Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Bibangambah Mulungi Nabatanzi
ID: UNCST-2024-R004669
 Health Related Quality of Life of children with Cerebral Palsy in Wakiso District: An Explorative interventional study
REFNo: HS4516ES

4. Evaluate the impact of both hospital-based and community-based early intervention program on Health-Related Quality of Life of children with Cerebral Palsy and the depression anxiety and stress level of their primary caregivers. ,3. Define the depression, anxiety and stress of primary caregivers of children with Cerebral Palsy in Wakiso, Uganda,2. Define the Health-Related Quality of Life of children with CP in Wakiso, Uganda,1. Define the epidemiology of Cerebral Palsy in Wakiso, Uganda,We aim to establish a cohort of children with CP in the Wakiso district of Uganda to define the epidemiology of CP, describe the HRQoL of the children with CP and depression, anxiety and stress level their primary caregivers to evaluate the impact of any community-based early intervention. ,
 Uganda 2024-08-28 18:51:55 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ACEN CATHERINE BOKELLO
ID: UNCST-2024-R004924
 Internal Control Systems and Public Financial Management in Selected Local Governments in Uganda
REFNo: SS2809ES

To determine the significant relationship between monitoring and public financial management in selected local governments in Uganda.,To establish the influence of communication on public financial management in selected local governments in Uganda,To establish the effect of control activities on public financial management in selected local governments in Uganda,To establish the influence of risk assessment on public financial management in selected local governments in Uganda.,To determine the effects of control environment on public financial management in selected local governments in Uganda,To assess the effects of internal control systems on public financial management in selected Local Governments, in Uganda.,
 Uganda 2024-08-28 18:49:02 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Beatrice Kyasiimire
ID:
Living near Uganda’s Queen Elizabeth National Park; evaluating alternative livelihood initiatives
REFNo: NS830ES

Assess communities\' governance structures and systems\' impacts on alternative livelihoods around the park.,Assess community and external actors\' perceptions of the enabling conditions for alternative livelihood projects around the park.,Evaluate the enabling conditions for alternative livelihood projects in communities around Queen Elizabeth National Park.,The overall aim of this study is to understand the enabling conditions influencing the implementation and effectiveness of alternative livelihoods around Queen Elizabeth National Park. ,
 Uganda 2024-08-28 18:46:54 2027-08-28 Natural Sciences Non-Clinical Trial Degree Award
SHAFIGA BABIRYE
ID: UNCST-2024-R004302
 LEVEL AND PREDICTORS OF CATASTROPHIC HEALTH EXPENDITURE AMONG RECIPIENTS OF AMBULATORY SURGICAL SERVICES AT KYABIRWA SURGICAL CENTER
REFNo: SS2900ES

To establish the intra-household predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To analyze the clinical predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the intrapersonal predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To determine the prevalence of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,To assess the level and predictors of Catastrophic Health Expenditure among recipients of ambulatory surgical care services at Kyabirwa surgical center,
 Uganda 2024-08-28 18:41:10 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 Exploring the Nexus of Clean Water Access and Sexual Reproductive Health among Women and Girls in Rural Uganda
REFNo: SS2829ES

1. How do socio-cultural contexts, such as traditional gender roles and community expectations, shape the challenges women and girls face when accessing clean water?
2. How do power dynamics influence the management, utilization, and involvement of women in activities related to water access?
3. What role does education play on the awareness and implementation of Sexual Reproductive Health practices among women and girls?

Uganda 2024-08-28 18:39:31 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hadijah Yahyah
ID:
Assessing the Environmental Sustainability Implications of Farm-Level Persistent Organic Pollutant Pesticide Use in Uganda
REFNo: SS2683ES

1. To examine the pathways for the transmission of POPs pesticides into Mukono District;
2. To evaluate the trends and characteristics of farm level use of POP pesticides into Mukono District;
3. To assess the role and level of knowledge, attitudes and practices of farmers in decision making for POPs pesticide use in Mukono District;
4. To assess the adequacy of the existing structures , tools, and approaches for the regulation of importation and farm-level use of POP pesticides in Uganda;

 Uganda 2024-08-28 18:31:37 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Nakaye
ID: UNCST-2021-R013222
 FEASIBILITY, ACCEPTABILITY, AND PERSISTENCE OF COMMUNITY DRUG SHOP-BASED HIV SELF-TESTING AND ORAL PREP DELIVERY AMONG FEMALE SEX WORKERS IN KITEBI, KAMPALA CAPITAL CITY, CENTRAL UGANDA (DROP-D).
REFNo: HS4556ES

Examine FSW and community drug shop PrEP providers’ experiences, preferences, barriers, and facilitators related to the community drug shop based HIVST and oral PrEP delivery model,Assess persistence of community drug shop-based HIVST and oral PrEP delivery among FSW in Kampala,Assess the feasibility and acceptability of utilising community drug shops to offer HIVST and oral PrEP delivery among FSW in Kampala,
 Uganda 2024-08-28 18:28:21 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Semyalo Paul Ddumba
ID: UNCST-2021-R012585
 RISING INEQUALITIES OCCASIONED BY COVID-19 IMPACTS IN URBAN INFORMAL SETTLEMENT IN UGANDA (CASE STUDY OF ACCESS AND USE OF SAFE WATER IN KAMPALA SLUM AREAS)
REFNo: NS746ES

To assess microbiological and physicochemical water quality both at the source and household reserves, as well as carryout sanitation risk assessment of the different water sources in Kisenyi.,To assess the patterns of access to and utilization of safe water among households in Kisenyi, Central Division, examining the changes that occurred before, during, and after the COVID-19 pandemic.,To investigate the diverse socio-economic determinants of households in Kisenyi which influences their choice of water source and how this was impacted by COVID-19.,Examine the multifaceted impact of the COVID-19 pandemic on the exacerbation of social and economic inequalities among the urban poor, with a specific focus on access to Water, Sanitation, and Hygiene (WASH) services, as a means to gain insights and inform strategies for addressing these disparities.,
 Uganda 2024-08-28 18:19:09 2027-08-28 Natural Sciences Non-Clinical Trial Non-degree Award
ERINAH MUDONDO -
ID:
Liquidity management practices and Financial performance of banking institution in Kampala metropolitan - Uganda
REFNo: SS2872ES

To establish the influence of liquidity risk on the financial performance of banking institutions in Kampala Metropolitan.,To investigate the influence of liquidity management practices on financial performance of banking institutions in Kampala Metropolitan, Uganda.,
 Uganda 2024-08-28 18:17:15 2027-08-28 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Downing George
ID: UNCST-2020-R014615
 A prospective, multi-centre study to evaluate the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test.
REFNo: HS4648ES


The primary objective of this study is:
• To determine the diagnostic sensitivity and specificity of the Determine Syphilis Advanced test results using fingerstick capillary whole blood, venous whole blood, serum and venous plasma, when the test is performed by professional users.

