescents and Young People living with HIV in East Central Uganda.
2. To explore individual and system-level barriers to and facilitators of compliance to intensive adherence counselling protocol for enhancing ART adherence among unsuppressed Adolescents and Young People living with HIV in East-central Uganda.
3. To design a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence for enhancing VLS among unsuppressed AYP in East-central Uganda.
4. To Evaluate the feasibility, acceptability, and effectiveness of a multifaceted theory-informed community-based IAC Implementation Strategy to optimize adherence among unsuppressed AYP in East-central Uganda.

 Uganda 2024-02-09 23:35:00 2027-02-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Elyanu James
ID: UNCST-2021-R013210
 Closing TB Gaps using patient-centered approaches to improve TB Screening, Diagnosis and Prevention among people living with HIV
REFNo: HS3664ES

To assess the performance of novel TB screening algorithms among children,
adolescents, and adults living with HIV and presenting for routine care across a network
of family centered HIV clinics in Uganda and other four sub-Saharan African countries as
compared to the current WHO recommended symptom-based screening strategy.
To compare new diagnostic strategies leveraging the evaluation of multiple specimens
(stool and oral swab Xpert Ultra, early morning urine LF-LAM, point-of-care ultrasound
(POCUS), and a design locked Xpert Host Response Test against a reference standard
(Xpert Ultra on spot and early morning respiratory specimens) to improve diagnostic yield.
To compare the proportion of PLHIV who initiate and complete TPT with 3HP or 6H within
the context of a patient centered differentiated service delivery model allowing selection
of TPT regimen and randomly allocating enhanced adherence support versus the
standard of care for TPT and adherence support.
To evaluate the cost-effectiveness of screening and diagnostic strategies as well as
comparative TPT regimens for the prevention of TB disease among children, adolescents
and adults living with HIV
 Uganda 2024-02-09 23:32:58 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Birungi
ID: UNCST-2023-R005605
 A Family centred approach to enhance lifestyle change and behavioural modification for prevention of cardiovascular diseases among adolescents and their families in Uganda (FaCe-D) study
REFNo: HS3682ES

Main Objective
1. 1. We aim to explore the knowledge on cardiovascular health including CVD risk, perceptions and attitudes of participants, providers and other stakeholders towards the ihealth-T2D family-centered approach (FCA) as an intervention, obtain their input in the modification and design of the intervention to make it appropriate for Ugandan context
Specific Objectives
1. To explore the knowledge on cardiovascular health, perceptions, preferences and recommendations from potential participants on the proposed family-centered approach as an intervention for reducing and controlling common CVD risk factors among adolescents and their families.
2. To identify potential facilitators and barriers to adapting and implementing the FCA intervention in Uganda.
3. To use the data generated to design implementation strategies to promote the delivery, and uptake of the adapted FCA
 Uganda 2024-02-09 23:29:31 2027-02-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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