Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Deborah Kirabo
ID: UNCST-2025-R022547
Documentation of RAHU Peer Education Model
REFNo: SS4727ES

Objective 1: To comprehensively document RAHU\'s Peer Education Model design, implementation mechanisms, and operational approaches across five regions (Kampala, Kasese, Adjumani, Busoga, and Sebei) from 2014 to present

Objective 2: To assess the peer education model\'s performance against its three core program objectives: (a) improving young people\'s access to SRHR information for informed decision-making, (b) reducing risks and promoting individual and collective empowerment about sexual and reproductive health, and (c) strengthening interpersonal communication skills for peer-to-peer SRHR communication

Objective 3: To analyze implementation challenges, success factors, regional adaptations, and lessons learned to generate evidence-based recommendations for model replication, scaling, and policy advocacy.
Uganda 2026-02-18 12:43:08 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Martin Okello
ID: UNCST-2025-R020344
INVESTIGATION OF PLANT-BASED MOSQUITO REPELLENTS FOR VECTOR-BORNE DISEASE CONTROL, ESPECIALLY MALARIA IN RURAL UGANDA: A MIXED METHODS APPROACH
REFNo: HS7051ES

4. To gain more understanding through existing literature/research about Lantana camara (LC) plants and other repellent/herbal plants in relations to vector borne diseases, especially malaria control/prevention in rural Uganda.
5. To collect information regarding attitude, knowledge, beliefs, and behaviours about Lantana camara (LC) plants and possibly other repellent plants in relation to malaria prevention in rural Uganda.
6. To explore factors associated with implementing the use of plant-based repellent products like Lantana plant extracts or other repellant plants as alternatives to control or prevent malaria in rural Uganda, including the feasibility, acceptability and sustainability of such approaches.

Uganda 2026-02-18 12:32:51 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
raymond Kihumuro bernard
ID: UNCST-2021-R013303
Depression Assessment in Adolescents and Young People Living with HIV in Uganda using Interactive Voice Response (DAIVR): A Pilot Feasibility Study
REFNo: HS7107ES

2. Evaluate the feasibility, acceptability, performance, and screening yield of DAIVR.,1. Explore healthcare workers’ (HCW) and AYPLHIV’s preparedness for integrating IVR-based PHQ-2 screening into routine care.,
Uganda 2026-02-18 12:28:27 2029-02-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
Quality of life in postoperative neurosurgical patients: decompressive hemicraniectomy with delayed cranioplasty versus hinge craniotomy in low-resource settings
REFNo: HS6653ES

Provide Recommendations: Develop evidence-based guidelines for surgical practices in resource-limited settings, prioritizing interventions that optimize long-term QoL,Analyze Contextual Factors: Identify patient and caregiver demographic and clinical factors influencing QoL outcomes.,Evaluate Caregiver Impact: Examine how the two surgical interventions affect caregiver QoL, including their psychological well-being and caregiving burden.,Assess QoL: Use modifications of validated surveys (e.g., Neuro-QoL surveys) to evaluate physical, cognitive, emotional, and social QoL outcomes in patients.,To compare and evaluate the long-term QoL outcomes of patients undergoing DHC without cranioplasty and HC, focusing on physical, cognitive, emotional, and social domains, as well as the perspectives of their caregivers​.,
Uganda 2026-02-18 12:22:28 2029-02-18 Medical and Health Sciences Non-degree Award
moiti MoitiEriya
ID: UNCST-2024-R016141
LIFE HISTORY TRAITS OF VARROA MITE (Varroa destructor) AND ITS EFFECT ON HONEYBEE COLONY PERFORMANCE IN SELECTED AGRO-ECOLOGICAL ZONES IN UGANDA
REFNo: NS1167ES

To determine the effect of Varroa infestation levels on colony performance of Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess the effect of honeybee hygienic behavior and swarming behaviour on Varroa infestation levels in Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess life history traits of Varroa mites infesting Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To assess temporal Varroa infestation levels in Apis mellifera colonies in Lake Victoria crescent and the Eastern agro-ecological zones of Uganda.,To evaluate Varroa reproductive success so that its impact on honeybee colony performance is established.,
Uganda 2026-02-18 12:20:50 2029-02-18 Natural Sciences Non-Clinical Trial Degree Award
Mark Jordans
ID: UNCST-2020-R014861
MENTAL HEALTH SYSTEMS AND A MENTAL HEALTH CARE PACKAGE FOR CHILDREN IN SELECTED REFUGEE SETTLEMENTS IN UGANDA (PAMOJA TUNAWEZA): PARTICIPATORY SYSTEM DYNAMICS AND CLIENT JOURNEYS
REFNo: SS4795ES

