Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mohammed Lamorde
ID: UNCST-2019-R001293
Clinical Evaluation of the FilmArray Global Fever (GF) Panel
REFNo: HS265ES

To evaluate the clinical sensitivity and specificity of the assays comprising the FilmArray GF Panel when used to test whole blood specimens. It is hypothesized that the FilmArray GF Panel assays will detect clinically relevant levels of the pathogens included in the panel and give no false detections.
Nigeria 2018-12-04 2021-12-04 Medical and Health Sciences Non-degree Award
Gloria Kirungi Kasozi Kasozi
ID:
School-Based Sexual and Reproductive Health Services for Prevention of Adolescent Pregnancy in Hoima District, Uganda: a cluster randomized controlled trial
REFNo: HS247ES

1. To investigate the effect of School Based SRH services on occurrence of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda. 2. To evaluate the effect of School Based SRH services on sexual behavioral change for prevention of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda. 3. To analyze the effect of School Based SRH services on utilization of SRH services among school girls aged 15-19 years in Hoima District, Uganda. 4. To develop a School Based SRH services model for the prevention of adolescent pregnancy among school girls in Uganda
Uganda 2018-11-30 2021-11-30 Medical and Health Sciences Degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
Molecular Epidemiological Surveillance of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum Parasite Population in Uganda
REFNo: HS271ES

(i) To determine prevalence of pfhrp2/3 gene deletions in P. falciparum parasites in Uganda. (ii) To determine the distribution and geographical spread of pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda. (iii) To determine the factors associated with pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda. (iv) To determine diagnostic accuracy of malaria RDTs as compared to blood smear microscopy and PCR in settings where there are pfhrp2/pfhrp3 gene deletions in Uganda. (v) To determine the multiplicity of infections in P. falciparum strains with pfhrp2/ pfhrp3 gene deletions in Uganda. (vi) To determine the genetic diversity of P. falciparum Histidine-Rich Protein-2/3 genes in Parasite populations in Uganda. (vii) To determine the origin and relatedness of pfhrp2/pfhrp3 gene deleted P.falciparum strains in Uganda.
Uganda 2018-11-30 2021-11-30 Medical and Health Sciences Degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
One Dollar Incentive to Improve Tuberculosis Treatment Outcomes in a Programmatic Setting (ODITOPS trial)
REFNo: HS254ES

Primary objectives: 1. To determine the effect of a one dollar incentive on the TB treatment success rate of patients receiving TB treatment in rural hospitals of Uganda and Kenya. 2. To determine the effect of a one dollar incentive on TB loss to follow up rate of patients receiving TB treatment at rural hospitals in Uganda and Kenya Secondary Objectives: 1. To determine the effect of a one dollar incentive on TB death rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya. 2. To evaluate the impact of a one dollar incentive on the TB treatment failure rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya
Uganda 2018-11-13 2021-11-13 Medical and Health Sciences Non-degree Award
Hindum Lanyero
ID:
Monitoring antibacterial use in children under five in rural Communities of northern Uganda.
REFNo: HS235ES

General Objective To investigate antibacterial use among children under five in rural communities of northern Uganda and develop a method that can be used to validate the reported use. Specific objectives 1. To determine antibacterial medicine use patterns as reported by caregivers of children under five who present with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study I). 2. To develop a chromatographic method for simultaneous identification of multiple antibacterial medicines in whole blood and urine spotted on filter paper (Sub-study II). 3. To establish the validity of self-reports in monitoring antibacterial use in children under five who are brought to health facilities with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study III)
Uganda 2018-11-06 2021-11-06 Medical and Health Sciences Degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
Pictures of ageing in Uganda: A pilot study to explore demography, healthy ageing phenotype and self-perception in a community of older people in Uganda
REFNo: SS246ES

Primary objective: To determine the feasibility of combining demographic, phenotypic and artistic methods in understanding the picture of Ageing of community dwelling elderly individuals in Uganda. Secondary objectives: 1) To assess the accuracy of age-reporting among older people (>60 years) living in a Wakiso District community and investigate how the accuracy of age-reporting is linked to health, capabilities, social status and residential circumstances. 2) To pilot test data collection tool for demographic assessment of older people in Uganda (culturally, linguistically, historically appropriate). 3) To pilot test data collection tools for phenotypic assessment of older people in Uganda (health status, frailty, cognition, capabilities, quality of life, co-morbidities including HIV, access to health and other services). 4) To assess feasibility and acceptability of undertaking cognitive testing using electronic tablets in older people living in a Wakiso District community. 5) To assess feasibility and acceptability of engaging older people through visual / performing arts activities. 6) To explore perceptions and attitudes to a community based participatory research in older people building on discussions/ interviews conducted in the context of 1-4 above. 7) To develop an exhibition of artwork by established artists and older people to express their perceptions of older age.
Uganda 2018-11-06 2021-11-06 Social Science and Humanities Non-degree Award
Sarah Baliddawa
ID:
Household members’ role and experiences during MDR-TB patients care at Mbarara Regional Referral Hospital, Uganda
REFNo: HS253ES

