Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Maria Magdalene Namaganda
ID: UNCST-2021-R004319
Development of a machine learning model for prediction of virological failure in a resource-limited setting
REFNo: HS3982ES

Sub-study 1 To identify the risk factors associated with virological failure among PLWH in east Africa from 2014 to 2024. Sub-study 2 To analyse the trends of ART use and incidence of virological failure rates among PLWH in TASO-Uganda health centres from 2014 to 2024. Sub-study 3 To develop and validate machine learning models for prediction of virological failure. Sub-study 4 To evaluate the practical utility of the HIV virological failure predictive models developed in a clinical setting.
Uganda 2024-12-10 14:40:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackson Orem
ID: UNCST-2021-R012016
A Phase III, Randomized, Open-Label, Non-Inferiority Study of Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma in Resource-Limited Settings
REFNo: HS4073ES

To describe the incremental cost-effectiveness ratio per QALY gained (as assessed by PROPr) between PLD and PTX,To assess quality of life across PROMIS domains (i.e., cognitive function, physical function, fatigue, pain interference, depressive symptoms, anxiety, ability to participate in social roles and activities, and sleep disturbance) with the PROPr tool at start of therapy, mid-treatment, and after treatment with PLD and PTX ,To describe the cost of therapy across AMC sites in sub-Saharan Africa to deliver both PLD and PTX by micro-costing analysis for goods and time-in-motion analysis for services. ,To estimate the objective response rate (defined as the sum of complete and partial responses) for AIDS-KS, response duration and overall survival in each treatment arm. ,To evaluate whether there is sufficient evidence to conclude that PLD is non-inferior to PTX in people with severe AIDS-associated KS receiving concomitant ART in resource-limited settings. ,
Uganda 2024-12-10 14:39:24 2027-12-10 Medical and Health Sciences Clinical Trial Non-degree Award
Adelline Twimukye
ID: UNCST-2019-R000117
HIV CARE AND ANTENATAL HEALTH SEEKING BEHAVIOUR PATTERNS OF PREGNANT AND BREAST-FEEDING WOMEN DURING PREVIOUS COVID-19 PANDEMIC IN UGANDA
REFNo: SS3219ES

To document the challenges faced by pregnant and breastfeeding women with HIV in accessing healthcare services in the COVID-19 period.,To interrogate the effects of COVID-19 pandemic to adherence to routine clinic appointments and antiretroviral therapy (ART) among pregnant and breast-feeding women living with HIV.,To examine the social or cultural norms that influence access to care among pregnant or breast-feeding women HIV during the COVID-19 pandemic.,To investigate health care worker’s knowledge, attitude, and practices about COVID-19 among pregnant and breast-feeding women living with HIV in Uganda.,The purpose of the study is to explore HIV care and antenatal seeking behavior patterns of pregnant and breast-feeding women during response and control of COVID-19 pandemic in Uganda.,
Uganda 2024-12-10 14:37:39 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
VICENT MWESIGYE
ID: UNCST-2024-R002866
LYMPHEDEMA: CAUSATIVE AGENTS, PATIENT AND CARETAKER KNOWLEDGE, SELF-REPORTED HEALTHCARE NEEDS AND PREVENTIVE STRATEGIES IN KAMWENGE DISTRICT.
REFNo: HS5335ES

3. To explore the lymphedema-related knowledge, lived experiences and healthcare needs of patients and their caretakers and preventive strategies in Kamwenge district, South Western Uganda.,2. To determine the causative agents of lymphedema among patients with lymphedema in Kamwenge district, South Western Uganda.,1. To describe the Preventive strategies, their effectiveness in patients with Lymphedema based on Scoping review globally.,To determine the causative agents, patient and caretaker knowledge, self-reported healthcare needs and preventive strategies amongst Lymphedema patients in Kamwenge District South Western Uganda.,
Uganda 2024-12-10 14:35:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Tess Lallemant
ID: UNCST-2023-R007159
How do Firms Hire? A Demand-Side Experiment to Reduce Matching Frictions in Uganda Labor Markets
REFNo: SS3487ES

1. Answer the research question: How do firms navigate the hiring process for graduate workers?
2. Answer the research question: How are firms identifying their employment needs?
3. Answer the research question: How are firms communicating their employment needs?
4. Answer the research question: To what extent are these hiring frictions affecting match quality?
5. Answer the research question: Do firms learn about hiring and adapt their search strategies to achieve higher match quality?
USA 2024-12-10 14:24:53 2027-12-10 Social Science and Humanities Non-Clinical Trial Degree Award
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