Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Anna Nordén
ID:
Social Acceptance of a green Transition in East Africa
REFNo: SS1666ES

Civil servants and policy makers working with environmental related policies and policy instruments in East Africa.,Enhancing Evironmental related policies and policy instruments in East Africa.,
 Sweden 2023-05-18 15:05:28 2026-05-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannington Businge
ID: UNCST-2022-R009477
 Board Characteristics, Strategic Orientation and performance of Insurance Companies in Uganda UCUREC-2022-392
REFNo: SS1546ES

To examine the influence of strategic orientation on the relationship between board characteristics and performance of Insurance companies in Uganda.,To determine the influence of board characteristics on performance of Insurance companies in Uganda.,To establish the board practices of Insurance companies in Uganda.,The overall objective of the study will be to determine the influence of strategic orientation on the relationship between board characteristics, and performance of Insurance Companies in Uganda. ,
 Uganda 2023-05-18 15:00:59 2026-05-18 Social Science and Humanities Non-Clinical Trial Degree Award
Michael Mukiibi
ID:
Effectiveness of a Smartphone Application on the Accessibility to Information on Maternal, Newborn, and Child Health Care in Slum Settlements in Uganda
REFNo: HS2818ES

i To investigate whether, and how, a smartphone-based job aid used by CHWs improves women’s uptake of facility-based delivery and other maternal health services in Uganda. ii To establish the accessibility of infant and maternal healthcare information by New born and Child health care uptake of facility-based delivery and other maternal health services in Uganda iii To develop a mobile smartphone application to address the accessibility to the information on Maternal, Newborn, And Child Health Care in Slum Settlements in Uganda iv To pilot-test the application in the study area
 Uganda 2023-05-11 15:03:31 2026-05-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Maxensia owor
ID: UNCST-2021-R014003
 Metabolic Impact of Dolutegravir based ART in Postpartum Women Living with HIV and their Infants” (MI-DART study)
REFNo: HS2809ES

Aim 1: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and weight in postpartum women.
Aim 2: To determine the impact of maternal HIV and DTG-ART on i) energy intake and expenditure, ii) metabolic profile and iii) body composition and growth of their HEU infants.

Uganda 2023-05-11 15:01:13 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Russell Michael
ID:
Fire and Climate in the Rwenzori Mountain National Park
REFNo: NS531ES

To develop a long-term record of fire in high-elevation areas of the Rwenzori Mountain National Park. With this record, we will investigate the relationship between fire and climate change through time. Our ultimate objective is to determine whether changes in air temperature cause changes in fire frequency through time. This will allow us to better predict changes in fire regime in the future.
 USA 2023-05-11 15:00:00 2026-05-11 Natural Sciences Non-Clinical Trial Non-degree Award
George Kipaalu Bogere
ID:
Internal Audit Function and Public Funds Management in Uganda. A case of selected Local Governments in Busoga sub Region.
REFNo: SS1708ES

1. To establish the relationship of Internal Audit function and Internal Control System Evaluation in Uganda. A case of selected Local Governments of Busoga.
2. To determine the effect of Internal Control System Evaluation on Auditor Independency and Integrity in Uganda. A case of selected Local Governments of Busoga.
3. To evaluate the Correlation between Audit independency and integrity and public funds management in Uganda. A case of selected Local Governments of Busoga.
4. To establish the association between internal Audit function and public funds management in Uganda. A case of selected Local Governments of Busoga.

 Uganda 2023-05-11 14:59:17 2026-05-11 Social Science and Humanities Non-Clinical Trial Degree Award
MARBLE NASASIRA
ID: UNCST-2021-R012753
 INCIDENCE AND PREDICTORS OF QTC PROLONGATION AMONG DRUG RESISTANT TUBERCULOSIS PATIENTS RECEIVING BEDAQUILINE BASED REGIMEN IN UGANDA.
REFNo: HS2802ES

To develop and validate a clinical risk score To estimate the risk of QTc prolongation after initiation of BDQ-containing regimens among DR-TB patients,To determine the predictors of QTc prolongation among patients receiving drug resistant tuberculosis treatment in Uganda,To assess the incidence of QTc prolongation among patients receiving drug resistant tuberculosis treatment in Uganda.,To determine the incidence, factors associated with QTc prolongation, develop and validate risk score among patients receiving BDQ based regimen. ,
 Uganda 2023-05-11 14:57:53 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Phase B SAPPHIRE
REFNo: HS2784ES

Reduce HIV incidence using innovative strategies for HIV prevention and
treatment to simultaneously reach persistent driver populations.

 Uganda 2023-05-11 14:55:58 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to monitor Grey Crowned Cranes in Uganda
REFNo: NS518ES

1. Understand movement, long-term survival and landscape use of the Grey Crowned Cranes.
2. Provide data on Grey Crowned Crane populations and their distribution in Uganda
3. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
4. Identify areas where the potential exists for crane conservation interventions

Uganda 2023-05-11 14:53:15 2026-05-11 Natural Sciences Non-Clinical Trial Non-degree Award
Ali Ssetaala
ID: UNCST-2021-R011817
 CHILI- Adaptation
REFNo: HS2758ES

To support development of a new screening test for Cervical Cancer detecting high risk HPV DNA phenotypes and cancer proteins biomarkers in low-income countries.

Specific Objectives
1. To collect and analyze self-samples
2. To identify high risk HPV DNA in the self-samples
3. To link the levels of proteins measured in the self-samples with the cervical cancer lessions detected by papsmear and VIA.
4. To evaluate the effect of confounding factors on the cervical cancer protein levels in the self-samples

2.To understand user’s perspectives regarding (self-) sampling

 Uganda 2023-05-11 14:52:00 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon Kigozi Peter
ID: UNCST-2022-R009813
 Studying Incidence of Malaria from Routine Health Facility Reporting to Assess Impact of Targeted Control Interventions: Transforming Surveillance for Malaria Control
REFNo: HS2783ES

4. Investigate the level of residual burden of malaria missed by routine surveillance using randomised surveys.,3. Estimate the impact of targeted control intervention on incidence of malaria within health-facility-catchments.,2. Describe population spatial access to routinely reporting health facilities and estimate health facility catchments.,1. Evaluate the quality of routine HMIS data generated through the national surveillance system (DHIS-2) against facility register records.,To investigate the effectiveness of HMIS-based incidence in assessing the impact of targeted control interventions on malaria burden, through the following objectives.,
 Uganda 2023-05-11 14:50:40 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur  Mpimbaza
ID: UNCST-2022-R008866
 Malaria rapid diagnostic test (RDT) capture and reporting assessment (MaCRA): Uganda protocol
REFNo: HS2747ES

Primary
1. Measure agreement between HCW and panel RDT results in Uganda.
Secondary
2. Measure the association between key characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics and type of agreement/disagreement between the HCW and panel RDT results.
3. Understand how characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology, and patient demographics affect the ability of HCWs to accurately implement, interpret, use, record and report RDT results.
4. Assess the fidelity of data entry from health facility registers to the health management information system (HMIS).
5. Determine the degree of over- and under- treatment for malaria and associations with characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics.
6. Determine whether there is an observer impact of the study on monthly test positivity rates (TPRs).
7. Develop a database of photos of results from various RDT brands that can be used to train an artificial intelligence application to automate the interpretation and reporting of RDTs.
8. Classify common unusual RDT results that appear in RDT photos and assess patterns of errors to guide NMP and PMI on issues related to RDT administration and case management practices.
9. Calculate the accuracy of HealthPulse (Audere, Seattle, WA), a smartphone-based application that uses artificial intelligence to interpret RDT results, compared to the panel RDT results after training on a random selection of RDT photographs.
10. Compare agreement of RDT results read at one week and one month after administration with the initial read to determine the durability of RDT results over time.

 Uganda 2023-05-11 14:45:16 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominik Biesalski
ID:
The Drivers, Effects and Measurement of Time Use Among the Urban Poor: Evidence from Uganda
REFNo: SS1674ES

Get insights into the time use patterns of urban workers and understand their effects on productivity and well-being.
 Germany 2023-05-11 14:41:00 2026-05-11 Social Science and Humanities Clinical Trial Degree Award
Anthony  Batte
ID: UNCST-2022-R011127
 Malaria Associated Pathogenesis of Chronic Kidney Disease (MAP-CKD) Study
REFNo: HS2794ES

To define the impact of AKI and persistent kidney disease on morbidity, mortality, and health-related quality of life. ,To define host pathways associated with maladaptive kidney repair following severe malaria associated AKI. To determine risk factors for short-term and long-term kidney disease following severe malaria,
 Uganda 2023-05-11 14:33:58 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ruth Obaikol
ID: UNCST-2021-R012513
 FACILITY-BASED MENTAL HEALTH CARE FOR VICTIMS OF GENDER-BASED VIOLENCE: CURRENT PRACTICE, DEVELOPMENT AND TESTING OF AN ICT MANAGEMENT SYSTEM
REFNo: HS2669ES

1. To establish the type and nature of psychological care offered to GBV victims reporting to hospitals in Kampala describe the current practice of mental health care for post-violence victims and test a novae approach in a Hospital setting in Ugandan. ,To determine the user satisfaction of patients and caregivers with TSM,To assess the feasibility and the effectiveness of a Hospital-Based Technology supported mental health care intervention (TSM) in management of mental Health effects of violence among adult women. To determine the experiences of healthcare providers in integrating psychological care in the case management of GBV victims who are receive care in Kampala.
 Uganda 2023-05-11 14:18:19 2026-05-11 Medical and Health Sciences Non-Clinical Trial Degree Award
John Bosco Alege
ID: UNCST-2020-R014831
 Effectiveness of Integrated Viral Hepatitis B, C, and HIV Care Model to Optimize Screening Uptake among mothers and newborns at health facilities in West Nile Region, Uganda
REFNo: HS2706ES

The overall aim of this study is to evaluate the effectiveness of integrated viral hepatitis B, and C Care Model to Optimize screening among mothers and newborns at health facilities in West Nile region, Uganda.
Uganda 2023-05-11 13:53:29 2026-05-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Isabelle Clark Rae
ID: UNCST-2022-R010329
 Social development of infant and juvenile chimpanzees in two communities following permanent fission at Ngogo, Kibale National Park, Uganda
REFNo: NS413ES

To determine the demographic, social and individual-level factors shaping social development in two adjacent communities of different size and composition following a rare permanent fission.
 USA 2023-05-11 13:52:27 2026-05-11 Natural Sciences Non-Clinical Trial Degree Award
Joshua Musinguzi Bazaale
ID:
HIV Case Surveillance of Newly Diagnosed People Living with HIV at the time of diagnosis in Uganda
REFNo: HS2171ES

1)Identify and describe geographic locations associated with newly-diagnosed cases including recent infections to inform geographic prioritization of HIV prevention interventions;
2)Monitor and describe epidemiological trends in newly-diagnosed HIV cases by demographics, behavior, mode of transmission, and recency of HIV infection to inform prioritization of HIV prevention interventions to specific populations;
3)Monitor and describe trends of clinical status (WHO Stage, initial CD4, other opportunistic infections) at the time of diagnosis; and
4)Monitor and describe trends in linkage to services (e.g., same-day ART) at the time of diagnosis.

