Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Juliet Babirye Ndimwibo
ID:
TREAT INTERACT: Implementing a user involved education- and health system interactive task-shifting approach for child mental health promotion in Uganda
REFNo: HS3144ES

Based on findings from objectives 1-2, develop implementation advice to guide policymakers in school-based child and adolescent mental health (CAMH) management, integration with the health system, and how to implement and sustain large-scale evidence-informed CAMH interventions to contribute towards achieving universal mental health coverage. ,Develop, implement and evaluate an intersectoral supervision, referral and communication model between the health and education sector.,Implement the adapted module-based TREATment mhGAP school program and investigate effective implementation strategies and client outcomes.,Intervention mapping to adapt the mhGAP-IG to a primary school setting, and implementation mapping to develop implementation strategies with user involvement,The main objective of the TREAT INTERACT study is to adapt, implement and evaluate the impact of an adapted school version of the mhGAP-IG that aims to prevent, identify, refer and treat mental health problems in children and adolescents in Uganda through a user involved task-shifting implementation of the mhGAP-IG among primary school staff. This work is divided into 4 work Packages (WPs); each of the specific objectives below represents a single work package.,
 Uganda 2024-02-02 12:05:35 2027-02-02 Medical and Health Sciences Clinical Trial Non-degree Award
Kamusiime B.  Samuel
ID:
PUBLIC PENSION SCHEME PROVISIONS AND PERCEIVED FINANCIAL WELLBEING OF RETIRING TEACHERS IN UGANDA: A CASE OF WAKISO DISTRICT GOVERNMENT AIDED PRIMARY SCHOOLS
REFNo: SS2244ES

i) To assess the relationship between the public pension scheme provisions and their implementation process on the financial wellbeing of retiring primary school teachers in Wakiso district.
ii) To examine the effect of the public pension scheme implementation process and the readiness to change jobs on the financial wellbeing of retiring primary school teachers in Wakiso district.
iii) To assess the effect of the readiness to change jobs on the financial wellbeing of retiring primary school teachers in Wakiso district.
iv) To assess the contribution of the public pension scheme provisions on the financial wellbeing of retiring primary school teachers in Wakiso district.

Uganda 2024-02-02 11:53:49 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Uptake of HPV Vaccination among female adolescents living with HIV/AIDS attending Mityana Hospital ART clinic
REFNo: HS3686ES

 To determine the prevalence and factors associated with HPV vaccination among young female adolescents living with HIV/AIDS at the Mityana Hospital ART clinic
 To assess the facilitators and barriers to HPV vaccine uptake in young female adolescents living with HIV/AIDS at the Mityana Hospital ART clinic using the COM B model.
 To Identify key behaviors that can improve uptake of HPV vaccination among young female adolescents living with HIV/AIDS through workshops using COM Bmodel

 Uganda 2024-02-02 11:51:02 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Naris Ninsiima
ID: UNCST-2023-R006134
 ENHANCING STAKEHOLDER PARTICIPATION FOR EFFECTIVE MANAGEMENT OF PUBLIC MARKETS IN URBAN AREAS: A CASE OF KABALE AND MBARARA CENTRAL MARKETS
REFNo: SS2314ES

To evaluate the level of stakeholder participation on management decision making in Kabale and Mbarara Central Markets.,To determine the level of stakeholder participation on policy development in Kabale and Mbarara Central Markets,Assess the levels of stakeholder participation on planning in Mbarara and Kabale Central Markets ,To explore significant avenues of stakeholder participation in Kabale and Mbarara Central Markets. ,The general objective to investigate the effect of stakeholder participation in the effective management of Kabale and Mbarara Central Markets. ,
 Uganda 2024-02-02 11:38:55 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Tadeo   Nsubuga
ID: UNCST-2023-R007982
 Evaluation of the deployment of the call for life (C4L) system among patients diagnosed with Tuberculosis in the Karamoja Sub-region North Eastern Uganda: A mixed-methods study.
REFNo: HS3431ES

1) To compare treatment outcomes among TB patients that utilised call for life (C4L) services and those who did not utilise the services in Karamoja subregion.

2) To understand the barriers and facilitators for utilization of C4L among TB patients that received CallforLife technology services in Karamoja region.
 Uganda 2024-02-02 11:34:18 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Komuhangi
ID:
IMPACT OF EDUCATIONAL INTERVENTION ON BREAST SELF EXAMINTAION AS A SCREENING STRATEGY FOR BREAST CANCER AMONG UNIVERSITY FEMALE STUDENTS IN UGANDA
REFNo: HS3762ES

(iv) To evaluate the relationship between knowledge level and social demographic variables.,(iii) To determine post-test knowledge, attitude, and skill of practicing SBE among female university students.,(ii) To equip knowledge and promote the skills of practicing SBE through an education intervention among female university students.,(i) To assess the pre-test knowledge, attitude, and skill of practicing SBE among female university students in Uganda.,The main objective is to assess the impact of educational intervention on Self- Breast Examination (BSE) as a screening strategy for breast cancer to promote health knowledge and practice of BSE among female university students in Uganda.,
 Uganda 2024-02-02 11:26:29 2027-02-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Aggrey Semeere Semwendero
ID: UNCST-2019-R001648
 EVALUATION OF THE USE OF TELEDERMATOLOGY AMONG PRIMARY CARE PATIENTS IN KAMPALA
REFNo: HS3655ES

Aim 3: Define the distribution of dermatologic diagnoses that arise in primary care settings in which TD is used and their subsequent management. ,Aim 2: Evaluate the barriers and facilitators to implementation of the TD service,Aim 1: Describe the utilization of TD in ambulatory care settings. ,
 Uganda 2024-02-02 11:24:53 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SIYA AGGREY
ID: UNCST-2019-R001737
 VALUES OF BATS TO ECOSYSTEM AND HUMAN COMMUNITIES: IMPLICATIONS FOR THEIR CONSERVATION AND PUBLIC HEALTH AROUND MOUNT ELGON ECOSYSTEM, UGANDA
REFNo: NS718ES

General objective To contribute knowledge relevant in advancing surveillance for One Health-related challenges in Mount Elgon Ecosystem, contributing to improved bat conservation as well as optimal human health. Specific objectives 1. To assess the socioeconomic values of bats in the Mount Elgon ecosystem, Uganda 2. To assess the socioeconomic values of caves in the Mount Elgon ecosystem, Uganda 3. To assess the vulnerability of bat roosts to anthropogenic cave disturbance in the Mount Elgon ecosystem, Uganda 4. To assess the capacities of communities in undertaking disease surveillance tasks for One Health issues
Uganda 2024-02-02 11:21:03 2027-02-02 Natural Sciences Non-Clinical Trial Degree Award
Kawooya  Jimmy
ID:
THE IMPACT OF WELFARE SERVICES ON TEACHER’S PERFORMANCE IN PRIVATE SENIOR SECONDARY SCHOOLS IN WAKISO DISTRICT, UGANDA
REFNo: SS2259ES

(i) To scrutinize the impact of monetary allowances on teachers' performance in private secondary schools in Wakiso District
(ii) To determine the effect of guidance and counselling services on teachers' performance in private secondary schools in Wakiso District
(iii) To investigate the impact of training and development on teachers' performance in private
secondary schools in Wakiso District
(iv) To analyze the influence of housing on teachers' performance in private secondary schools in Wakiso District
(v) To determine the impact of staff flextime on teachers' performance in private secondary schools in Wakiso District
 Uganda 2024-02-02 11:19:54 2027-02-02 Social Science and Humanities Non-Clinical Trial Degree Award
Michael  Baganizi
ID: UNCST-2023-R006352
 Rapid human centred design to develop, test and evaluate a job aid prototype for frontline immunization healthcare workers in Uganda
REFNo: HS3667ES

