Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Florence  Nansumbi
ID:
Functional Indicators to assess freshwater ecosystem integrity: Biogeochemical dynamics of carbon, nitrogen and phosphorous cycling and stream metabolism
REFNo: NS402ES

The aim of this study is to evaluate the ecological status of sections of a Ugandan river with different levels of human impact using stream metabolism as a functional indicator.
It intends to investigate the following objectives:
i. To examine the role of catchment land-use and seasons in determining river water quality nutrient and dissolved organic carbon concentrations and the effects it has on water quality
ii. To investigate how stream metabolism responds to nutrient and organic matter loading along land use and seasonal gradients
iii. To assess the environmental parameters controlling stream metabolism in tropical streams and their seasonal variation along land-use gradients
iv. To investigate the relationship between stream processes and biological components of the river and their sensitivity to nutrient and organic matter pollution.

Uganda 2022-10-06 9:54:38 2025-10-06 Natural Sciences Non-Clinical Trial Degree Award
Joshua Kiptoo
ID:
SAFETY AND EFFECTIVENESS OF A SELECTED HERBAL MEDICINAL PRODUCT AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN MBARARA CITY, SOUTHWESTERN UGANDA.
REFNo: HS2440ES

To determine the cost-effectiveness of the selected HMP among patients with T2DM in Mbarara City.,To determine the safety of the selected HMP among patients with T2DM in Mbarara City.,To determine the effectiveness of a selected HMP among patients with T2DM in Mbarara City.,To identify the commonly used HMPs among T2DM patients in Mbarara City.,To evaluate the safety and effectiveness of a selected HMP among patients with T2DM in Mbarara City.,
Uganda 2022-10-06 9:53:17 2025-10-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anatoli Muleterwa
ID:
THE ROLE OF POLICING IN COUNTERING URBAN TERRORISM IN KAMPALA METROPOLITAN
REFNo: SS1436ES

General objective
The general objective of the study is to examine the influence of policing in countering urban terrorism in Kampala Metropolitan in order to reduce the incidents of terrorism through improving the working relationship between police and the community.
1.3.2 Specific Objectives
The specific objectives are;
1. To examine the role of police in countering urban terrorism in Kampala Metropolitan
2. To assess the effectiveness of police in identifying and countering urban terrorism in Kampala Metropolitan
3. To explore the role of community in countering urban terrorism in Kampala Metropolitan
4. To examine the relationship between police and community in countering terrorism in Kampala Metropolitan

Uganda 2022-10-05 15:07:23 2025-10-05 Social Science and Humanities Non-Clinical Trial Degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
HIV-1 subtype-specific drug resistance in patients failing dolutegravir-based first-line, second-line or third-line regimens: multiregional study (DTG resist study)”
REFNo: HS2435ES

Main Objective 1.To determine the patterns and spectrum of InSTI DRMs in adults and adolescents with virologic failure on DTG-based ART by ART regimen and HIV-1 subtype. 2. To identify risk factors for virologic failure, InSTI DRMs, and InSTI drug resistance in adolescents and adults on DTG-based ART, including drug, host and health system factors. Specific Objectives 1a) To identify the prevalence of InSTI DRMs at the time of virologic failure. 1b) To compare the prevalence of InSTI DRMs at the time of virologic failure between HIV-1 subtypes and treatment contexts. 2a) To identify risk factors for Virologic Failure 2b) To identify risk factors for Drug Resistance Mutations. 3. To investigate correlations between novel resistance genotypes and phenotypic DTG resistance across HIV-1 subtypes.
Uganda 2022-10-05 15:04:09 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jefferson  Mtongolo Mwaisaka
ID: UNCST-2022-R010784
An impact evaluation study of the Delivering Resilient Enterprises and Market Systems (DREAMS) project targeting refugees and host communities in Bidi Bidi and Rhino Camps, West Nile Uganda
REFNo: SS1445ES

To determine the cost-effectiveness of DREAMS compared to the status quo,To assess if there's any suggestive evidence that outcomes are substantially different for households that participate in both graduation and MSD programs vs households that only participate in graduation programs,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in host communities in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS on livelihoods, social cohesion, and perceived wellbeing among vulnerable households in a refugee camp in Uganda’s West Nile refugee settlements,To determine the impact of DREAMS (poverty graduation + indirect MSD + direct market support) on livelihoods, social cohesion, and perceived wellbeing of vulnerable refugee and host community households in Uganda’s West Nile refugee settlements,
Kenya 2022-10-05 12:26:04 2025-10-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samson Omongot
ID:
Validation of air pollution particulate matter measurements and characterization of the source apportionment using chemical speciation in urban Kampala.
REFNo: NS416ES

