Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
International classification, cancer and care: Accounting for the diagnostic potential of low- and middle-income countries
REFNo: SS3561ES

NOTES: The overall project is guided by three research questions, given here with their related objectives. Specific objectives for research activities in Uganda are also described. RESEARCH OBJECTIVE 1: What are the “on-the-ground realities” of brain tumour diagnosis and care in Sub-Saharan Africa and how does diagnostic practice in brain tumours differ across the region? OBJECTIVE 1: To develop three detailed empirical case studies of diagnostic work and brain tumour care in Uganda, Nigeria and South Africa that are embedded in understandings of care23, national policy, socio-technical infrastructures, and international classification. OBJECTIVE 2: To compare empirical case studies to develop rich understandings of how practitioners in Sub-Saharan Africa use, refuse, or adapt WHO classifications, or mobilise to establish their own terms of reference. OBJECTIVE 3: To generate critical perspectives on diagnostic value, where diagnosis might not be assumed an essential condition of good care. RESEARCH QUESTION 2: How are the diagnostic contexts of LMICs considered by experts writing international cancer classifications? OBJECTIVE 4: To examine how international cancer classifiers understand diagnostic approaches and infrastructures in LMICs. OBJECTIVE 5: To examine the individual values and institutional principles that guide how classifiers consider these approaches in their decision-making about cancer classification. RESEARCH OBJECTIVE 3: How are local medical practitioners, cancer advocates, and international organisations mobilising in a regional network to improve brain tumour outcomes across Sub-Saharan Africa? OBJECTIVE 6: To explore how local medical practitioners, advocates, and international organisations in Sub-Saharan Africa are collaborating in a new professional network, Society for Neuro-Oncology Sub-Saharan Africa (SNOSSA), to improve brain tumour diagnosis and care across Sub-Saharan Africa. OBJECTIVE 7: To examine how members understand unity and diversity among Sub-Saharan African countries, and establish common aspirations and strategies concerning diagnosis and classification. OBJECTIVE 8: To explore how members understand their work on a disease which is considered rare, yet its true incidence unknown, and which is de-prioritised in national and international funding. The specific research objective for research conducted in Uganda is to develop a thorough ethnographic understanding of how brain tumour diagnosis happens in practice; how diagnostic work relates to local sociotechnical infrastructure, national policy, and international classification; and how diagnosis relates to care and treatment decision-making.
Uganda 2025-03-14 18:29:40 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
ssonko jackson
ID: UNCST-2022-R009683
SOCIAL SECURITY POLICY IMPLEMENTATION AND CLIENTS' SATISFACTION: A CASE OF NATIONAL SOCIAL SECURITY FUND BENEFICIARIES IN UGANDA .
REFNo: SS2326ES

To investigate the contribution of the Social Security Policy Implementation on NSSF Clients’ Satisfaction in Uganda,To assess the influence of Legal framework for social security on NSSF clients’ satisfaction in Uganda.,To analyze the congruence between of Social Security Policy Implementation andLegal framework for social security with particular reference to NSSF in Uganda,To investigate the contribution of the Social security policy to NSSF clients’ satisfaction. The donation is regarded as mediating the Legal Framework for Community Safety with a particular focus on Kampala and the surrounding areas of Uganda.,
Uganda 2025-03-14 18:26:08 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
GWOKYALYA EDITH BAAGALA
ID: UNCST-2023-R005596
Academic staff workload and Quality management in private chartered universities in Uganda
REFNo: SS3509ES

i. To examine the effect of the academic staff workload on total quality management in Private chartered universities in Uganda.
ii. To evaluate the effect of academic staff workload on faculty development programs in private chartered universities in Uganda.
iii. To examine the effect of faculty development programs on total quality management in Private chartered universities in Uganda.
iv. To assess the mediating effect of faculty development programs in the relationship between academic staff workload and total quality management in Private chartered universities in Uganda

Uganda 2025-03-14 18:24:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Paulous Serugo
ID: UNCST-2023-R005541
EFFECT OF BIOTECHNOLOGY-GENERATED CROPS ON SOCIALAND ECONOMIC JUSTICE OF SMALLHOLDER FARMERS IN CENTRAL UGANDA
REFNo: SS2560ES