Uganda 2023-05-11 13:50:47 2026-05-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sarah Juster
ID: UNCST-2023-R007855
 Tree-Based Interventions in the Imvepi Refugee Settlement in Uganda
REFNo: NS544ES

Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from staff of UNCHR, OPM through additional interviews and attending settlement Refugee Welfare Council and Local Council meetings,Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from staff of UNCHR, OPM through additional interviews and attending settlement Environment and Livelihood sector meetings,Gain additional perspective on the role of NGO Tree-Based Interventions in Imvepi from Refugee Welfare Council and Local Council members,Gain overarching context for Tree-Based Intervention implementation in Imvepi ,Specifically code transcripts to synthesize themes related to NGO staff perspectives on the challenges of Tree-Based Intervention implementation and recommended programming adjustments,Employ content-analysis coding and axial coding of transcripts of staff interviews and organizational documents for qualitative synthesis of organizational activities and characteristics,Use a comparative table to specifically assess patterns in terms of overlap between Tree-Based Intervention activities and characteristics of the promoting NGO,Synthesize the characteristics and activities of four NGOs promoting Tree-Based Interventions in Imvepi,Compare the environmental characteristics of Tree-Based Interventions across four NGOs in Imvepi, including species choice and integration of TBI activities with local ecological features,Compare social dimensions of Tree-Based Interventions across four NGOs in Imvepi, including the integration of local perspectives and staff, focus on socioeconomic benefits of trees to participants, and inclusion of women as staff and program participants,Compare the nature, source, and duration of Tree-Based Intervention funding across four NGOs in Imvepi,Compare Tree-Based Intervention characteristics across four NGOs in the Imvepi refugee settlement,Identify which specific tree-based intervention activities (in the categories of conserving, planting, and facilitated re-sprouting trees) each of four NGOs in Imvepi are engaged with,Compare Tree-Based Intervention activities among four non-governmental organizations in the Imvepi refugee settlement,
 USA 2023-05-04 16:39:21 2026-05-04 Natural Sciences Non-Clinical Trial Degree Award
Michio Matsuba Kyle
ID: UNCST-2022-R009027
 Wang Oo Relit Project (WORP) Evaluation Study
REFNo: SS1716ES

1. To determine if youth who participate in the WORP program show improvement on measures of well-being, 2. To monitor the level of engagement of youth in WORP lessons and activities 3. To understand the benefits and challenges associated with the WORP program from the perspective of youth participants.
 Canada 2023-05-02 22:28:11 2026-05-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fredrickson B Wasswa
ID: UNCST-2022-R008765
 MINION WHOLE GENOME SEQUENCING OF BLOOD FOR DIAGNOSIS OF MENINGITIS AT MBARARA REGIONAL REFERRAL HOSPITAL, UGANDA
REFNo: NS528ES

To determine the use of MinION WGS to identify antimicrobial resistant genes, virulence enzymatic genes and Single Nucloetide polymorphisms (SNPs) among patients with CM and TBM at MRRH, To compare the performance of full MinION flow cells with Flongle flow discs designed for smaller samples for detection of CM and TBM at MRRH. To determine the suitability of blood as an alternative to CSF for the detection Cryptococcus and MTB in patients CM and TBM using MinION WGS at MRRH,To compare Cryptococcus and TB detection from blood and CSF using MimION WGS from patients with CM and TBM at MRRH.,
 Uganda 2023-05-02 22:27:01 2026-05-02 Natural Sciences Non-Clinical Trial Degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Smart Discharges for Vulnerable Refugee Children: A Cohort Study to Validate Prognostic Algorithms for Post-discharge Readmission and Mortality among Children Living in Refugee Settings.
REFNo: HS2755ES

Primary Objective:

1. To validate, calibrate, and refine the Smart Discharges risk-prediction algorithm in a representative cohort of refugee children.

Secondary Objectives:

1. To describe the epidemiology of, and risk factors for, post-discharge mortality of children in the context of refugee settings.
2. To describe the post-discharge health seeking patterns of children in the context of refugee settings.

 Uganda 2023-05-02 22:24:41 2026-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Davis KATUMBA
ID:
Uncontrolled asthma among adolescents in selected secondary schools in Kampala City: Prevalence, associated factors, in-school needs, pathways to care and effectiveness of an mHealth Self-management app
REFNo: HS2791ES

To determine the effectiveness, acceptability and feasibility of the KmAsthma self-management app in improving the control of asthma among day scholar secondary school adolescents 12-19 years old in Kampala City Uganda.,To examine pathways to asthma care and their influence on asthma control among secondary school adolescents with asthma in Kampala City Uganda ,To establish the in-school needs associated with asthma control among adolescents in selected secondary schools in Kampala City Uganda ,To determine the prevalence of and factors associated with uncontrolled asthma among adolescents in selected secondary schools in Kampala City Uganda ,To establish the prevalence of and factors associated with uncontrolled asthma, in-school needs, pathways to asthma care, and effectiveness of KmAsthma Self-management app intervention to control asthma among adolescents in selected secondary schools in Kampala City Uganda,
 Uganda 2023-05-02 22:22:49 2026-05-02 Medical and Health Sciences Clinical Trial Degree Award
Martin Lukindu
ID: UNCST-2023-R008081
 One-Health analysis of CCHFV transmission risk patterns in Ugandan cattle corridor and arid Northern Kenya”
REFNo: A296ES

i) Identify tick spp diversity in diverse ecosystems of Ugandan cattle corridor
ii) Assess tick blood meal sources of potential vectors collected from unique spatial regions
iii) Delineate CCHFV infection rates of tick populations in diverse ecological units
iv) Characterize the tick virome of the Ugandan cattle corridor tick populations
v) Assess CCHFV genetic diversity at fine geographical and temporal scales across ecosystems

 Uganda 2023-05-02 22:19:16 2026-05-02 Agricultural Sciences Non-Clinical Trial Non-degree Award
Esau Tugume
ID: UNCST-2019-R000622
 Improving the Measurement of Productivity Dispersion and Misallocation in Developing Countries
REFNo: SS1698ES

6. Generate information and knowledge required to make informed policy decisions particularly in raising the productivity of small firms. ,Determine the role of firm-to-firm interactions, either as catalysts or hindrances to growth. ,Quantify the extent of resource misallocation across firms and the role of frictions in constraining firm growth.,Evaluate the strengths and weaknesses of existing empirical approaches to measuring misallocation. ,Verify whether existing estimates of productivity and marginal product dispersion are robust to improved measurement and the accounting of firm-to-firm interactions. If not, our data will identify the source of bias,Quantify three margins of allocative efficiency of firms: (i) the within-firm allocation of inputs across products, (ii) the allocation of resources across firms located in geographical proximity to each other, i.e., that operate within informal “clusters,” as widely documented in low-income country settings, and (iii) the sector-level allocation of resources across different geographic areas (or clusters).,The primary objective of this research project is to shed light on the organization of production in low-income countries and estimate firm-product level production functions. ,
 Uganda 2023-05-02 22:16:11 2026-05-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
John Kellett Gale
ID:
Can continuous non-invasive monitoring of movement predict and detect clinical deterioration of hospital patients earlier and more efficiently than traditional intermittent observations?
REFNo: HS2765ES

To determine if continuously collected accelerometer data can indicate and identify clinical deterioration of acutely ill hospitalised patients before intermittently collected vital signs.
 Ireland 2023-05-02 22:11:25 2026-05-02 Medical and Health Sciences Clinical Trial Non-degree Award
Stephen Pande Legesi
ID:
Sentinel Surveillance for Adverse Events of Special Interest after Vaccination with COVID-19 Vaccines-Uganda
REFNo: HS2370ES

Primary Objectives The overall aim of this surveillance protocol is to monitor the safety of COVID-19 vaccines in UGANDA in near real-time for pre-specified AESI conditions and evaluation to inform decision making to maintain public confidence in the vaccination program Specific Objective The specific objective of this evaluation is to assess the risk of pre-defined AESI following vaccination with a COVID-19 vaccine by brand. Secondary objectives 1.To strengthen Uganda’s active AEFI Surveillance system 2.To describe lessons learned from implementing active surveillance for various COVID 19 vaccine products.
 Uganda 2023-05-02 22:08:38 2026-05-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dorcas Mandera Agatha
ID:
Accelerating Impact for Young Women in Africa (AIM) Project Process Evaluation
REFNo: SS1644ES

- To identify contextual factors and success drivers that influence the program reach and quality,- To ascertain the effectiveness of the project from the perspective of its beneficiaries.,- To assess the viability of the intervention strategy and its feasibility as assumed in the theory of change (ToC).,This process evaluation intends to assess the implementation of the AIM project to ascertain whether it works, why it works, how it works, and its potential replicability. ,
 Uganda 2023-04-28 23:54:42 2026-04-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Lawrence Osuwat Obado
ID: UNCST-2023-R008389
 Assessing the Health Risk of Arsenic Burden in Human Beings and its Levels in Natural Water Sources Providing Domestic Water in Amuria District
REFNo: HS2770ES

