Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Ponsiano Ocama
ID: UNCST-2019-R000440
 Clinical responses and novel biomarkers of antiviral treatment for prevention of HBV- and HBV/HIV-associated hepatocellular carcinoma
REFNo: HS1782ES

1. To define the response to HBV antiviral treatment in terms of standard and novel viral biomarkers and stabilization or regression of liver fibrosis among HBV mono-infected and HBV/HIV coinfected persons.
2. To identify clinical and viral factors associated with break-through HCC despite guideline appropriate HBV treatment and HCC surveillance, and evaluate if HCC stage at presentation or survival is moderated.
3. To assess the human serum albumin (HSA) adductome biomarker profile and dosimetry associated with HBV treatment need and with ‘functional cure’ in response to HBV antiviral treatment among HBV mono-infected and HBV/HIV coinfected persons.

Uganda 2022-05-31 10:36:39 2025-05-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Koogler
ID:
Social Relationships and Child Labor Migration from Karamoja, Uganda: An Exploratory Study
REFNo: SS1302ES

•Investigate the social risk factors related to child labor migration •Explore the nuances of the social lives of child labor migrants, including both strengths and negative aspects of social relationships •Propose policies and potential interventions that reflect the true structure and dynamics of social networks for preventing child labor migration, mitigating the most dangerous forms, and withdrawing migrant children from labor
 USA 2022-05-30 17:20:41 2025-05-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
ALICE GITAU WANGARI
ID:
FACTORS ASSOCIATED WITH CUMULATIVE INCIDENCE OF GESTATIONAL RHINITIS, AND ITS EFFECTS ON QUALITY OF LIFE AMONG MOTHERS ATTENDING MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2239ES

1.To determine the cumulative incidence of gestational rhinitis in Mbarara Regional Referral Hospital
2.To determine the factors associated with gestational rhinitis among mothers attending Mbarara Regional Referral Hospital
3.To assess the quality of life among mothers with symptoms of gestational rhinitis attending Mbarara Regional Referral Hospital

 Kenya 2022-05-30 17:17:54 2025-05-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Ahamya William
ID:
A Framework to Enhance Confidentiality and Privacy of Data in Motion.
REFNo: SIR102ES

Carryout a preliminary study to measure the effectiveness and efficiency of the designed framework.,To design a framework aimed at enhancing confidentiality and privacy of data in motion,To find out the weaknesses in the existing frameworks and establish requirements to improve the confidentiality and privacy of data in motion.,The main objective of this study will be to improve the existing frameworks by designing one with enhanced confidentiality and privacy of data in motion in car sensors.,
 Uganda 2022-05-30 17:16:31 2025-05-30 Engineering and Technology Non-Clinical Trial Degree Award
George Mpanga Lutwama
ID:
Ugandan Veterans and the First World War
REFNo: SS1209ES

To identify the names of Ugandans who fought and died during the First World War.
 Uganda 2022-05-30 17:14:58 2025-05-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kizito Muwonge
ID: UNCST-2022-R011250
 Methicillin Resistant Staphylococcus aureus Carriage among selected livestock species in designated Districts in Uganda
REFNo: A187ES

1. Determine the burden of MRSA in cattle, goats, sheep and swine in the study districts
2. Determine the burden of MRSA in high - risk human categories in the study districts
3. Determine the knowledge, attitudes and practices of antimicrobial users towards antimicrobial resistance in the study districts
 Uganda 2022-05-30 17:14:03 2025-05-30 Agricultural Sciences Non-Clinical Trial Degree Award
Joshua Muhumuza
ID:
Effect of chewing gum on duration of postoperative ileus following laparotomy for gastroduodenal perforations; a multi centre study.
REFNo: HS1665ES

i. To compare the time taken for post-operative ileus to resolve in the two groups. ii. To compare the duration of hospital stay in the two groups. iii. To determine other factors associated with the duration of post-operative ileus in the study population.
 Uganda 2022-05-30 17:10:09 2025-05-30 Medical and Health Sciences Clinical Trial Degree Award
JUSTUS KIRABIRA
ID:
ASSOCIATION BETWEEN HIV SEROSTATUS AND PREMALIGNANT CERVICAL LESIONS AMONG WOMEN ATTENDING CERVICAL CANCER SCREENING CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2258ES

1. To determine the prevalence of HIV among women attending cervical cancer screening Clinic at MRRH
2. To determine the prevalence of premalignant cervical lesions among HIV positive and HIV negative women attending cervical cancer screening Clinic at MRRH
3. To establish the association between HIV and premalignant cervical lesions among women attending cervical cancer screening Clinic at MRRH.

 Uganda 2022-05-27 19:02:21 2025-05-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Rukiya salim Abdillahi
ID:
Prevalence, clinical manifestations of pregnancy dermatoses and their effect on quality of life among women attending MRRH
REFNo: HS2238ES

To establish the prevalence of pregnancy dermatoses among women attending ANC clinic at MRRH.

To describe the clinical manifestations of pregnancy dermatoses among women attending ANC clinic at MRRH.
To assess the effect of pregnancy dermatoses on the quality of life of women attending ANC clinic at MRRH.

 Kenya 2022-05-27 18:57:18 2025-05-27 Medical and Health Sciences Non-Clinical Trial Degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
 African Surgical Outcomes Study in Paediatric patients (ASOS-Paeds)
REFNo: HS2179ES

In paediatric surgical patients < 18 years in Africa: To determine the association between pre-operative, intra-operative and facility factors with postoperative complications and death. ,In paediatric surgical patients < 18 years in Africa: To determine the incidence of intraoperative severe critical incidents,,In paediatric surgical patients < 18 years in Africa: To determine the in-hospital postoperative mortality rate up to 30 days post-surgery,,To determine the incidence of in-hospital postoperative complications up to 30 days post-surgery in paediatric surgical patients <18 years in Africa,
 UK 2022-05-27 18:55:24 2025-05-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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