General objective:  To explore the roles and experiences of household members during the care of MDR-TB patients attending MRRH Specific objectives:  To explore household members’ definition of MDR-TB  To explore the roles played by household members in care of MDR-TB patients  To explore the experiences of household members during care of MDR-TB patients
Uganda 2018-11-06 2021-11-06 Medical and Health Sciences Degree Award
Nelson TING
ID:
Genetic identity of elephant migrants across a forest-savanna mosaic of protected areas in Western Uganda
REFNo: NS72ES

To generate baseline knowledge of elephant movement, habitat use, and population size in and among the forested protected areas of western Uganda.
USA 2018-10-30 2021-10-30 Natural Sciences Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
Social Support Systems and Community Resource Utilization for Children and Families Affected by HIV/AIDS in Uganda: A Stakeholder Perspectives Study.
REFNo: SS182ES

The overall aim of this research is to examine the social support systems and community resources available to orphaned children and families affected by HIV/AIDS in Southwestern Uganda. Specifically, utilizing a stakeholder perspective, the objectives of this research are: 1) To identify and examine the available social support systems and resources available to children and families affected by HIV; 2) To examine both family-level and community-level facilitators and barriers to access and utilization of community resources; and 3) To identify resource gaps and ways to improve social support systems for children and families affected by HIV. The long-term goal of this proposed research is to inform a developmental research grant application (R21), to test the feasibility, acceptability, and preliminary impact of a social support intervention that can address HIV-related stigma and social isolation, and its impact on the overall social and health wellbeing of orphaned children and their caregivers.
Uganda 2018-10-30 2021-10-30 Social Science and Humanities Degree Award
James Ssuuna
ID:
EFFECT OF HABITAT DISTURBANCE ON POPULATION DYNAMICS AND COMMUNITY STRUCTURE OF RODENTS IN MABIRA CENTRAL FOREST RESERVE, UGANDA
REFNo: NS73ES

1.Assess rodent composition, diversity, and habitat association in undisturbed forest, disturbed forest, and adjacent agricultural/fallow fields in Mabira central forest reserve(MCFR). 2.Determine the influence of habitat structure/disturbance, and seasonal changes on recruitment, and survival of the dominant rodent species in MCFR. 3.Determine the effect of habitat structure/disturbance, and rainfall patterns on the breeding/reproduction patterns of the dominant rodent species in MCFR. 4.Investigate the movement and ranging patterns of the dominant rodent species in MCFR.
Uganda 2018-10-30 2021-10-30 Natural Sciences Degree Award
Sadic Waswa Babyesiza Waswa
ID: UNCST-2019-R000849
PREVALENCE AND DIVERSITY OF HEAMOFLAGELLATES AND FILARIAL WORMS IN RODENTS AND SHREWS INHABITING A DEGRADATION GRADIENT IN MABIRA FOREST RESERVE
REFNo: NS54ES

•Investigate the rodent and shrew species composition and seasonal fluctuations in their population structures along a habitat degradation gradient in MCFR •Identify and describe heamoflagellates and filarial worms in rodents and shrews using their morphological, morphometric and molecular characteristics. •Describe diversity, prevalence, distribution and public health importance of heamoflagellates and filarial worms identified in rodents and shrews of MCFR. •Investigate factors that affect prevalence and distribution of heamoflagellates and filarial worms in rodents and shrews in MCFR. •Investigate the relationship between rodent borne zoonotics prevailing with in adjacent communities Vs heamoflagellates and filarial worms identified in rodents and shrews.
Uganda 2018-10-30 2021-10-30 Natural Sciences Degree Award
Cathryn Townsend Megan
ID:
Human Generosity Among the Ik
REFNo: SS201ES

Based on two empirical studies, conducted in WEIRD (Western, educated, industrialized, rich, and democratic) populations in the USA and in the Netherlands, we hypothesize that perceived fitness interdependence (PFI) is the primary psychological motivator of altruistic or generous actions in human cooperation and that PFI varies according to both the situational and relational contexts of human interactions. This existing empirical evidence needs corroboration in diverse cultural and ecological conditions in order to support the universal value of the hypothesis. The current study will serve as a pilot to determine whether the PFI scales that we have developed would be adaptable to non-WEIRD populations.
UK 2018-10-30 2021-10-30 Social Science and Humanities Non-degree Award
Irene Ayakaka
ID:
A Stakeholder analysis of chronic Lung Disease (CLD) management in Uganda
REFNo: HS232ES

