Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Nakyaze
ID:
Provider Perspectives on the PrEP Ring (“ProPrEP”): views from a maternal and child health program (“BAMA”) serving young mothers in rural Uganda.
REFNo: HS4468ES

General Objective
The study will deepen our understanding of provider perspectives on use of the PrEP vaginal ring among young mothers living in rural areas of Uganda.
Specific Objectives
1. Identify preliminary areas for education and outreach to improve both provider and end-user understanding/knowledge of the new vaginal ring technology, thus increasing likelihood of quality counseling and uptake among a vulnerable population of young mothers.
2. Explore the reception by health care personnel of promotional and information/education/counseling (IEC) materials developed by the multilateral “Catalyst” study (funded by PEPFAR through USAID) for ring launch, especially in rural regions having distinct health services resources; identify areas for possible adaptation or elaboration for best uptake and use by health workers
3. Expand understanding of facilitators and barriers faced by young mothers in accessing HIV prevention information and services, especially:
a. community and peer-based stigma
b. provider attitudes
c. models of service provision linking maternal health and HIV prevention/care

Uganda 2024-08-26 18:29:44 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
 Epidemiological Profile of Malaria and Molecular Characterization to Assess Presence and Potential Contribution of Emerging Parasite Populations to Malaria Epidemics in Epidemic Districts in Eastern Uganda
REFNo: HS4786ES

General objective
To describe the epidemiological profile of malaria and assess presence and potential contribution of new emerging parasite populations to persistent epidemics in malaria
epidemic districts in Eastern Uganda
Specific objectives
1. To describe the trend and epidemiological profile of malaria in five epidemic districts in Eastern
Uganda over the past 5-year period
2 . To assess presence and potential contribution of emerging parasite species to epidemics by
molecular characterization of malaria parasite populations in epidemic districts in Eastern Uganda
3 . To assess presence and potential contribution of emerging parasite populations harboring
molecular markers of artemisinin resistance to persistent epidemics in malaria epidemic districts
in Eastern Uganda
4 . To assess presence and potential contribution of emerging parasite populations harboring pfhrp2
and pfhrp3 gene deletions to the persistent epidemics in malaria epidemic districts in Eastern Uganda
 Uganda 2024-08-26 18:28:33 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
MUGISHA TAREMWA IVAN
ID: UNCST-2024-R004274
 Assessment of Transfusion Safety and Efficacy among Cancer Patients in Uganda and Caregivers’ Perceptions on Blood Use.
REFNo: HS4848ES

Specific objectives: (i). To assess the level of bacterial contamination in stored whole blood and blood components intended for transfusion to patients with cancer at Mbarara Regional Referral Hospital and Uganda Cancer Institute. (ii). To determine the prevalence of, and the factors associated with immune sensitization among patients with hematological malignancies at Mbarara Regional Referral Hospital and Uganda Cancer Institute. (iii). To identify the specificities of anti-RBC alloantibodies in patients with hematological malignancies at Mbarara Regional Referral Hospital and Uganda Cancer Institute (iv). To determine the incidence of acute and delayed serologic or delayed hemolytic transfusion reactions among patients with cancer at Mbarara Regional Referral Hospital and Uganda Cancer Institute (v). To describe the caregivers' perceptions of blood use and availability in southwestern Uganda. Main objective: To assess transfusion safety and efficacy among patients with cancer in Uganda and caregivers’ perceptions of blood use.
 Uganda 2024-08-26 18:26:57 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Edward  Tumwesige
ID: UNCST-2024-R003855
 Assessing Community Willingness and Acceptance to Utilize Locally Developed Vaccines
REFNo: SS2875ES

• Assess the community's level of knowledge and awareness regarding locally developed vaccines.
• Explore trust and willingness of the community to utilise locally developed vaccines.
• Identify factors contributing to positive or negative perceptions of locally developed vaccines.
• Explore the most effective communication channels for sharing information about locally developed vaccines.

 Uganda 2024-08-26 18:25:34 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
ASUMAN KHAMIS SHAFI
ID:
Timing Of Neurosurgical Intervention And Short-term Outcome Of Patients With Traumatic Brain Injury Admitted To Mulago Hospital Emergency Department
REFNo: HS4610ES

1. To determine the average decision-to-intervention time among patients with TBI admitted at MNRH ED. 2. To determine factors associated with the neurosurgical intervention among patients with TBI admitted to the MNRH ED. 3. To determine the 72-hour outcome mong patients with TBI requiring neurosurgical intervention admitted to MNRH ED.
 Uganda 2024-08-26 18:24:09 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
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