The reference test will be Elecsys® Syphilis test (Roche). This test is an electrochemiluminescence immunoassay for the qualitative determination of total antibodies against Treponema pallidum. Samples with a negative Elecsys Syphilis result will be considered reference test-negative. Samples with a positive Elecsys Syphilis result will be confirmed by Treponema Pallidum Particle Agglutination (TPPA) testing. The TPPA result must be positive for the sample to be considered reference test-positive. Samples with a positive Elecsys Syphilis result but a negative or indeterminate TPPA result will be considered indeterminate and excluded from the study analyses. Potential discrepant result resolution using the Abbott Architect i1000SR Syphilis chemiluminescent microparticle immunoassay may be conducted for study reference test-positive or reference test-negative samples with discrepant investigational test results. The results from potential discrepant result resolution testing will be presented as table footnotes only. In addition to these treponemal tests, non-treponemal RPR testing will also be conducted for the reference test-positive participants, and the results may be stratified also by RPR status. All discrepant specimens shall be repeated using the same lot of RDT, and then on all available lots and any variability noted.

Another primary study objective is to compare the performance of the Determine Syphilis Advanced test with two commercially available similar tests, to meet the regulatory requirements in Japan. These two commercially available tests will be the TPPA test (SERODIA-TPPA, Fujirebio, Japan) and the Determine Syphilis TP test (Abbott). This analysis will be performed using 60 reference test-positive samples and 60 reference test-negative samples. The testing will be performed using plasma.

One study secondary objective is to evaluate the usability through completion of a user experience questionnaire (healthcare and laboratory staff).

Another study secondary objective is to determine the stability of venous whole blood, serum and plasma samples for use with Determine Syphilis Advanced, after refrigeration of the venous whole blood, serum and plasma at 2-8 degrees Celsius during 7 days before testing.

 UK 2024-08-28 17:34:38 2027-08-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hillary Agaba
ID:
Understanding experiences of participating in a farmer research network from multiple perspectives in the Agroecology - Landscape project in Eastern Uganda
REFNo: SS2707ES

Provide an overview of the diversity of experiences across the Collaborative Resilient Food Systems (CRFS) countries, and different projects within countries, in ESAf. ,Gain more understanding of how FRN groups have developed and are functioning from the perspectives of those involved, ,Document the experience of participating in Farmer Research network (FRN) from multiple perspectives: farmers, researchers, NGO field staff and extension workers;,
 Uganda 2024-08-28 17:32:34 2027-08-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
 Comparing the Diagnostic Performance of the Rapid Tick Exposure Test (RaTexT®) and Larval Packet Test [LPT] for Acaricide Resistance Management in Uganda
REFNo: NS843ES

The general objective of this study will be to determine the diagnostic performance of RaTexT® compared to larval packet technique, test a mobile application for its ability to capture acaricide resistance data generated by RaTexT® and transmit it to end users as dynamic maps of acaricide resistance as well as determine the gender roles that are likely to underpin successful RaTexT® introduction. The specific objectives of this acaricide study will be to determine:
i.Laboratory and field diagnostic performance [specificity, sensitivity, negative and positive predictive values] of RaTexT® when used to detect acaricide resistance in tick populations isolated from different agro-ecological zones of Uganda.
ii. Possibility of integrating RaTexT® -generated acaricide resistance | susceptibility data into a mobile phone app to allow end-users to create dynamic maps of acaricide resistance in different African ecologies.
iii.Gender-based drivers of successful introduction and sustainable utilisation of RaTexT®

 Uganda 2024-08-28 17:31:08 2027-08-28 Natural Sciences Non-Clinical Trial Non-degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
 Zinc for Infection Prevention in Sickle cell anemia ZIPS-2
REFNo: HS4824ES

The primary objective of the study is to determine if zinc supplementation at 20mg daily is safe and efficacious at reducing all-cause infection in Ugandan children 1.00-4.99 years of age with SCA.Secondary objectives 1. To determine the incidence of adverse events requiring discontinuation of study drug in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 2. To determine the incidence of stroke or death in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 3. To determine the incidence of infections requiring hospitalization in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 4. To determine the incidence of vaso-occlusive crises in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 5. To determine the change in transcranial Doppler (TCD) velocity from enrollment to 6-month study endpoint in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 6. To determine change in serum zinc deficiency status from enrollment to 6-month study endpoint in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 7. To determine the incidence of serious adverse events in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo 8. To determine the incidence of adverse events in children ages 1-4.99 supplemented with 20mg of daily zinc vs placebo
Uganda 2024-08-28 17:29:12 2027-08-28 Medical and Health Sciences Clinical Trial Non-degree Award
Esther Nakyaze
ID:
Provider Perspectives on the PrEP Ring (“ProPrEP”): views from a maternal and child health program (“BAMA”) serving young mothers in rural Uganda.
REFNo: HS4468ES

General Objective
The study will deepen our understanding of provider perspectives on use of the PrEP vaginal ring among young mothers living in rural areas of Uganda.
Specific Objectives
1. Identify preliminary areas for education and outreach to improve both provider and end-user understanding/knowledge of the new vaginal ring technology, thus increasing likelihood of quality counseling and uptake among a vulnerable population of young mothers.
2. Explore the reception by health care personnel of promotional and information/education/counseling (IEC) materials developed by the multilateral “Catalyst” study (funded by PEPFAR through USAID) for ring launch, especially in rural regions having distinct health services resources; identify areas for possible adaptation or elaboration for best uptake and use by health workers
3. Expand understanding of facilitators and barriers faced by young mothers in accessing HIV prevention information and services, especially:
a. community and peer-based stigma
b. provider attitudes
c. models of service provision linking maternal health and HIV prevention/care

Uganda 2024-08-26 18:29:44 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
 Epidemiological Profile of Malaria and Molecular Characterization to Assess Presence and Potential Contribution of Emerging Parasite Populations to Malaria Epidemics in Epidemic Districts in Eastern Uganda
REFNo: HS4786ES