To evaluate the benefits and costs of biotechnology-generated crops on the social justice of smallholder farmers.,To investigate the effect of biotechnology-generated crops on improved food availability for smalljholder farmers,To analyse the effect of biotechnology-genrated crops on the growing and utilization of indigenous crops,To assess the adoption process of biotechnology generated crops among smallholder farmers in cnetral Uganda,Investigate the effect of biotechnology-genrated crops on social and economic justice of smallholder farmers in central Uganda,
Uganda 2025-03-14 18:22:43 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Brenda Ainomugisha
ID: UNCST-2021-R013462
EFFECT OF POINT-OF-CARE CONTRACEPTIVE PROVISION ON MODERN METHODS UPTAKE AMONG WOMEN DELIVERING BY CESAREAN SECTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS4718ES

MAIN OBJECTIVE
To describe patterns of immediate postpartum contraceptive uptake, evaluate the effect of point-of-care
provision on uptake, and identify factors influencing uptake among women delivering by cesarean
section at Mbarara Regional Referral Hospital.

SPECIFIC OBJECTIVES
1. To determine the prevalence of immediate postpartum modern contraception uptake among women
delivering by cesarean section at Mbarara Regional Referral Hospital
2. To determine the factors associated with immediate postpartum modern contraception uptake among
women delivering by cesarean section at Mbarara Regional Referral Hospital
3. To evaluate the effect of point-of-care contraceptive provision intervention on immediate postpartum
modern contraceptive uptake among women delivering by cesarean section at Mbarara Regional
Referral Hospital
4. To explore the barriers and facilitators of point-of-care contraceptive provision on immediate
postpartum modern contraceptive uptake among women delivering by cesarean section at Mbarara
Regional Referral Hospital
5. To describe postpartum modern contraceptive uptake among women who experienced the point of care
provision of contraceptive methods up to one year of follow-up
Uganda 2025-03-14 18:18:20 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Alex Muheesi Gerald
ID: UNCST-2024-R002585
PUBLIC PROCUREMENT MANAGEMENT PRACTICES AND SERVICE DELIVERY
REFNo: SS3520ES

General objective
To examine the effect of procurement management practices on service delivery by Ugandan Cities
Specific objectives
i. To examine the effect of procurement planning on service delivery
ii. To assess the effect of transparency and accountability on service delivery
iii. To evaluate the effect of competitive bidding on service delivery
iv. To examine the effect of contract management on service delivery
v. To assess the role of leadership and politics on service delivery

Uganda 2025-03-14 18:15:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Musa Sekamatte
ID: UNCST-2024-R016555
Understanding Multisectoral Collaboration for Strengthening Antimicrobial Resistance Interventions in Uganda.
REFNo: HS5641ES

1. To examine how MSC for strengthening AMR interventions occurs
2. To determine the barriers for facilitators for strengthening MSC of AMR interventions
3. To describe features of a desirable MSC model for strengthening AMR interventions

Uganda 2025-03-14 18:11:39 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Jessica Lambert Elisabeth
ID: UNCST-2024-R003524
Tracing the Pathways
REFNo: SS3347ES

 To identify barriers and enablers to successful program implementation, To evaluate the cost-effectiveness of the interventions, To compare the outcomes of different interventions and identify key factors contributing to well-being and self-reliance., To evaluate the current mental health status and self-reliance of former beneficiaries of TPO_Uganda’s programming,
USA 2025-03-14 18:07:03 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Innocent kemigisha
ID: UNCST-2024-R003156
EVALUATING THE EFFICACY OF CONTINUOUS PROFESSIONAL DEVELOPMENT PROGRAMMES FOR TRAINERS IN TECHNICAL AND VOCATIONAL EDUCATION AND TRAINING IN UGANDA
REFNo: SIR423ES

iv. Determine professional development needs of TVET trainers in Uganda.,iii. Ascertain the challenges that were met when implementing these programs.,ii. Determine the impact of CPD on TVET trainers in Uganda.,i. Find out the features of the CPD programs that have been conducted for TVET trainers in Uganda.,The research will analyze continuous professional development (CPD) programmes for TVET trainers in Uganda to determine their effectiveness,
Uganda 2025-03-14 18:05:40 2028-03-14 Engineering and Technology Non-Clinical Trial Degree Award
Richard MIGISHA
ID: UNCST-2024-R002154
Enhancing Zoonotic One Health Engagement and Communication (ZOHEC) and Non-communicable diseases (NCDs) intervention in selected districts of Southwestern Uganda
REFNo: HS5420ES