Needs Assessment 1. To assess the frontline immunization healthcare workers’ perceptions, practices and implementation of procedures using the current job aids. a. How well healthcare workers believe the available job aids support them to perform immunization processes or procedures b. How well supervisors believe the available job aids support their staff to perform immunization processes or procedures 2. To identify processes and procedures that may require a job aid versus another approach to improve HCW performance. Human Centered Design Workshops: 1. To prioritize the problem(s) (as identified through the needs assessment) that need to be addressed with job aid(s) with immunization HCWs and supervisors 2. To design practical, useful job aid prototype(s) around 2YL and catch-up immunizations with immunization HCWs and supervisors. ,1. To assess the uses, preferences and technical requirements of current and future 2YL immunization job aids, with the goal of identifying the knowledge gaps for administering the second dose of measles-containing-vaccine -second dose (MCV2) post introduction, including routine and catch-up vaccine job aids. 2. To design, test, and evaluate a prototype for MCV2 and catch-up immunization job aids with healthcare workers using the HCD methodology.,
 Uganda 2024-02-02 11:15:09 2027-02-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eloise Pedersen
ID:
The effect of payoff and rank on chimpanzee foraging decisions
REFNo: NS724ES

Objective 1: To determine the presence or absence of a preference towards a. high payoff behavioral techniques and b. model rank in chimpanzees. Objective 2: To examine the impact of individual differences on transmission bias preference in chimpanzees.
 UK 2024-02-02 11:12:23 2027-02-02 Natural Sciences Non-Clinical Trial Degree Award
Karugahe Wilber
ID: UNCST-2023-R005686
 Exploring the mental health needs of orphans and vulnerable children in Nakivale Refugee Settlement, Uganda
REFNo: SS2264ES

• To understand the experiences, needs and views on mental health issues of OVCs and their carers
• To explore factors related to their participation in research

 Uganda 2024-01-31 11:19:28 2027-01-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Tuhairwe
ID: UNCST-2023-R007692
 KNOWLEDGE AND ATTITUDE OF UNIVERSITY STUDENTS TOWARDS THE USE OF TELEMEDICINE TO ACCESS SEXUAL AND REPRODUCTIVE HEALTH SERVICES: A CASE OF MBARARA UNIVERSITY OF SCIENCE AND TECHNOLOGY IN UGANDA (KAUSTER STUDY).
REFNo: HS3731ES

Broad objective
To determine the knowledge and attitude of undergraduate students at Mbarara University of Science and Technology (MUST) towards the use of telemedicine to access sexual and reproductive health services.
Specific objectives
i. To assess the knowledge of undergraduate students at MUST of the availability of telemedicine to access sexual and reproductive health services.
ii. To examine the attitudes of undergraduate students at MUST towards the use of telemedicine to access sexual and reproductive health services.
iii). To explore the determinants of knowledge and attitude of undergraduate students of MUST towards the use of telemedicine to access sexual and reproductive health services.
 Uganda 2024-01-29 15:22:43 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mia Appelbäck
ID:
Experiences of patients, caretakers and healthcare providers in the referral process for post-partum haemorrhage and other obstetric emergencies to Kawempe National Referral Hospital
REFNo: HS3589ES

Explore the women’s, their partners’ and/or other caretaker’s perception of the implications of the near-miss postpartum haemorrhage event, e.g., health and socioeconomic consequences.,Explore women’s, their partners’ and/or other caretaker’s experience of effective communication, respect and preservation of dignity and emotional support within the maternal healthcare and referral system,Map women’s journey, as well as influencing factors, through the healthcare and referral system from onset of labour to near-miss postpartum haemorrhage , through her, her partner’s and/or other caretaker’s perspective ,To better understand the women’s, their partners’ and/or other caretaker’s perspectives of near-miss postpartum haemorrhage event in the healthcare and referral system,Explore healthcare workers at Kawempe National Referral Hospital perceptions of challenges and facilitating factors when receiving referred obstetric emergencies.,Map the referral process from referring institute to national referral hospital as perceived by healthcare providers,Investigate what challenges and facilitating factors healthcare providers experience in the referral of obstetric emergencies to a higher-level institutions,Explore what factors affect decision-making in the referral of obstetric emergencies to a higher-level facility,To better understand the referral system for obstetric emergencies, primarily PPH, from healthcare providers´ perspectives. ,
 Sweden 2024-01-29 15:21:02 2027-01-29 Medical and Health Sciences Non-Clinical Trial Degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
 TARGET MALARIA UGANDA PROTOCOL B2- RESEARCH AND DEVELOPMENT: MAINTENANCE OF WILD TYPE An. gambiae COLONIES IN THE ARTHROPOD CONTAINMENT LEVEL 1 (ACL1) INSECTARY AND HANDLING METHODS OPTIMIZATION AND DEVELOPMENT STUDIES Version 1.0 2023
REFNo: NS694ES

1.To Maintain the wild-type Anopheles strains Ag(WT) in the Uganda ACL1 insectary.
2.To support research and development preparatory studies in the insectary.
3.Support to Field Entomology, Stakeholder Engagement Regulatory activities.
4.To develop Staff capacity in preparation for research and development.

 Uganda 2024-01-29 15:19:10 2027-01-29 Natural Sciences Non-Clinical Trial Non-degree Award
Japheth Kwiringira Nkiriyehe
ID: UNCST-2019-R000408
 What do beneficiaries in the agro sector value chain consider Significant Change from Women Economic Empowerment?
REFNo: SS2141ES

Main Objective
What do beneficiaries of Women Economic Empowerment (WEE) consider significant in their lives?
Specific objective
i) To establish firsthand contextual accounts of what beneficiaries consider WEE to be.
ii) To explore what WEE beneficiaries consider as significant in their life.
iii) To identify ways to improve women economic empowerment interventions

 Uganda 2024-01-29 15:15:11 2027-01-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Engineer  Bainomugisha
ID: UNCST-2023-R005928
 AirQount: Autonomous vehicle emissions estimation system for low-resource cities
REFNo: SIR277ES

1. Design and build custom hardware for vehicle image capturing system for traffic data collection for training machine learning (ML) models
2. To collect traffic and vehicle data, curate and label the video streams and images resulting in usable datasets for training the AI models
3. Build a machine learning (ML) and computer vision-based system for vehicle recognition and classification that can be linked at available databases on vehicle estimation per vehicle.
4. To build a prototype software system that integrates the hardware and AI models for demonstration of the automated traffic emission estimation system
5. To pilot the developed software and hardware systems and assess their use in vehicle emissions understanding
 Uganda 2024-01-29 15:11:28 2027-01-29 Engineering and Technology Non-Clinical Trial Non-degree Award
Namajja Ketty
ID:
Quality assurance and quality control for ethical practice in clinical research conducted in southwestern Uganda
REFNo: SS2263ES

To assess the quality assurance measures employed in clinical research in Southwestern Uganda. To establish quality control procedures used by clinical researchers in Southwestern Uganda. To determine the level of adherence and factors influencing adherence to ethical practices among clinical researchers of Southwestern Uganda
 Uganda 2024-01-29 15:09:58 2027-01-29 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Discrete choice experiment to guide HIV prevention counseling with novel HIV prevention products
REFNo: HS3665ES

To determine preferences for attributes of HIV prevention counseling that would support young women in Uganda to initiate and sustain use of a PrEP product.
 Uganda 2024-01-29 14:58:57 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jacob Negrey Douglas
ID:
Multisystem aging patterns in chimpanzees (Pan troglodytes schweinfurthii) living at Ngogo, Kibale National Park, Uganda
REFNo: NS727ES