General objective
To describe the epidemiological profile of malaria and assess presence and potential contribution of new emerging parasite populations to persistent epidemics in malaria
epidemic districts in Eastern Uganda
Specific objectives
1. To describe the trend and epidemiological profile of malaria in five epidemic districts in Eastern
Uganda over the past 5-year period
2 . To assess presence and potential contribution of emerging parasite species to epidemics by
molecular characterization of malaria parasite populations in epidemic districts in Eastern Uganda
3 . To assess presence and potential contribution of emerging parasite populations harboring
molecular markers of artemisinin resistance to persistent epidemics in malaria epidemic districts
in Eastern Uganda
4 . To assess presence and potential contribution of emerging parasite populations harboring pfhrp2
and pfhrp3 gene deletions to the persistent epidemics in malaria epidemic districts in Eastern Uganda
 Uganda 2024-08-26 18:28:33 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
MUGISHA TAREMWA IVAN
ID: UNCST-2024-R004274
 Assessment of Transfusion Safety and Efficacy among Cancer Patients in Uganda and Caregivers’ Perceptions on Blood Use.
REFNo: HS4848ES

Specific objectives: (i). To assess the level of bacterial contamination in stored whole blood and blood components intended for transfusion to patients with cancer at Mbarara Regional Referral Hospital and Uganda Cancer Institute. (ii). To determine the prevalence of, and the factors associated with immune sensitization among patients with hematological malignancies at Mbarara Regional Referral Hospital and Uganda Cancer Institute. (iii). To identify the specificities of anti-RBC alloantibodies in patients with hematological malignancies at Mbarara Regional Referral Hospital and Uganda Cancer Institute (iv). To determine the incidence of acute and delayed serologic or delayed hemolytic transfusion reactions among patients with cancer at Mbarara Regional Referral Hospital and Uganda Cancer Institute (v). To describe the caregivers' perceptions of blood use and availability in southwestern Uganda. Main objective: To assess transfusion safety and efficacy among patients with cancer in Uganda and caregivers’ perceptions of blood use.
 Uganda 2024-08-26 18:26:57 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Edward  Tumwesige
ID: UNCST-2024-R003855
 Assessing Community Willingness and Acceptance to Utilize Locally Developed Vaccines
REFNo: SS2875ES

• Assess the community's level of knowledge and awareness regarding locally developed vaccines.
• Explore trust and willingness of the community to utilise locally developed vaccines.
• Identify factors contributing to positive or negative perceptions of locally developed vaccines.
• Explore the most effective communication channels for sharing information about locally developed vaccines.

 Uganda 2024-08-26 18:25:34 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
ASUMAN KHAMIS SHAFI
ID:
Timing Of Neurosurgical Intervention And Short-term Outcome Of Patients With Traumatic Brain Injury Admitted To Mulago Hospital Emergency Department
REFNo: HS4610ES

1. To determine the average decision-to-intervention time among patients with TBI admitted at MNRH ED. 2. To determine factors associated with the neurosurgical intervention among patients with TBI admitted to the MNRH ED. 3. To determine the 72-hour outcome mong patients with TBI requiring neurosurgical intervention admitted to MNRH ED.
 Uganda 2024-08-26 18:24:09 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Patience Kinengyere Bemanya
ID: UNCST-2024-R004964
 PROJECT EVALUATION FOR THE INCREASING EQUITABLE ACCESS TO EFFECTIVE CATARACT SERVICES IN WEST, SOUTH, AND SOUTH-WESTERN UGANDA PROJECT
REFNo: SS2923ES

6. To evaluate the impact on the broader health system, including the referral system and the ability to handle increased demand for eye health services. ,5. To analyse the efficiency of operational processes within the project, including infrastructure development, capacity-building initiatives, and improvements in surgical procedures. ,4. To assess the extent of integrating health services for women with eye care services, its merits and demerits, challenges encountered, and the factors for scalability/sustainability. ,3. To evaluate the project’s success in promoting equity and inclusivity in health service delivery, mainly focusing on gender-specific barriers and access challenges marginalised populations face. ,2. To examine the effectiveness of community engagement strategies and awareness activities in increasing eye health awareness, improving access to services, increasing uptake of eye care services and reducing barriers to access to eye health services.,1. To evaluate overall project impact and effectiveness in terms of increasing equitable access to adequate services, improving service quality, achieving gender equity in eye health and reducing cataract-related blindness in the project area. ,To assess the extent to which the project\'s two components have met their objectives, key outputs, outcomes, and overall impact. It will also validate the monitoring data collected by in-country program teams during implementation. It will contribute to improvement by extracting valuable lessons from each part of the project. These insights will be instrumental in enhancing current and future programming within the region, guiding the development of future projects, and evaluating the potential scalability of the project to improve eye health.,
 Uganda 2024-08-26 18:22:11 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
 Tailoring community ART delivery to the needs and preferences of people living with HIV in refugee settlements in Uganda
REFNo: HS4193ES

The overarching objective of the proposed study is to evaluate how community ART delivery can be optimized for people living with HIV (PLHIV) in refugee settlements in Uganda.
Specific aims:
Aim 1A: To identify key barriers to community antiretroviral therapy (ART) delivery participation and implementation in refugee settlements experienced by PLHIV, health workers, and expert clients.
Aim 1B: To characterize perspectives of PLHIV, health workers, and expert clients on the optimal design of community ART delivery for refugee settlements.
Aim 2: To quantify community ART delivery preferences among PLHIV in refugee settlements and identify demographic groups with similar preference profiles.

 Uganda 2024-08-26 18:17:13 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FREDDIE SSENGOOBA Peter
ID: UNCST-2021-R011834
 Estimating the cost of introduction, delivery and budget impact of malaria vaccine introduction in Uganda (A prospective projection)
REFNo: HS4096ES

4. To determine the budget impact of introducing and delivering Malaria vaccine among children under five years in Uganda. ,3. To estimate and compare the cost of delivering the malaria vaccine under different vaccination modalities/approaches,2. To estimate the additional resource requirements for the introduction and rollout of the malaria vaccine into Uganda’s routine immunizations programme.,1. To explore perspectives of key stakeholders on Uganda’s plan to introduce the malaria vaccine among children under five years.,To estimate the incremental resources (cost) and budget impact of introducing the new malaria vaccine in Uganda to inform the country decision-making regarding the introduction, delivery, national scale-up, as well as impact of the malaria vaccine on other vaccines in the routine immunization system.,
 Uganda 2024-08-26 18:14:03 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kisembo Vincent
ID: UNCST-2024-R003679
 NATURAL RESOURCE GOVERNANCE AND HUMAN-ECOLOGICAL WELLBEING IN THE OIL AND GAS SUB SECTOR IN BUNYORO SUB-REGION
REFNo: SS2971ES

the study's main objective is to assess natural resource governance and human-ecological wellbeing in the oil and gas sub sector in Bunyoro sub-region, specifically in the districts of Hoima, Kikuube and Buliisa.
Specifically, the study aims to;
1. To analyse the established legal and institutional framework for oil natural resource governance in ensuring the well-being of human -ecological wellbeing in Buliisa, Hoima and Kikuube districts
2. To examine the policies on human wellbeing to the communities in the Oil and Gas sub sector in Buliisa, Hoima and Kikuube districts
3. To analyze the implications of oil and gas sub sector activities on ecological wellbeing in Buliisa, Hoima and Kikuube districts.
4. To examine social and environmental challenges emanating from Oil and gas activities in Buliisa, Hoima and Kikuube districts

