Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Comfort Vandu Danchal
ID: UNCST-2025-R021884
COMPARATIVE GENOMIC ANALYSIS OF CLINICAL AND HOSPITAL-ENVIRONMENT ISOLATES OF P. aeruginosa IN SELECTED HEALTHCARE FACILITIES IN ISHAKA-BUSHENYI MUNICIPALITY, UGANDA.
REFNo: HS7725ES

General objective: To characterize and compare the genomic features, antimicrobial resistance determinants, andvirulence genes of clinical and hospital environmental Pseudomonas aeruginosa isolates inselected healthcare facilities in Bushenyi Ishaka Municipality. Specific objectives: 1. To determine the prevalence of Pseudomonas aeruginosa among clinical and hospitalenvironmental samples in selected healthcare facilities in Bushenyi Ishaka Municipality. 2. To assess and compare the antimicrobial susceptibility profiles of P. aeruginosa isolatesfrom clinical and hospital environmental sources. 3. To identify and characterize antimicrobial resistance genes, virulence factors, and biofilm-associated genes in P. aeruginosa isolates. 4. To analyze and compare the genomic diversity, sequence types, and phylogeneticrelationships of clinical and hospital environmental P. aeruginosa isolates. 5. To compare the genomic profiles of local isolates with global reference strains to determineevolutionary relationships and potential emergence of high-risk clones.
Nigeria 2026-08-07 17:58:06 2029-08-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Charles GALABUZI
ID: UNCST-2026-R024664
UNLOCKING THE WOOD FUEL VALUE CHAIN’S POTENTIAL: CHARCOAL PRODUCTION IN UGANDA
REFNo: SS5356ES

a) To examine the regulatory and other contextual factors, socio-economic characteristics, and demographics of small-scale charcoal producers.
b) To assess charcoal production dynamics, arrangements, and the factors that influence small-scale charcoal production
c) To examine the gendered roles, places and spaces of small-scale charcoal producers with an intersectionality lens.
Uganda 2026-08-07 17:55:22 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Eleku
ID: UNCST-2025-R021209
SMATCH-Soroti: Strengthening Maternal Antenatal Testing and Community Health for Hepatitis B in Soroti
REFNo: HS7460ES

Main objective: Determine the proportion of HBV-infected pregnant women eligible for TDF treatment under centralized (viral load ?10,000 IU/mL) and decentralized (HBsAg+) model. Specific objectives: 1. Assess HBsAg prevalence among pregnant women in Soroti (overall and by site). 2. Assess risk factors for HBsAg positivity. 3. Assess knowledge, and perceptions related to HBV among pregnant women. 4. Evaluate linkage to care and treatment adherence among HBsAg-positive women initiated on TDF; identify barriers to engagement. 5. Characterize maternal HBV DNA dynamics on TDF: reduction in viral load from baseline to delivery. 6. Compare costs of centralized versus decentralized models. 7. Calculate the incremental cost-effectiveness ratio as cost per modelled MTCT case averted (using literature-based transmission rates or maternal viral load as a proxy). 8. Quantify potential overtreatment in the decentralized model: proportion of women treated who would not meet the centralized viral load threshold (<10,000 IU/mL).
Uganda 2026-08-07 17:53:36 2029-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET SEBAANA
ID: UNCST-2026-R025464
TOWARDS A POSTMODERN CSR STRATEGIC COMMUNICATION FRAMEWORK TO BUILD CORPORATE IMAGE: A SINGLE-CASE STUDY OF MTN-UGANDA’S MATERNAL HEALTH PROMOTION CAMPAIGN
REFNo: SS5417ES

General Objective To develop a postmodern CSR strategic communication framework that MTN Uganda can use to build a desired corporate image through its maternal health promotion campaign. Specific Objectives 1. To explore the communication channels used by MTN to build a desired corporate image through its CSR campaign to reduce maternal mortality by improving maternal health. 2. To explore the integration of inclusivity in health promotional campaigns intended to build CI in the context of MTN‘s strategic communication of CSR for improving maternal health. 3. To explore the use of collaboration in health promotion campaigns intended to build CI in the context of MTN‘s strategic communication of CSR for improving maternal health. 4. To explore the use of emergent communication in health promotional campaigns aimed at building CI in the context of MTN‘s strategic CSR communication to improve maternal health. 5. To develop a postmodern CSR strategic communication framework MTN can use to build a desired CI by integrating inclusivity, collaboration, and emergence in health promotional campaigns, for promoting maternal health.
Uganda 2026-08-07 16:48:32 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
Hannington Gumisiriza
ID: UNCST-2026-R023423
Development of a Herbal Anti-Allergy Remedy from Medicinal Plants: Integrating Ethnobotany and Computational Modelling for Value Addition
REFNo: NS1261ES