ii) To determine sources of pollutants using filter sampler Gravimetric Method in 12 months at Makindye & Kawempe divisions of Kampala district.,Specific objectives for Aim 2 i) To determine chemical composition of pollutants using filter sampler Gravimetric method in 12 months at Makindye & kawempe divisions of Kampala district,Aim 2 General Objective To determine the pollutants’ components in particulate matter (PM) and establish their specific sources using filter sampler gravimetric method in computer-based model Positive Matrix Factorization (PMF),iii) To assess the correlation of PM2.5 measurements between AirQo twin plan tower Monitor and filter sampler Gravimetric method,ii) To determine the correlation of the PM2.5 measurements between the filter sampler Gravimetric method, and the internationally standardized Kampala BAM ,Specific Objectives for Aim 1 i) To determine the correlation of PM2.5 measurements between AirQo twin plan tower monitors and the internationally standardized Kampala BAM ,Aim 1 General Objective To examine the correlation of ambient air pollution PM2.5 measurements between AirQo twin Plan tower Monitor (TPTM), filter sampler Gravimetric method and US Embassy Beta Attenuation Monitor (BAM).,
Uganda 2022-10-05 12:24:41 2025-10-05 Natural Sciences Non-Clinical Trial Non-degree Award
Wilfred Arubaku
ID:
Role of Physiotherapy in Ugandan Neurosurgical Transitional Care
REFNo: HS2369ES

3. To examine the knowledge, attitudes and beliefs of medical providers, rehabilitation providers, patients, and caregivers as to the inclusion of rehabilitation services in discharge practice.,2. To describe the experiences of discharge practice from the perspectives of medical providers, rehabilitation providers, patients, and caregivers.,1. To describe the process steps that are happening during discharge practice for medical providers, rehabilitation providers, patients, and caregivers.,This study aims to examine and understand the involvement of current rehabilitation professionals in discharge practices TBI and SCI patients in acute hospital settings. Results from this study will inform the development of care transition interventions that increase patient access and utilization of rehabilitation services to improve quality of life.,
Uganda 2022-10-05 12:23:17 2025-10-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
Reducing neonatal and maternal mortality by rapid detection of sepsis inresource-limited environments
REFNo: HS2439ES

To assess the perception of health workers on the use of the test for detection of neonatal sepsis in their units. To compare mortality rate within groups of neonates and mothers in whom SAA is detected and those in whom SAA was not detected in a resource-limited environment.
To characterise the clinical presentation and outcome of sepsis in all participants and information on treatment and duration.
To determine the detection of SAA following serial tests and treatment for neonates and mothers suspected to have sepsis.
To describe the proportion of neonates and mothers in whom serum amyloid A (SAA) is detected when expected to have neonatal or maternal sepsis versus available biomarkers.
To identify the technical barriers to implementing of the SAA lateral flow test for the detection of neonatal sepsis, and maternal sepsis.
To understand the non-technical barriers to implementing and adopting the SAA lateral flow test for detection of neonatal sepsis and maternal sepsis.
To evaluate and implement a pre-existing technology for the rapid detection of neonatal and maternal sepsis in a resource-limited environment.
Uganda 2022-10-03 17:37:34 2025-10-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Massy Mutumba
ID: UNCST-2022-R011366
Obuvumu: Improving Health Service Uptake for Survivors of Sexual Violence (SV)
REFNo: HS2364ES

This study seeks to inform the future development of culturally appropriate, feasible, acceptable and effective interventions to increase health service utilization among female survivors of sexual violence. The specific goals of this study are to:
Aim 1: Conduct formative qualitative research to inform a discrete choice experiment (DCE) that will generate systematic information on health service utilization for female survivors of sexual violence (SV) in Uganda;
Aim 2: Using a DCE approach, assess the factors that influence women’s decisions to seek services after experiencing SV among; and
Aim 3: Based on findings from the DCE, apply user-centered design principles to co-design an intervention that addresses barriers and preferences identified in Aims 1 and 2.
Uganda 2022-10-03 17:35:46 2025-10-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Riley-Green
ID:
A VILLAGE-LEVEL POVERTY ALLEVIATION PROGRAM IN UGANDA
REFNo: SS1431ES

Can poverty be alleviated effectively if everyone within a community is eligible for a graduation program, rather than only the poorest? Are the causes of persistent poverty specific to individual households, requiring individualized training and coaching, or are there common elements that can be addressed at the village level within group trainings?,
UK 2022-10-03 10:45:53 2025-10-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
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