Uganda 2024-08-26 15:11:29 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Teopista Akoyi Kevin
ID: UNCST-2024-R004534
 AfriFoodLinks Project - Mbale City Research
REFNo: SS2990ES

d. Actively engage government actors, creating a project feedback mechanism. ,c. Engage other project work packages towards constructing positions on multi-level governance, agri-food system entrepreneurship and innovation and urban food environments,b. Actively contribute to development of urban food system researcher network in partner African cities,a. Support the generation of new and path-leading urban food systems knowledge,to generate scientific evidence to inform actions geared towards transforming urban food systems in such a manner that tackles the systemic foundations of food insecurity and environmental impact.,
 Uganda 2024-08-26 15:00:52 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Herbert Ainamani Elvis
ID: UNCST-2020-R014674
 The Impact of Self Help Plus and Climate Smart Agriculture on Mental Health and Food Security in the Rhino and Nakivale Refugee Settlements of Uganda
REFNo: HS4691ES

To compare the uptake of HGI between the mothers in the combined intervention group (HGI & SH+) with those in the HGI group living in Nakivale refugee settlement,To assess the effect of SH+ on the development of children aged 3-6 years belonging to participating mothers living in Rhino and Nakivale refugee settlements,To assess the effect of SH+ on the mental health of mothers with children aged 3-6 years living in Rhino and Nakivale refugee settlements ,To assess the perceptions and attitudes towards a home gardening intervention (HGI) among participating mothers living in Nakivale refugee settlement,To assess the effectiveness of Self Help Plus (SH+) and home gardening on maternal mental health, food security and child development in the Rhino and Nakivale refugee settlements of Uganda,
 Uganda 2024-08-26 14:58:27 2027-08-26 Medical and Health Sciences Clinical Trial Non-degree Award
Richard Mayanja Weazher
ID:
cultural practice and consumption of indigenous iron artifacts of the Baganda people in Uganda
REFNo: SS2942ES

3. To analyze the extent to which indigenous knowledge of ironworks of the Baganda in Central and Southern Uganda has survived.,2. To examine the historical and contemporary relevance of Indigenous iron implements to the Baganda in Central and Southern Uganda.,1. To document the indigenous knowledge embedded in the design production of the indigenous ironworks of the Baganda in Central and Southern Uganda.,The purpose of this study is to document the cultural practice and consumption of the indigenous iron art forms of the Baganda in central and southern Uganda for posterity. ,
 Uganda 2024-08-26 14:55:51 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Claire Norcross Valerie
ID: UNCST-2024-R004641
 An observational study evaluating archived and emergent HIV drug resistance in people with a history of sub-optimal HIV control in East and Southern Africa
REFNo: HS4761ES

1. To describe archived resistance mutation patterns (major/minor mutations and minority variants) in adults in East and Southern Africa with a recent history of sub-optimal adherence to dolutegravir-based ART; through next-generation sequencing of pro-viral DNA 2. To describe emergent resistance patterns (major/minor mutations and minority variants) in people living with HIV (PLWH) who fail treatment with long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) and the implications for future treatment, and in those who experience blips on LAI-CAB/RPV, through next-generation sequencing on stored plasma 3. To identify predictors of treatment failure on LAI-CAB/RPV in PLWH in East and Southern Africa, and consider how these predictors can influence policy
UK 2024-08-26 14:52:18 2027-08-26 Medical and Health Sciences Non-Clinical Trial Degree Award
David Okimait
ID: UNCST-2019-R000095
 We Can Work Baseline for Youth With Disability
REFNo: SS3023ES

To provide relevant recommendations and insights that will further inform the program design and adaptation during the implementation period.,To measure all goal, outcome, and output level indicators as a benchmark for purposes of setting performance targets and measurement of the program progress,The overall purpose of this baseline survey is to establish a benchmark of the program indicators across all five outcomes to inform implementation. This will enable systematic measurement of progress towards the intended results annually and at final evaluation,
 Uganda 2024-08-26 14:45:41 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
FREDRICK MAKUMBI
ID:
Rapid Assessment of Bottlenecks Inhibiting the Scale-up of Evidence-based Family Planning Practices in Uganda
REFNo: HS4723ES

Broad objective To understand enablers and inhibitors to the scale-up of three EBPs (PPFP, task sharing/expansion, and SBCC) and FP broadly through a BNA approach to inform strategies that can accelerate the uptake of family planning services and programme implementation in Uganda. Specific objectives 1.To synthesize what is known about scaling up FP EBPs and broader FP in Uganda, including implementation status, alignment of guidance with national and international standards, and the lessons learned from successful implementation (including approaches that aim to address gender norms and inequalities) 2.To understand the perspectives of key stakeholders (policymakers, programme managers, healthcare managers, service providers and civil society) on the various health systems factors inhibiting the scale-up of the EBPs. 3.Build consensus among key stakeholders on the most important bottlenecks to EBP scale-up and on solutions that address the root causes inhibiting scale-up
Uganda 2024-08-26 14:41:30 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 What works to prevent and respond to childhood sexual violence in resource-constrained settings: The Case of the 3RT Model implemented by The Remnant Generation in Uganda
REFNo: SS3005ES

4. To study the contribution of girls’ agency in promoting social norms change to prevent childhood sexual violence.,3. To identify critical enablers for effective implementation of interventions to prevent and respond to childhood sexual violence.,2. To explore the role of communities in leading sustainable change for safe environments free from childhood sexual violence. ,To document the effectiveness of the 3RT model in preventing and responding to childhood sexual violence among adolescents in Uganda.,To scientifically examine what works in preventing and responding to childhood sexual violence in resource-constrained settings using the 3RT model of the Remnant Generation as a case. ,
 Uganda 2024-08-26 14:40:04 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Warren Aryeija
ID:
Experiences of People with Infertility in Uganda: Empirical Study of Couples with Infertility Challenges at Selected Hospitals in Kampala City
REFNo: SS2807ES