To enhance the prevention, detection, and control of zoonotic diseases, diabetes and hypertension by strengthening risk communication, community engagement, surveillance systems, and the capacity of health workers, while fostering collaboration across human, animal, and environmental health sectors,
Uganda 2025-03-14 18:02:18 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Steven Bulega Elijah
ID: UNCST-2024-R003520
FACTORS ASSOCIATED WITH IMMEDIATE ADVERSE MATERNAL AND NEONATAL OUTCOMES OF OBSTRUCTED LABOR AT KAYUNGA REGIONAL REFERRAL HOSPITAL IN UGANDA
REFNo: HS5564ES

1. To identify the prevalence of obstructed labor at KRRH among women that delivered there from January to December 2023
2. To assess the factors associated with the immediate adverse maternal and neonatal outcomes of obstructed labor at KRRH among women that delivered there from January 2023 to December 2023
3. To explore the immediate adverse maternal and neonatal outcomes of obstructed labor at KRRH among women that delivered there from January 2023 to December 2023
Uganda 2025-03-14 18:00:07 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lynn Atuyambe Atuyambe
ID: UNCST-2021-R012602
Exploring the facilitators and barriers of coverage, access, and use of HPV vaccination services among girls aged 10-14 years in Uganda
REFNo: SS3473ES

4. Determine the overall national performance of HPV vaccination in Uganda,3. Describe Uganda’s overall context of cervical cancer and HPV vaccination in cancer prevention and adolescent health,2. To document the challenges facing the least performing 12 districts, the interventions applied through the World Bank Group grant-funded activities,1. To explore the facilitators and barriers of coverage, access, and use of HPV first and second dose (full dose vaccination) services among girls aged 10-14 years in Uganda ,
Uganda 2025-03-14 17:53:23 2028-03-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
Impact of an outreach program on reduction of pediatric surgical disease in a refugee population
REFNo: HS5568ES

Aim 1: Evaluate the impact of an outreach program on reduction of pediatric surgical disease and averted disability (a) in comparison to a historical cohort (b). Aim 2: Assess acquisition of knowledge and behavior change of refugee settlement healthcare providers in identifying and referring pediatric patients with surgically treatable disease.
Uganda 2025-03-14 17:50:38 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wilber Sabiiti
ID: UNCST-2024-R016293
Field clinical evaluation of the NG-Test Point of Care lateral flow device (LFD) for monkeypox diagnosis in Uganda
REFNo: HS5602ES

To evaluate detection performance and clinical agreement of Rapid Point of Care (POC) antigen assay for diagnosis of mpox among clinically suspected patients in healthcare facilities in Kampala, Wakiso, Mukono, and Nakasongola districts in Uganda.

Specific objective 1
To determine the diagnostic sensitivity, specificity, & predictive values of the Rapid NG-Test antigen
assay in comparison to PCR and sequencing among patients with mpox
Specific objective 2
To identify MPXV clade (s) circulating among patients with mpox through virologic metagenomic
sequencing

Uganda 2025-03-14 17:48:15 2028-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOLLY KAKKAYI NYESIGIRE
ID: UNCST-2024-R004296
TALENT MANAGEMENT PRACTICES AND EMPLOYEE PERFORMANCE IN SELECTED PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS3682ES

The objectives of this study are:
1. To examine the influence of talent attractiveness on employees performance in Public Universities;
2. To investigate the effect of talent motivation on employees performance in Public Universities;
3. To explore the effect of talent development on the performance of employees in Public Universities;
4. To establish the relationship between talent retention and employees performance in Public Universities.
5. To examine the moderation effect of employee commitment on the relationship between talent management practices and employee performance.