To determine the arsenic concentration in hair samples taken from residents using water from sampled sources for domestic purposes,To determine the concentration of arsenic in the nails of residents using water from sampled sources for domestic purposes,To profile the arsenic levels of water from natural sources in areas of Amuria district in Eastern Uganda, and test for potential bioaccumulation of arsenic among the residents that use the water for domestic purposes,To determine the amount of arsenic in water collected from underground wells in Amuria District.
 Uganda 2023-04-26 11:43:03 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SSEDYABANE FRANK
ID: UNCST-2022-R011175
 ASSOCIATION OF FOXP3, P16INK4A, CMYC AND SELECTED MICRO RNA SERUM EXPRESSION WITH GRADES, TREATMENT STRATEGIES AND OUTCOMES FOR CERVICAL SQUAMOUS INTRAEPITHELIAL LESIONS
REFNo: HS2722ES

1. To determine the prevalence of Cervical Intraepithelial Neoplasia among women attending the cervical cancer clinic at Mbarara Regional Referral Hospital.
2. To establish the individual and combined accuracy of FOXP3, P16ink4a, cMYC, and selected micro RNAs (miR-205, miR-9, miR-192 and miR-21) in detection of cervical squamous intraepithelial lesions among women attending the cervical cancer clinic at Mbarara Regional Referral Hospital.
3. To determine the association between serum levels of FOXP3, P16ink4a, cMYC, and selected micro RNAs (miR-205, miR-9, miR-192 and miR-21) with grades of cervical squamous intraepithelial lesions among women attending the cervical cancer clinic at Mbarara Regional Referral Hospital.
4. To determine the relationship between follow-up serum levels of FOXP3, P16ink4a, cMYC, and selected micro RNAs (miR-205, miR-9, miR-192 and miR-21) and treatment strategies as well as outcomes (clearance, persistence or progression) of cervical squamous intraepithelial lesions among women attending the cervical cancer clinic at Mbarara Regional Referral Hospital.

 Uganda 2023-04-26 11:42:24 2026-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
 Assessing dynamics of heterosexual transmission of genital bacteria and coital impact on microbiome composition/stability in the female and male genital tracts in South-central Uganda
REFNo: HS2696ES

Primary objective
To elucidate the sexual transmission of genital bacteria and the determinants of the penile microbiome after sex.

Secondary objectives
A. To assess the strain variations of the triad and to characterize the different strains’ acquisition and carriage peri-coitus.
B. To identify abiotic and biotic factors from host (penile) and partner (vaginal) micro-environment that have a consistent and significant impact on penile microbiome composition.
C. To assess the short-term impact of standard anti-bacterial vaginosis (BV) treatment on the composition of the genital microbiome within heterosexual couples

 Uganda 2023-04-26 11:38:48 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Ssemata
ID: UNCST-2023-R008259
 Transitioning from pediatric to HIV adult care services and its impact on mental health and wellbeing for young people in Kampala: A scoping review and qualitative study
REFNo: SS1687ES

i.) To identify facilitators and barriers to successful transition process (socio-cultural, behavioural and health system factors) and how this influence adherence and virologic suppression among patients on ART.
ii.) To understand the experiences of healthcare providers and caregivers in providing care and supporting retention of young people on treatment during transition from paediatric to adult clinics.

 Uganda 2023-04-26 11:36:57 2026-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Ndeezi
ID: UNCST-2019-R001802
 Nutritional management of growth faltering in infants aged under six months. Study protocol for an individually randomised trial
REFNo: HS2766ES

To determine the effect of nutritional supplementation plus intensive breastfeeding support compared with intensive breastfeeding support alone on mortality, morbidity and growth in infants aged 0-6 months with growth faltering in low resource settings in South Asia and Sub-Saharan Africa.
Uganda 2023-04-26 11:15:23 2026-04-26 Medical and Health Sciences Clinical Trial Non-degree Award
Mnason Tweheyo
ID:
Baseline Study for the proposed Conservation and Rural Enterprise (CARE) Project in Bwindi Impenetrable National Park and Budongo Central Forest Reserve
REFNo: SS1703ES

The key objectives of the baseline survey include:

a) Identifying and tracking indicators that enable the assessment of a potential relationship between:
 The proposed interventions of the CARE project, namely the development and launch of a luxury eco lodge and establishment of supporting small to medium enterprises in the Bwindi and Budongo areas and;
 The status of social and economic wellbeing and environmental conservation in this region.
b) Tracking changes to social and economic wellbeing over the 18-month grant period.
c) Tracking the CARE project’s interventions in economic opportunities, such as the creation of small to medium enterprises, trainings offered, employees hired, wages and income earned.
d) Tracking the CARE project’s interventions in environmental sustainability and conservation, such as alternative fuel provision, replantings, environmental education and conservation training courses, and wildlife corridor development.
e) Comparing economic and environmental interventions to changes in social and economic wellbeing, as well as changes in the region’s environment.
f) Collecting baseline data on the identified indicators through surveys and earth observation imagery. This indicator data will be able to be collected again at the culmination of the research collaborative analysis period in 18 months, and indicators should be capable of being tracked again, in the future, in the possible eventuality of a longer-term research project.
g) Using the indicator data to develop a generalizable toolkit for the joint improvement of social and economic wellbeing and environmental conservation, which can be adapted to other rural contexts.


 Uganda 2023-04-26 11:13:44 2026-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 GENDER EQUALITY AND WOMEN LEADERSHIP IN HIGHER EDUCATION IN EAST AFRICA.
REFNo: SS1672ES

General objective: To establish the prevailing landscape of gender equality in universities in East Africa. Specific objectives: (1) To assess entry and completion rates of women in selected academic programs in universities in East Africa for the period 2012-2022. (2) To establish the status of female academic staff engagement in academia and research (e.g., publishing rates) and leadership in universities in East Africa for the period 2012-2022. (3) To examine existing mechanisms for promoting gender equity and women leadership (e.g., university-wide policies, practices, services) as well as success factors, challenges and barriers to gender equality in universities in East Africa.
Uganda 2023-04-26 11:12:07 2026-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abel  Kakuru
ID: UNCST-2022-R009193
 The immune response to malaria within the germinal center
REFNo: HS2717ES

Comprehensively map the germinal center immune landscape during malaria infection.

Identify key cells and processes required for and/or disrupting the induction of malaria germinal center and antibody responses.

Identify key cells and processes required for germinal center and antibody induction to vaccines that are disrupted by malaria.

Identify and test drugs that can boost germinal center responses appropriate for use in malaria exposed children.

 Uganda 2023-04-26 11:08:15 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Galvin
ID:
Improving HIV Outcomes through Collaborative Mental Health Interventions
REFNo: SS1642ES

To assess the perspectives of traditional and faith healers and biomedical mental health professionals on mental health treatment for people living with HIV/AIDS who have mental illness using a qualitative approach. We will interview 5-10 traditional healers and 5-10 faith healers over 2-4 months in early 2023. They will be recruited from the local area based on their experience working with people with HIV/AIDS and mental illness. These interviews will aid in characterizing the different conceptions of mental illness etiology and treatment strategies among both traditional healers in the African tradition and faith healers/pastors in the Christian tradition, and examine if collaboration between traditional and faith healers, and biomedical service providers can be developed to best serve people living with HIV/AIDS and improve health outcomes.,Objective 1b - To determine the characteristics of people living with HIV/AIDS and mental illness using a quantitative approach. We will collect cross sectional data on this population regarding of mental illness and HIV disease severity and duration, sociodemographics, and traditional and biomedical care history.,Objective 1a – To examine the experiences of people living with HIV/AIDS with mental illness in the Psychiatric Unit at Mbarara Hospital and traditional healer clinics using a qualitative approach. We will interview 15-25 patients living with HIV/AIDS and mental illness over 2-4 months in early 2023. They will be recruited from the psychiatric unit at Mbarara hospital. By interviewing mental health patients living with HIV, we can better understand how they view their illness, how local beliefs inform mental health care utilization, as well as their pathway to care and ultimately treatment outcomes.,To develop an intervention in which biomedical professionals collaborate with local traditional and faith healers to provide mental health services which will ultimately improve viral suppression, increase longevity, and reduce preventable morbidity and mortality.
 USA 2023-04-26 11:03:04 2026-04-26 Social Science and Humanities Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 An mHealth intervention to address the burden of depression and anxiety among perinatally-infected adolescents and young adults with HIV in Uganda.
REFNo: HS2691ES

Pilot U-SMART Voices among PAYWH with symptoms of anxiety and/or depression ,Adapt the group-based psychosocial mental health intervention, Sauti Ya Vijana (SYV; voice of the youth), to create the Uganda Social Media intervention to improve ART and Treatment outcomes (U-SMART)-Voices,Characterize the symptoms of depression and anxiety among PAYWH and correlation with quality of life.
 Uganda 2023-04-26 10:51:31 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phiona Bukirwa
ID: UNCST-2022-R009880
 Self-reported knowledge about palliative care offers and access to morphine by patients with cancer in Kyadondo County, Uganda
REFNo: HS2738ES

1. To assess patient knowledge of palliative care services. 2. To assess patient access to morphine and investigate the reasons for poor access 3. To describe the barriers to the intake of morphine,
 Uganda 2023-04-26 10:44:36 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eriab Kapuru Asinja
ID: UNCST-2022-R011430
 Title: Uptake of modern contraceptive methods and birth outcomes among women with caesarian sections in Kasese district, Uganda: leveraging innovative digital technology for empowering community health workers in delivering family planning services
REFNo: HS2639ES