1. Assess knowledge about the causes of infertility among infertile male and female couples. 2. Identify socio-economic challenges experienced by infertile male and female couples. 3. Examine the psycho-emotional impact of infertility on infertile male and female couples. 4. Explore Coping strategies used by infertile male and female couples in living and dealing with infertility. 5. Determine the Socio-demographic correlates of Coping Strategies adopted by infertile male and female couples.
 Uganda 2024-08-26 14:21:31 2027-08-26 Social Science and Humanities Non-Clinical Trial Degree Award
Monicah Agaba
ID: UNCST-2024-R004221
 The Health-Beauty Paradox among Women in Mbarara City Uganda
REFNo: HS4708ES

iii. To characterise the cardio-metabolic profile of WRA.,ii. To document the risk behaviours and their factors related to these societal beauty perceptions.,i. To document societal beauty perceptions and their determinants.,To understand what, why and how the health-beauty paradox is so deeply entrenched in the culture.,
 Uganda 2024-08-26 10:18:37 2027-08-26 Medical and Health Sciences Clinical Trial Degree Award
George William Ddaaki
ID: UNCST-2022-R009216
 Exploring perceptions, concerns, and perceived benefits of pregnant women and those intending to become pregnant towards participating in HIV cure research.
REFNo: SS2866ES

a) To identify concerns and perceived benefits among women in south central Uganda regarding their participation in HIV cure studies.
b) To explore the perceptions and attitudes of pregnant women and those intending to become pregnant in south central Uganda towards participating in a study focused on impact of pregnancy on the HIV viral reservoir and HIV cure.

 Uganda 2024-08-26 10:14:01 2027-08-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Implementing comprehensive malaria surveillance at sentinel sites in Uganda
REFNo: HS4692ES

To monitor geographic and temporal trends in malaria burden and assess the impact of population level control interventions across a range of epidemiological settings in Uganda.
 Uganda 2024-08-26 10:12:47 2027-08-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRANCIS KIBIRIGE
ID:
GENDER REFORMS AND POLITICAL SYSTEMS IN UGANDA
REFNo: SS2985ES

The broad objective is to put in context the emerging gender programming reforms in Uganda, particularly the persistent narrative that despite the success in policies that promote women in governance, leadership and employment roles, women voices continue to lag behind.

As a secondary objective, the survey also seeks to increase our understanding of how physical and psychological violence targeting political candidates impacts adult Ugandans’ willingness to engage in electoral politics.


Uganda 2024-08-22 16:38:35 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Irene Mutuzo Esther
ID:
Usability Context and Adoption of Human Capital Management Systems in Ugandan Public Universities: Application of the Unified Theory of Acceptance and Use of Technology
REFNo: SS2972ES

Purpose
This study aims to investigate the influence of usability context on the adoption of HCMS in Ugandan Public Universities by using variables from Venkatesh et al.’s (2003) UTAUT theory.

Objectives
The study will focus on the following objectives:
1. To investigate the influence of performance expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
2. To assess the influence of effort expectancy on Ugandan public university staff behaviour intention to adopt HCMS.
3. To investigate the influence of social influence on Ugandan public university staff behaviour intention to adopt HCMS.
4. To examine the influence of facilitating conditions on Ugandan public university staff’s actual use of HCMS.
5. To investigate the influence of Ugandan public university staff behaviour intention on their actual use of HCMS.
6. To investigate the moderating effect of user background characteristics (gender, voluntariness of use, age, and experience) on the relationship between usability context constructs and the adoption of HCMS among Ugandan public university staff.

Research Questions
The study will focus on the following research questions:
1. What are the obstacles impeding the adoption of HCMS in Ugandan public universities, and how can they be addressed?
2. What are the enabling factors facilitating the adoption of HCMS in Ugandan public universities, and how can they be enhanced?

 Uganda 2024-08-22 16:35:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jose Rubio Valverde Ricardo
ID: UNCST-2024-R003911
 Evaluation of the Pathways out of Poverty (POP) project in the Kitagwenda and Rakai districts of Uganda
REFNo: SS3052ES


1. Assessing the achievement of objectives: The evaluation aims to assess whether POP\'s objectives are achieved, including increasing household income to $2.25/day, reducing the average household Poverty Probability Index score to 22 or less, and ensuring that 60% of households feel their quality of life has improved within 24 months of each cohort\'s initiation.

2. Estimating causal impact: On priority outcomes for HWG - including grow and net household income, household asset endowment, coffee revenue and profits, best practice adoption and yield – the goal is to determine whether it is possible to establish causal inference on the effects of the program on these variables.

3. Conducting heterogeneous treatment effects analysis: The evaluation will analyze variances in the estimated treatment effect across different demographic groups, with a focus on geographic, economic, social and gender factors.

4. Understanding pathways of change: Core to HWG’s agenda is identifying which project components are vital for driving primary outcomes. The evaluation will aim to dissect the project’s multifaceted initiatives to delineate the most impactful pathways tied to changes in income and agricultural productivity.

5. Determining the importance of coffee: With HWG placing a strong emphasis on the role of coffee in household income, the evaluation will focus on measuring how coffee-centered interventions contribute to the broader project outcomes, tying coffee profit and revenue analyses to holistic changes in income.

6. Identifying unintended consequences: The evaluation should also scrutinize potential negative impacts on the environment, health, human rights, community dynamics, and gender equity, such as the effects of agrochemical use, deforestation, community conflicts, labor issues, and changes in household dynamics and resource control.

7. Suggesting operational improvements: Finally, the evaluation should provide actionable insights and recommendations during the implementation period, to increase the efficacy of POP.

 Netherlands 2024-08-22 16:33:12 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
JOSEPH  MURANGIRA
ID:
STRATEGIC MANAGEMENT PRACTICES AND LEGAL CERTAINTY IN UGANDA JUDICIARY
REFNo: SS2917ES

i. To evaluate the effect of strategy formulation on legal certainty in Uganda Judiciary.
ii. To assess the effect of strategy implementation on legal certainty in Uganda Judiciary.
iii. To assess the effect of strategy evaluation on legal certainty in Uganda Judiciary.
iv. To investigate the effect of strategic control on legal certainty in Uganda Judiciary.