To better understand the biological and ecological forces that shape primate aging, we will assess both longitudinal and cross-sectional, age-related patterns of social, physiological, and physical variation in adult chimpanzees of the notably long-lived groups at Ngogo, Kibale National Park, Uganda. This project will integrate behavioral, genetic, endocrinological, immunological, and microbial data collected from wild chimpanzees. We will combine tried-and-tried observational and laboratory analyses with innovative, noninvasive omics-based approaches to studying physiological function. The proposed research will elucidate the advantages and limitations of wild chimpanzees as models of human health and aging and build an extensive multisystem dataset for future comparative chimpanzee research. The three primary goals of this research are outlined below: 1) Characterize cross-sectional and longitudinal aging trajectories across functional domains. How do functional domains vary in the timing and rate of age-related decline? Do some systems (e.g., physical function, immune function) exhibit later onset and/or slower rates of decline than do others? 2) Determine the extent of sex biases in aging trajectories in Ngogo chimpanzees. Given that female chimpanzees at Ngogo have greater life expectancies at birth than do males [25], do female chimpanzees also show slower or delayed rates of aging across most / all functional domains? Are aging effects more pronounced in some functional domains than others, and if so, which domains show greater sex biases? 3) Develop methods to noninvasively study chimpanzee aging. Given that the study of wild chimpanzees is strictly noninvasive, we will continue to develop, validate, and implement new methods for studying aging across a range of functional domains. Notably, we will continue to refine the use of video recordings to measure walking speeds, which are an invaluable measure of physical function in humans and nonhuman primates alike [32, 33]. We will develop new urinary biomarkers for use in wild chimpanzee studies including biomarkers of neurodegeneration (e.g., Alzheimer’s-associated neuronal thread protein) and physical function (e.g., urinary pentosidine). Finally, we will validate and implement the study of genetic material from chimpanzee saliva samples, including bacterial and epigenetic information, by collecting and subsequently analyzing chimpanzee saliva samples onsite at Ngogo using transportable sequencing equipment (MinION Mk1C sequencer, Oxford Nanopore Technologies, Oxford, UK).
 USA 2024-01-29 14:57:37 2027-01-29 Natural Sciences Non-Clinical Trial Non-degree Award
joel lwasa njagala calls
ID: UNCST-2023-R006315
 ASSESSING THE IMPACT OF MEDICAL INTERNS ON HEALTHCARE DELIVERY AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: SS2306ES

1.To compare hospital metrics at Kawempe National Referral Hospital when medical interns were present and when they were absent.
2.To compare patient outcomes at Kawempe National Referral Hospital when medical interns were present and when they were absent.
 Uganda 2024-01-29 14:56:29 2027-01-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jacqueline Kanywa Balungi
ID:
HPV Vaccine Survey: Determining reasons as to why girls have or have not received the HPV vaccine who attend the clinic at the Baylor Uganda center of excellence.
REFNo: HS3620ES

Primary objective:
To determine reasons as to why 10- to 18-year-old girls receiving health care services at the Baylor Uganda center of excellence have or have not received the HPV vaccine using a short survey during a study period of September 1, 2023 to December 31, 2023.

Long-term goal: To use the responses of this survey to develop educational and clinical counseling programs for increasing the uptake of the HPV vaccine among 9–13-year-old girls at the Baylor Uganda clinical center of excellence.

 Uganda 2024-01-29 14:03:23 2027-01-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hillary Kuteesa
ID:
PROFILES, REFERRAL PATHWAYS AND REASONS FOR REFERRAL FOR PATIENTS ADMITTED TO BUTABIKA NATIONAL REFERRAL MENTAL HOSPITAL.
REFNo: HS3412ES

1. To describe the socio-demographic characteristics of patients admitted to BNRH
2. To describe the referral pathways of patients admitted to BNRH
3. To describe the reasons for referral to BNRH

 Uganda 2024-01-25 18:41:36 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Nabirye
ID:
Hand hygiene interventions in Kampala's informal settlements: public health imaginaries local health realities.
REFNo: SS2188ES

1. To trace and characterise the framing of hand hygiene messaging by public health actors in Uganda since 1980.
2. To explore and describe the factors that maintain the preference for hand hygiene messaging among public health actors in Uganda.
3. To understand and compare the lived experiences informal settlement residents with the factors that maintain the preference for hand hygiene messaging by public health actors.

 Uganda 2024-01-25 18:40:37 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Juliet Kyayesimira
ID:
Development of Governor’s Plum (Flacourtia indica) Herbal Formulation for the Management of Microbial Infections in Humans
REFNo: NS661ES

4. To determine the appropriate propagation method and conditions for domestication and conservation of F. indica,3. To evaluate the efficacy of formulated prototypes Flacourtia indica extracts for the management of microbial infections,2. To quantify the major phytochemicals of medicinal value in methanolic extracts of F. indica,1. To assess the indigenous uses, genetic diversity and habitat range of Flacourtia Spp. in Uganda,
 Uganda 2024-01-25 18:38:49 2027-01-25 Natural Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Utility of a Liquid Biopsy in the Detection of Metastatic Breast Cancer in Uganda
REFNo: HS3277ES

To determine whether ctDNA can be used as a sensitive and specific measure of tumor burden and response to therapy among women with breast cancer undergoing treatment at UCI,To evaluate the feasibility, sensitivity, and specificity of the liquid biopsy, via ctDNA, to detect and quantify tumor-specific molecular characteristics in patients with metastatic breast cancer at UCI,
 Uganda 2024-01-25 18:37:59 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bosco Buruga Apparatus
ID:
Use of information and communication technologies by farmers to enhance the management of agricultural knowledge and information in West Nile Sub-Region of Uganda
REFNo: SS2084ES

Propose an ICT model for enhancing the management of agricultural and knowledge in developing countries using a case of West Nile sub-region, Uganda.,Identify the effects of challenges farmers face in the use of these ICTs for the management of agricultural knowledge.,Determine the challenges faced by farmers in the use of ICT in enhancing the management of agricultural knowledge.,Examine the factors influencing farmers in adopting and using ICTs for enhancing the management of agricultural knowledge in the West Nile sub-region, Uganda.,Find out agricultural stakeholders’ perception of the use of ICT in the management of agricultural knowledge.,Establish the status of managing agricultural knowledge management processes in the West Nile sub-region.,The purpose of the study is to investigate ways in which ICTs can be used to enhance the management of agricultural knowledge in West Nile sub-region of Uganda and to further propose a model to be adopted for enhancing access to agricultural knowledge by stakeholders. ,
 Uganda 2024-01-25 18:35:59 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Agnes Kabajuni
ID:
Researching Green Activism: How to better protect minority and indigenous communities, Civil Society Organisations, Networks, and climate Change Defenders in East Africa
REFNo: SS2032ES

Overall Objective: to create an enabling environment for climate change defenders from the ethnic minorities and indigenous peoples to play their role in pushing for responsive climate actions, hold governments accountable and protection of communities adversely affected by climate change impacts in Kenya, Tanzania and Uganda
Specific Objectives: a) Generate knowledge by collecting evidence that leads to a deeper understanding of key stakeholders of the challenges faced by environmental activists from the ethnic and indigenous minorities and traditional knowledge as climate change mitigation strategies.
b) Equip environmental activists from MIPs with knowledge/ideas on how to develop successful strategies to mitigate the challenges they face as part of their work and how to meaningfully blend gender and social inclusion in their work.
c) Promote greater collaboration, cross exchange and learning between duty bearers, civil society movements for inclusive decision-making processes.