Uganda 2025-03-14 17:45:15 2028-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Victor Musiime
ID: UNCST-2021-R013794
A global phase 3, randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in adolescents and adults with sickle cell disease
REFNo: HS5637ES

1. To demonstrate superiority of
treatment with etavopivat
versus placebo in adolescents
and adults with SCD.
2. To evaluate clinical efficacy
measures of etavopivat treatment
versus placebo in adolescents
and adults with SCD
3. To assess clinically meaningful
improvement in fatigue and
functional exercise capacity
and QOL measures of
adolescents and adults with
SCD taking etavopivat
treatment compared to placebo
Uganda 2025-03-14 17:26:26 2028-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
UMI BUNU OMAR
ID: UNCST-2024-R002604
ASSESSMENT OF THE IMPACT OF SUBSTANCE OF ABUSE AMONG YOUTH IN BUSHENYI DISTRICT, WESTERN UGANDA.
REFNo: HS5415ES

i) Determining the prevalence and associated factors of substance of abuse among youth in Bushenyi District, Western Uganda.
ii) Assess the patterns of abused substances among the youth in Bushenyi District, Western Uganda.
iii) Determine the impact of substance of abuse on the youth in Bushenyi District, Western Uganda.
iv) Evaluate interventions implemented against abused substances among youth in Bushenyi District, Western Uganda

Kenya 2025-03-14 16:57:28 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Francis Okello
ID: UNCST-2019-R000024
Understanding the economic impact of universal household hand hygiene in children under five in Uganda
REFNo: HS3181ES

To explore the health inequality impact of providing alcohol-based hand rub to mothers enrolled in the Babygel trial.,To determine the association between catastrophic health expenditure and under-five mortality in Uganda.,To estimate the extent to which handwashing with soap offers financial risk protection from out-of-pocket expenditure for treatment of diarrheal disease in children under five in Uganda. ,The main objective is to assess the benefits of household hand hygiene practices in terms of financial risk protection and reduction of health inequality. Furthermore, we will explore the association between under-five mortality and catastrophic health expenditure.,
Uganda 2025-03-14 16:38:36 2028-03-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Nagawa
ID: UNCST-2022-R009705
EARLY NUTRITIONAL INTERVENTION FOR NUTRITIONALLY AT-RISK INFANTS UNDER 6 MONTHS OF AGE TO REDUCE MALNUTRITION IN THE FIRST YEAR OF LIFE
REFNo: HS3503ES

5. To assess the maternal and health worker perceptions on the integrated intervention package.,4. To assess the effect of an early integrated family intervention program for LBW and undernourished children u6m on growth in the first year of life.,3. To understand the barriers and facilitators to the integration of maternal mental health care and community-based management of malnutrition in infants u6m of age.,2. To assess the prevalence of maternal mental health among caregivers of u6m infants.,1. To determine the factors associated with malnutrition among infants u6m of age and challenges caregivers of LBW and undernourished infants face. ,2. To assess the prevalence of malnutrition among infants u6m and their associations, To assess the effect of an early integrated nutrition intervention for nutritionally at-risk infants u6m of age in reducing malnutrition in the first year of life. ,
Uganda 2025-03-14 16:37:34 2028-03-14 Medical and Health Sciences Clinical Trial Degree Award
Joseph Mukasa
ID: UNCST-2024-R015786
Youth with Disabilities in Local Government Development Implementation: Exploring the Inclusivity of Mainstream Livelihoods Programmes in South-Western Uganda
REFNo: SS3674ES

The objectives of the research project are to:
1.Conduct a scoping review on the inclusion of youth with disabilities in mainstream livelihood programmes.
2.Determine the participation of youth with disabilities in the implementation of mainstream livelihood programmes.
3.Investigate the factors influencing the inclusion of youth with disabilities in mainstream livelihood programmes.
4.Explore the role played by Organisations of Persons with Disabilities in promoting the inclusion of youth with disabilities in mainstream livelihood programmes.
5.Propose a framework for practicing disability inclusive youth livelihoods development in local government.

Uganda 2025-03-10 18:06:19 2028-03-10 Social Science and Humanities Non-Clinical Trial Degree Award
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