 Uganda 2024-08-22 16:30:00 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability. "CPSP nr ASH-CPH 23-045"
REFNo: HS4685ES

The objective of this evaluation is to establish the performance of the HBsAg Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series (TSS) for submission to WHO Prequalification – Diagnostic Assessment: TSS-13.,
 Uganda 2024-08-22 16:24:28 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Anti-HCV Rapid Test Device (Whole Blood/Serum/Plasma) (AssureTech) - diagnostic specificity, specimen equivalence and qualification of usability.
REFNo: HS4703ES

The objective of this evaluation is to establish the performance of the HCV Rapid Test Device (Whole Blood/Serum/Plasma) in accordance with the COMMISSION IMPLEMENTING REGULATION (EU) 2022/1107 of 4 July 2022 laying down common specifications for certain class D in vitro diagnostic medical devices in accordance with Regulation (EU) 2017/746 of the European Parliament and of the Council and, the Technical Specifications Series for submission to WHO Prequalification – Diagnostic Assessment: TSS-16 (2021 update).,
 Uganda 2024-08-22 16:20:33 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Linda Grace  Alanyo
ID:
The Role of Social Capital in Enhancing the Reproductive Autonomy of Adolescent Girls in Uganda
REFNo: SS2627ES

To explore the perspectives of immediate caretakers and other stake holders on barriers and facilitators to Reproductive autonomy of adolescent girls,To Assess the Reproductive autonomy of Adolescent girls in Uganda and associated socio-ecological factors ,To synthesize evidence on factors associated with the reproductive autonomy of adolescent girls.,To understand the role of social capital in enhancing the Reproductive Autonomy of Adolescent girls in Uganda,
 Uganda 2024-08-22 16:15:47 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
 Promotion of a Safe Workplace Environment, Free from Gender-based Discrimination and Violence: A Policy Review and Action Research on the Prevalence of Workplace Gender Discrimination and Violence within the Agriculture, Tourism and Hospitality Sectors in the Rwenzori and Albertine Regions in Uganda
REFNo: SS2600ES

Develop action plans (1 per sector) based on research findings to address gender-based discrimination and violence, and create safe and inclusive work environments.,Identify support structures and mechanisms for work related Gender based discrimination and violence victims available in the region. ,Analyse existing policies and their gaps to address gender-based discrimination and violence at the workplace targeting selected sectors in Albertine and Rwenzori regions. ,To conduct action-oriented research on gender-based discrimination and gender-based violence (GBV) at the workplace targeting agriculture, tourism, and hospitality sectors in the Albertine and Rwenzori regions.,To contribute to the promotion of a Safe Workplace Environment, free from gender-based discrimination and gender-based violence.,
 Uganda 2024-08-22 15:26:06 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kelsey Shaw
ID:
In-situ assessment and collection of fecal sludge from non-sewered sanitation containments: Linking demographic, environmental and technical parameters to microbial activity
REFNo: SIR275ES

The overall objective of this PhD project is to better understand and characterize anaerobic degradation pathways in containment of non-sewered sanitation systems (NSS) in resource constrained settings representative of both urban and rural areas. In view of this, the specific objective linked to this research pertaining to this ethics application is to understand the influence of demographic, environmental and technical (DET) data on measurable fecal sludge parameters as well as microbial community composition within NSS containment across variable geographic regions. The proposed project aims to answer the following specific research questions: - What are the effects and variations associated with physical location, use, and operating conditions on wastewater quality and microbial composition? - What is the relationship between location of sanitation system and behaviors associated with operational parameters? - Is there a link between main concentration gradients in containment and spatially analyzable factors (i.e., demographic, environmental and technical)?
Canada 2024-08-22 15:18:53 2027-08-22 Engineering and Technology Non-Clinical Trial Degree Award
Luke Nyakarahuka
ID: UNCST-2023-R008138
 Surveillance and Research of Viral Hemorrhagic Fever Outbreaks in Uganda: Acute Case Investigation and Survivor Follow-up for Strategic Public Health Intervention
REFNo: HS2964ES

The primary objective is to enhance Uganda’s capacity to rapidly detect, diagnose, respond to, and prevent VHFs including those caused by Ebola, Marburg, CCHF, RVF, Sosuga, and other emerging viruses. To do this, it is critical to understand the incidence, distribution, risk factors for emergence and transmission, immunogenicity and clinical progression (including potential asymptomatic infection), and potential for transmission following clinical recovery of these diseases throughout Uganda, which will enable improved VHF case outcomes, identification of unknown chains of transmission, survivor monitoring, and strategic targeting of public health and animal health resources to prevent and control transmission of these high-consequence viruses.
 Uganda 2024-08-22 15:14:36 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nuwematsiko
ID: UNCST-2022-R010501
 Effect and implementation factors of a contextually adapted short message service or phone call intervention to reduce loss to follow-up among presumptive TB patients in North Central Uganda
REFNo: HS3000ES

1.To determine the proportion of pre-diagnosis LTFU among presumptive TB patients and influencing factors in North Central Uganda (Sub-study 1). 2.To explore stakeholder’s perceptions on use of an SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda and contextually adapt the interventions (Sub-study 2). 3.To assess the effect of a contextually adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in health care facilities in North Central Uganda (Sub-study 3). 4.To explore factors that influence implementation of a locally adapted SMS or phone call intervention to reduce LTFU among presumptive TB patients in North Central Uganda (Sub-study 3). 5.To synthesize evidence on effectiveness of mHealth interventions to reduce LTFU in the TB presumption phase in LMICs (Sub-study 4)
Uganda 2024-08-22 13:00:28 2027-08-22 Medical and Health Sciences Clinical Trial Degree Award
AHUMUZA VIANNEY JOHNMARY
ID:
The Refugee Question In Ugandan History 1942-2010
REFNo: SS2297ES

iii. To study the evolution of the relationship between refugees and their host communities,ii. To analyse the changing push and pull factors that shaped refugee flows into and exiting post-Colony Uganda up to 2010.,i. To examine the refugee problem in colonial Uganda.,
 Uganda 2024-08-22 12:54:21 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Mark Okwir
ID: UNCST-2021-R013417
 PREVENTION OF MOTHER-TO-CHILD TRANSMISSION OF HEPATITIS B VIRUS BY ESTABLISHING AN ANTENATAL SCREENING AND VIRAL LOAD TESTING UNIT AND TENOFOVIR DISOPROXIL FUMARATE TREATMENT IN LIRA, NORTHERN UGANDA
REFNo: HS3861ES