4- To investigate the feasibility of using mobile phone health text messaging to women through CHWs and estimate the effect on contraception uptake among women in Kagando (sub-study IV),3- To explore women’s knowledge, attitudes and practices with various methods of contraception and evaluate the perceived benefits and satisfaction with contraception services, comparing those who had CS births and those who never had CS births (sub-study III),2- To estimate the frequency of repeat caesarian sections and factors associated with birth outcomes (sub-study –II).,1- To determine if CHWs can accurately document and follow households in defined geographical areas assigned to them (demographic surveillance area) using mobile phones and the feasibility of linking these data with hospital records (sub-study I).,The main objective of this study is to build the capacity of community health workers to accurately register households, including pregnant mothers and follow them with targeted health messages to improve birth outcomes,
 Uganda 2023-04-26 10:40:21 2026-04-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Simon Walusimbi
ID:
Impact of Tuberculosis Preventive Treatment (TPT) on Tuberculosis incidence and all-cause mortality among People Living with HIV (PLHIV) Receiving Anti-Retroviral Treatment (ART) in Uganda
REFNo: HS2772ES

To determine how long after TPT completion does TB incidence begin to rise again in patients who have completed TPT,To compare TB incidence and all-cause mortality among PLHIV who received TPT as 6-month INH versus 3HP regimen,To establish the risk factors for developing TB among PLHIV who have completed TPT,To compare TB incidence and mortality among PLHIV in Uganda who have completed TPT with PLHIV who have not completed TPT,To determine the incidence of all-cause mortality among PLHIV in Uganda who have completed TPT, at 12, 24, and 36 months of TPT completion.,To determine the incidence of newly diagnosed TB disease among PLHIV in Uganda who have completed TPT, at 12, 24, and 36 months after TPT completion,To evaluate the impact of TPT on TB incidence and all-cause mortality among PLHIV in Uganda,
 Uganda 2023-04-26 10:39:06 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles  Kajubi
ID: UNCST-2022-R008989
 Baseline Study for Safe and Inclusive Cities Project -Uganda.MAKSHSREC-2022-420
REFNo: SS1582ES

To measure the long-term impact of the intervetions on the project participants and formulate recommendations for Plan International Uganda to further strengthen research.,To determine the baseline values for outcome indicators from the onset of the project.,
 Uganda 2023-04-26 10:37:49 2026-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Muinda Emmanuel
ID:
An Information Technology Governance Framework for Improved Success of Digital Transformation Projects for Technical, Vocational Education and Training (TVET)
REFNo: SIR180ES

To test and evaluate the designed ITG Framework for Improved Success of Digital Transformation Projects in TVET institutions,To design and develop an ITG Framework for Improved Success of Digital Transformation Projects in TVET institutions,To determine the factors for improved success of Digital Transformation Projects in TVET institutions,To establish the effectiveness of Information Technology Governance applied in TVET institutions,The General Objective of this study is to develop an Information Technology Governance (ITG) framework for improved success of Digital Transformation Projects in the TVET subsector,
 Uganda 2023-04-26 10:31:45 2026-04-26 Engineering and Technology Non-Clinical Trial Degree Award
ELIZABETH ASIGE
ID:
THE IMPACT AND COST-EFFECTIVENESS OF A COMMUNITY-BASED PROGRAM FOR CHILDREN WITH CEREBRAL PALSY AND THEIR CAREGIVERS AND THE STAKEHOLDERS IN UGANDA.
REFNo: HS1979ES

1. To examine the impact of a community-based program on children with CP reported frequency of participation in the home, school, and community activities. 2. To assess the impact of a community-based training program on improving caregiver knowledge regarding CP and reducing caregiver stress. 3. To determine the impact of a communication and advocacy program in broadening stakeholders’ knowledge, attitude and practices regarding childhood disability and inclusion. 4. To determine the cost-effectiveness of a community-based program on children with CP, their caregivers, and the stakeholders in relation to costs and benefits.
Uganda 2023-04-20 21:15:22 2026-04-20 Medical and Health Sciences Clinical Trial Degree Award
Jedediah Silver
ID: UNCST-2023-R007939
 The Effects of Cassava Drying Technology on Commercialization and Consumption Smoothing
REFNo: SS1700ES

The main goals of the pilot RCT are to ascertain the technical efficiency of the machines, the viability of the model where agents operate the machines and charge a fee for drying, and to observe how harvest and sales timing, consumption and cropping decisions change when farmers gain access to drying technology. In addition, we will explore additional mechanisms including varying the contract structure, and getting a sense of which channels are most salient to focus on (e.g. how likely we would be to detect effects on intertemporal smoothing beyond addressing the barriers to adoption to a seemingly profitable technology).
 USA 2023-04-20 21:05:53 2026-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Beatrice  Onyango Ekesa
ID:
Bio-efficacy of Pro-Vitamin A-rich banana to improve vitamin A status among children in Uganda living in an area with a high burden of inflammation
REFNo: HS2721ES

3. Establish the stability of retinol isotopes on DSS at room temperature in the determination of TBS of vitamin A.,2. Assess the effect of inflammation and nutritional status on vitamin A absorption and TBS assessment among school-aged Ugandan children.,1. Determine the bio-efficacy of carotenoids in Pro-Vitamin A rich bananas in improving TBS in children aged 6-14years.,This study will determine the bio-efficacy of carotenoids in Pro-Vitamin A-rich banana-based diets and their potential in improving the vitamin A body stores by the RID technique among school-going children aged 6-14years living in Tororo district, an area with a high burden of inflammation.,
 Kenya 2023-04-19 12:44:24 2026-04-19 Medical and Health Sciences Clinical Trial Non-degree Award
Bernard Muhangi Wakabi
ID:
Managerial competences and performance of Microfinance Institutions in Uganda
REFNo: SS1693ES

iii. To establish the moderating effect of stakeholder management on the relationship between managerial competencies and financial performance of MFIs in Uganda.,ii. To examine the mediating effect of competitive advantage in the relationship between managerial competencies and financial performance of MFIs in Uganda.,i. To examine the relationship between managerial competencies and financial performance of MFIs in Uganda.,The study will examine the relationship between managerial competencies and financial performance while examining the mediating effect of competitive advantage and stakeholder management's moderating effect in the relationship between managerial competencies and financial performance of MFIs in Uganda.,
 Uganda 2023-04-19 12:41:29 2026-04-19 Social Science and Humanities Non-Clinical Trial Degree Award
Violet  Gwokyalya
ID: UNCST-2022-R010490
 An Evaluation Study of Oral PrEP Delivery Models in Uganda
REFNo: HS2734ES

Primary Objectives 1. To document Oral PrEP delivery models currently in use in Uganda. 2. To establish the contribution of the various Oral PrEP delivery models to uptake of PrEP. 3. To establish the contribution of the various Oral PrEP delivery models to continuity of PrEP. 4. To establish the costs involved in implementing different PrEP delivery models in Uganda. 5. To document the best practices from the different PrEP Delivery models and the recommendations for promoting efficient and sustainable PrEP services. Secondary objective. To establish the feasibility of injectable PrEP delivery in Uganda
Uganda 2023-04-19 12:27:39 2026-04-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
 A pilot etiological study of genital ulcer disease in Uganda, including the burden of macrolide resistant T pallidum
REFNo: HS2728ES

-To determine the proportion of genital ulcers caused by syphilis compared with other causes of genital ulcer disease in a contemporary Ugandan setting.
-To determine the proportion of T pal isolates with evidence of macrolide resistance markers.
-To determine agreement between clinical diagnosis and treatment compared with laboratory diagnosis of GUD.
-To determine agreement between GUD PCR result and serological markers of infection including POCT and lab-based assays.
-To develop a library of GUD pictures stratified by microbiological diagnosis.


 UK 2023-04-19 12:17:44 2026-04-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GODFREY TUMUHAISE
ID:
Rapid Assessment of Avoidable blindness /Disability in the Northern, Eastern and Western Regions of Uganda in people aged 50 Years and above
REFNo: SS1695ES

• To determine the causes of blindness and VI.,• To explore the relationship between disability and socio-economic status and eye health,To determine the prevalence of disability among the study population. ,• To assess factors affecting access to cataract surgical services by determining cataract surgical coverage.,• To determine the prevalence and distribution of blindness and VI in the study population.,To estimate the prevalence and causes of blindness and visual impairment among people aged ≥50 years in Uganda.,
 Uganda 2023-04-19 12:14:06 2026-04-19 Social Science and Humanities Non-degree Award
Carolyne Akello Agwau
ID: UNCST-2021-R013375
 The CATALYST Study: Catalyzing access to new prevention products to stop HIV
REFNo: HS2801ES

The overall goal of the study is to characterize and assess the implementation of an enhanced service delivery package providing choice of PrEP products among women at PEPFAR/USAID delivery sites in Kenya, Lesotho, South Africa, Uganda, and Zimbabwe. The study has three primary objectives: Objective 1: Characterize the implementation of the enhanced service delivery package for informed PrEP choice for women in PEPFAR/USAID public health service delivery sites and assess individual-, provider-, facility-, community-, and health system-level facilitators of and barriers to the implementation process. (Achieved through process evaluation, and nested costing and community acceptance studies) Objective 2: Describe patterns of PrEP use and use effectiveness in the context of informed PrEP choice and assess sociodemographic and contraceptive use correlates of PrEP use patterns. (Achieved through cohort and nested PEU study) Objective 3: Describe clinically relevant indicators among PrEP users, including rates of HIV infection and drug resistance among PrEP users who acquire HIV following PrEP initiation or had undetected HIV prior to PrEP initiation. (Achieved through cohort, including CAB HIV testing algorithm nested study)
Uganda 2023-04-13 16:51:59 2026-04-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Field Evaluation of National HIV Testing Services Algorithm
REFNo: HS2701ES

Main Objective
To determine the appropriate HIV rapid test algorithm to be used in Uganda considering the new kits on the market.

Specific objectives
1. To assess specificity, sensitivity, negative predictive value (NPV), positive predictive value (PPV) of the rapid HIV tests on the market in Uganda and come up with best RDT algorithm.
2. To identify an algorithm that will best identify acute HIV infections
3. To determine the inter-observer and inter-lab agreement in HIV diagnosis using evaluated RDTs.