Objectives: 
This study aims to identify and evaluate key factors affecting the implementation and performance of a mental health care system in real-world settings.
Specific Research objectives and research questions:
1. To assess how well the mental health care system integrates and is compatible with existing mental healthcare services, infrastructure, and practices, both formal and informal with a particular focus on adolescent mental health.  
Research Question 1: Exploring how the mental health care system integrates, or is compatible, with existing mental health systems for adolescent mental health

2. To examine client experiences within the care system and identify opportunities to optimize service delivery and outcome.
Research Question 2: Evaluating the client experience, how this can be optimized within the care system

Netherlands 2026-02-18 12:19:41 2029-02-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Bernard Mwesigye
ID: UNCST-2024-R016003
Delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emmergency Unit of Mbarara Regional Referral Hospital
REFNo: HS6376ES

General:To assess the proportion of patients with delayed Door-to-Doctor time and associated factors among high acuity patients at the Accidents and Emergency Unit at Mbarara Regional Referral Hospital.
Specific objectives:
•To determine the proportion of high acuity patients with delayed Door-to-Doctor time at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.
●To determine the factors associated with delayed Door-to-Doctor time of high acuity patients at the Accidents and Emergency Unit of Mbarara Regional Referral Hospital.

Uganda 2026-02-18 12:16:08 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
LONG TERM CARDIAC AND PULMONARY CONSEQUENCES OF TB (LONG TB)
REFNo: HS6945ES

Establish a sample repository for future: a) host and M.tb whole genome sequencing for genome wide association studies, b) non-targeted multi-omic (transcriptome, proteome, metabolome) analysis and, c) targeted inflammatory/immunological pathway analysis,Characterize the prevalence, clinical presentation, and progression of sub-clinical CVD – a surrogate measure for subsequent PTCVD risk – among successfully treated adult drug-sensitive pulmonary TB cases,Characterize the prevalence, clinical presentation, and progression of PTLD among successfully treated adult drug-sensitive pulmonary TB cases,The overarching goal of this proposal is to establish a well characterized cohort of pulmonary TB patients with prospective cardio-pulmonary assessments and sample repository during and after treatment for comprehensive clinical phenotyping and immunological endotyping of post-TB sequelae,
Uganda 2026-02-18 12:14:31 2029-02-18 Medical and Health Sciences Non-degree Award
Natalia Marina Maure Marina
ID: UNCST-2024-R003148
Burden of cardiovascular disease risk factors among patients with tuberculosis in the karamoja sub-region of uganda. A cross-sectional survey
REFNo: HS6547ES

Primary objective: •Estimate the burden of CVD risk factors among TB patients at Matany and Moroto hospitals Secondary objectives: •Compare the burden of CVD risk factors between TB patients at Matany and Moroto hospitals and the burden of CVD risk factors in the Ugandan general population •Contrast the burden of CVD risk factors among TB inpatients and outpatients •Secondary Endpoint 2: Prevalence of CVD risk factors in TB inpatients and outpatients •Determine the 10-year cardiovascular event risk using the WHO/ISH risk prediction charts •Describe the associations between TB disease characteristics (pulmonary vs. extrapulmonary, drug-resistant vs. drug-susceptible, HIV co-infection status) and cardiovascular risk profiles
Italy 2026-02-18 12:13:03 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Abias Asiimwe Katesigwa
ID: UNCST-2025-R022247
Quality Improvement Strategies in Private Healthcare Facilities in Uganda
REFNo: HS7033ES

General Objective:
The primary purpose of this study is to investigate how Quality Improvement (QI) strategies become institutionalised within Uganda's private health facilities, examining the processes, factors, and outcomes that enable QI practices to transition from externally-driven initiatives to internally-sustained organisational norms.
Specific Objectives:
1. To identify and evaluate Quality Improvement (QI) strategies employed by private health facilities to enhance care quality.
2. To analyse the processes and critical factors influencing the institutionalisation of QI initiatives as a cultural norm within private health facilities, including challenges and strategies for their mitigation.
3. To assess the return on investment (ROI) of QI initiatives, focusing on their impact on care quality and operational efficiency in private health facilities.
4. To explore patients' perceptions and experiences regarding the quality of health services delivered by private health facilities.
5. To develop strategic recommendations for the institutionalisation of Quality Improvement (QI) initiatives within healthcare systems and to enhance care quality in the private health sector, informed by expert review and validation.

Uganda 2026-02-18 12:12:04 2029-02-18 Medical and Health Sciences Non-Clinical Trial Degree Award
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