Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
 Optimizing the Implementation and Scale-Up of the WHO Treatment-Decision Algorithms for Children with Pulmonary Tuberculosis in Sub-Saharan Africa (OPTIC-TB)
REFNo: HS5246ES

1) To compare the effectiveness of TDA versus the Standard of Care strategies in routine non-research programmatic conditions.
2) To identify processes and contextual factors that influence the effectiveness and fidelity in the implementation of TDA.
3) To compare the costs, cost-effectiveness, and population-level impact of the TDA strategies on the burden of TB.
4. To estimate/validate the diagnostic performance (sensitivity, specificity, negative and positive predictive values) of the TDAs for TB in children under 10 years old in various healthcare system settings and in various clinical contexts (i.e, such as HIV, malnourished children, facility level, gender, rural, urban etc.

Uganda 2024-12-10 14:06:31 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vianney Tushabe John
ID: UNCST-2024-R015708
 Development of Multiplex Molecular Test for S. mansoni and P. falciparum Duplex using LAMP assay and Pit Latrine metagenomic sampling for community assessment
REFNo: SIR445ES

- Development of the Multiplex Malaria – Schistosomiasis assay
- Latrine Metagenomics for community diagnostics assessment 
- Validation of Molecular duplex assay technology 
 Uganda 2024-12-10 14:04:09 2027-12-10 Engineering and Technology Non-Clinical Trial Degree Award
Manon Delvaux Alizee
ID: UNCST-2024-R002311
 Cultivating Cooperation: The Impact of Formalizing Land Rental Contracts on Refugee-Host Interactions and Agricultural Production in Rural Uganda
REFNo: SS3408ES

In northern Uganda, food insecurity is high for many refugees, who cultivate land for their subsistence in the vicinity of the settlements. A large majority of these refugees do not have a formal written land rental contract with their landlords. While informal institutions and agreements can have enforcement power in socially and culturally homogeneous groups, their efficiency tends to decrease with social and cultural distance. In this setting of cohabitation between Ugandans and refugees, the absence of clearly defined terms of trade often limits successful farming outcomes, as refugees’ rights to what they earn, produce, and consume are more vulnerable to changes. Suggestive evidence indicates that formal land contracts grant greater security, which can lead to increased farm profitability, investment and credit opportunities, and greater economic diversification and growth.

We will conduct a randomized pilot evaluation to measure the impact of formalized land rental contracts between refugee tenants and host community landlords. In the treatment groups, the landlords and tenants will receive support to formalize their land rental agreement. In the control group, landlords and tenants will remain with verbal and informal land rental agreements. We will evaluate indicators such as trust, social cohesion, agricultural practices, and food security. The study will also investigate why formalized land rental contracts are not more widespread in rural Uganda. The sample will include tenants from the Bidibidi, Imvepi and Rhino refugee settlements and landlords from the host communities.
 France 2024-12-10 14:03:00 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
SAM ALI
ID: UNCST-2020-R014824
 A Noncontact Bed-Based Platform for Passive Longitudinal Monitoring of Maternal and Fetal Cardiovascular Physiology in Uganda
REFNo: HS5320ES

Main objective
• To monitor maternal and fetal heart rate, respiratory rate, fetal movement, and sleep patterns among selected pregnant women enrolled in the iTECH study using noncontact bed sensors with the goal of better understanding both maternal and fetal physiology.

Specific objectives
1. To describe the maternal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
2. To describe the fetal respiratory and heart rate profiles among selected pregnant women enrolled into the iTECH study.
3. To demonstrate the feasibility of measuring and extracting fetal movement signals among selected pregnant women enrolled into the iTECH study.
 Uganda 2024-12-09 13:22:54 2027-12-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Disentangling the population structure of MRSA in an urban low-income settings
REFNo: HS4699ES

1. To define the population structure of MRSA in hospital and community settings in Kampala, and identify risk factors for MRSA carriage among inpatients and individuals in the community.

2. To Investigate the probable coexistence between HA-MRSA and CA-MRSA in hospital and community in Kampala.
 Uganda 2024-12-02 17:33:35 2027-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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