 Uganda 2023-04-12 15:44:58 2026-04-12 Medical and Health Sciences Clinical Trial Non-degree Award
STUART TURANZOMWE
ID:
PREVALENCE, SEVERITY AND FACTORS ASSOCIATED WITH ANAEMIA AMONG WOMEN WITH CERVICAL CANCER AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2749ES

To determine the factors associated with anaemia among women with cervical cancer at Mbarara Regional Referral Hospital,To describe the severity of anaemia among women with cervical cancer at Mbarara Regional Referral Hospital,To determine the prevalence of anaemia among women with cervical cancer at Mbarara Regional Referral Hospital,To determine the prevalence, severity and factors associated with anaemia among women with cervical cancer at Mbarara Regional Referral Hospital,
 Uganda 2023-04-12 14:46:12 2026-04-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Samuel Kawuma
ID:
Facilitators and barriers to retention on Pre-exposure prophylaxis (PrEP) among Female Sex Workers attending Kiruddu National Referral Hospital.
REFNo: HS2771ES

1. To identify the implementation gaps along the Pre-Exposure Prophylaxis continuum of care and assess the factors associated factors with retention on PrEP among FSWs at Kiruddu National referral Hospital.,To design a stakeholder informed evidence-based intervention to improve retention on PrEP among FSWs at Kiruddu National Referral Hospital ,2. To determine the facilitators and barriers of retention on PrEP among FSWs in care at Kiruddu National referral Hospital.,
 Uganda 2023-04-12 14:43:04 2026-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 Protocol A5394: “Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with both Chronic Hepatitis B and HIV” Version 1.0, May 27, 2022
REFNo: HS2647ES

1.2 Primary Objectives

1.2.1 To assess the safety and tolerability of treatment with SLGN administered once weekly by mouth for 24 weeks.

1.2.2 To determine the proportion of participants with ≥1 log10 IU/mL decline in quantitative HBsAg (qHBsAg) after SLGN treatment at Week 24.

1.3 Secondary Objectives

1.3.1 To determine the proportion of participants with ≥1 log10 IU/mL decline in qHBsAg at any time during the study after SLGN treatment initiation.

1.3.2 To determine the proportion of participants with ≥0.5 log10 IU/mL decline in qHBsAg after SLGN treatment at Week 24.

1.3.3 To determine the proportion of participants with ≥0.5 log10 IU/mL decline in qHBsAg at any time during the study after SLGN treatment initiation.

1.3.4 To evaluate the proportion of participants who achieve HBsAg loss after SLGN initiation and who sustain HBsAg loss during follow-up.

1.3.5 To evaluate changes in qHBsAg levels at Weeks 4, 12, 24, 36, and 48 after SLGN initiation and, separately, among the placebo recipients.

1.3.6 To determine the proportion of HBeAg positive participants at baseline who lose HBeAg at any time during the study, by study arm.

1.3.7 To determine the proportion of anti-HBe negative participants at baseline who develop anti-HBe at any time during the study, by study arm.

1.3.8 To determine the proportion of hepatitis B surface antibody (anti-HBs) negative participants at baseline who develop anti-HBs at any time during the study, by study arm.
1.3.9 To evaluate levels of circulating cytokines, including IFN-gamma, IL-12p40, IL-1RA, and CD163 at entry, 24 hours post-first study drug dose, Weeks 4, 12, 24, 36, and 48, by study arm.

1.3.10 To determine whether administration of SLGN will perturb HIV latency as measured by an increase in HIV transcription.

1.3.11 To determine whether administration of SLGN will decrease the size of the latent reservoir, as measured by the change in amount of cell-associated unspliced HIV RNA, HIV DNA, replication-competent and/or intact virus at Weeks 2, 4, 24, and 48.

1.4 Exploratory Objectives

1.4.1 To define the pharmacokinetic (PK) profile and PK-pharmacodynamic (PD) associations of SLGN in people with both HIV and CHB taking suppressive antiviral therapy for both viruses.

1.4.2 To explore if SLGN and antiretroviral (ARV) PK are altered when administered together.

1.4.3 To evaluate participants’ adherence by using several tools, including self-report, directly observed therapy (DOT), and drug concentrations.

1.4.4 To compare quantitative changes in experimental measures of HBV antiviral efficacy (including HBV RNA, hepatitis B core related antigen [HBcrAg], qHBeAg, and low positive HBsAg measured with a high sensitivity qHBsAg assay [LLOQ of 0.05 IU/mL]) and measure changes in large, medium, and small HBsAg isoforms from baseline during and after treatment.

1.4.5 To determine the immunological effects of SLGN on circulating immune signaling by performing single cell RNA sequencing using peripheral blood mononuclear cells (PBMCs) and evaluating HIV-specific T-cell responses.

1.4.6 To determine the effects on circulating immune cells, including cellular phenotypes and T and B-cell responses.

1.4.7 To determine whether administration of SLGN will affect levels of circulating cytokines, including TNF-alpha, IL-12, IL18, IP-10, ISG15, IL-21, Fas Ligand, and TRAIL.

 Uganda 2023-04-12 14:38:49 2026-04-12 Medical and Health Sciences Clinical Trial Non-degree Award
Alex Mwesigwa
ID:
P. falciparum genetic diversity, multiplicity of infection, gametocytaemia and recrudescence in areas of varied malaria transmission intensity in Uganda.
REFNo: HS2744ES

1. To compare the genetic diversity and multiplicity of P. falciparum infections in areas of varied malaria transmission intensity in Uganda.
2. To evaluate the relationship between malaria severity and P. falciparum genetic diversity, multiplicity of infection among patients living in areas of varied malaria transmission intensity in Uganda.
3. To investigate the temporal and seasonality changes in P. falciparum genetic diversity and multiplicity of infection among patients with malaria infection living in areas of varied malaria transmission intensity in Uganda.
4. To evaluate the performance of microsatellites in differentiating P. falciparum recrudescence from new infections.

 Uganda 2023-04-12 14:27:32 2026-04-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Jane Frances Zalwango
ID:
Etiopathogenesis of Blackwater Fever in Budaka District, Uganda: a pilot study
REFNo: HS2752ES

a)To explore the aetiology of BWF in Budaka District b)To identify therapeutic interventions for the treatment of BWF
Uganda 2023-04-12 14:23:40 2026-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
 Evaluation of a Community Health Entrepreneur model in rural Uganda
REFNo: HS2196ES

4.3 General objective
To explore the role, reach, and scalability of CHE programme as a social franchise approach to address the issue of access to healthcare and potential embedment of the programme in the larger health system.

4.4 Specific objectives
1. To investigate health care seeking behaviour of residents in rural communities in Uganda, in order to assess community access, choice and use of health (care) services, service availability and quality, and experience of health care of households in villages in Uganda
2. To investigate the strengths and weaknesses of a CHE programme in communities which already have adopted this programme and the potential added value of a strengthened community health system by a CHE programme in communities without this programme
3. To investigate multi-stakeholder perceptions on the functioning, potential scale-up, and the possibility of integration of a social franchise approach in the larger health system in Uganda


 Uganda 2023-04-12 14:20:54 2026-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Protocol for the establishment of clinical specimen panel for WHO Prequalification performance evaluation of HIV serology assays
REFNo: HS2786ES

To establish an HIV specimen repository at ITM.,To register the specimens into a Biobank at ITM; ,To characterize the specimens for HIV and syphilis serostatus using standardized reference assays and algorithms at ITM;,To collect biological specimens from patients with known HIV serostatus or blood donors from different regions of the world to establish a WHO HIV specimen evaluation panel that will be used for the laboratory performance evaluation of HIV serology assays undergoing WHO prequalification assessment; ,The overall objective is to assemble a new WHO HIV specimen evaluation panel in collaboration with PELs and collaborating centers, which will be made accessible on demand to all the PELs conducting HIV or dual HIV-syphilis serology test evaluations for WHO prequalification.,
 Uganda 2023-04-12 12:56:08 2026-04-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Environmental Drivers of Pediatric Postinfectious Hydrocephalus in Western Uganda: Case-Control Study
REFNo: HS2699ES

The overarching objective of the study is to elucidate potential factors that underlie the ecological correlation between precipitation and PIH. Identification of these environmental intermediaries may elucidate potential targets for intervention to reduce the incidence of PIH.,
 Uganda 2023-04-11 15:42:30 2026-04-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 A multiple arm, multiple stage (MAMS), phase 2B/C, open label, randomized, controlled platform trial to evaluate experimental arms including an increased dose of rifampicin, an optimized dose of pyrazinamide, moxifloxacin and sutezolid, in adult subjects with newly diagnosed, smear-positive pulmonary tuberculosis
REFNo: HS2644ES

Primary Efficacy Objective:
Rifampicin- containing experimental arms (arms 1,2)
To evaluate whether one or more of two experimental regimens based on
optimized dose rifampicin, optimized dose of pyrazinamide, and moxifloxacin
given for 12, respectively 17 weeks, are superior to standard treatment given for
26 weeks, as assessed by time to sputum culture conversion to negative in liquid
media.
Sutezolid-containing experimental arm (arm 4)
 To evaluate whether the efficacy of an experimental regimen composed of
sutezolid, delamanid, bedaquiline, and moxifloxacin given for 17 weeks is
superior to standard treatment given for 26 weeks, as assessed by time to
sputum culture conversion to negative in liquid media.
Secondary Objectives This study’s secondary objectives are:
Efficacy
 To assess treatment efficacy based on proportion of patients with relapse
free outcome at 12 months after randomization.
 To assess treatment efficacy based on the rate of decline of bacterial load
measured by the Molecular Bacterial Load Assay
 To rank the relative efficacy of the experimental four-drug combinations
for the treatment of pulmonary tuberculosis within the first twelve weeks
of treatment, and select the most efficient experimental treatment
regimen or regimens for further development.
Safety and Tolerability
To assess the frequency, severity, and type of adverse events (AEs), and AErelated
treatment discontinuations.
Pharmacokinetics
To describe the pharmacokinetics of the drugs and doses used, and to assess
possible relationships between pharmacokinetic parameters of the various drugs and between pharmacokinetic parameters and participant characteristics.
Pharmacodynamics To describe relationships between pharmacokinetic parameters on the one hand and efficacy and safety endpoints on the other hand.
 Uganda 2023-04-11 15:27:11 2026-04-11 Medical and Health Sciences Clinical Trial Non-degree Award
Andrew Muhumuza
ID: UNCST-2022-R009010
 Incidence and predictors of castration resistance among patients with prostate cancer on androgen deprivation therapy at two referral hospitals in Uganda
REFNo: HS2759ES

