Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Atwebembeire John Mushomi
ID: UNCST-2025-R022006
Evaluation of the ASRH Gatherings for Young Mother Gardeners Program
REFNo: SS4584ES

To assess the short- and medium-term impacts of the ASRH Gatherings and integrated livelihood support on young mothers in Kasese District.1. i. Examine how the program addresses challenges faced by adolescent mothers. 2. ii. Document transformative changes in participants’ lives, including aspirations, health, and livelihoods. 3. iii. Provide evidence-based recommendations for strengthening and scaling the program.
Uganda 2025-12-01 21:05:46 2028-12-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Doreen Nakagaayi
ID: UNCST-2023-R006587
Rheumatic Heart Disease among Pregnant women in Northern Uganda: Prevalence, Impact on Pregnancy Outcomes and Strategy for Early Identification.
REFNo: HS6717ES

General Objectives
To determine the prevalence of RHD in pregnancy in Northern Uganda, the maternal and fetal outcomes and use this data to develop and validate clinical risk scores that predict presence of RHD in pregnancy and those at increased risk for adverse maternal outcomes.
Specific Objectives
Objective 1
A. To determine the prevalence of RHD among pregnant women in a community setting in Northern Uganda.
B. To design a diagnostic risk score that predicts presence of RHD in early pregnancy in Northern Uganda
Objective 2
A. To determine the maternal, and fetal outcomes of pregnant women with RHD in a community setting in Northern Uganda.

Uganda 2025-12-01 20:59:51 2028-12-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Peter Cromwell Okello
ID: UNCST-2025-R021939
Rethinking the Potential of Formal Education in Buttressing the Peace–Economic Development Nexus among Karamojong Pastoralists in Moroto District, Uganda.
REFNo: SS4615ES

The study aims to critically examine the interconnections between formal education, peacebuilding, and economic development among the Karamojong pastoralist communities in Moroto District, Northeastern Uganda. Specifically, it seeks to understand how formal education can be strategically leveraged to promote social cohesion, gender equity, and sustainable livelihoods, while interrogating the socio-cultural, political, and economic dynamics that influence its implementation and outcomes.
Anchored in Pierre Bourdieu’s Theory of Practice, the study explores how education operates as both a field of social reproduction and a potential catalyst for transformation within a historically marginalised pastoralist society.
Research Objectives:
To realise the overarching aims of the study, the following research objectives have been framed:
1. To explore how Karamojong pastoralists experience and perceive access to formal education across different levels (primary, secondary, tertiary, and vocational), focusing on the social, cultural, economic, and geographical factors that shape participation and exclusion.
2. To examine the extent to which formal education, in its current form and cultural relevance, contributes to conflict mitigation, peacebuilding, social cohesion, and economic resilience among Karamojong pastoralists.
3. To analyse how the socio-cultural, political, and economic characteristics of the Karamojong people influence the formulation and implementation of educational policies and strategies within their region.
4. To investigate how formal education shapes gender relations, power dynamics, and opportunities for both women and men in the Karamojong community, particularly in relation to peacebuilding and economic development.
5. To co-develop culturally relevant educational strategies and curriculum innovations that integrate indigenous knowledge and support peacebuilding, gender equity, and sustainable development in pastoralist contexts.
6. To formulate evidence-based policy recommendations that align educational policies and practices with the socio-cultural realities, aspirations, and economic needs of the Karamojong pastoralist communities.
Uganda 2025-12-01 20:53:21 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Assessing Willingness to Pay (WTP) for Family Planning Products in Uganda: Insights into consumer demand and affordability
REFNo: HS6749ES

Study Aim:
The overall aim of this study is to assess and understand the factors influencing willingness to pay for the different FP products in the Ugandan Market and barriers to WTP for the contraceptive’s products from all key stakeholders in the current market. Development of the study aims was guided by a series of consultative meetings with key stakeholders including program implementers and review of the recent literature on WTP studies. The study generates evidence to fill key gaps identified from the previous studies conducted on WTP focusing on the underlying factors to client WTP for FP products and services.
1.4 Specific Objectives:
1. To assess the current willingness to pay for Family Planning products among different population segments in Uganda.
2. To identify socio economic and demographic factors influencing willingness to pay for contraceptives
3. To integrate findings from previous WTP studies to provide a comprehensive -analysis and holistic understanding of pricing dynamics.
4. To identify key factors influencing pricing decisions, including cost-to-delivery and market affordability.

