Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eugene Ruzagira
ID: UNCST-2023-R008282
COVID-19 vaccine effectiveness and variants in Uganda: a test-negative case-control study with genetic sequencing (COVVAR)
REFNo: HS2672ES

Primary Objective To estimate vaccine effectiveness of licensed COVID-19 vaccines against laboratory-confirmed COVID-19 disease. Secondary Objectives 1. To identify circulating SARS-CoV-2 variants in Uganda. 2. To estimate vaccine effectiveness against specific SARS-CoV-2 variants identified by genetic sequencing. 3. To estimate vaccine effectiveness against severe COVID-19 disease. 4. To estimate effectiveness of COVID-19 vaccines against different SARS CoV-2 variants and different COVID-19 disease severities. Exploratory objective 1. To evaluate disease severity due to different circulating SARS CoV-2 variants
Uganda 2023-03-07 10:53:48 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DENIS MUGIZI RWABIITA
ID:
Assessment of meat handler training interventions on hygiene and disease detection in Ugandan slaughterhouses and meat retail outlets
REFNo: A266ES

Use syndromic surveillance to understand the incidence and distribution of important animal and zoonotic disease in Uganda,Assess the impact of mobile training tool on meat inspector knowledge,Assess the impact of nudges on knowledge and practices and food contamination at pork retail,Assess the impact of a targeted meat handler training on the knowledge, attitudes, and practices of meat handlers in Uganda.,
Uganda 2023-03-07 10:50:39 2026-03-07 Agricultural Sciences Non-Clinical Trial Non-degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
Understanding the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda - a quasi experiment
REFNo: HS2689ES

General objective: To understand the effect of varied financial compensation structure for improving the performance, motivation and retention of Community Health Workers in Uganda.

Specific objectives:
1. To determine the optimal performance based financial incentive incentive's structure required for improving the performance, motivation and retention of CHWs.

2. To explore the acceptability and perceptions of potential sustainability of CHWs financial compensation structure to various stakeholders, including the CHWs, and the CHW supervisors at the district and Ministry of Health.

3. To explore the perceived value and impact of financial incentives on CHW's job satisfaction, personal income and livelihood.
UK 2023-03-07 10:40:31 2026-03-07 Medical and Health Sciences Clinical Trial Non-degree Award
Stephen  Ojiambo Wandera
ID: UNCST-2021-R012147
Assessing Dementia and Frailty among Older Persons in selected rural districts in Eastern Uganda
REFNo: HS2693ES

Therefore, the aim this study is to determine the prevalence of frailty and dementia among older persons in rural Uganda. Specific aims of the study include:
Aim 1: To estimate the prevalence and factors associated with dementia among older persons in Uganda.
Aim 2: To estimate the prevalence and factors associated with frailty among older persons in Uganda.
Aim 3: To explore the experiences and perceptions of caregivers of older persons with dementia in Uganda.
In this study, we refer to point prevalence only.

Uganda 2023-03-07 10:36:00 2026-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SONNY ASIMO
ID:
RISK FACTORS FOR FLUOROQUINOLONE RESISTANCE AMONG PATIENTS WITH SECOND LINE-DRUG RESISTANT TUBERCULOSIS EVALUATED AT THE UGANDA NATIONAL TUBERCULOSIS LABORATORY RefNo: CLARKE-2022-546
REFNo: HS2709ES

iii. To determine clinical factors associated with fluoroquinolone resistance in patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,ii. To characterize fluoroquinolone-resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,i. To determine the individual characteristics associated with fluoroquinolone resistance among patients with second-line drug resistant TB evaluated at the Uganda National Tuberculosis Reference Laboratory. ,The study will determine the risk factors for fluoroquinolone resistance among patients with second-line drug resistant tuberculosis among previously evaluated samples in Uganda. ,
Uganda 2023-03-07 10:25:46 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Perpetra Akite
ID: UNCST-2023-R008264
Systematic study of insect fauna in selected sites in Uganda (Insect Systematic Project)
REFNo: NS494ES

To sample a broad geographic area, including some of the never-collected or poorly-collected sites to yield new species that will be valuable to the insect systematic community and inform their conservation management
Uganda 2023-03-07 10:24:40 2026-03-07 Natural Sciences Non-Clinical Trial Non-degree Award
JOAN TUSABE
ID: UNCST-2021-R013942
FACTORS INFLUENCING UPTAKE AND ADHERENCE TO PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) CARE AMONG REFUGEE HIV POSITIVE PREGNANT MOTHERS AGED 18 YEAS AND ABOVE IN KYANGWALI REFUGEE CAMP
REFNo: HS2711ES

1. To determine the level of uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

2. To determine factors associated with uptake and adherence to prevention of mother to child transmission (PMTCT) services among refugee pregnant mothers aged 18 years and above in Kyangwali refugee camp

3. To explore barriers and facilitators for uptake and adherence to prevention of mother to child transmission (PMTCT) services among HIV positive pregnant mothers aged 18 years and above in Kyangwali refugee camp


4. To determine strategies that can be put in place to improve uptake and adherence to prevention of mother to child transmission (PMTCT) among refugee HIV positive pregnant mothers in Kyangwali refugee camp?

Uganda 2023-03-07 10:23:51 2026-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Samson Udho
ID: UNCST-2021-R013728
Respectful maternity care in childbirth among adolescents aged 14 to 19 years in rural northern Uganda: a mixed-method study
REFNo: HS2727ES

The objectives are to: 1. Determine the prevalence of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 2. Determine the predictors of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 3. Explore the experiences of D&A of adolescents by SBA during childbirth in public health facilities in rural northern Uganda. 4. Explore the drivers of D&A of adolescents aged by SBA during childbirth in public health facilities in rural northern Uganda.
Uganda 2023-03-02 16:34:50 2026-03-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Fred Kaggwa
ID: UNCST-2022-R008842
Evaluating Mbarara University of Science and Technology (MUST) Internal Quality Assurance Mechanisms (IQAMs) on her Quality
REFNo: SS1629ES

General Objective
To evaluate MUST’s IQAMs on her quality using the IUCEA Model
Specific Objectives
1.To evaluate MUST’s IQAMs on the quality of Teaching and Learning
2.To examine MUST’s IQAMs on the quality of Research and Innovations
3.To assess MUST’s IQAMs on the quality of Community outreach

Uganda 2023-03-02 16:23:10 2026-03-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
ESTABLISHMENT AND EVALUATION OF CAPRI CELLS IN UGANDA FOR ADOPTIVE CELL THERAPY
REFNo: HS2684ES

1. Evaluate the reproducibility of Cascade Primed Cells with Apheretic collected Autologous PBMCs in Uganda
2. Test the effect of the reproduced CAPRI cells on Lung and Cervical cancer cells in vitro

Uganda 2023-03-02 15:39:34 2026-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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