To identify the predictors of castration resistance among prostate cancer patients on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital. ,To determine the incidence of castration resistance among patients with prostate cancer on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital.,To determine the incidence and predictors of castration resistance among prostate cancer patients on ADT at Mbarara Referral Hospital oncology unit and Uganda cancer Institute, Mulago National Referral Hospital.,
 Uganda 2023-04-11 14:20:29 2026-04-11 Medical and Health Sciences Non-Clinical Trial Degree Award
SAM ALI
ID: UNCST-2020-R014824
 Stillbirth in High Burden Settings: Ample Room for Improvement using Biomarkers and Ultrasound Technologies (iTECH)
REFNo: HS2762ES

1. To evaluate the relation between placental histopathological lesions and biomarkers, placenta ultrasound and hemodynamic changes after stillbirth and near miss stillbirth in order to understand the underlying mechanisms and specify the prediction model. 2. To engage with important stakeholders on the value of these diagnostic technologies in the community, co-creating the project design, implementation and eventual uptake into practice guidelines. 3. To establish the predictive performance of maternal characteristics and markers emerging from this project for stillbirth and other related endpoints in non-anomalous fetuses and assess the feasibility of integrating relevant markers into clinical decision support tools. 4. To prospectively evaluate patterns of (bio)markers, maternal cardiovascular function and contemporary ultrasound markers in pregnancy, to understand their role in the chain of events and pathophysiology of stillbirth in a resource poor setting. 5. To develop and validate a prediction model for use at the point of care in low-and middle-incomes countries (LMICs) to quantify a woman’s individual risk of antepartum stillbirth based on a set of easily measurable, accessible, highly predictive and cost-effective markers, and make it freely available for healthcare providers in low-resource settings.
 Uganda 2023-04-06 8:06:27 2026-04-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juliana Namutundu
ID:
IMPROVING CERVICAL CANCER SCREENING LITERACY AMONG HIV-INFECTED WOMEN IN CARE AT RURAL PUBLIC HEALTH FACILITIES IN EAST CENTRAL UGANDA
REFNo: HS2753ES

3) To assess the feasibility, acceptability and preliminary effectiveness of a cervical cancer screening literacy improvement implementation strategy for Women living with HIV in care at rural public health facilities in East Central Uganda.,2) To design a cervical cancer screening literacy improvement implementation strategy for Women living with HIV in care at rural public health facilities in East Central Uganda.,1) To conduct a multi-level assessment of barriers and facilitators of cervical cancer screening literacy among HIV-infected women in care at rural public health facilities in East Central Uganda.,
 Uganda 2023-04-05 17:05:10 2026-04-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Margaret Nafuna Sarah
ID:
EXAMINING MOTIVATIONAL STRATEGIES INFLUENCING PERFORMANCE OF TUTORS IN CORE PRIMARY TEACHERS’ COLLEGES IN EASTERN UGANDA
REFNo: SS1647ES

3. To analyse the challenges that may influence the effective motivation of tutors in Core PTCs in Eastern Uganda.,2. To examine the views of tutors on how motivational strategies affect their performance in Core PTCs in Eastern Uganda.,1. To investigate motivational strategies employed in Core PTCS in Eastern Uganda. ,
 Uganda 2023-04-04 9:36:11 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
Milcah Abasabyona
ID:
Intimacies of Identification and Lived Citizenship among the Ghetto Youths in Kampala, Uganda
REFNo: SS1654ES

Main Objective:
To investigate how citizen certification and identification influences levels of belonging to a place and space, impacts on citizen-state relationship and individual personhood.
Specific Objectives:
1. To capture the individual practical experiences of legal certification and identification processes among the Ghetto youths.
2. To examine the regulatory effects of identification documents on citizenship rights, a sense of belonging, and personhood among the Ghetto youths in Kampala.
3. To explore the different key Identification documents and their role in the day to day lives of the Ghetto Youths.
4. To trace the ways in which the undocumented Ghetto youths create alternative routes to lived citizenship and self-certification.
 Uganda 2023-04-04 9:32:41 2026-04-04 Social Science and Humanities Non-Clinical Trial Degree Award
ANYASE AMAZA RONALD
ID: UNCST-2022-R009325
 Development of a Natural Anti-Aflatoxin Product
REFNo: HS2692ES

To develop a prototype natural based anti-aflatoxin product made from Ugandan plants.,To establish a database of plants in Uganda with anti-aflatoxin potential,To determine the indigenous approaches of aflatoxin control in Uganda.,To develop a natural based anti-aflatoxin product ,
 Uganda 2023-04-03 21:04:19 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Professional Identity of Ugandan Nurses and Midwives: Exploring the understanding, Perceptions and Experiences among student Nurses and Midwives, Recent Graduates and Nurse Educators
REFNo: HS2712ES

Explore nurse and midwife top management in the ministry of health and nurses and midwives council perception and experiences fostering professional identity in nursing in the country.,3. Explore nurse and Midwife educators’ perceptions and experiences fostering professional identity in nursing and midwife at Mbarara University of Science and Technology and Makerere university,2. Explore challenges and barriers to professional identity formation at Mbarara University of Science and Technology and Makerere University,1. Describe the understanding of the professional identity of final year undergraduate nurses and midwives and recent graduates at Mbarara University of Science and Technology and Makerere University.,
 Uganda 2023-04-03 21:00:42 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
zaina Nakabuye
ID:
Technology orientation and the export performance of SME exporting firms in Uganda.
REFNo: SS1472ES

2. To establish the relationship between knowledge absorptive capacity and export performance.
3. To examine the relationship between supply chain agility and export performance.
4. To investigate the moderation of knowledge absorptive capacity between technology orientation and export performance.

5. To investigate the moderation of supply chain agility between technology orientation and export performance.

 Uganda 2023-04-03 20:58:43 2026-04-03 Social Science and Humanities Non-Clinical Trial Degree Award
Pooja Chitneni
ID: UNCST-2021-R012955
 Development and assessment of an HIV disclosure intervention for men in Uganda - Aim 1
REFNo: HS2682ES

Aim 1. Identify the unique HIV disclosure needs and preferences among MWH to support HIV disclosure. ,
 USA 2023-04-03 20:55:31 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 Prevalence of and factors associated with mental disorders and coping mechanisms among students at Busitema University.
REFNo: HS2700ES

To explore factors influencing mental disorders among students at Busitema UniversityTo explore the coping mechanisms used by students at Busitema University
 Uganda 2023-04-03 20:53:26 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Qualitative research to prepare for novel HIV prevention products
REFNo: HS1749ES

Define a preliminary strategy for the integration of novel PrEP products (e.g., injectable Cabotegravir, Dapivirine intravaginal ring, TFV/LNG intravaginal ring) into existing oral PrEP programs by conducting qualitative interviews with experts in novel PrEP products, oral PrEP programs, and end users.
To achieve this aim, we will conduct approximately 60 key informant interviews (KII) with: 1) clinical trialists leading studies of novel PrEP products, 2) oral PrEP program leaders in sub-Saharan Africa and 3) young women in Uganda who have decided not to use oral PrEP during recent PrEP studies.

Uganda 2023-04-03 20:51:28 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 Prevalence of intestinal colonization by ESBL-producing Enterobacterales in neonates at Jinja Regional Referral Hospital
REFNo: HS2737ES

• To highlight the area of antibiotic resistance in neonates in this setting ,• To conduct a point-prevalence surveillance of ESBL-producing Enterobacterales in the neonatal unit at two specific time-points with two weeks apart.,The overall aim of this project is to create base-line data for future infection prevention control strategies in the area of newborn care at Jinja Referral Hospital.,
 Uganda 2023-04-03 20:49:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Stella Maris Nanyonga
ID:
Optimizing antimicrobial use in the management of Upper Respiratory Tract Infections through antimicrobial stewardship in Community Pharmacy practice in Uganda; A patient centered approach
REFNo: HS2617ES

Primary Objectives 1. To assess the knowledge, attitude, and practice (KAP) towards self-medication among patients who visit community pharmacies for the management of Upper respiratory tract infections. 2. To explore the barriers and facilitators of self-medication in the community. 3. To explore prescriber views and understanding on the use of delayed prescribing in primary care. Secondary Objectives 4.To evaluate the effectiveness of training and delayed prescribing intervention on antibiotic consumption among patients with URTI who visit community pharmacies. 5. To describe dispensing and prescribing patterns of pharmacy staff when managing patients with upper respiratory tract infections at the community pharmacy
Uganda 2023-04-03 20:46:30 2026-04-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Kakayi Catherine
ID: UNCST-2022-R008787
 Insulin-like Growth Factor/Growth Hormone Levels and Stunting in HIV Exposed Uninfected Children from the 1077BF/P1084s study (CHASE: Changes in IGF/Hormone Axis and Stunting in HIV-Exposed uninfected children.
REFNo: HS2686ES

1. To investigate IGF-1, IGFBP-1, and IGFBP-3 as predictors of growth faltering/stunting in the first 2 years of life in HEU children

2. To describe the concentrations of hormonal growth factors in infants in relation to infant growth percentile at birth, 26 weeks, and 74 weeks of age.