Specific Objectives:
1. To document medicinal plant species used for allergy-related symptoms in selected districts of Western Uganda, including preparation methods, administration routes, and frequency of citation.
2. To prepare standardized crude extracts and solvent fractions using reproducible extraction protocols from select plant species based on ethnobotanical relevance.
3. To characterize phytochemical constituents of prioritized extracts and fractions using liquid chromatography tandem mass spectrometry, and to establish chemical fingerprints and marker compounds for standardization.
4. To predict anti-allergic activity and molecular targets of identified phytochemicals using structure-based computational modelling approaches, including molecular docking, molecular dynamics simulations, and ADMET profiling.
5. To integrate ethnobotanical frequency data, phytochemical profiles, and computational predictions to prioritize candidate extracts or compounds and generate a chemically standardized herbal lead suitable for staged preclinical validation.

Uganda 2026-08-07 16:44:29 2029-08-07 Natural Sciences Non-Clinical Trial Non-degree Award
Ssozi ArthurRoykin
ID: UNCST-2026-R025602
AI-Assisted Agricultural Extension in Uganda: A Pilot Impact Evaluation
REFNo: A810ES

To estimate the causal impact of AI-based agricultural extension — relative to no extension and human-led extension — on smallholder coffee farmers’ chatbot usage, knowledge of recommended agronomic practices, adoption of those practices, and farm yields.
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To evaluate whether onboarding modality affects engagement with an AI advisory tool, specifically whether video-based onboarding can serve as a scalable, lower-cost substitute for in-person enumerator-led facilitation.
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To assess whether personalized (farm-specific) versus general AI-generated recommendations affect tool take-up and sustained use.
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To test whether a mobile data incentive increases self-directed experimentation with an AI advisory tool.
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To generate operational evidence — on implementation feasibility, effective intermediaries, and support modalities — to inform the design of a full-scale randomized controlled trial (RCT) and UCSATP scale-up decisions.
Uganda 2026-08-07 16:33:35 2029-08-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Chris. Opesen Columbus
ID:
Indigenous Child Care, Parenting and Education (CCPE) Practices that Advance Gender-Equitable and Responsive Early Childhood Care and Education Services in Uganda.
REFNo: SS5535ES

� To explore how caregivers and children exercise agency amid social and global influences.,To assess areas of alignment, tension, and complementarity between indigenous practices and formal CCPE policies and services.,To examine indigenous parenting practices across childhood and adolescence (0�18 years).,To document indigenous childcare practices for children aged 0�8 years and how they shape gender roles.,To explore indigenous child care, parenting, and education practices in Uganda and assess their potential contribution to strengthening gender-equitable and responsive CCPE services.,
Uganda 2026-08-07 16:26:41 2029-08-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOHN BOSCO OKWAJA
ID:
WORKPLACE EQUITY, JOB FIT AND WELL-BEING OF ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS5480ES

i. To examine the influence of workplace equity on the well-being of academic staff in public universities in Uganda.
ii. To assess the influence of job fit on the well-being of academic staff in public universities in Uganda.
iii. To test the moderation of job fit in the influence of workplace equity on the well-being of academic staff in public universities in Uganda.
Uganda 2026-08-07 16:20:01 2029-08-07 Social Science and Humanities Non-Clinical Trial Degree Award
BONIFACE OJOK
ID: UNCST-2023-R006075
Kacel Pi Nippo: Transformative Memory for Mothers and Youth in Northern Uganda
REFNo: SS5672ES

To promote family reunification,to promote intergenerational dialogue through arts based methods,to build youth capacity in documentation of their activities through mentorship and training,to foster community based dialogues towards reconciliation,To conceptualize and understand community led memory practices between mothers and their children born of war,
Uganda 2026-08-05 18:39:34 2029-08-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Humphrey Wanzira
ID:
Diagnostic validity and reliability of a novel prototype combined Malaria and hemoglobin reader: A validation Study conducted in varying Malaria transmission Settings in Uganda
REFNo: HS8263ES

The key objectives shall be to estimate: 1. The sensitivity and specificity of the device prototype 2. And the Positive and Negative Predictive values of the device prototype in detecting malaria parasites and haemoglobin estimation – against microscopy (gold standard), RDTs and PCR 3. Usability, functionality and safety assessment of the device.
Uganda 2026-08-05 18:36:39 2029-08-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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