Uganda 2024-01-25 18:32:52 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Field Pilot Study for Histoplasmosis and Aspergillosis testing among patients with Advanced HIV Disease in Uganda.
REFNo: HS2803ES

To determine the integration needs of the Clarus Histoplasma Galactomannan Enzyme Immuno Assay (HGM201) and Sōna Aspergillus Galactomannan Lateral Flow Assay (AGM LFA) in the routine screening, testing and management processes for AHD patients in Uganda. To assess the operational characteristics such as usability and acceptability of the Sōna Aspergillus Galactomannan Lateral Flow Assay (AGM LFA) in the public health context. To assess the operational characteristics such as usability and acceptability of the Clarus Histoplasma Galactomannan Enzyme Immuno Assay (HGM201) in the public health context. To determine the prevalence of invasive aspergillosis in Advanced HIV Disease patients in Uganda. To determine the prevalence of disseminated histoplasmosis in Advanced HIV Disease patients in Uganda.
 Uganda 2024-01-25 18:23:34 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
 Point of Care (POC) based Interventions to Improve sexual partner testing and tracking for Chlamydia Trachomatis (CT) and Neisseria Gonorrhoea (NG) in Kampala metropolitan STD clinics (POC-PIKAM STUDY)
REFNo: HS1448ES

To estimate the prevalence of commonly occurring causal organisms for genital discharge in men and women (N. gonorrhea and C. trachomatis T. Vaginalis and Gardnerella) infections in men and women attending outpatient clinics in Kampala using molecular diagnostic tests (Xpert) and other point of care tests,To assess the feasibility and reliability of participant self-collection for POC CT/NG tests (Xpert and Binx io CT/NG tests) and evaluate accuracy of the Binx io CT/NG Test against clinician provider and the Laboratory gold standard among persons presenting with genital discharge attending outpatient clinics in Kampala metropolitan .,To describe the perceptions and practices of persons regarding self-collection and self-testing for STD, and STD partner notification among persons with genital discharge attending outpatient STD clinics in Kampala, Uganda.,To evaluate the use of self-collection and self-testing of swabs in increasing the proportion of individuals and partners that get tested and treated for STI among persons presenting with genital discharge attending outpatient clinics in Kampala, Uganda. ,Our overall goal is to evaluate the effect of an intervention that includes; self-collection and partner notification on the proportion of partners of persons with vaginal and urethral discharge who return to the clinic for partner follow up and treatment at outpatient clinics in Kampala district and on management of NG and CT in this population.,
 Uganda 2024-01-25 18:21:26 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET NABIRYE
ID: UNCST-2023-R006463
 Adoption, Compliance and Effectiveness of MOH-Recommended Biosafety Practices and Guidelines at Public Health Laboratories in Central Uganda: A Cross-Sectional Survey.
REFNo: HS3437ES

1. To evaluate the adoption and compliance of MoH recommended biosafety practices and guidelines at PHLs in Central Uganda

2. To evaluate the effectiveness of MoH recommended biosafety practices and guidelines at Public Health Laboratories (PHLs) in Central Uganda

 Uganda 2024-01-25 18:19:01 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 Perceived Maternal Social Support and Perinatal Depression among women in Public health facilities, Mbarara district, south western Uganda (PEMPED)
REFNo: HS3525ES

Aim 1: To determine the prevalence of antepartum depression and its associated factors among pregnant women in latent labor in Mbarara district, south western Uganda

Aim 2: To determine the prevalence of maternity blues at six hours and six days postpartum and its associated factors among mothers in Mbarara district, south western Uganda

Aim 3: To examine the association between perceived maternal social support and postpartum depression among mothers in Mbarara district, south western Uganda

Aim 4: To explore perceived psychosocial support practices, types and preferences by postpartum mothers in Mbarara district, south western Uganda

 Uganda 2024-01-25 18:14:54 2027-01-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Fanny Fauli Laessoee
ID:
Agrarian Change – How traditional agricultural knowledge and narratives of the future influence agricultural adaptation to climate change amongst smallholders in Acholiland, Northern Uganda
REFNo: A383ES

3. To explore how narratives of the future influence changing agricultural practices, 2. To examine the role of Traditional Agricultural Knowledge in agrarian change, 1. To identify how small-scale farming practices have changed over time Overall research objective: How are traditional agricultural knowledge and Narratives of the future influencing agricultural adaptation to climate change amongst smallholders in Acholiland, Northern Uganda? ,
 Denmark 2024-01-25 18:13:00 2027-01-25 Agricultural Sciences Non-Clinical Trial Degree Award
Kamada Lwere
ID: UNCST-2022-R009359
 THE RECRUITMENT AND RETENTION OF ALZHEIMER’S DISEASE DIVERSITY GENETIC COHORTS IN THE ALZHEIMER’S DISEASE SEQUENCING PROJECT(READD-ADSP)
REFNo: HS3097ES

Perform genomic analyses,Management of all phenotype, genomic and biomarker data. ,Process, store, and assay biomaterials for the genomics resource including DNA isolation, plasma, and RNA for future gene expression studies,Adjudication and Harmonization of clinical and neurocognitive data,Develop a large genomics resource for the study of AD in individuals with AF and HL ancestry,The overall goal of this proposal is to build a resource that greatly expands the presentation of currently underrepresented African ancestry (African American (AA) and Africans (AF)) and Hispanic/Latinx (HL) individuals in AD genetic studies.,
 Uganda 2024-01-25 18:00:36 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Feasibility Assessment of a Comprehensive Treatment Approach for Advanced Breast Cancer using Innovative Cancer Medicines in a Low Resource Setting in Uganda.
REFNo: HS3006ES

a. Primary objectives
The primary objectives of the study are to:

I. To measure the number of patients, out of those who are eligible, who are willing to begin immunotherapy within the recruitment period if perceived barriers are removed
II. To determine the proportion of patients who drop out over the duration of the study period

b. Secondary objectives
I. To describe the incidence of adverse events in patients on immunotherapies
II. To elucidate reasons for discontinuation of patients on immunotherapy treatment
III. To determine the factors associated with the acceptability of patients and healthcare workers for immunotherapy
IV. To describe the quality of life of breast cancer patients on immunotherapy

Uganda 2024-01-25 17:55:55 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JAMES  KAYIMA
ID:
The development and testing of a low-cost mHealth intervention to improve blood pressure control in Uganda
REFNo: HS3060ES

1) To assess the level of BP control among ambulatory patients attending the hypertension clinic at Kiruddu National Referral Hospital.
2) To explore the perspectives of patients and providers on the acceptability of a mHealth (mobile app) and enhanced self-care strategy and elicit preferred features of a mHealth strategy for BP control.
3) To develop a mobile app for low-cost phones applying a user-centered design process among patients and providers at Kiruddu National Referral Hospital for control of blood pressure.
4) To assess the feasibility of using the m-health app among patients, community health care workers, and clinicians in Kiruddu National Referral Hospital, focusing on acceptability, practicality, demand, adaptation, and pilot the efficacy of the intervention on BP control.

 Uganda 2024-01-25 17:52:25 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edward Mokooza Kibikyo
ID: UNCST-2020-R014923
 PREVALENCE AND DETERMINANTS OF SUBSTANCE USE AMONG UNDERGRADUATE STUDENTS AT THE UGANDA CHRISTIAN UNIVERSITY
REFNo: HS3577ES

1. To describe the current model of substance use care and assistance for UCU students.

2. To measure the point prevalence of substance use among undergraduate students at UCU main campus in the January/May semester of 2024.

3. To determine the effect of faith (knowing), religion (doing) and spirituality (Being) on substance use among UCU students

 Uganda 2024-01-25 17:43:59 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
 A CASE STUDY EXPLORING THE VALUE CHAIN, ENABLERS, OBSTACLES, AND BUSINESS MODELS TO SUSTAIN PRIVATE DIGITAL HEALTH BUSINESS ON GLOBAL GOODS IN UGANDA: A MIXED METHODS CONCURRENT TRIANGULATION STUDY DESIGN
REFNo: SS2051ES

To explore parts of the value chain the companies dealing in digital health are active in and global goods worked with.,To assess barriers(obstacles), enablers for running a private business on digital global goods,To explore business models used to sustain digital health business among the two companies.,i. To explore business models used to sustain digital health business, enablers and barriers to running a private business on digital global goods in Uganda..,
 Uganda 2024-01-25 17:40:26 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
ASIIMIRE  DONATH
ID: UNCST-2021-R013270
 Male-Led health Promotion Program
REFNo: SS2254ES

To develop questions to inform the development and implementation of the male-led group health promotion program for African refugee men,To collect data from African refugee men, women, and other stakeholders around their understanding of the health education needs, concerns,To develop a Male-Led health Promotion Program” for African Refugee men living in Nakivale Refugee Settlement Camp ,
 Uganda 2024-01-25 17:39:17 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philippa Musoke
ID: UNCST-2021-R013523
 Using Implementation Science To Understand And Design Stakeholder Informed Innovative Interventions To Improve Youth HIV Prevention And Care Continuums In Rural And Urban Uganda
REFNo: HS3625ES

