Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Simon Walusimbi
ID:
Impact of Tuberculosis Preventive Treatment (TPT) on Tuberculosis incidence and all-cause mortality among People Living with HIV (PLHIV) Receiving Anti-Retroviral Treatment (ART) in Uganda
REFNo: HS2772ES

To determine how long after TPT completion does TB incidence begin to rise again in patients who have completed TPT,To compare TB incidence and all-cause mortality among PLHIV who received TPT as 6-month INH versus 3HP regimen,To establish the risk factors for developing TB among PLHIV who have completed TPT,To compare TB incidence and mortality among PLHIV in Uganda who have completed TPT with PLHIV who have not completed TPT,To determine the incidence of all-cause mortality among PLHIV in Uganda who have completed TPT, at 12, 24, and 36 months of TPT completion.,To determine the incidence of newly diagnosed TB disease among PLHIV in Uganda who have completed TPT, at 12, 24, and 36 months after TPT completion,To evaluate the impact of TPT on TB incidence and all-cause mortality among PLHIV in Uganda,
Uganda 2023-04-26 10:39:06 2026-04-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Charles  Kajubi
ID: UNCST-2022-R008989
Baseline Study for Safe and Inclusive Cities Project -Uganda.MAKSHSREC-2022-420
REFNo: SS1582ES

To measure the long-term impact of the intervetions on the project participants and formulate recommendations for Plan International Uganda to further strengthen research.,To determine the baseline values for outcome indicators from the onset of the project.,
Uganda 2023-04-26 10:37:49 2026-04-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Muinda Emmanuel
ID:
An Information Technology Governance Framework for Improved Success of Digital Transformation Projects for Technical, Vocational Education and Training (TVET)
REFNo: SIR180ES

To test and evaluate the designed ITG Framework for Improved Success of Digital Transformation Projects in TVET institutions,To design and develop an ITG Framework for Improved Success of Digital Transformation Projects in TVET institutions,To determine the factors for improved success of Digital Transformation Projects in TVET institutions,To establish the effectiveness of Information Technology Governance applied in TVET institutions,The General Objective of this study is to develop an Information Technology Governance (ITG) framework for improved success of Digital Transformation Projects in the TVET subsector,
Uganda 2023-04-26 10:31:45 2026-04-26 Engineering and Technology Non-Clinical Trial Degree Award
ELIZABETH ASIGE
ID:
THE IMPACT AND COST-EFFECTIVENESS OF A COMMUNITY-BASED PROGRAM FOR CHILDREN WITH CEREBRAL PALSY AND THEIR CAREGIVERS AND THE STAKEHOLDERS IN UGANDA.
REFNo: HS1979ES

1. To examine the impact of a community-based program on children with CP reported frequency of participation in the home, school, and community activities. 2. To assess the impact of a community-based training program on improving caregiver knowledge regarding CP and reducing caregiver stress. 3. To determine the impact of a communication and advocacy program in broadening stakeholders’ knowledge, attitude and practices regarding childhood disability and inclusion. 4. To determine the cost-effectiveness of a community-based program on children with CP, their caregivers, and the stakeholders in relation to costs and benefits.
Uganda 2023-04-20 21:15:22 2026-04-20 Medical and Health Sciences Clinical Trial Degree Award
Jedediah Silver
ID: UNCST-2023-R007939
The Effects of Cassava Drying Technology on Commercialization and Consumption Smoothing
REFNo: SS1700ES

The main goals of the pilot RCT are to ascertain the technical efficiency of the machines, the viability of the model where agents operate the machines and charge a fee for drying, and to observe how harvest and sales timing, consumption and cropping decisions change when farmers gain access to drying technology. In addition, we will explore additional mechanisms including varying the contract structure, and getting a sense of which channels are most salient to focus on (e.g. how likely we would be to detect effects on intertemporal smoothing beyond addressing the barriers to adoption to a seemingly profitable technology).
USA 2023-04-20 21:05:53 2026-04-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Beatrice  Onyango Ekesa
ID:
Bio-efficacy of Pro-Vitamin A-rich banana to improve vitamin A status among children in Uganda living in an area with a high burden of inflammation
REFNo: HS2721ES