Uganda 2023-04-03 20:41:44 2026-04-03 Medical and Health Sciences Clinical Trial Non-degree Award
Gerald Bareebe
ID:
Violence and Regime Trajectories in Post-Conflict Uganda and Rwanda
REFNo: SS1413ES

This study is driven by two important objectives: the first is the need to consider the influence of a “residue” social structure. What the cases of Uganda and Rwanda tell us is that, without understanding the underlying socio-political agency of the political regime and the armed elites that run it (and without knowing who their allies are or what the sources of constraints in that process are), it is difficult to resolve the socio-political problems that trouble most postwar states on the continent. The second is the need to show how post-war reconstruction in Africa is a function of elite interactions. The failure to understand this phenomenon has left post-conflict societies more vulnerable to conflict relapse. By investigating the interface of power elites in post-war state reconstruction, this research situates itself within a more empirical and contemporary African perspective and elevates the importance of social actors, specifically those whose actions reflect the intractability of power struggle. Specifically, the research seeks to achieve the following objectives:

 To understand the process of post-conflict state reconstruction in Uganda and Rwanda
 To understand factors that may hinder or enable the rebuilding of state institutions after a civil war.
 To compare the experience of Uganda and Rwanda with regards to how they both approached state reconstruction after a devastating civil war.
 To determine the nature and impact of policies taken by state-builders in both Uganda after the 1986 civil war and Rwanda after the 1991 genocide.

Uganda 2023-04-03 16:49:25 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy Allen Peter
ID: UNCST-2019-R001369
 Public Authority and International Development Uganda Programme Phase 2
REFNo: SS1678ES

Inductive theory-building through comparative applications,New curriculum development for scholars and development professionals,Reciprocal capacity-building in the academy and knowledge production,Reflexive policy-making and governance impact,Generate impact, knowledge exchange and capacity building through a public authority lens,
 UK 2023-04-03 16:41:36 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesse Rudy Lynn
ID: UNCST-2023-R008208
 Prevalence of property Grabbing among widows in Uganda
REFNo: SS1677ES

To establish the total number of people protected in the different project areas districts as a result of Redeem’s program interventions., 1)To understand the indirect consequences of attempted and successful land/property grabbing for widows and orphans in the aftermath of the events, 2)To ascertain the criminal, violent or other means used by perpetrators to victimize widows and orphans through grabbing property or land in Uganda., 3)To determine the prevalence of property grabbing from widows in targeted areas of Uganda, 4)To measure the annual burden of property grabbing in the selected case work areas ,
 USA 2023-04-03 15:40:08 2026-04-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
GRACE MARY KENYONGA
ID:
Attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda
REFNo: SS1473ES

General aim
Examine the attitudes towards the use of pre-exposure prophylaxis for HIV among women in Uganda.
Specific Objectives
1. Explore the attitudes women have towards PrEP
2. Identify the factors that influence the present attitudes towards PrEP
4. Identify other community variables that may encourage or constrain the uptake of PrEP.
6. Identify and recommend necessary interventions and measures to counteract any prevailing negative attitudes towards PrEP that may be prevailing in the community.

 Uganda 2023-03-28 1:00:59 2026-03-28 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
 Risk factors for severe schistosomal morbidity: an adult case-control study by the Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)
REFNo: HS2570ES

We hypothesise that factors at each step of the parasite life cycle interact to determine morbidity in schistosomiasis. The objective of this work is to investigate risk factors associated with advanced schistosomiasis morbidity among adults, using a case-control study.
UK 2023-03-24 2:35:04 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Birungi Edwin Mutahunga Rwamatware
ID: UNCST-2021-R004880
 Prevalence and predictors of antimicrobial resistance in clinical- and community-acquired upper respiratory bacterial samples in children under 5 in south-western Uganda
REFNo: HS2625ES

Upper respiratory infections are the second leading cause of death in children under 5 in Uganda, and account for 40% of all under-5 outpatient attendance at clinics and hospitals nationwide in Uganda. As bacterial cultures of lung aspirates are often not practical, the WHO recommends using a rapid breathing and chest wall in-drawing to diagnose pneumonia in children under 5, and recommends treatment with oral amoxicillin or co-trimoxazole, or intramuscular penicillin. The only study of anti-microbial resistance (AMR) in nasopharyngeal bacteria in Uganda comes from healthy children in the Iganga/Mayuge region (Eastern Uganda), where the authors found that one-third of children were given a self-prescribed antibiotic within the past two weeks for fever, running nose, or cough, that 60% carried Streptococcus pneumoniae, and that a high proportion (80% to 99%) of cultures were resistant to co-trimoxazole, penicillin, and oxacillin. At Bwindi Community Hospital, suspected acute respiratory infections accounted for 75% of all under-5 outpatient diagnoses in 2015/2016, and are the most common reason for under-5 admissions to the Pediatrics Ward (e.g., 34% of 830 admissions in 2015/2016). In addition, the majority of antibiotics prescribed for both children and adults were for suspected acute respiratory illness (5,273 of 17,910 prescriptions). Our proposed study seeks to build on previous work concerning Antimicrobial Resistance in the developing world with a specific focus, on clinical- and community-acquired upper respiratory bacterial infections in children under 5 in southwestern Uganda, and it will be the first to analyse spatio-temporal patterns of resistance and explicitly link those patterns to cultural and social characteristics and behaviours on the ground as well as healthcare infrastructure. We propose a multi-layered study to; 1) Analyze the prevalence and spatial associations of antibiotic resistance in nasopharyngeal bacterial isolates from children under 5 in the Bwindi Community Hospital (BCH) catchment area for a year in Kanungu District, Southwestern Uganda. 2) Assess the use of antibacterial drugs at home to treat acute respiratory illness in these children from children under 5 in the Bwindi Community Hospital (BCH) catchment area in Kanungu District 3) Assess practices of antibiotic distribution at drug shops in the BCH catchment region.
Uganda 2023-03-24 2:31:31 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 Investigating determinants of varying schistosomal morbidity among preschool-age children in the Lake Albert and Lake Victoria regions: a cohort study by the Uganda Schistosomiasis Multidisciplinary Research Center
REFNo: HS2568ES

Our main objective is to understand the biological determinants of severe Schistosoma mansoni-associated morbidity and to identify better strategies for its prevention and control. Our specific objectives are to: 1. Compare, in pre-school age children, early-life Sm infection and Sm-specific immune responses between Lake Albert and Lake Victoria regions and identify co-exposures that modulate Schistosoma mansoni-specific immune responses and morbidity risk 2. Determine if there is a parasite genetic basis for differential Schistosoma mansoni morbidity 3. Determine how the population biological determinants of fresh-water snail Biomphalaria spp. act as local epidemiological drivers of Schistosoma mansoni
 UK 2023-03-24 2:29:21 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olive Kobusingye Chifefe
ID:
Building the evidence-base for the integration of rehabilitative services into health systems – a case study of clubfoot treatment in Uganda
REFNo: HS2614ES

The study has two aims, each with subsequent research questions: Aim 1: To explore how policy makers, health providers, and caregivers define, understand and experience service integration and the potential implications for clubfoot treatment. (Qualitative) • How do health care providers define and experience service integration, and what are the impacts of integration on their day-to-day clinical operations, workflow, and roles? • How do district- and national-level bureaucrats and donors understand integration, and how does that shape integration of clubfoot treatment? • How do caregivers understand and experience integration, and how does it impact their child’s treatment? • How is the NCPU financed and what relationship does financial contribution have with integration? Aim 2: To improve understanding of how the CAST mobile health application (CAST) impacts health providers’ behavior, and what potential impacts the CAST could have on service quality. (Mixed) • What is the reach and adoption rate of CAST and its components among eligible Ugandan providers? • How might CAST modify provider behavior at the facility level, both for clubfoot treatment and other services? • How might the CAST facilitate quality of care and patient treatment? o How do supportive services from MiracleFeet/CoRSU contribute to this? (e.g. training, supportive supervision, help desk) o How does data from and usage of the Cast Community contribute to this? • What is the potential future of the CAST if external support is withdrawn from clubfoot treatment and all services are fully managed by the public sector?
Uganda 2023-03-24 2:25:26 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent Rheumatic Heart Disease: A non-inferiority randomized trial. (GOALIE)
REFNo: HS2659ES

Primary Objective:
To compare the proportion of children aged 5-17 years with latent RHD receiving oral penicillin prophylaxis who progress to worse valvular disease at 2-years compared to children who receive IM penicillin prophylaxis.

 Uganda 2023-03-24 2:23:26 2026-03-24 Medical and Health Sciences Clinical Trial Non-degree Award
Samuel Ojelel
ID: UNCST-2019-R000996
 Tropical Important Plant Areas of Uganda
REFNo: NS479ES

(i) To assess conservation status of priority plant species to guide Identification of Important Plant Areas

(ii) To promote sustainable use and protection of Important Plant Areas by developing partnership with key stakeholders

 Uganda 2023-03-24 2:17:32 2026-03-24 Natural Sciences Non-Clinical Trial Non-degree Award
Denis Muhangi
ID: UNCST-2020-R014258
 A STUDY ON CONDOM DEMAND, UTILIZATION, DISTRIBUTION AND DISPOSAL SURVEY 2022
REFNo: SS1605ES

1. To establish the condom demand for both the male and female condom users in the community programming in 61 districts of Uganda 2. To generate information on distribution and utilization of condoms among key, priority and general population in 61 districts of Uganda 3. To generate data to be used to fill gaps in comprehensive condom programming in relation to condom demand, distribution, management and disposal as well as modalities for strengthening condom logistics in Uganda 4. To explore new modalities for strengthening condom logistics among the non-traditional channels of condom distribution in the community. 5. To determine the extent of adherence to the condom waste management and disposal mechanisms developed by MoH, 6. To establish status and opportunities of using the Total Market Approach
 Uganda 2023-03-24 2:13:39 2026-03-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Caroline  Nerima
ID:
FUNCTIONAL LIMITATIONS AMONG CHILD REFUGEES WITH DEVELOPMENTAL DISABILITIES AND BARRIERS TO EARLY CHILDHOOD INTERVENTION IN A UGANDAN REFUGEE SETTLEMENT.
REFNo: HS2666ES

1. To describe the functional limitations among children aged 1 month to 6 years with developmental disabilities.
2. To describe the early intervention services available for children with developmental disabilities living in refugee camps.
3. To describe the barriers to access to early intervention services for children with developmental disabilities.