We will use platforms in aims 1 and 2 to strengthen capacity of implementation science and to translate findings into policy and guidelines through clearly defined and established channels. ,To assess the rollout of a culturally acceptable, feasible HIV prevention and care intervention among AYA at high risk, on uptake and persistence to CAB-LA or SEARCH-YOUTH treatment support intervention using implementation effectiveness hybrid designs. Aim 2 will be informed by Aim 1 with regards to specific implementation features. We will recruit AYA (15-24 years) both HIV negative and HIV positive. We will screen them for high risk of seroconversion if negative and for those testing HIV positive unsuppressed or at risk of being unsuppressed. We will assess scale up in real world settings of evidence-based interventions to increase uptake and persistence on CAB-LA (HIV negative) and increase viral suppression (HIV positive) among high risk AYA.,Using the updated CFIR, we will identify determinants (barriers and facilitators) of potential implementation success of two innovations: CAB-LA uptake and persistence and SEARCH-YOUTH (SY) implementation at the community, clinic, organization, provider, and patient levels in five CRPS in urban, semi-urban and rural Uganda. Using CFIR implementation science framework we will conduct in-depth key informant interviews and focus group discussions with five different stakeholder groups:,
 Uganda 2024-01-25 17:36:24 2027-01-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SCHOLASTICA TIGURYERA
ID:
Instructional leadership and teaching quality of academic staff mediated by self-efficacy in public universities in Uganda
REFNo: SS2245ES

i. Examine the influence of instructional leadership on teaching quality of academic staff in public universities in Uganda.
ii. Assess the influence of instructional leadership on self-efficacy of academic staff in public universities in Uganda.
iii. Examine the influence of self-efficacy of academic staff on teaching quality in public universities in Uganda.
iv. Test the mediating effect of teacher self-efficacy on the influence of instructional leadership on teaching quality of academic staff in public universities in Uganda.

 Uganda 2024-01-25 17:34:18 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Marion Ouma Atieno
ID:
Setting the Research Agenda on Sexual Reproductive Health and Rights (SRHR) and Women’s Economic Security and Inclusion (WESI) in East Africa
REFNo: SS2249ES

• To identify emerging and unresolved research gaps/questions on SRHR as well as women’s economic security and inclusion in East Africa, particularly Kenya and Uganda.,• To synthesize findings of previous research-agenda setting exercises on SRHR and women’s economic empowerment and inclusion in East Africa.,
 Kenya 2024-01-25 17:33:20 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
KASIRYE ANDREW KATO
ID: UNCST-2023-R008128
 The Founder's Charism and child safeguard in selected ARU Member institutions
REFNo: SS2308ES

a. To suggest and recommend to religious institutions the need of designing child safeguard policies by utilizing and basing on their founder’s charism.,
 Uganda 2024-01-25 17:31:27 2027-01-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Primah Namudiba Kwagala
ID:
GENDER AND THE LEGAL HISTORY OF ABORTION: THE LEGACY OF COLONIAL LEGISLATION IN UGANDA
REFNo: SS2247ES

The main objective of this study is to interrogate Uganda’s legal history on abortion and its legacy on contemporary laws regulating access to safe abortion services in Uganda. Specifically, the study has objectives to
1. Analyse gender dynamics that influenced regulation and means of abortion in pre-colonial Uganda
2. Examine the influence of colonialism on regulation of abortion practices for women in Uganda
3. Assess the legacy of colonial legislation on contemporary laws regulating access to safe abortion services in Uganda and;
4. Identify strategies to decolonize abortion laws in Uganda to inform legal and policy interventions on access to safe and legal abortion

 Uganda 2024-01-25 17:29:51 2027-01-25 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Tusubira Kuguminkiriza
ID: UNCST-2021-R014026
 Redefining selfcare among people living with HIV: perceptions and practices of HIV and co-morbidity in Uganda.
REFNo: HS3639ES

To understand how persons living with HIV and chronic comorbidities experience and interpret selfcare, in order to redefine selfcare in the Ugandan context.

Specific objectives:
1. To explore the self-care practices of persons living with HIV for managing hypertension or diabetes comorbidities in low-and-middle income countries.
2. To explore how people living with HIV with hypertension and/or diabetes, enrolled in care in Uganda, interpret looking after themselves and their health in their daily lives (selfcare).
3. To determine treatment and heath maintenance practices adopted by people living with HIV and hypertension and/or diabetes enrolled in care in Uganda.
4. To examine the capacity and support for self-care among persons living with HIV and hypertension and/or diabetes enrolled in care in Uganda.

 Uganda 2024-01-25 16:08:26 2027-01-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
 Evaluation of a multicomponent intervention to improve perinatal bereavement support for women and families after stillbirth and neonatal death in Kenya and Uganda: A pragmatic cluster randomised controlled trial.
REFNo: HS3205ES

To explore factors influencing future scale up and sustainability of the intervention ,To explore potential mechanisms of impact of the intervention through understanding womens’, families’, health workers’ and service managers’ views and experiences of the intervention and usual care after stillbirth and neonatal death,To evaluate whether the intervention was implemented as intended during the trial by assessing fidelity, ‘dose’, reach and adaptations made in the study context. ,To assess the cost effectiveness of the intervention from the perspective of the local health systems in Kenya and Uganda ,To assess the mediating effect of perceived social support on intervention impact. ,To assess the impact of the intervention on maternal anxiety, risk of depression and development, diagnosis, and treatment of mental health conditions.,To assess the effectiveness of the co-produced multicomponent interventions in reducing perinatal grief intensity at 8-12 weeks post birth for women who have experienced stillbirth or early neonatal death. ,
 Uganda 2024-01-24 23:23:30 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Nyantaro
ID: UNCST-2023-R006533
 Knowledge, Perceptions and Practices of Parents, Community Members and Health workers on Unclassified Sudden Infant Deaths in Uganda.
REFNo: HS3465ES

This study aims to assess the knowledge, perceptions and practices of parents, community members and health care workers on USIDS in the community in Uganda.
1. To determine the knowledge, perceptions and practices of parents and community members on unclassified sudden infant death syndrome in Uganda.
2. To determine the knowledge, perceptions and practices of health workers on unclassified sudden infant death syndrome in Uganda.
 Uganda 2024-01-24 23:17:54 2027-01-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Kisekka
ID:
SOIL MICROBIOTA-MEDIATED DISEASE TOLERANCE IN ROBUSTA COFFEE AGROFORESTRY SYSTEMS IN UGANDA
REFNo: NS709ES

To enhance the sustainability of robusta coffee agroforestry systems based on the optimization of plant microbiota interactions for improving coffee response to common diseases in Uganda. ,4. To determine the impact of drought on interactions among soil microbiota, coffee, and pathogens (greenhouse conditions).,3. To evaluate the effects of different soil microbiota composition (shade tree rhizosphere -derived) on the growth and tolerance of coffee trees to major diseases (greenhouse conditions).,2. To determine the extent of influence of shade trees on the soil microbiota associated with robusta coffee (field conditions). ,1. To characterize the soil microbial diversity associated with shade trees and coffee trees in robusta coffee agroforestry systems (field conditions).,
 Uganda 2024-01-24 23:15:17 2027-01-24 Natural Sciences Non-Clinical Trial Degree Award
Fatumo  Segun Adeyemi
ID:
A single-cell quantitative trait map for peripheral blood in the Ugandan population
REFNo: HS3105ES

The overarching aim of this work is to shed light on the mechanisms that genetic variation affects celltype specific gene expression in peripheral blood mononuclear cells (PBMCs) in the Ugandan population for the first time. The key objectives are: 1. Construct a cell-type specific molecular map of PBMCs in Ugandan population
2. Identification of dynamic allelic effects across PBMCs’ lineages
3. Elucidate causality of cell-type specific genetic variants for cardiometabolic traits and diseases in Uganda
population
 UK 2024-01-24 23:07:48 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Myocardial Fibrosis and Steatosis Burden and Region-Specific Predictors of Progression among ART-treated Women with HIV infection in sub-Saharan Africa (The MUTIMA study)
REFNo: HS3606ES