3. Establish the stability of retinol isotopes on DSS at room temperature in the determination of TBS of vitamin A.,2. Assess the effect of inflammation and nutritional status on vitamin A absorption and TBS assessment among school-aged Ugandan children.,1. Determine the bio-efficacy of carotenoids in Pro-Vitamin A rich bananas in improving TBS in children aged 6-14years.,This study will determine the bio-efficacy of carotenoids in Pro-Vitamin A-rich banana-based diets and their potential in improving the vitamin A body stores by the RID technique among school-going children aged 6-14years living in Tororo district, an area with a high burden of inflammation.,
Kenya 2023-04-19 12:44:24 2026-04-19 Medical and Health Sciences Clinical Trial Non-degree Award
Bernard Muhangi Wakabi
ID:
Managerial competences and performance of Microfinance Institutions in Uganda
REFNo: SS1693ES

iii. To establish the moderating effect of stakeholder management on the relationship between managerial competencies and financial performance of MFIs in Uganda.,ii. To examine the mediating effect of competitive advantage in the relationship between managerial competencies and financial performance of MFIs in Uganda.,i. To examine the relationship between managerial competencies and financial performance of MFIs in Uganda.,The study will examine the relationship between managerial competencies and financial performance while examining the mediating effect of competitive advantage and stakeholder management's moderating effect in the relationship between managerial competencies and financial performance of MFIs in Uganda.,
Uganda 2023-04-19 12:41:29 2026-04-19 Social Science and Humanities Non-Clinical Trial Degree Award
Violet  Gwokyalya
ID: UNCST-2022-R010490
An Evaluation Study of Oral PrEP Delivery Models in Uganda
REFNo: HS2734ES

Primary Objectives 1. To document Oral PrEP delivery models currently in use in Uganda. 2. To establish the contribution of the various Oral PrEP delivery models to uptake of PrEP. 3. To establish the contribution of the various Oral PrEP delivery models to continuity of PrEP. 4. To establish the costs involved in implementing different PrEP delivery models in Uganda. 5. To document the best practices from the different PrEP Delivery models and the recommendations for promoting efficient and sustainable PrEP services. Secondary objective. To establish the feasibility of injectable PrEP delivery in Uganda
Uganda 2023-04-19 12:27:39 2026-04-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rosalind  Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
A pilot etiological study of genital ulcer disease in Uganda, including the burden of macrolide resistant T pallidum
REFNo: HS2728ES

-To determine the proportion of genital ulcers caused by syphilis compared with other causes of genital ulcer disease in a contemporary Ugandan setting.
-To determine the proportion of T pal isolates with evidence of macrolide resistance markers.
-To determine agreement between clinical diagnosis and treatment compared with laboratory diagnosis of GUD.
-To determine agreement between GUD PCR result and serological markers of infection including POCT and lab-based assays.
-To develop a library of GUD pictures stratified by microbiological diagnosis.


UK 2023-04-19 12:17:44 2026-04-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
GODFREY TUMUHAISE
ID:
Rapid Assessment of Avoidable blindness /Disability in the Northern, Eastern and Western Regions of Uganda in people aged 50 Years and above
REFNo: SS1695ES

• To determine the causes of blindness and VI.,• To explore the relationship between disability and socio-economic status and eye health,To determine the prevalence of disability among the study population. ,• To assess factors affecting access to cataract surgical services by determining cataract surgical coverage.,• To determine the prevalence and distribution of blindness and VI in the study population.,To estimate the prevalence and causes of blindness and visual impairment among people aged ≥50 years in Uganda.,
Uganda 2023-04-19 12:14:06 2026-04-19 Social Science and Humanities Non-degree Award
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