Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
David Musoke
ID:
Integrated malaria prevention in Wakiso district, Uganda: an implementation study
REFNo: HS2270ES

Broad objective
To conduct implementation research on integrated malaria prevention in Wakiso district using photovoice as a participatory action research methodology so as to generate information required for implementation of the RCT in future.


Specific objectives
1. To assess the extent of implementation of the various methods in integrated malaria prevention.
2. To explore facilitators and barriers to implementation of the various methods in integrated malaria prevention individually and holistically.

Uganda 2022-06-28 17:05:03 2025-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Eyul
ID:
Wheels of Change? Exploring 'Bicycles for Development' for Women and Girls in the (Post-)Pandemic Contexts of Canada, Uganda and Nicaragua
REFNo: SS1274ES

1. To assess the impact and activities of BFD programming on gender inequality, development, mobility, social entrepreneurship, and the environment.

2. To investigate the efficacy of a trauma-and-violence-informed approach, and the use of participatory mapping and visual research methods within a south-south framework to improve program sustainability, impact and effectiveness.

3. To understand how BFD programs and access to bicycles contribute to lessening, augmenting, and/or exacerbating gender-based inequalities in (post-)pandemic life.

4. To explore the strategies and approaches that BFD programs for women and girls take with respect to: a) GBV prevention; b) social entrepreneurship; and c) environmental sustainability promotion.

5. To examine the contextual factors – such as COVID-19, the ‘shadow pandemic’ and the emerging impacts of ‘green recovery’ – that shape a) the work of BFD nongovernmental organizations; and b) their efforts at achieving gender equality through BFD work.

Uganda 2022-06-28 17:04:08 2025-06-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
DICKSON KALUNGI
ID:
AN ONTOLOGY-BASED MODEL FOR EFFECTIVE CAREER GUIDANCE
REFNo: SIR83ES

1. To establish the requirements for developing an Ontology model for effective Career Guidance
2. To design and develop Ontology sub-models that support 21st century career guidance Services
3. To integrate the developed sub-models into an Ontology model for effective career guidance
4. To evaluate the integrated Ontology model
Uganda 2022-06-28 17:01:19 2025-06-28 Engineering and Technology Non-Clinical Trial Degree Award
Naome Wandera Namakula
ID:
Assessing the social and economic impact of COVID-19 on women working in the informal urban economy in Uganda (SPH2022-223)
REFNo: SS1323ES

i) To investigate how COVID-19 policies impacted pre-existing gender inequalities, including GBV/SRH among women workers in informal urban economies. ii) To understand the coping and resilience strategies of IWWs in the context of the pandemic and its effects. iii) To assess women's GBV and SRH experiences, including access to related services during the COVID-19 pandemic.
Uganda 2022-06-28 16:53:23 2025-06-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda (Experimental Phase)
REFNo: SS1324ES

The study objectives are as follows:
1. To determine whether business relocation within Kampala can increase profits for mobile microentrepreneurs (primary objective)
2. To identify which constraints might restrict microentrepreneurs’ business locations within the city by separately relieving information and liquidity constraints (secondary objective)
USA 2022-06-28 16:47:30 2025-06-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Khamisi Musanje
ID: UNCST-2021-R012863
Challenges of engaging District Local Governments and Implementing Partners in the District Health Planning Process, a case study of Northern Uganda. A mixed method study
REFNo: HS2314ES

• To identify health implementing partners and their areas of intervention in the selected districts in Acholi and Lango sub-regions of Uganda.
• To determine the level of involvement of health implementing partners and the district health management teams in the development of the district health annual work plan.
• To assess factors influencing the involvement of health implementing partners and the district health management teams in the development of the district comprehensive health annual work plan in the financial year.

Uganda 2022-06-28 16:45:56 2025-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
CHOICE-BASED PrEP DELIVERY FOR TRANSGENDER PEOPLE IN UGANDA
REFNo: HS2316ES

Aim 1: Identify PRECEDE factors that influence PrEP implementation for transgender people in Uganda.