2. To quantify myocardial steatosis burden and identify hormonal/metabolic predictors of progression among ART-treated WWH in SSA,1. To characterize myocardial fibrosis burden and identify novel infectious/immunologic predictors of progression among ART-treated women with HIV in SSA. ,
 Uganda 2024-01-24 23:01:55 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arthur Bagonza
ID:
ASSESSING THE BURDEN AND UNDERSTANDING THE CONTEXT OF LYMPHOEDEMA IN UGANDA: A PREVALENCE STUDY AND SITUATION ANALYSIS
REFNo: HS3713ES

2. To conduct a stakeholder analysis in order to gather essential data for the development of effective lymphoedema treatment and care interventions at both primary and secondary healthcare levels in Buvuma and Napak districts of Uganda. ,1. To determine the prevalence of lymphoedema in Buvuma and Napak districts of Uganda,To determine the burden and context of lymphoedema in Uganda,
 Uganda 2024-01-24 22:55:44 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Household Energy Related Burns Study - Burden and Context Evaluation in Hospital Settings in Uganda (CLEAN-Air (Africa) HERBS)
REFNo: HS3614ES

1. To conduct a retrospective review of hospital records (up to 5 years) to determine the burden of household fuel-related burns and their short-term impacts on affected individuals in Uganda.

2. To conduct a survey to examine the occurrence , severity and determining the circumstances of hospital treated burns caused by household energy use in a study period of 24 months, using the WHO Burn Registry data collection form.

3. To conduct a qualitative study gaming health care workers on knowledge, attitudes and practices of burns care including data collection of burn-related cases

 Uganda 2024-01-24 22:50:16 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Kisaakye
ID:
Feasibility of Routine Screening for Sexual Violence Against Children in Humanitarian Contexts in Uganda
REFNo: SS2265ES

The goal of the study is to expand the access of children/adolescents experiencing sexual violence to comprehensive sexual violence services in refugee settings in Uganda. The study’s specific objective is to assess the feasibility of adapting and implementing a multi-faceted screening intervention to expand such access.
Uganda 2024-01-24 22:46:56 2027-01-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 Study of Genomic Integrity and Safety of Stem-Cell Gene Therapy in Cohorts in Africa.
REFNo: HS3660ES

The overall aim of this research is to establish safe and accessible gene therapies for sickle cell disease by comparing and contrasting cohorts in Africa to the data already obtained from the USA and UK thus establishing a more accurate authentic dataset. We hypothesise that patients with SCD may have elevated somatic mutation rates as compared to healthy non-SCD individuals and that the mutational processes driving the acquisition of these genetic lesions are varied from individual to individual.
 UK 2024-01-24 22:45:26 2027-01-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Ajilong
ID: UNCST-2022-R005889
 Assessing Vitamin D serum levels in HIV-positive adolescents 10-19 years with depression in Northern Uganda
REFNo: HS3454ES

To determine the burden of depression in HIV-positive adolescents at Gulu RRH,To assess for serum Vitamin D levels in HIV Positive adolescents 10-19 years with depressive symptoms in Gulu Regional Referral Hospital Methods,
 Uganda 2024-01-24 22:30:43 2027-01-24 Medical and Health Sciences Clinical Trial Non-degree Award
Mercy Kainobwisho Kyomugasho
ID:
AN ANALYSIS OF THE BARRIERS TO PROTECTION AND COMMERCIALIZATION OF TRADEMARK ASSETS BY SMES IN THE NON-ALCOHOLIC BEVERAGE MANUFACTURING S IN UGANDA.
REFNo: SS2153ES

specific objectives of the study are to;
i. To investigate the relationship between trademark protection, licensing, valuation, collaterisation and commercialisation by SMEs in the non- alcoholic beverages in the manufacturing sector.
ii. To identify the barriers to protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector.
iii. To examine the legal and institutional framework for protecting, licensing, valuation and collateralisation of trademarks in Uganda.
iv. To propose effective ways for enhancing the protection, licensing, valuation and collateralisation of trademarks by SMEs in the manufacturing sector in Uganda

 Uganda 2024-01-23 18:58:37 2027-01-23 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Rujumba Rujumba
ID: UNCST-2022-R011160
 Combining monthly dihydroartemisinin-piperaquine and azithromycin for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda: Post-Discharge Malaria Chemoprevention -PDMC-II (acceptability and feasibility sub-study)
REFNo: HS3669ES

2)Explore perspectives of health care providers and caregivers on the feasibility of implementing PDMC with DP + AZ in children diagnosed with severe anaemia in Malawi and Uganda and generate insights for successful integration and scalability of PDMC with DP+AZ in resource-limited settings.,1)To assess health care provider and caregiver acceptability of PDMC with DP + AZ in children with severe anaemia at Malawi, Kenya, and Uganda trial sites. ,To determine the acceptability and feasibility from the health provider and patient/guardian perspective of delivering or receiving dihydroartemisinin-piperaquine (DP) and azithromycin (AZ) for the post-discharge management of children with severe anaemia in Malawi, Kenya, and Uganda.,
 Uganda 2024-01-23 18:57:41 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Nabwowe -
ID:
ALLELE FREQUENCY DATABASE FOR 21 SHORT TANDEM REPEATS IN THE UGANDAN POPULATION
REFNo: NS716ES

To establish the Ugandan population Y-Chromosome haplotype frequency database,To develop Ugandan population specific 21 autosomal STR markers and Y- chromosome haplotype markers allele frequency data ,To determine population genetic homogeneity among the selected tribes in Uganda ,To determine the genetic diversity of the 21 STRs in a Ugandan population by calculating the forensic and paternity efficiency parameters ,
 Uganda 2024-01-23 18:56:08 2027-01-23 Natural Sciences Non-Clinical Trial Non-degree Award
MARY AJIKO MARGARET
ID:
Prevalence of Paediatric burn injuries Admitted to a hospital in Teso sub-region Eastern Uganda: lessons for prevention
REFNo: HS3484ES

The main objective of this study is to investigate the causes, characteristics, patterns, geographic determinants of paediatric burns and identifying the barriers and enablers to their prevention in a home. Specific Objective of the Study 1. To examine the typical patterns and causes of paediatric burn injuries leading to hospitalization. 2. To establish care givers’ understandings of the injury to their children, considering both injury determinants and preventive means. 3. To assess the effects of various characteristics of the living area on paediatric burn injuries. 4. To determine the enablers and barriers to the creation of safe environment, the implementation of safe practices and the use of products that control or prevent childhood burn injuries in the home.
Uganda 2024-01-23 16:58:07 2027-01-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Margaret Mangheni Najjingo
ID:
Women empowerment, normative influence and project outcomes in Central Uganda
REFNo: SS1942ES

To identify factors that influence women’s economic empowerment within farming communities.

To explore the community construction of femininities and how it influences women’s economic empowerment within agricultural project intervention areas.