To assess the viral load and effectiveness of the TDF therapy.,To assess and enhance knowledge and perceptions of hepatitis B, with the aim of reducing stigma and improving awareness among pregnant women. ,To optimise linkage to care and engagement in the recommended care after receiving a positive HBsAg test during the antenatal period.,To determine the prevalence and risk factors associated with hepatitis B virus infection among pregnant women attending the antenatal clinic in Lira University Hospital and Lira Regional Referral Hospital. ,To assess the implementation of the HBV DNA viral load threshold of ≥10,000 IU/mL for initiating TDF treatment in pregnant women during gestation week 24 or beyond in order to prevent HBV mother-to-child transmission in Lira, Northern Uganda.,
 Uganda 2024-08-22 12:33:06 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Mutekanga
ID: UNCST-2020-R014725
 GEC II Uganda Project
REFNo: SS3024ES

What were the implementation factors behind the GEC-T projects\' success or lack of success? ,To what extent and how did external contextual factors for different projects across the GEC-T portfolio influence their performance?,What were the unexpected or unintended results across the GEC-T portfolio?,What intermediate outcomes did the GEC-T portfolio deliver?,What results did the GEC-T portfolio deliver between the baseline and end line?,The primary objective of the Effectiveness Evaluation will be to assess the effectiveness of the GEC II projects that were designed and implemented through the GEC-T Window. ,
 Uganda 2024-08-22 12:28:28 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
 Universal2: Pharmacokinetics, safety and acceptability of a solid paediatric fixed-dose combination of darunavir/ritonavir (DRV/r) 120/20mg for children living with HIV
REFNo: HS4762ES

To evaluate the pharmacokinetics and safety of DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To evaluate the pharmacokinetics and safety of DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to Less than 25 kg

To evaluate the acceptability of DRV/r tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To evaluate the short-term efficacy of the DRV/r 120/20 mg tablets in children greater than or equal to 3 years of age and weighing 10 to less than 25 kg

To describe RTV PK parameters as well as darunavir unbound plasma concentrations.

 Uganda 2024-08-22 11:45:22 2027-08-22 Medical and Health Sciences Clinical Trial Non-degree Award
Ioana Lungu
ID: UNCST-2024-R004378
 Study protocol for baseline data collection on sexual and reproductive health outcomes in Wakiso district
REFNo: SS3049ES

At baseline and prior to the intervention, assess the uptake of HIV testing, ART and PrEP for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the knowledge, perceived norms and attitudes towards contraception and HIV services (testing, ART and PrEP) for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the modern Contraceptive Prevalence Rate (mCPR) for young women and girls in our samplein study locations.,At baseline and prior to the intervention, assess the level of access to high quality, youth friendly health services for AYP in our sample in study locations.,At baseline and prior to the intervention, assess the share of unintended pregnancies for our sample.,
 Romania 2024-08-22 11:39:54 2027-08-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Agaba Katureebe Ishmael
ID: UNCST-2024-R004089
 Getting a GRIP on Hypertension in Uganda: Giving Repetitive Isometric Exercise for Blood Pressure Control (GRIP in Uganda)
REFNo: HS4712ES

To assess knowledge, attitudes, and practices (KAP) about HTN and experience with IHT (if applicable) ,To measure HTN medication adherence for those prescribed HTN medication during their follow-up, which will be measured through pill counting (counting the remaining amount of pills for prescribed medication).,To assess the need for HTN medication at endline, as per clinical and MOH guidelines, which will be measured through changes in BP levels at week 12,To evaluate the effects of Isometric Hand Training (IHT) on resting diastolic Blood Pressure when compared to standard care after 12 weeks ,To evaluate the effects of Isometric Hand Training (IHT) on resting Systolic Blood Pressure when compared to standard care after 12 weeks ,To determine the efficacy of Isometric Hand Training (IHT) in a population of Hypertension (HTN) patients compared to standard care after 12 weeks of care,
 Uganda 2024-08-22 11:38:26 2027-08-22 Medical and Health Sciences Clinical Trial Non-degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 ASSESSING THE CONTEMPORARY ECHOCARDIOGRAPHIC DIAGNOSIS AND SECONDARY PROPHYLAXIS OF EARLY-STAGE RHEUMATIC HEART DISEASE
REFNo: HS4694ES

a) To determine the diagnostic accuracy of the 2023 World Heart Federation (WHF) echocardiographic screening criteria for RHD, estimate the cost of RHD screening using the WHF 2023 active case finding algorithm, and a cost analysis of two RHD screening models in Uganda; b) To compare patient-reported outcomes (i.e, treatment adherence, treatment satisfaction and health-related quality of life) among children receiving intramuscular and oral forms of penicillin prophylaxis; and c) To evaluate the cost effectiveness of oral versus intramuscular penicillin for treating early-stage RHD.
Uganda 2024-08-22 11:35:35 2027-08-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Wilson Mathembele
ID:
School Inspection and the Quality of Education in Secondary Schools in Uganda: A case Study of Kasese District
REFNo: SS2957ES

To assess the influence of school inspection on the quality of education in secondary schools in Kasese District,To evaluate the quality of education in secondary schools in Kasese District ,To examine the quality of inspection in the secondary schools in Kasese District,The purpose of this study is to determine the effectiveness of school inspection in ensuring the quality of education in secondary schools in Kasese District in order to improve educational standards and quality outcomes.,
 Uganda 2024-08-22 11:30:39 2027-08-22 Social Science and Humanities Non-Clinical Trial Degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Assessment of Longitudinal Lung Function and Sleep Disordered Breathing in COPD Patients in Uganda
REFNo: HS4817ES

1.Assess longitudinal lung function and respiratory symptoms among adults with COPD in Uganda.

2.Determine whether baseline radiographic imaging and inflammatory markers can predict exacerbations at one year among those with COPD.

3.Assess nocturnal sleep patterns and the association between sleep disordered breathing and quality of life.


Uganda 2024-08-22 11:27:08 2027-08-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
 Testing the Feasibility and Acceptability of a Combination Intervention to Address Mental Health among Refugee Youth in Uganda
REFNo: SS2834ES

This proposed two-year study will be conducted in two phases. The first phase seeks to understand whether the COVID-19 pandemic had differential impact on refugee youth living in different settings. The second phase will test the feasibility and acceptability of an innovative combination intervention that has not been previously tested among refugee youth to address psychological problems that have increased since the onset of the COVID-19 pandemic. Aim 1. To examine the mental health impact of COVID-19 on refugee youth living in Bidibidi refugee settlement compared to refugee youth living in urban centers (Arua town) in northern Uganda. Aim 2. To test the feasibility, acceptability and preliminary short-term impact of an innovative intervention combining the youth readiness intervention (YRI) with youth development accounts and financial literacy training (YDA-FLT) to address the mental health impact of COVID-19 among refugee youth living in Bidibidi refugee settlement in northern Uganda.
Uganda 2024-08-19 11:03:04 2027-08-19 Social Science and Humanities Clinical Trial Non-degree Award
Peter Olupot-Olupot Olupot
ID: UNCST-2020-R014798
 SMAART-MAP trial Severe Malaria A Research and Trials consortium - Multisite Adaptive Platform trial
REFNo: HS4547ES

OBJECTIVES
The objective of the SMAART-MAP trial is to identify promising adjunctive therapies to take forward into a large Phase III trial in severe malaria with a mortality endpoint. The adaptive platform design enables additional domains to be added so a range of adjunctive therapies can be tested, across multiple clinical presentations of severe malaria, in a timely manner.