Guided by the PRECEDE-PROCEED model, which is widely used for public health interventions, we will analyze previously collected qualitative data from four TGP studies and also conduct two new focus groups with TGP and providers to identify predisposing, reinforcing, and enabling factors that may impact implementation of choice-based PrEP. A stakeholder workshop anchored in good participatory practice will discuss results of the qualitative research and guide design of the optimal choice-based PrEP delivery model for Aim 2.

Aim 2: Offer PrEP choice to transgender people in a DSD model and evaluate implementation and effect on PrEP use (PROCEED).

We will offer choice of CAB-LA or oral PrEP, and choice of facility or community delivery (with option to switch), to 300 HIV-negative TGP with follow-up for 24 months. Adverse events, product switching, and trajectories of choice over time will be monitored and documented. Persistence on CAB LA and oral PrEP will be compared during the choice period, and with a historical cohort without PrEP choice (ClinicalTrials.gov, NCT04491422). Primary outcomes are choice of PrEP option & delivery model, adherence, and persistence.

Aim 3: Use mixed methods to evaluate how choice influences PrEP use among TGP (PROCEED).
Inductive and deductive analyses based on in-depth interviews with purposively sampled PrEP users (n=50) and providers (n=10) will be used to explain “how” and “why” choice did or did not work and interpret implementation data from Aim 2. Choice preferences will be assessed via structured questionnaires.

Aim 4: Estimate cost implications associated with integrating CAB LA into HIV programs.
We will conduct health system versus client cost analyses to inform budgeting. Costs incurred and averted will be estimated using activity-based micro-costing, study budget, and the literature. Costs and modeled outcomes will be combined to estimate budget impact with PrEP persistence at 6 and 12 months.


Uganda 2022-06-28 16:44:09 2025-06-28 Medical and Health Sciences Clinical Trial Non-degree Award
Victor Musiime
ID: UNCST-2021-R013794
Building Resources to Assess Impaired Neurocognition in Children with HIV in Low and Middle Income Countries (BRAIN Child LMICs)
REFNo: HS2271ES

(1) Adapt NeuroScreen for Luganda-speaking children 5-12 years. (a) Through expert focus groups and multiple rounds of cognitive interviewing with children, determine necessary adaptations to make the NeuroScreen tests valid, acceptable and understandable to Luganda-speaking children, (b) implement
those adaptations in the app, (c) re-evaluate the adapted app with children, (d) examine its acceptability by clinical staff most likely to administer it, and (e) make further adaptations, as needed.

(2) Examine construct validity of the child version NeuroScreen tests. (a) Compare NeuroScreen test performance to gold standard neuropsychological test battery performance among Ugandan children 5-12 years with and without HIV, and (b) explore the relationship between performance on NeuroScreen and behavioral health.


Uganda 2022-06-28 16:42:46 2025-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sophie Riddick
ID: UNCST-2022-R010576
Decision-making and religious beliefs across cultures
REFNo: SS1336ES

study how children learn about religious beliefs and practices over development, gain an understanding of how children attend to normative information presented by a peer or by an adult
UK 2022-06-28 14:39:43 2025-06-28 Social Science and Humanities Non-Clinical Trial Degree Award
ERICK SSEGUJJA
ID: UNCST-2021-R012964
Donor transition and its effect on health coverage in Uganda
REFNo: HS2112ES

The aim of this study is to better understand how and why Uganda has (or not) been able to sustain effective coverage of health interventions after projects previously funded by donors ended and the enablers and barriers encountered in this,4. Identify health system adaptation strategies devised by (sub)national actors for sustaining coverage of the two selected interventions when donor projects ended from 2016-2017 to date.,3. Understand how the end of project funding affected the coverage of maternal health interventions and HIV services in case-study districts in 2016 and 2017 respectively.,2. Determine changes in (i) select maternal health indicators (ii) key HIV service indicators three years after the end of project funding between 2016 and 2017 in select donor- supported districts.,1. Explore the political, financing and health system factors that influenced whether coverage of maternal health interventions and HIV services were sustained once the projects funded by the donors ended between 2016 and 2017. ,
Uganda 2022-06-27 8:45:40 2025-06-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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