Objectives of the research project: Overall Aim The overall goal of the project which this study aims to inform, is to improve the management of CLD in Uganda. This study seeks to analyze the current CLD policy in Uganda, identify gaps in the policy formulation that may translate to gaps in policy implementation. The aim is to generate evidence that can be used to develop targeted, informed interventions to strengthen CLD programmatic management in this setting. Specifically, the study proposes to achieve this through: 1. Stakeholder analysis and mapping to characterize the actors and networks, their linkages and relative influence and how this affects CLD policy in Uganda. 2. An exploration of the policies for the management and implementation of policies to address CLD in the public health system in Uganda. Stakeholders in this study will be limited to at least one representative from; the Uganda ministry of health; from academia; funders and MOH implementing partners and from civil society to help understand and describe the policy context and to clinical heads from Kampala city based health facilities as representatives to help describe and understand the clinical context.
Uganda 2018-10-30 2021-10-30 Medical and Health Sciences Degree Award
Stephanie Sweet
ID:
Geospatial Analytics for Improved Tax Compliance
REFNo: SS242ES

This research will attempt to analyze tax evasion and estimate the compliance tax gap (difference between potential and actual revenue) through the use of geospatial analytics in Uganda.
USA 2018-10-30 2021-10-30 Social Science and Humanities Degree Award
Shai Andre Divon André
ID:
Community Based Policing: Uganda Case Study (ICT4COP)
REFNo: SS231ES

The Uganda case study provides an insight into African perspectives on COP. The overarching objective of the study is to explore the influence and impact of the Ugandan approach to COP. As such the research in Uganda will focus on: police training, application of policing/community policing and impacts of policing on communities. Parts of the research in Uganda may link to the South Sudan case study including through the impact of Uganda’s approach to policing on South Sudan through police training. The focus on the training component will mainly observe the efforts of the Government of Uganda to assist the crisis in South Sudan through police training, but also on the Ugandan concept of COP and the official structures for the implementation of COP. The focus on application of policing/community policing will explore police-community relations in selected areas in Northern Uganda. This component will also include an element bridging into the South Sudan case study by exploring the dynamics between Ugandan host communities and settled refuges from South Sudan, concentrating on police-community relations and the unique challenges that Ugandan police faces in such contexts. The impacts of policing on communities element will explore how both the police and communities collaborate and how has this collaboration affects a range of human security issues in contexts. To achieve the overarching objective the research will revolves around the following sub-objectives: 1. To analyze COP applied in Northern Uganda 2. To investigate COP applied in a variety of socio-cultural contexts in Northern Uganda 3. To understand COP training provided by Uganda to other African nations
Norway 2018-10-30 2021-10-30 Social Science and Humanities Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
Knowledge, attitudes and perceptions about antibiotic use and resistance among final year medical and pharmacy students- a step toward antimicrobial stewardship
REFNo: HS248ES

Overall Goal of the Project To increase the awareness among the public and various stakeholders (College Principle, curriculum designers, heads of departments, Ministry of Health (MOH)) of the need of antimicrobial stewardship programmes within the curriculum of final year undergraduate medical students with the ultimate aim of antimicrobial stewardship being introduced in the regional hospitals where these students will be posted Specific Objective One To determine the level of competency of final year medical and pharmacy students of the Makerere University and Mount Kenya University Colleges of Health Science to prescribe antibiotics appropriately Specific Objective Two To review and report on the findings of this study to various stakeholders in meetings, conferences within the region and to publish the findings from this study in a peer reviewed journal within the final year of the project
Uganda 2018-10-30 2021-10-30 Medical and Health Sciences Non-degree Award
Violet Korutaro
ID: UNCST-2019-R000618
Baylor-IMPAACT-004: IMPAACT 2009; Protocol titled: Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for Primary HIV Prevention during Pregnancy and Postpartum in Adolescents and Young Women and their Infants Ver
REFNo: HS252ES