PRIMARY OBJECTIVE(S)
To explore within each domain the therapeutic efficacy of the intervention using an early indicator such as a biomarker or clinical assessment at 24-72 hours.

SECONDARY OBJECTIVE(S)
 To assess the impact of the interventions on clinical outcomes (readmission and
mortality) on all children 28 days and 90 days after randomization
 To assess the impact of the interventions on Grade 3 or 4 adverse events, and adverse
events of any grade related to the interventions or comparators.
 To assess the impact of proposed definitions for severe malaria based on platelet counts
≤150,000/µL and plasma pfHRP2 concentrations ≥800 ng/mL on differences between
randomized groups
 In a sub study, to determine the performance characteristics of a POC pfHRP2 test
compared with quantitative plasma pfHRP2 concentrations determined from plasma.

 Uganda 2024-08-16 11:01:14 2027-08-16 Medical and Health Sciences Clinical Trial Non-degree Award
SYLVIE NAMWASE
ID: UNCST-2024-R003958
 Charcoal Conflict in Climate Change’s Decarbonisation Dilemmas: Knots of Livelihood, Nutrition, Communities, Gender, Migration and Energy in East Africa. RefNo: CoBAMS-REC-2024-39
REFNo: SS2909ES

To examine the East African challenges in the context of the global political landscape of climate strategies and identify how success-criteria are derived from global dynamics, and what lessons from these local cases should be fed into global policy-making.,To identify and examine the ways in which Uganda and Tanzania have initiated local solutions to the charcoal and climate change crisis and how they can each harmonise their legal and policy framework change in a way that is responsive to their local realities while in tandem with global climate change and decarbonisation trends.,To understand the legal and policy frameworks governing the climate change, charcoal and decarbonisation dilemma in Uganda and Tanzania. ,To understand local processes of charcoal transition in Uganda and Tanzania in order to capture the impact of possible changes on livelihoods, food, nutrition and health as well as social stability, and relations among different social identity groups, where gender, youth, women and migration are particularly central. ,The main objective is to understand how global climate change mitigation policies (decarbonisation) condition charcoal politics and socio-economic dynamics in energy-stressed countries down to local levels, and how to manage conflicts.,
 Uganda 2024-08-12 10:56:54 2027-08-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
PATRICIA  ATUKUNDA
ID:
Staff Welfare Strategies and Performance of Healthcare Providers in Government -aided Health Facilities in Bushenyi District, Uganda
REFNo: SS2783ES

To find out the extent to which career growth strategy affects the performance of healthcare givers in government-aided health facilities in Bushenyi District, Uganda.,To determine the extent to which financial well-being strategy impacts the performance of healthcare workers in government-aided health facilities in Bushenyi District, Uganda,To establish the extent to which work-life balance strategy influences the performance of healthcare workers in government-aided health facilities in Bushenyi District, Uganda.,To assess the extent to which health and safety strategy influences the performance of healthcare givers in government-aided health facilities in Bushenyi District, Uganda.,To analyze how the well-being of staff influences the performance of healthcare givers in government-aided health facilities within Bushenyi District, Uganda.,
 Uganda 2024-08-12 10:55:47 2027-08-12 Social Science and Humanities Non-Clinical Trial Degree Award
CAROLINE NAKIDDE KAVUMA
ID:
Influence of Indigenous and Contemporary Early Years’ Education Pedagogy on Development of Children’s life-skills, Masaka District-Uganda
REFNo: SS2888ES

1.To establish the influence of indigenous pedagogy on the development of life skills among their children.
2.To investigate the influence of contemporary Early Years’ Education Pedagogy on the development of life skills among Baganda children.
3.To establish the influence of indigenous and contemporary EYE pedagogy on life skills development among children.
4.To examine the difference between the influence of IP and contemporary EYE pedagogy in development of life skills among Baganda children.

 Uganda 2024-08-06 18:26:29 2027-08-06 Social Science and Humanities Non-Clinical Trial Degree Award
Julia Mwesigwa Nanteza
ID:
Perceptions, attitudes and Information needs of Stakeholder, Health Worker, and Child Caregiver to guide introduction of the Malaria Vaccine in Uganda
REFNo: SS2895ES

1. Assess participants’ awareness of the MV, including identification of Malaria Vaccine information sources. 2. Ascertain the misconceptions, fears, and rumors from the public about the Malaria Vaccine. 3. Elicit participant concerns about side effects of the Malaria Vaccine. 4. Ascertain participant expectations for Malaria Vaccine efficacy and acceptability of continued bed net use with vaccinated children. 5. Assess caregivers’ acceptability of adhering to a four-dose vaccination schedule that extends into the second year of life and may involve new vaccination visits. 6. Identify health workers’ perceived challenges for client education, provision of a four-dose schedule, tracking dose delivery, and reporting. 7. Elicit national and subnational stakeholder views and recommendations for a successful introduction of the Malaria Vaccine, including recommendations about effective ways to link and integrate UNEPI and National Malaria Control Program (NMCP) activities to promote and provide the MV.
Uganda 2024-08-06 18:24:50 2027-08-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
NAKANWAGI JOSLYLINE LYDIA
ID:
A comparative analysis of adherence, retention in care, and viral suppression among PLHIV aged 50 and above and below 50 at Mulago ISS Clinic, Uganda.
REFNo: HS4587ES

To understand the psychosocial needs and challenges (stigma, social support, mental health and lifestyle adjustments faced by PLHIV aged 50 years and above attending Mulago ISS Clinic.,To determine the factors associated with adherence to ART, retention in care and viral suppression among people aged 50 years and above,o compare adherence to ART, retention in care and viral suppression of PLHIV aged 50 years and above and those below 50 years attending Mulago ISS clinic,To compare the cascade of care between people living with HIV aged 50 years and older and those below 50 years at Mulago ISS clinic in Uganda.,
 Uganda 2024-08-06 18:14:04 2027-08-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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