Uganda 2023-03-24 2:10:43 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Winnie  Muyindike R
ID: UNCST-2021-R013558
 Tuberculosis, Alcohol, and Lung Comorbidities (TALC) Study
REFNo: HS2705ES

Qualitatively evaluate factors for tailoring pharmaco-behavioral alcohol and smoking interventions in PLWH being treated for TB. ,Explore how smoking alters the association of past-month heavy drinking and post-TB lung disease progression over time,• Aim 1b. Assess the association of past-month heavy drinking and post-TB lung disease progression over time. This aim uses recent alcohol use (30-day Timeline Followback, PEth) since direct mechanisms (e.g., alcohol toxicity) may drive the physiologic, anatomic, and immunologic outcomes of interest. We define past-month heavy drinking as ≥7 drinks/week (women), ≥14 drinks/week (men) or PEth>200 ng/mL.,• Aim 1a. Determine if past-year hazardous drinking is associated with post-TB lung disease. ,Aim 1. Determine the relationship between hazardous drinking and post-TB lung disease in PLWH.,
 Uganda 2023-03-24 2:08:05 2026-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Denis Muhangi
ID: UNCST-2020-R014258
 Sustainable Off-Grid Solutions for Pharmacies and Hospitals in Africa (SophiA). Sub-component 1: Needs Assessment of Hospitals/Health Centre IVs for the Sustainable Off-Grid Solutions Sub-component 2: Socio-Economic Acceptance and Participation Assessment for Stakeholders Sub-component 3: Life Cycle Assessment and Sustainability Assessment
REFNo: SS1627ES

Goal of the SophiA Project: To bring environmental, economic, social and health benefits, creating new business and job opportunities through new technological solutions; to support African countries to pursue sustainable pathways of development through a low-carbon, climate resilient and green growth trajectory, leapfrogging fossil fuels and high GWP refrigerant technologies; and to improve the quality of life of populations through better treatment and working conditions in rural and remote health facilities in Africa.

Specific Objectives of the Proposed Studies:
i) To assess the needs from several health stations in order to identify and match the most significant and suitable health station which can be served by one SophiA system, considering different uses, replicability, cost and constraints as pertains energy consumption and solar radiation.
ii) To assess the level of acceptance of the SophiA technological solutions by the relevant stakeholders including beneficiary communities, local leaders, health care providers and managers, district officials, and national level decision makers/policy makers.
iii) To conduct a Life Cycle Assessment (LCA) to evaluate the different environmental impacts and calculate the CO2 emissions for each of the SophiA technology: solar thermal, solar PV, thermal storage, electrical storage, ice storage, refrigerators).
 Uganda 2023-03-24 2:04:40 2026-03-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Esther Nasuuna Michelle
ID:
The Epidemiology of Chronic Kidney Disease among young people living with HIV in Uganda
REFNo: HS2578ES

1. To describe the prevalence of CKD among YPLHIV in SSA. 2. To compare the prevalence and associated factors of CKD diagnosed with cystatin C or creatinine-based estimates among YPLHIV in Uganda.
3. To describe the comorbidities associated with CKD among YPLHIV in Uganda.
Uganda 2023-03-22 15:08:26 2026-03-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Bangirana
ID:
Blood-Biomarkers and Risk Factors of Acute Brain Injury associated with Neurodisability in Ugandan Children (BRAIN-Child)
REFNo: HS2628ES

Determine if elevated brain injury biomarkers in pediatric TBI correlate with post-discharge mortality or neurocognitive impairment (NCI) and health-related quality of life outcomes at 6-month follow-up,Determine if biomarkers and risk factors of brain injury elevated in pediatric CM are elevated in pediatric TBI,
 Uganda 2023-03-21 3:29:20 2026-03-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Simon  Kasasa
ID: UNCST-2021-R012861
 A National Survey to Determine the Prevalence of Latent and Active Tuberculosis, COVID-19 and HIV Among Prisoners and Prisons Staff in Uganda Prisons
REFNo: HS2373ES

Overall objective
To determine the burden and associated factors of TB, COVID-19, and HIV among inmates and staff in Uganda prisons in order to generate evidence that will inform future interventions.
Primary objectives
i. To estimate the prevalence and associated factors of LTBI among inmates and staff in the Uganda prisons.
ii. To determine the prevalence and associated factors of active TB disease among inmates and staff in Uganda prisons.
iii. To determine the current burden of COVID-19 among prisoners and staff using an integrated TB and COVID-19 screening and testing approach.
iv. To establish the burden of past COVID-19 infection among prisoners and staff in Uganda prisons.
v. To determine the prevalence of HIV among inmates and staff in Uganda prisons.
vi. To determine HIV program achievement and gaps in the Uganda Prisons in reference to the UNAIDS targets for HIV testing, positive individuals who are on treatment, and PLHIV with suppressed viral load (95-95-95).

Uganda 2023-03-21 3:23:05 2026-03-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moreen Kabarungi
ID:
A FRAMEWORK TOWARDS THE IMPROVEMENT OF ADOPTION OF BLENDED LEARNING IN HIGHER EDUCATIONAL INSTITUTIONS CASE STUDY OF SOUTH WESTERN UGANDA.
REFNo: SS1665ES

The main objective of this study is to develop a framework to support the adoption of blended learning in higher educational institutions in south western Uganda.

The specific objectives are;
1. To establish the strengths, weaknesses and elicit the requirements of the existing blended learning frameworks and their level of usage and satisfaction in higher educational institutions.
2. To design a framework that supports the adoption of blended learning in higher educational institutions.
3. To evaluate the feasibility, acceptability and usage of the designed framework of blended learning in higher educational institutions.

 Uganda 2023-03-21 3:19:16 2026-03-21 Social Science and Humanities Non-Clinical Trial Degree Award
Tonny Ssekamatte
ID: UNCST-2022-R010961
 Understanding the barriers and facilitators to access and utilisation Sexual and Reproductive Health services among vulnerable/marginalized adolescents and young people in Uganda
REFNo: SS1673ES

To investigate the barriers and facilitators to access and utilisation Sexual and Reproductive Health services among vulnerable/marginalized adolescents and young people in Uganda ,Examine the role of social media/other sources in the spread of information and/or disinformation and how it potentially influences access to and use of SRH services.,Examine the role of social norms in influencing the use/non-use of SRH services among the populations of interest:,Explore the barriers and facilitators to accessing SRH services among vulnerable/marginalized 15–24-year-old adolescents and young people.,
 Uganda 2023-03-21 3:16:17 2026-03-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Annet Nanungi Kabuye
ID:
An mhealth framework for cancer surveillance in Uganda
REFNo: HS2695ES

To develop an mhealth data framework for cancer surveillance in Uganda.,
 Uganda 2023-03-21 3:06:26 2026-03-21 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth (Betsy) Ness-Edelstein Ann
ID:
Cooperative Development Program Evaluation
REFNo: SS1664ES

Assess how the specific work of Health Partners in Uganda is contributing to the overall program objectives,● Contribute to the evidence base on effective cooperative development approaches.,● Identify the assumptions or gaps in the project’s design or management approach to help inform a new project design,● Illuminate ways in which the entire project is making progress toward the stated Project Purpose or not,
 USA 2023-03-21 3:04:41 2026-03-21 Social Science and Humanities Non-Clinical Trial Non-degree Award
Edward Mokooza Kibikyo
ID: UNCST-2020-R014923
 Understanding Barriers and Facilitators to Establishing Palliative Care Units at Hospitals in Uganda.
REFNo: SS1510ES

4. To identify the facilitators of establishing palliative care units in hospitals in Uganda. ,3. To describe barriers to the establishment of palliative care units in hospitals in Uganda.,2. To document the functionality of existing PC units in hospitals in Uganda. ,1. To determine the proportion of public and private hospitals with PC units.,
 Uganda 2023-03-16 13:06:27 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Zhubin Chen
ID:
The Impact of Social Health Insurance on the Incentives of Health Care Providers in East Africa: A Mixed-methods Approach
REFNo: SS1574ES

1.1 Describe how social health insurance functions and how health care providers respond to the economic incentives of social health insurance in Rwanda, Kenya, and Uganda 1.2 Pose hypotheses based on 1.1 and test them empirically using nationally representative data 2. Follow different institutional actors (ministry of health, health facilities, NGOs, and community organizations) and describe how they perceive the function of social health insurance in Rwanda, Kenya, and Uganda 3. Compare the impact mechanism of social health insurance in Rwanda, Kenya, and Uganda and document how the impact evolves on different paths and at different stages towards UHC
China 2023-03-16 13:04:14 2026-03-16 Social Science and Humanities Non-Clinical Trial Degree Award
Peace Tumuheki Buhwamatsiko
ID:
Experiences of students combining work and study at Ugandan universities
REFNo: SS1646ES

To explore experiences of students who combine work and study at both private and public universities in Uganda with a view of making recommendations that will contribute to improving their university education experience and promote inclusive lifelong learning agenda in higher education,To explore and examine the suitable academic and administrative supports for students combining work and study,To explore the classroom learning experiences of students who combine work and study,To uncover the motivations underlying the decision to combine work and study at university and the associated benefits and challenges,
 Uganda 2023-03-16 13:02:52 2026-03-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 Implementation of an eRegistry Enabled Transition from Four to Eight Antenatal Care Contacts - a Cluster-Randomized Controlled Trial in Mukono and Buikwe, Uganda (eReg4ANC8)
REFNo: HS2662ES

III. Undertake a cRCT of the new ANC8 vs. the current ANC4 schedule for low-risk pregnancies, to estimate its impact on quality of care, health, and satisfaction.,II. To assess and respond to factors across the i-PARIHS and COM-B domains to guide the facilitation of feasibility, acceptability, fidelity, and effectiveness of implementation of digitally enabled ANC8 at scale. ,I. To assess and respond to factors across the PARIHS and COM-B domains to guide the facilitation of feasibility, acceptability, fidelity, and effectiveness of the implementation of DHIS2 eRegistries for ANC at scale. ,
 Uganda 2023-03-16 13:01:11 2026-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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