Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sheila Balinda Nina
ID: UNCST-2021-R013804
Analysing HIV-1 Reservoir Kinetics, and Host Immune Interactions among non-B subtypes.
REFNo: HS5936ES

General Objective

To understand the dynamics of HIV-1 reservoirs and host immune interactions among non-B subtypes infected participants in Uganda.

Specific objectives:
1. To compare the dimensions of the HIV-1 reservoir among Ugandans, including individuals with high viral loads at the start of ART, and those who have been on ART for varying durations.
2. To detect HIV-1 viral properties associated with latent reservoirs across HIV-subtypes, examining how these patterns may differ and contribute to disparities in reactivation tendencies in Uganda.
3. To detect immune correlates in relation to host characteristics, including HIV-1 specific, B-cells, innate immune cells, CD4 and CD8 cell lineage activation, and exhaustion markers.
4. To develop a supervised machine learning algorithm to predict the HIV-1 latent reservoir behaviours in Uganda.

Uganda 2025-05-23 14:00:42 2028-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Nalikka
ID: UNCST-2024-R016316
Ecological and epidemiological dynamics of viruses in Ugandan bat populations.
REFNo: NS969ES

1. To determine the prevalence, diversity and genetic variation of viruses in different bat species, considering both time and space.
2. To use host density, distribution, and pathogen prevalence to develop models that can be used to forecast spillover risks from bats to other animals, including humans.
3. To investigate the duration of immunity to viruses in bats by sampling individuals across different age groups over time.

Uganda 2025-05-23 13:58:46 2028-05-23 Natural Sciences Non-Clinical Trial Degree Award
Muge Cevik
ID: UNCST-2022-R011548
Improving surveillance and detection of MPXV in Uganda
REFNo: SS3940ES

• To determine seroprevalence of MPXV among people living with HIV in Uganda • To elucidate the risk factors associated with infection.
UK 2025-05-23 13:57:06 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
ochuga patrick olanya
ID: UNCST-2024-R015276
PREVALENCE, AND FACTORS ASSOCIATED WITH CHORIOAMNIONITIS AMONG WOMEN ADMITTED WITH PPROM AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5949ES

To determine the prevalence and factors associated with chorioamnionitis among women admitted with PROM at MRRH
Uganda 2025-05-23 13:54:31 2028-05-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Nina Rugambwa Olivia
ID: UNCST-2019-R000213
SAFEGUARDING MENTAL HEALTH OF CHILDREN WITH PHYSICAL DISABILITIES IN INCLUSIVE PUBLIC PRIMARY SCHOOLS: A CASE OF KAMULI DISTRICT, UGANDA
REFNo: SS3894ES

To explore the coping strategies of children with physical disabilities and their relationship to mental well-being in schools in Kamuli District.,3. To examine mental health safeguarding measures and their implementation in inclusive government primary schools in Kamuli District ,2. To document cultural beliefs and practices that promote mental health and inclusiveness of children with disability at school and in their communities in Kamuli District,1. To determine the mental health status of children with physical disabilities in government-inclusive primary schools in Kamuli district,This study seeks to create awareness about the mental health of children with disabilities and enhance their safety in inclusive government primary schools in Kamuli district.,
Uganda 2025-05-23 13:43:10 2028-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
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