Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Investigation of mpox transmission, disease sequel, and molecular epidemiology in Uganda (Mpoxep)
REFNo: HS5387ES

Primary Objectives
1. To characterize the socio-demographic, clinical, immunological, and virologic epidemiology of Mpox cases in Uganda.
2. To describe the natural history and asymptomatic transmission dynamics of Mpox among contacts.
3. To assess risk factors for clinical hospitalization, ICU admission, and fatal Mpox outcomes.
4. To investigate long-term sequelae among Mpox survivors.

Secondary Objectives
1. To determine the incidence and prevalence of Mpox among high-risk populations (long-distance truck drivers, commercial sex workers, refugees, and PLHA).
2. To assess infection risk and asymptomatic transmission using serology among contacts.
3. To identify risk factors for infection among ‘de novo’ cases with no documented epidemiological link.
4. To explore socio-anthropological factors influencing Mpox transmission, prevention, and care-seeking behavior.
5. To identify potential animal reservoirs of MPXV in Uganda.
6. To describe histopathologic features of Mpox skin lesions and localization of MPXV in different body organs and tissues.

 Uganda 2024-12-23 10:56:56 2027-12-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Wycliff Odude
ID: UNCST-2024-R002431
 Small-scale field evaluation of the efficacy, residual activity and acceptability of Sovrenta® 15WP against Malaria Vectors in Adjumani district, West Nile, Uganda.
REFNo: HS5300ES

1. To determine the susceptibility levels of both wild-type and Kisumu strain malaria vectors to Sovrenta® 15WP insecticide in Adjumani District, West Nile, Uganda.
2. To determine the comparative residual activity of Sovrenta® 15WP and Actellic 300CS insecticides on common wall-type surfaces in Adjumani, West Nile, Uganda over 10 months.
3. To generate specific information related to the acceptability of Sovrenta® 15WP insecticide as a new product by the community in Adjumani, West Nile, Uganda.
4. To assess the ease of use of the Sovrenta by the spray operators under field conditions in Adjumani District, West Nile, Uganda.

Uganda 2024-12-10 16:05:33 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Roy Mayega William
ID: UNCST-2022-R010983
 Africa Regional Education System Resilience Observatory (ARESRO) Study - A Case Study of Uganda
REFNo: SS3453ES

General objective
To contribute to the improvement of the education system resilience in Uganda through evidence-informed programming.
Specific objectives
1) To explore the meanings and practices of education system resilience in Uganda
2) To explore the potential impact of future shocks and stressors, risk, vulnerability, and capacities (absorptive, adaptive, and transformative) on the future education ecosystems and outcomes in Uganda
3) To identify effective approaches and planning to address the future shocks and stressors, risks, vulnerabilities, and capacity for better education system resilience in Uganda

 Uganda 2024-12-10 16:04:12 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
ALEX ARIO RIOLEXUS
ID: UNCST-2024-R002455
 DEATHS AND INFECTIONS AVERTED, A COST - EFFECTIVENESS ANALYSIS AND FACTORS THAT INFLUENCE ADOPTION AND IMPLEMENTATION OF THE 7-1-7 TARGETS IN UGANDA: A case study of three Priority diseases
REFNo: HS5278ES

1.To estimate the number of deaths and cases from prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) averted if 7-1-7 targets are met in Uganda
2.To conduct a cost-effectiveness analysis for Uganda’s Ministry of Health implementing the 7-1-7 framework in responding to prioritized diseases (EVD, anthrax, Measles and Rift Valley fever disease) using societal perspective.
3.To explore and profile the factors that influence the adoption and implementation of 7-1-7 targets among different stakeholders in Uganda
 Uganda 2024-12-10 16:02:45 2027-12-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Violet Nkwanzi
ID: UNCST-2024-R002493
 Examining the Impact of Adverse Childhood Experiences on Human Trafficking Vulnerability and the Long-term Mental Health Outcomes of Women Survivors of Trafficking (18-35 years) in Uganda.
REFNo: SS3451ES

Aim 1: To quantitatively examine the association between ACEs, human trafficking vulnerability, and long-term mental health outcomes (anxiety, depression, PTSD). Aim 2: To determine the factors that moderate the effects of ACEs on human trafficking vulnerability and the long-term mental health outcomes of women survivors of trafficking. Aim 3: To qualitatively explore sources of resilience and gaps in existing policies and services for women affected by human trafficking in Uganda To inform comprehensive survivor centered interventions, this study will collect additional data on quality of life, gender-based violence, substance use and financial capability of survivors of trafficking.
Uganda 2024-12-10 16:01:57 2027-12-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
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