a) Primary Objective for PK Component • To determine the concentration of Tenofovir diphosphate (TDF-DP) associated with adequate adherence to FTC/TDF among women observed ingesting daily oral Prep during pregnancy and postpartum. b) Secondary Objective for PK Component • To compare TFV-DP concentrations observed in pregnant and postpartum women c) Primary Objectives for PrEP Comparison Component • To characterise PrEP adherence among HIV- uninfected young women during pregnancy and for twenty-six weeks postpartum, when provided with enhanced adherence support through mobile technology and counselling based on observed drug levels. • To assess the safety of FTC/TDF for PrEP during pregnancy and postpartum by comparing pregnancy outcomes and maternal and infant safety between cohorts. d) Other objectives for PrEP Comparison Component • To identify individual, social and structural barriers and facilitators to PrEP uptake during pregnancy, and to adherence during pregnancy and postpartum. • To compare reported sexual risk behaviours and incidence of sexually transmitted infection, among women who initiate PrEP during pregnancy versus women who decline PrEP. • To compare antiretroviral drug resistance among women and infants who acquires HIV and without exposure to FTC/TDF for PrEP, including whether resistance was transmitted or acquired at time of transmission. • To compare bone density in women who initiated PrEP during pregnancy and women who decline PrEP. e) Exploratory Objective for PrEP Comparison Component • To describe the composition of and changes in the maternal vaginal and gut microbiome and infant gut microbiome according to PrEP exposure.
Uganda 2018-10-30 2021-10-30 Medical and Health Sciences Non-degree Award
Rita Nakalega
ID: UNCST-2019-R000599
Extent of Scale-Up of Human Immunodeficiency Virus Load Testing Services and Linkages to Intensive Adherence Counselling Support among HIV Infected Patients on Anti-Retroviral Therapy in Gomba District Uganda: Secondary Data Analysis.
REFNo: HS255ES

1. To estimate the proportion of PLHIV on ART who had VL tests done from January 2017- December 2017 in Gomba district in Uganda, using descriptive secondary data analysis from a cross-sectional study. 2. To estimate the proportion of PLHIV on ART with unsuppressed VLs from January 2017- December 2017 that were linked for IAC support within a three month period from receipt of VL results in Gomba district in Uganda, using descriptive secondary data analysis from a cross-sectional study. 3. To identify factors associated with the uptake of VL testing and IAC services among those with unsupressed VL using logistic regression analysis in a secondary data analysis from a cross-sectional study. 4. To provide recommendations based on population-based factors likely contributing to IAC services uptake and disseminate new knowledge on VL testing and linkages to IAC support services to district health workers, district leaders and other stakeholders.
Uganda 2018-10-16 2021-10-16 Medical and Health Sciences Degree Award
Alex Nduhura
ID:
PUBLIC PRIVATE PARTNERSHIPS AND THE COMPETITIVENESS OF HYDRO ELECTRICITY ENERGY SUB SECTOR IN UGANDA; CASE OF KARUMA AND BUJAGALI POWER DAM PROJECTS
REFNo: SS193ES

1.5.1 Main Objective The main objective of this study is; To identify the most appropriate public private partnerships models necessary for improving in Uganda hydroelectricity sub sector. 1.5.2 Secondary Objectives To achieve the main objective of this study, secondary objectives are derived. These shall include; a) To examine the legal and regulatory framework for procurement and implementation of PPP’s in Uganda. b) To identify lessons learnt to improve PPPs performance and competitiveness of Uganda’s hydroelectricity sub sector. c) To assess challenges faced in implementing Karuma and Bujagali Power Dams. d) To identify lessons from traditional procurement of power dams that can be used to improve PPP models in the hydroelectricity sub sector e) To establish the key features of PPP’s for improving competitiveness of Uganda’s hydroelectricity energy sub sector.
Uganda 2018-10-16 2021-10-16 Social Science and Humanities Degree Award
Hilary Matfess
ID:
“Gender Norm Change in Contexts of Displacement Through Interviews and Body Map Panels with South Sudanese Women Living in Uganda.”
REFNo: SS239ES

This project aims to supplement the thin literature on women’s experiences during conflict and displacement by leveraging a variety of qualitative research methods, including oral histories, focus group discussions, and through the introduction of a new form of body map storytelling, called “body map panels.” This project is exploratory in nature, marking one of the first steps in gathering data for a dissertation related to gender and conflict in sub-Saharan Africa. The qualitative data gathered in this project will help ground an empirically-driven research agenda for a dissertation, which will be centered on unpacking how conflict dynamics and features of displacement programming and support impact women’s influence and status in post-conflict African states. Through the collection of qualitative data, this project will develop the foundations of a testable hypothesis related to gender, conflict, and social roles. This study aims to document and assess the new roles and responsibilities that women take on in post-conflict and displacement settings and to better design programs serving displaces women. The objectives, as paired with the questions posed by the study are to: Document how different events in the course of conflict and displacement affect women’s roles, and identify some of the most influential, commonly experienced events. Document how gender norms change by identifying salient norms pre-conflict, during conflict, and in displacement contexts. Document women’s reactions to the changes in gender norms at these different contexts.
USA 2018-10-10 2021-10-10 Social Science and Humanities Non-degree Award
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