To explore the community construction of masculinities and how it influence women’s economic empowerment within agricultural project intervention areas

To find out the factors that influence women’s economic empowerment and household food security within agricultural project intervention areas

 Uganda 2024-01-22 11:38:01 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 EFFECTIVENESS OF THE PARTNER-LED IMPLEMENTATION IN IMPROVING DIGITAL PAYMENT AND CAMPAIGN QUALITY DURING THE YELLOW FEVER CAMPAIGN IN UGANDA: AN EXPLORATORY STUDY
REFNo: SS2221ES

To determine gender norms and relations and their influence on health workers’ response to payment systems (cash vs mobile money) and how these affect the health workers’ performance and motivation in yellow fever vaccination campaigns,To explore the effect of implementing a partner-led digital payment system on the Motivation, Satisfaction, and performance of vaccination campaign health workers,To establish the vaccination coverage of yellow fever in different geographies (equity),To document partner-led implementation process of the Yellow Fever Mass Vaccination campaign,To assess the effectiveness of partner-led Yellow Fever campaign and its effect on digital health worker payments and campaign coverage in Uganda.,
 Uganda 2024-01-22 11:26:43 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 OUTCOMES OF PEDIATRIC PATIENTS DIAGNOSED BY MORPHOLOGY ALONE VERSUS FLOW CYTOMETRY PLUS MORPHOLOGY: A RETROSPECTIVE STUDY
REFNo: HS3352ES

To compare the treatment outcomes between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To determine the accuracy of diagnosis of acute leukemia between patients diagnosed with the help of flow cytometry with those diagnosed without the help of flow cytometry.,To assess the time to treatment initiation among patients diagnosed with the help of flow cytometry and those diagnosed without the help of flow cytometry,
 Uganda 2024-01-22 11:25:41 2027-01-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Using Video-Enhanced Teaching to Increase Maternal Participation in Neonatal Hospital Care
REFNo: SS2030ES

3. To evaluate by survey the perspectives of healthcare workers on their availability to devote to video-assisted maternal education in a neonatal hospital unit in Uganda.,2. To identify maternal and/or neonatal factors that impact the amount of time needed to train mothers to weigh their baby, assess for danger signs, and track feeds using video-assisted teaching.,1. To determine the mean nursing time required to train mothers to perform three specific tasks: (1) weigh their baby, (2) assess for danger signs, and (3) track feeds when facilitated by video-assisted teaching.,The purpose of this study is to evaluate a video that teaches mothers how to monitor their baby in a neonatal hospital unit in Uganda. This is with the goal of reducing the amount of time healthcare workers need to spend teaching mothers and ultimately improving the quality of care that sick and small newborns receive in the hospital. ,
 Uganda 2024-01-22 10:45:51 2027-01-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kebirungi
ID:
A QUALITATIVE STUDY ON THE CAUSES OF SLOW ADOPTION OF VIRTUAL REALITY IN MEDICAL EDUCATION IN KAMPALA, UGANDA
REFNo: SIR261ES

Primary objective: To assess the causes of slow adoption of VR in medical education in Kampala ,Uganda Secondary objectives: 1. To identify perceptions of medical students, interns, lecturers at Makerere School of Medicine, doctors and medical association leads in Kampala towards use of VR in medical education. 2.To assess the VR programming capacity in Kampala, Uganda 3 To identify key policy guidelines that would empower VR in Uganda.
Uganda 2024-01-11 13:14:59 2027-01-11 Engineering and Technology Non-Clinical Trial Non-degree Award
Nazarius Tumwesigye Mbona
ID: UNCST-2019-R000664
 Regulating alcohol packaging and supply to protect health in Sub-Saharan Africa: evidence from policy systems in Malawi and Uganda (RAPSSA study)
REFNo: HS3130ES

General objective
1. To identify how regulatory controls on alcohol production and distribution can be improved and effectively implemented in Sub-Saharan Africa to reduce the availability of cheap, single-use products and related harms
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.


Specific objectives

1. To identify the adoption and formulation of the bans, what mechanisms for implementation were proposed and put in place, how the bans were enforced in practice, as well as stakeholder and public perceptions of, and explanations for, intended and unintended consequences of the bans.
2. To explore contextual factors important for the transferability of findings to other Sub-Saharan countries, to inform alcohol policy development and implementation across the region.

 Uganda 2024-01-11 12:40:52 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
 Evaluation of the impact of the Public Justice System strengthening program on violence against women and children in Uganda
REFNo: SS1980ES

d) To measure change in the status of empowerment and protection of women and children against sexual and intimate partner violence including establishing the prevalence of violence against women and children. ,c) To assess change in the performance of the justice system in prevention and response to violence against women and children in Uganda, with a focus on the ability of the criminal justice processes to secure justice for victims of intimate partner violence and sexual violence against children, b) To explore changes in stakeholder confidence in the criminal justice system and the reliance of victims / survivors of intimate partner violence and child sexual violence on the criminal justice system for redress. ,a) To assess the coherence and relevance of IJM’s VAWC program including profiling changes in the legal landscape, framework and processes for handling cases of violence against women and children in Uganda,The general aim of the study is to evaluate how strengthening the public justice system to enforce law (supply side) and empowerment of sexual and intimate partner violence survivors to undertake justice (demand side) contribute towards the protection of children and women from sexual and intimate partner violence. The evaluation will be guided by the Organization for Economic Co-operation and Development (OECD) Development Assistance Committee (DAC) evaluation criteria of Relevance, Coherence, Effectiveness, Efficiency, Impact, and Sustainability to measure impact,
 Uganda 2024-01-11 12:39:14 2027-01-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
DENIS OKELLO
ID: UNCST-2023-R007227
 Profiling Medicinal Plants and the Corresponding Community Conservation Practices within Kigezi Region
REFNo: NS667ES

Assess the community conservation strategies for priority medicinal plants in Kanungu, Kisoro and Rubanda districts.,To assess the cultural practices in Kanungu, Kisoro and Rubanda districts to ensure sustainable utilization and knowledge transfer of the medicinal values of these plants.,To assess traditional knowledge practices regarding medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To identify and document medicinal plants used by communities in Kanungu, Kisoro and Rubanda districts.,To profile medicinal plants in Kanungu, Kisoro and Rubanda districts in Kigezi region and assess local community conservation practices,
 Uganda 2024-01-11 12:35:14 2027-01-11 Natural Sciences Non-Clinical Trial Non-degree Award
Richard Mayanja
ID: UNCST-2022-R009948
 Genetic Determinants of Kidney Function in Sub-Saharan Africa
REFNo: HS3372ES

The overall aim of this project is to identify the genetic determinants of chronic kidney disease in sub-Saharan Africa
 Uganda 2024-01-11 12:32:07 2027-01-11 Medical and Health Sciences Non-Clinical Trial Degree Award
John Mark Bwanika
ID:
BUILDING MACHINE LEARNING ALGORITHMS FOR PREDICTIVE MODELLING OF THE ABILITY TO PAY FOR PRE-EXPOSURE (PREP) SERVICES, A PILOT STUDY IN KAMPALA, UGANDA.
REFNo: HS3474ES

Primary objective:
To develop and deploy an artificial intelligence (AI) modelling technique for PrEP services market segmentation.
Secondary objectives:
(i) To use machine learning and artificial intelligence modelling to analyze, and profile sub-populations that are able to pay for PrEP in Kampala.
(ii) To identify the most likely favorable pricing for PrEP
(iii) To validate the variables identified as predictors for PrEP payment from dataset analyses through focus group discussions.
(iv) To test the validity and reciprocity of the developed AI model with similar datasets from other settings.

 Uganda 2024-01-11 12:31:29 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of Clinical Performance and Usability of the KHB HIV I/II Ab Rapid Test (Self-Test) in the hands of untrained users. "Clinical Performance Study Plan - CPSP nr. KHB-CPH 23-039"
REFNo: HS3531ES

The objective of this laymen study is to establish and to qualify the usability of the KHB HIV Self-Test for self-testing in a low and a high prevalence HIV setting in Uganda as described in TSS-1 part 3. In addition, the layperson’s interaction with the device in terms of effectiveness and efficiency, i.e. successful/unsuccessful completion and difficulty of the critical steps as per Instructions for Use will be assessed. ,
 Uganda 2024-01-11 12:30:09 2027-01-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Zubair Lukyamuzi
ID: UNCST-2021-R013107
 Feasibility and Acceptability of a Barbershop Based HIV Prevention Initiative Among Heterosexual Men in Kalangala Islands, Uganda: A Cluster Randomized Trial
REFNo: HS3430ES

1. To compare completion of self-initiated HIV testing between intervention and control groups
2. To evaluate the preliminary effectiveness of the intervention on change in behaviors associated with HIV acquisition
3. To compare interest in or use of HIV prevention services between intervention and control groups
4. To evaluate the preliminary effectiveness of the intervention on incident STIs
Uganda 2024-01-08 13:20:21 2027-01-08 Medical and Health Sciences Clinical Trial Non-degree Award
Tumuhimbise Jasper Mpiriirwe
ID:
HEAD TEACHERS’ LEADERSHIP PRACTICES AND FINANCIAL PERFORMANCE IN CHURCH OF UGANDA FOUNDED SECONDARY SCHOOLS IN NAMIREMBE DIOCESE
REFNo: SS2126ES

