Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Docus Alowo
ID: UNCST-2022-R010834
Prebiotic and probiotic capacity of ready-to-use composite foods developed from non-starch polysaccharides plant-based sources
REFNo: A226ES

Determine the strains with probiotic potential in fermented foods using composite flours ,Determine the microbial diversity of foods fermented using composite flours ,Determine the prebiotic capacity of the Fermentable oligo-di-mono-saccharides and polyols (FODMAPS) in plant based composite flours ,1) Identify Fermentable oligo-di-mono-saccharides and polyols in plant-based composite flours,To determine prebiotic and probiotic capacity of fermented foods developed using millet-sesame-soy composite flour,
Uganda 2022-09-06 14:32:11 2025-09-06 Agricultural Sciences Non-Clinical Trial Degree Award
Paul Kitandwe Kato
ID:
Evaluation of the immunogenicity of candidate Rift Valley fever self-amplifying RNA vaccines in laboratory mice
REFNo: HS2408ES

To evaluate the humoral immune responses in mice of candidate saRNA vaccines encoding RVFV Gn and Gc sequences using a naked VEEV vector design To evaluate the cell-mediated immune responses in mice of candidate saRNA vaccines encoding RVFV Gn and Gc sequences using a naked VEEV vector design
Uganda 2022-09-06 14:30:17 2025-09-06 Medical and Health Sciences Non-Clinical Trial Degree Award
Kenneth Odur
ID:
Assessing Community Perceptions on the State of Nutrition in Uganda. Focus Group Discussions and Key Informant Interviews in Lira District.
REFNo: SS1385ES

To impact malnutrition on the national and international level through research and dissemination.,To equip youth ambassadors in Ayami with knowledge and experience conducting qualitative research through focus groups and key informant interviews.,To equip community members in Ayami sub county with increased knowledge of the causes and consequences of malnutrition, as well as positive behaviors and resources to address malnutrition.,To assess community knowledge, attitudes, and beliefs on malnutrition and current malnutrition interventions.,To qualitatively assess implementation of the Uganda Nutrition Action Plan in Ayami sub county, Lira District.,
Uganda 2022-09-06 14:29:01 2025-09-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charles Kiyaga
ID:
A Validation Study to Compare the Performance of Gazelle Point-of-Care Device with Isoelectric Focusing and Capillary Electrophoresis in testing for Sickle Cell Disease in Uganda
REFNo: HS2319ES

c) To assess the usability and operational characteristics of Gazelle, including the ease of use, technical complexity and inter-reader variability.,b) To evaluate foetal haemoglobin (HbF) quantitation in SCD patients on hydroxyurea treatment, as compared to standard methods, in Uganda.,a) To determine the sensitivity and specificity of Gazelle in comparison to the standard tests used for the diagnosis of SCD.,
Uganda 2022-09-06 14:24:20 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Enhancing the capacity of Community Health Workers on epidemic and pandemic preparedness and response in Wakiso district, Uganda: impact evaluation and dissemination
REFNo: HS2349ES

Overall objective To carry out an impact evaluation of a recent project that enhanced the capacity of Village Health Teams (VHTs) on epidemic and pandemic preparedness and response (including COVID-19) in Wakiso district so as to generate information to enhance scale-up of interventions as well as inform future related activities. Specific objectives 1. To explore how the performance of VHTs in relation to epidemic / pandemic preparedness and response including COVID-19 was affected by the training. 2. To explore other effects of the training on epidemic / pandemic preparedness and response including COVID-19 to VHTs and their communities.
Uganda 2022-09-06 14:22:51 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Estimating the real-world effectiveness and determinants of effectiveness China Manufactured and other COVID-19 vaccines in Uganda
REFNo: HS2422ES

To determine the overall and product-specific rate of breakthrough infections (laboratory-confirmed SARS-CoV-2) among adult Ugandans vaccinated with China manufactured and other COVID-19 vaccines in Uganda,To estimate COVID-19 vaccine effectiveness (CVE) for more severe outcomes (e.g., ICU admission, or in-hospital mortality) and its determinants in among adults diagnosed with COVID-19 in Uganda,To determine the overall and product-specific effectiveness of China manufactured and other COVID 19 vaccines against symptomatic COVID-19 disease among adults diagnosed with COVID 19 in Uganda,
Uganda 2022-09-06 14:21:36 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Wauyo
ID: UNCST-2022-R010247
HOLISTIC MODEL FOR PREDICTING USER ADOPTION MECHANISM OF MOBILE APPLICATIONS FOR BUSINESS GROWTH IN MEDIUM ENTERPRISES: THE CASE OF KAMPALA CITY COUNCIL AUTHORITY
REFNo: SIR136ES

4. To propose a holistic model for predicting user adoption of mobile applications at KCCA,3. To test and validate the proposed model at KCCA,2. To determine factors that influence users intentions to adopt mobile applications at KCCA,1. To assess the existing mobile applications user adoption at KCCA.,The main research objective of this thesis is to “explain the mobile application adoption mechanism in the market and also build a holistic model that predicts user’s adoption of the third party mobile applications at KCCA.,
Uganda 2022-09-06 14:20:08 2025-09-06 Engineering and Technology Non-Clinical Trial Degree Award
Roy Mayega William
ID: UNCST-2022-R010983
Composition of honey sold on the Kampala market and its glycemic response among diabetic patients.
REFNo: HS2286ES

1) To characterise the carbohydrate composition of locally produced honey on the Kampala market.
2) To determine the organic composition of locally produced honey on the Kampala market.
3) To assess the Glycemic index of diabetic patients subjected to locally produced honey.


Uganda 2022-09-06 14:18:12 2025-09-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gorretti Nassali
ID:
A PHASE III, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF ADJUVANT GIREDESTRANT COMPARED WITH PHYSICIAN'S CHOICE OF ADJUVANT ENDOCRINE MONOTHERAPY IN PATIENTS WITH ESTROGEN RECEPTOR?POSITIVE, HER2 NEGATIVE EARLY BREAST CANCER
REFNo: HS2133ES

Primary objective:
To demonstrate superiority of giredestrant over the control treatment
Secondary objectives:
1. To evaluate the efficacy of giredestrant compared with TPC
2. To evaluate the safety of giredestrant compared with TPC
3. To characterize giredestrant pharrmacokinetics (PK)
4. To evaluate health status utility scores of participants treated with giredestrant compared with TPC
5. To evaluate the efficacy of giredestrant compared with TPC
6. To evaluate the tolerability of giredestrant compared with TPC
7. To identify and/or evaluate biomarkers that are predictive of response to giredestrant
Uganda 2022-09-06 14:14:37 2025-09-06 Medical and Health Sciences Clinical Trial Non-degree Award
Mary Gorreti Nabbosa
ID:
Application of the IFLA code of ethics for librarians in selected academic universities in Uganda
REFNo: SS1372ES

i. To identify the services offered by Kyambogo University and Uganda Christian University libraries.

ii. To examine the ethical practices of librarians in Kyambogo University and Uganda Christian University libraries.

iii. To investigate whether Kyambogo University and Uganda Christian university librarians have applied the IFLA code of ethics in library and information service delivery.

iv. To determine the challenges faced by librarians Kyambogo University and Uganda Christian University libraries when applying the IFLA code of ethics in the library and information service delivery.
Uganda 2022-08-30 17:24:16 2025-08-30 Social Science and Humanities Non-Clinical Trial Degree Award
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