Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Achilles Katamba
ID: UNCST-2019-R000540
Evaluating the accuracy of spatial interpolation methods for estimating residential ambient PM2.5 exposure concentrations in Kampala, Uganda.
REFNo: HS2396ES

General objective 1. To determine the accuracy of estimating residential ambient PM2.5 exposure concentrations in urban Uganda when using various spatial interpolation methods, and to test if certain factors collected from a household survey and neighborhood checklist are correlated with ground level PM2.5 concentrations. Specific objectives 1. To estimate concentrations of outdoor PM2.5 for parishes in Kampala, Uganda using low-cost air sensors and multiple spatial interpolation models. 2. To measure ground-level outdoor PM2.5 concentrations in selected urban residences in Kampala, Uganda and compare these measurements to modelled estimates. 3. To measure indoor PM2.5 concentrations in selected Kampala households and compare against outdoor PM2.5 concentrations using measurements collected at the same residence. 4. To determine household activities that are significantly related to indoor and outdoor PM2.5 concentrations. 5. To determine neighbourhood characteristics that are significantly related to indoor and outdoor PM2.5 concentrations
Uganda 2022-08-11 18:23:42 2025-08-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Jane Achan Edwin
ID: UNCST-2023-R005498
Determining the prevalence of malaria and long-term complications following SARS-CoV-2 infection and assessing health care pathways for the management of fever and other long-term complications following SARS-CoV-2 infection
REFNo: HS2354ES

Primary Objectives:
1. To compare the prevalence of and risk factors for malaria infection among individuals with and those without previous SARS-CoV-2 infection in Ethiopia and Uganda 2. To describe the association between previous malaria exposure and risk of SARSCoV-2 infection

Secondary Objectives:
1. To compare the clinical presentation of malaria infection among individuals with and those without previous SARS-CoV-2 infection in Ethiopia and Uganda
2. To describe malaria parasite kinetics among individuals with and those without previous SARS-CoV-2 infection in Uganda only
3. To compare the prevalence of fever among individuals with and those without previous SARS-CoV-2 infection in Ethiopia and Uganda
4. To determine the prevalence of long-term complications of COVID-19 and describe the clinical spectrum of long-term complications of COVID-19 among individuals with previous SARS-CoV-2 infection in Ethiopia and Uganda
5. To describe the predictors of and risk factors for long-term complications of COVID-
19 among individuals with previous SARS-CoV-2 infection in Ethiopia and Uganda
6. To describe the association between previous malaria exposure and the development of long-term complications of COVID-19 among individuals with previous SARS-CoV-2 infection in Ethiopia and Uganda

Tertiary Objectives:
1. To describe health care pathways for the management of fever and malaria among individuals with and those without previous SARS-CoV-2 infection in Ethiopia and
Uganda
2. To describe health care pathways for the management of long-term complications of COVID-19 among individuals with previous SARS-CoV-2 infection in Ethiopia and
Uganda


Uganda 2022-08-11 18:22:28 2025-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SSEDYABANE FRANK
ID: UNCST-2022-R011175
MULTIMORBIDITY OF METABOLIC SYNDROME AND CERVICAL INTRAEPITHELIAL NEOPLASIA: CORRELATION BETWEEN SELECTED BLOOD BASED BIOMARKERS OF METABOLIC SYNDROME WITH CERVICAL INTRAEPITHELIAL LESIONS
REFNo: HS2395ES

• To establish the relationship between serum levels of insulin resistance markers (IGF II and IGF-BP3) with treatment outcomes of cervical intraepithelial neoplasia among women seeking cervical cancer care at Mbarara regional referral hospital (MRRH).,• To establish the relationship between serum levels of Insulin like Growth Factor II (IGF II) and Insulin like Growth Factor II binding protein 3 (IGF-BP3) with grades of cervical intraepithelial neoplasia among women seeking cervical cancer care at Mbarara regional referral hospital (MRRH). ,• To determine the prevalence and risk factors of obesity; and establish its relationship with grades of cervical intraepithelial neoplasia among women seeking cervical cancer care at Mbarara regional referral hospital (MRRH). Obesity will be defined as a body mass index of over 30kg/m2.,• To determine the prevalence and risk factors of dyslipidaemia; and its correlation with grades of cervical intraepithelial neoplasia among women seeking cervical cancer care at Mbarara regional referral hospital (MRRH). Dyslipidaemia will be defined as increased total serum cholesterol, triglycerides, low density lipoprotein and a reduced serum high density lipoprotein.,To determine the prevalence of selected metabolic syndrome components (dyslipidaemia, obesity and insulin resistance); establish their risk factors and relationship with grades, as well as treatment outcomes of cervical intraepithelial lesions among women seeking cervical cancer care at Mbarara Regional Referral Hospital (MRRH). ,
Uganda 2022-08-11 18:21:25 2025-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Kisaame Keith
ID:
Conducting a Qualitative Comparative Regional Study on Online Violence Against Women in Kenya, Rwanda, Tanzania and Uganda
REFNo: SS1332ES