4. To explore the influence of head teachers’ stakeholder collaboration on financial performance in the Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,3. To analyze the influence head teacher’s team leadership practices on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese in Namirembe Diocese.,2. To assess the influence of head teachers’ values on financial performance in Church of Uganda Founded Secondary Schools in Namirembe Diocese. ,1. To examine the influence of head teachers’ vision on financial performance of Church of Uganda Founded Secondary Schools in Namirembe Diocese.,The general objective of the study is to examine the influence of head teachers’ leadership practices on financial performance of Church of Uganda Founded Secondary Schools (CFSs) in Namirembe Diocese. ,
 Uganda 2024-01-08 13:18:02 2027-01-08 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Feasibility of Nanopore Sequencing for Classification of Pediatric Malignancies in Low Resource Settings
REFNo: HS3397ES

Expand upon our adapted unbiased Nanopore sequencing classification platform while verifying the feasibility of classification of pediatric solid tumors using GEP. Hypothesis: Unbiased Nanopore sequencing can be implemented and can accurately classify pediatric cancer in low and middle income countries,Establish technical and human resources needed to carry out local, real-time sequencing on Nanopore platforms through optimizing existing supply chains in collaboration with Nanopore and establishing standardized virtual and in-person training of local research, laboratory, and information technology support.,Optimize and validate, within the context of use in low and middle income countries, the efficacy unbiased Nanopore sequencing platform for pediatric cancer classification after integrating a Cloud-based computational analysis pipeline. Hypothesis: Using a Cloud-based unbiased Nanopore sequencing approach, clinical laboratories in LMIC can perform sequencing with Cloud based analytical support, accurately classify pediatric cancer diagnosis and genomic subtypes.,To determine the feasibility of implementing and utilizing Nanopore sequencing for classification of pediatric malignancies, as determined by technical quality, data management, and classification accuracy.,
 Uganda 2024-01-08 13:16:49 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tonny Ssekamatte
ID: UNCST-2022-R010961
 Climate change health vulnerability and adaptation assessment (VAA) for sound management of climate change-related health risks in Uganda
REFNo: HS3168ES

6. To use evidence from objectives 1-5 to inform the development of a National Health Adaptation Plan (H-NAP) for effective mitigation, adaptation and response to climate change in the health sector.,5. To understand how monitoring and evaluation of mitigation, adaptation and response measures to climate-change related risks and impacts on the health sector in Uganda should be done,4. To explore what should be done to effectively mitigate, adapt and respond to climate change-related risks and impacts in the health sector in Uganda,3. To identify policies, programmes and adaptation mechanisms that should be prioritized to address current and projected health risks in the health sector in Uganda,2. To describe and quantify the potential impacts (present and future) of climate change on the health sector in Uganda,1. To describe and quantify climate-change related risks (present and future risks) on the health sector in Uganda,To conduct a national health climate change vulnerability and adaptation assessment to identify health risk factors and gaps for sound management of climate change-related health risks in Uganda,
 Uganda 2024-01-08 13:15:39 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Sanya Edwin
ID: UNCST-2023-R006836
 The Next Generation Vaccine Card: Innovative Technology to Improve Vaccine Equity in Kagando, a Rural Setting in Uganda
REFNo: HS3515ES

To implement and evaluate using cluster-randomised and pre/post intervention approaches, the ‘next generation digital vaccine card’ in Kagando Uganda I. Implement the digital vaccine card intervention in rural Uganda II. Evaluate the implementation process and effectiveness of the intervention III. Evaluate the impact of the intervention on equity at the individual and village levels. IV. Conduct an economic evaluation of the intervention.,To co-design and develop a ‘next generation digital vaccine card’ for childhood vaccinations I. Design and build a prototype digital vaccine card and registry II. Use iterative feedback to refine the digital vaccine card and registry III. Develop a Minimum Viable Product (MVP) that meets the desired stakeholder specifications,To evaluate the current routine childhood vaccination landscape in Kagando Uganda I. Assess baseline routine childhood immunisation data quality at the facility level using WHO standard indicators II. Assess equity in routine childhood immunisation coverage and timeliness using household survey data III. Collect and analyse qualitative data to understand current knowledge, attitudes, and practices of vulnerable populations from patient and provider perspectives.,To develop and evaluate a ‘digital vaccine card’ and registry that will facilitate the electronic collection of individual data at health facilities to allow improved monitoring of vaccine coverage and timeliness by both healthcare providers and parents/caregivers, in turn improving vaccine equity in rural Uganda. ,
 Uganda 2024-01-08 13:14:20 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hakim Sendagire
ID:
Clinical, Hematological and Biochemical predictors of outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study)
REFNo: HS2961ES

General Objective
To evaluate the clinical presentation, treatment, clinical chemistry, immune chemistry, hematology and other laboratory predictors of clinical outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak
Specific Objectives
1. To evaluate the clinical presentation of patients at the time of admission in the ETU and treatment offered during admission as predictors of outcome among Sudan EVD patients admitted in hospital during the 2022 Ugandan Ebola Outbreak (CHEBE Study).
2. To describe the clinical chemistry, immune chemistry, hematology and other laboratory predictors of outcome in patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study).
3. To determine the association between laboratory profiles, comorbidities and clinical outcomes among patients admitted with Sudan Ebola virus disease during the 2022 Uganda Ebola Outbreak (CHEBE Study).

 Uganda 2024-01-08 13:13:08 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elisa van Dongen Maria Angela
ID:
Belief-based poverty traps and the effects of material and psychological interventions: Evidence from a lab-in-the-field experiment in rural Uganda
REFNo: SS2137ES

This research aims to empirically study the effects of aid on beneficiaries' and non-beneficiaries' agency beliefs and effort decisions.
 Netherlands 2024-01-08 13:12:25 2027-01-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Building the Foundation for Effective Sore Throat Treatment in Uganda.
REFNo: HS3473ES

Objective 1: Co-design a sore throat treatment program model using a community based participatory research approach to ensure a culturally and contextually appropriate and effective strategy for primary prevention of RHD.

Objective 2: Describe the current health seeking behavior of children who have a sore throat, including barriers and facilitators to seeking care within the formal healthcare system.

Objective 3: Describe the current approach by health care workers to a child presenting with sore throat, including barriers and facilitators to guideline-based care for children with sore throats.
 Uganda 2024-01-08 13:11:15 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daudi Jjingo
ID:
AI for Health Equity: Transforming Pandemic Preparedness in Uganda (HEAL)
REFNo: HS3524ES

Primary objective: To leverage advanced Large Language Models (LLMs) like GPT-4 to convert the Uganda Ministry of Health pandemic preparedness guidelines and the National Action Plan for Health Security (NAPHS) into an interactive, conversation-based tool, accessible in a native African language. Secondary objective: To validate the effectiveness of the dynamic AI platform encompassing language adaptation, user satisfaction and perception, seamless implementation in clinical settings, and tangible impact on clinical decision-making by conducting focused field testing involving a group of 60 healthcare professionals.
Uganda 2024-01-08 13:08:26 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 ADAPTATION, FEASIBILITY AND ACCEPTABILITY OF CAREGIVER PEER-SUPPORTER FACILITATED HIV STATUS DISCLOSURE INTEVERNTION FOR CHILDREN IN EASTERN UGANDA – A TASK SHIFTING MODEL
REFNo: HS3547ES

To assess the feasibility and acceptability of the CPS facilitated disclosure intervention ,1. To culturally adapt a clinic-based pediatric HIV status disclosure intervention into CPS facilitated HIV status disclosure intervention among CLHIV and their caregivers in Uganda,To culturally adapt and assess the feasibility and acceptability of a CPS-facilitated HIV status disclosure intervention among caregivers of CLHIV at Jinja Regional Referral Hospital in Eastern Uganda. ,
 Uganda 2024-01-08 13:07:36 2027-01-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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