Grace Ahimbisibwe Miriam
ID: UNCST-2021-R012129
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Establishing Surveillance for Serious Neonatal Infections in sub-Saharan Africa (SNIP-Africa) Version 2.0 dated 15 Aug 2024
REFNo: HS5614ES
General Objective
To establish capacity and methods to conduct surveillance of neonatal BSI, pathogen and antimicrobial susceptibility profiles, AMR colonisation prevalence (patient and hospital environment) and antibiotic prescribing trends among hospitalised neonates (?28 days) in sSA neonatal units.
Specific Objectives
i. To set up a surveillance network and define methods to support continuous epidemiological evaluation of neonates with suspected sepsis in participating sSA neonatal units.
ii. To create a streamlined, translatable data capture approach for use across a range of healthcare facilities.
iii. To determine the personnel and physical resources required for ongoing surveillance in different settings.
iv. To develop a real time data dashboard driving quality improvement through surveillance at the level of participating sites.
v. To describe AMR burden and patterns and identify trends in resistant bacterial invasive and carriage isolates in participating units and participants.
vi. To pilot assessment of colonization pressure and the relationship between invasive blood culture isolates, faecal carriage, the hospital environment and antimicrobial usage.
vii. To develop tools to detect and monitor outbreaks within participating neonatal units.
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Uganda |
2025-04-11 14:17:57 |
2028-04-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Edgar Mulogo Mugema
ID: UNCST-2023-R008170
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HIV-Associated Viral Acute Respiratory Tract Illness (HAVARTI): The burden and severity of vaccine-preventable respiratory infection in people living with HIV in rural Uganda.
REFNo: HS5676ES
Primary Objective
The overarching goal of this study is to define the incidence and relative frequency of, and severity of illness from, influenza and two other vaccine-preventable viral respiratory infections, respiratory syncytial virus (RSV) and SARS-CoV-2, among people living with HIV (PLWH) in rural Uganda.
Specific Aims
1. Determine the incidence of ARI in a cohort of individuals living with HIV in rural Uganda and the proportion and incidence of those ARI episodes caused by vaccine-preventable viral respiratory infections (influenza, RSV, and SARS-CoV-2). We will enroll adolescents and adults infected with HIV who receive care at the Antiretroviral Therapy (ART) clinic at Bugoye Health Centre (BHC), a rural peripheral health facility in western Uganda. Participants will self-collect a mid-turbinate nasal swab at the onset of every episode of ARI during the study follow-up period. Samples will be tested for RSV, influenza, and SARS-CoV-2 within 48 hours of collection using a molecular assay.
2. Estimate the morbidity and mortality from influenza, RSV, and SARS-CoV-2 in this same population of PLWH. Study staff will conduct home visits 14 days after the onset of each episode of ARI to assess outcomes. Specifically, they will record any antibiotic or other treatment taken and its source (e.g., purchased at drug shop or prescribed by a healthcare provider); missed days of work (e.g., in the field for subsistence farmers); care-seeking including outpatient visits and inpatient admissions; and vital status.
3. Explore risk factors for severe disease from influenza, RSV, and SARS-CoV-2 among PLWH. As an exploratory aim, we will collect information on demographics, household and socioeconomic factors, cooking methods, past medical history including presence of underlying lung disease, smoking status, and history of pneumonia or tuberculosis, nadir and last CD4 count, most recent HIV viral load (VL) and VL at diagnosis, and ART history.
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Uganda |
2025-04-11 14:15:22 |
2028-04-11 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Ouma Simple
ID: UNCST-2021-R012820
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Harnessing Parental Social Networks to Increase HIV Testing Uptake Among Children of At-Risk Parents in Uganda: A Parallel-Group, Two-Arm Quasi-Experimental Implementation Science Protocol
REFNo: HS5741ES
Objectives:
Main Objective
To Adapt, implement and evaluate maternal SNS to improve access to HIV testing services among children of FSW.
Specific Objectives
1. To adapt SNS that harnesses maternal SN for HIV testing in children of female sex workers
2. To implement the adapted HASHTAG intervention targeting CARP in Gulu City
3. To evaluate the effectiveness and implementation science outcomes of the HASHTAG project
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Uganda |
2025-04-11 14:13:08 |
2028-04-11 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Davis Hafashimana Simon
ID: UNCST-2025-R018006
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An investigation into the variability of Hemileia vastatrix on Robusta coffee in Uganda
REFNo: A591ES
Objectives
1. To assess the genetic diversity of Hemileia vastatrix on Robusta coffee in Uganda
2. To make a linkage of any observed diversity to disease distribution in Uganda
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Uganda |
2025-04-11 14:11:00 |
2028-04-11 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Venantius Bbaale Kirwana Bbaale
ID: UNCST-2024-R002370
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RISKY SEXUAL BEHAVIOUR AMONG YOUNG PEOPLE IN UGANDA’S ISLANDS, AN ANALYSIS OF SEXUALITY INFORMATION SOURCES AND COMPLETENESS.
REFNo: SS3785ES
4-Evaluate the level of completeness of sexuality information from various sources to young people in Uganda\'s island communities,3-Compare current and preferred sources of sexuality information sources among young people in the Uganda Island communities,2-Assess the barriers young people in island communities face in accessing sexuality information from different sources.,1-Explore young people’s perceptions of risky sexual behavior in the Uganda Island communities.,Examine young people’s perceptions of risky sexual behavior and how sexuality information sources and completeness influence sexual behavior, in Uganda Island communities.,
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Uganda |
2025-04-11 14:09:55 |
2028-04-11 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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