•To document 12 OVAW cases reported in the traditional media in Kenya, Rwanda, Tanzania and Uganda. •To examine the balance in traditional media coverage of the 12 OVAW cases in Kenya, Rwanda, Tanzania and Uganda. •To undertake a comparative analysis of how balanced traditional media coverage of OVAW is across Kenya, Rwanda, Tanzania and Uganda. •To document perspectives of key actors on OVAW in Kenya, Rwanda, Tanzania and Uganda
Uganda 2022-08-11 18:19:59 2025-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rena Deitz
ID:
Do good intentions translate? The rise, transfer, and localization of Social Emotional Learning (SEL)
REFNo: SS1325ES

To develop a locally relevant measure / instrument of SEL that can be used by education practitioners in Uganda,To provide youth (refugee and host community) the skills and experience in co-designing a research instrument,To assess the differences between locally and globally defined SEL,To understand the transfer of "social emotional learning" (SEL) through foreign aid and the differences between local and global values around SEL,
USA 2022-08-11 15:40:14 2025-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Femke Bannink Mbazzi Bannink
ID: UNCST-2023-R008308
The Missing Billion: Using participatory approaches to improve access to healthcare for disabled people in Uganda.
REFNo: SS1348ES

The objective of this study is to generate evidence to inform the content and implementation of community-based participatory learning and action (PLA) groups for people with disabilities in Uganda.
Netherlands 2022-08-10 18:10:15 2025-08-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
GLADYS NAKIDDE
ID:
Prevalence, Correlates, Quality of Care for Maternal Mental Health Problems in Formal and Informal Healthcare Settings in South-Western Uganda: The Case of Mbarara and Kabale Districts
REFNo: SS1362ES

To explore complementary and alternative therapies used to manage MMH problems,To assess the extent to which MMH care interventions in maternity care settings meet the needs of patients and their families,To determine the correlates of common Maternal mental health problems ,To determine the prevalence of common Maternal mental health problems,To assess the prevalence, correlates and quality of care for common MMH problems in formal and informal healthcare settings in South Western Uganda,
Uganda 2022-08-10 18:06:48 2025-08-10 Social Science and Humanities Non-Clinical Trial Degree Award
Jean de Dieu IRAGENA
ID: UNCST-2021-R012248
Roll-out and Scale-up of WHO-endorsed technologies for TB diagnosis in Africa: opportunities, strengths and challenges.
REFNo: HS2393ES

Specific objective 3: To develop an “easy to implement tool” including good practice and lessons learnt from the use of TB laboratory services and diagnostics to support recent pandemic and emergency disease aoutbreaks in Africa as a guide to assist member states in better use of opportunities from TB services for integrated diagnosis of other diseases.,Specific objective 2: To document predisposing, enabling and need factors influencing rapid uptake of WHO-endorsed TB diagnostic technologies,Specific objective 1: To assess the status of uptake of all WHO-endorsed TB diagnostic technologies between 2007 and 2017 in a systematic review and meta-analysis. However, collected and analyzed data will go beyond 2017 (up to 2021 to include the most recent tests even in 2021). Some countries may have not implemented a test by 2017 but thereafter they got resources and adopted those recommendations on TB diagnostics. I will focus on both, public and private sectors together.,Main objective: To demonstrate the implementation status, highlighting strength, challenges and opportunities, of WHO-endorsed technologies to diagnose TB, HIV-associated TB and Multi/Extensively Drug –Resistant TB in Sub-Saharan Africa.,
Rwanda 2022-08-09 9:28:21 2025-08-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Tobias Klaus
ID:
Africa: Research and Teaching platform for Development - Sustainable Modular Grids for Grid Stability (ART-D Grids)
REFNo: SIR94ES

Together with the African and German partners, the objective of the project is to develop new ways of electrifying remote regions in East Africa through microgrids and their interconnection. These grids on the one hand meet the needs of rural communities for a robust and largely uninterruptible energy supply and on the other hand meet the politically motivated need for a centrally well-manageable power supply within the framework of a national grid. Many years of experience have shown that an interdisciplinary approach makes sense for such a project, since the sustainable operation of infrastructure systems not only depends on sound technology, but social and economic factors also influence sustainable operation.
Germany 2022-08-09 9:22:32 2025-08-09 Engineering and Technology Non-Clinical Trial Non-degree Award
JULIET NABBAALE
ID: UNCST-2021-R012237
CLINICAL, LABORATORY AND ECHOCARDIOGRAPHIC OUTCOMES AMONGST UGANDAN WOMEN WITH PERIPARTUM CARDIOMYOPATHY
REFNo: HS2268ES

Sub study 1: To determine the impact of Right Ventricular Function on Left Ventricular dimension and contractility, measured by echocardiography among women with PPCM.
Sub study II: To determine the impact of biomarkers on cardiac remodeling amongst PPCM women.
Sub study III: To determine adherence levels to Enalapril among women with PPCM.
Sub study 1V: To determine the correlation between proteomics and Right Ventricular Fibrosis amongst women with PPCM.

Uganda 2022-08-08 9:56:45 2025-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
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