Uganda 2025-12-01 20:44:08 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Akampurira
ID: UNCST-2025-R019367
Stakeholder Engagement, Entrepreneurship Education, and Entrepreneurial Intention among Business Graduates of Chartered Universities in Southwestern Uganda
REFNo: SS4425ES

1. To determine the relationship between stakeholder engagement and entrepreneurial intention among university business graduates. 2. To assess the relationship between stakeholder engagement and entrepreneurship education among university business graduates. 3. To evaluate the relationship between entrepreneurship education and the entrepreneurial intention of university business graduates. 4. To analyse the mediating role of entrepreneurship education on the relationship between stakeholder engagement and entrepreneurial intention among university business graduates.
Uganda 2025-12-01 20:37:44 2028-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Assessment of Nasal Microbiome, Inflammatory Markers, and Infectious Agents among individuals with Biomass Fuel COPD in Uganda ACRONYM: ASCENT–NASAL Study
REFNo: HS6748ES

Aim 1: Characterize the nasal microbiome composition among individuals with and without COPD who
have different levels of air pollution exposure.

Aim 2: Assess nasal inflammatory marker differences among individuals with and without COPD who
are exposed to different levels of air pollution.

Aim 3: Determine the prevalence of viral and bacterial respiratory pathogens among individuals with
and without COPD and their association with PM2.5 exposure.
Uganda 2025-12-01 14:33:20 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Safety, preliminary efficacy, and Pharmacokinetics of Herbal/Natural/ Traditional therapeutic products for the management of Diabetes Mellitus in Uganda.
REFNo: HS6530ES

Main Objective
1. To evaluate the safety, effectiveness and pharmacokinetics of 3 selected NDA- notified herbal/natural/traditional therapeutic products in Uganda, designated IMP1, IMP2, and IMP3.
2. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of natural therapeutics in Uganda.

Specific Objectives
1. To determine the efficacy of selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the treatment of diabetes mellitus in adult patients in Uganda
2. 2. To assess the effect of the selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) on specific cardio-metabolic characteristics of adult patients with DM in Uganda.
3. To assess clinical and laboratory adverse events associated with selected NDA- notified herbal/natural/traditional therapeutic products, specifically IMP1, IMP2 and IMP3 in adult patients with DM in Uganda.
4. To investigate the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.
5. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of herbal/natural/traditional therapeutics in Uganda.e the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.

Uganda 2025-12-01 14:19:22 2028-12-01 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Matovu Wasswa
ID: UNCST-2025-R021145
Understanding Power, Institutions, and Policy Dynamics: A Political Economy Analysis of Youth Employment in Uganda
REFNo: SS4607ES

Research Questions The political economy analysis aims to answer two overarching research questions: I. How can current policies and regulatory frameworks be activated and enhanced to provide dignified and fulfilling work opportunities for youth in Uganda? II. What industrial and trade policies and/or plans will enable Uganda to leverage its demographic transition, the 4th industrial revolution, and the evolving digital economy to create adequate opportunities for dignified and fulfilling work for Ugandan youth? Purpose and Objectives The main purpose of this study is to examine how political, institutional, and economic structures interact to shape youth employment outcomes in Uganda. Specifically, the research seeks to: • Map the formal and informal policy, regulatory, and institutional frameworks governing youth employment. • Analyse the interests, incentives, and power dynamics of key actors who influence or obstruct youth employment reforms. • Understand the lived experiences, perceptions, and aspirations of young people in relation to work, inclusion, and voice. • Identify enablers and constraints to the implementation of effective and inclusive employment strategies. • Generate context-sensitive, actionable recommendations for policy and institutional reform.
Uganda 2025-11-26 14:32:03 2028-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sarah Wilker
ID: UNCST-2025-R019791
One size fits all? Towards individual prediction of treatment success for posttraumatic stress disorder in post-conflict settings (TRAUMA-FIT)
REFNo: HS6712ES

Main Objective 1. to identify individual predictors of treatment response to two different treatments in survivors with PTSD in a post-conflict setting Specific Objectives 1. Investigate whether NET is, on average, more effective than PM+ for the treatment of PTSD 2. Identify predictors of optimal response in the two conditions, and thereby identify predictors of treatment success in a trauma-focused versus present-focused treatment 3. Investigate the explanatory role of socio-ecological factors in PTSD treatment response
Germany 2025-11-26 14:28:24 2028-11-26 Medical and Health Sciences Clinical Trial Degree Award
Pamela Atim
ID: UNCST-2020-R014964
Effects of biomass fuel usage on indoor air quality and associated respiratory health of women and children in Northern Uganda
REFNo: HS6606ES

1.To analyse the trends of biomass fuel usage in Uganda from 2001 to 2022. 2.To determine the factors associated with respiratory symptoms among women and children in rural and urban areas of Northern Uganda. 3.To quantify the levels of personal exposure of women to air particles (PM2.5, PM10) in the different micro-environments. 4.To explore the perspectives of the community and stakeholders regarding the impacts of cooking fuels.
Uganda 2025-11-26 14:26:18 2028-11-26 Medical and Health Sciences Non-Clinical Trial Degree Award
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