Victoria Ndyanabangi
ID: UNCST-2021-R012645
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IMPAACT 2024- Protocol Titled: Dose Finding, Safety and Tolerability Study of Daily Rifapentine Combined with Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age with and without HIV. DAIDS Study ID #38747,IND #171439
REFNo: HS6638ES
To determine weight-band dosing of a once-daily, 28-day regimen of isoniazid (INH) and rifapentine (RPT) (1HP) for the prevention of tuberculosis (TB) in children living with and without HIV.
Primary Objectives
Cohort 1 and Cohort 2
To determine the weight-band dosing of RPT taken as part of the 1HP regimen by evaluating:
⎯ PK RPT exposures among children with and without HIV
⎯ Safety and tolerability of the 1HP regimen among children with HIV while receiving twice-daily
DTG and children without HIV through 28 days of dosing
Cohort 2
• To evaluate the effect of RPT taken as part of the 1HP regimen on the PK of DTG
Secondary Objectives
Cohort 1 and Cohort 2
To evaluate the effect of covariates including age, weight, sex, ethnicity, nutritional status, and HIV-1 status on the PK of RPT taken as part of the 1HP regimen
• To evaluate the safety of the 1HP regimen through 24 weeks of follow-up
• To evaluate the palatability and acceptability of the 1HP regimen
• To evaluate adherence to the 1HP regimen
Cohort 2
• To evaluate the safety and tolerability of twice-daily DTG through 42 days among children with HIV who are receiving 1HP
• To evaluate virologic control (less than 200 copies/mL) at Day 42 among children taking a DTG-Based ARV treatment regimen co-administered with 1HP
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Uganda |
2026-03-30 12:54:54 |
2029-03-30 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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MAURICE ALEX MUHWEZI MURARI
ID: UNCST-2026-R023968
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Parenting Styles and Psychological Well-Being among Adolescents in Secondary Schools in Uganda: A Case of Kabale District in Western Uganda
REFNo: SS4926ES
1. To examine the relationship between parenting styles and adolescents’ psychological well-being in secondary schools in Kabale district.
2. To determine the most prevalent parenting styles among parents of adolescents in Kabale District.
3. To assess the relationship between parenting styles and adolescents’ self-esteem, and the mediating role of self-esteem in their psychological well-being.
4. To explore contextual and gender factors within Kabale District that influence the relationship between parenting styles, self-esteem, and psychological well-being of adolescents.
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Uganda |
2026-03-30 11:02:21 |
2029-03-30 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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ELETH NYIRANKUSI
ID: UNCST-2025-R021587
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PATIENTS’ WAITING TIME AND ASSOCIATED FACTORS AT UGANDA HEART INSTITUTE - A PHARMACIST’S PERSPECTIVE
REFNo: HS7234ES
General Objective
To examine patients’ waiting time and the associated factors influencing it from a pharmacist’s perspective at the Uganda Heart Institute.
Specific Objectives
1.To determine the average waiting time experienced by patients at the pharmacy unit of the Uganda Heart Institute.
2.To determine the institutional and operational factors contributing to prolonged pharmacy waiting times at the Uganda Heart Institute.
3.To explore pharmacists’ perspectives on the challenges and potential strategies for reducing patient waiting times.
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Uganda |
2026-03-30 10:59:36 |
2029-03-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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PIUS NANYANGA
ID: UNCST-2026-R024505
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THE EVOLUTION AND IMPACT OF DIGITAL
HEALTH INTERVENTIONS ON CLINICAL
WORKFLOWS, AND DECISION-MAKING AT
UGANDA CANCER INSITUTE
REFNo: HS7331ES
1.Assess the impact of digital health interventions on the efficiency of
clinical workflows at the UCI.
2. Examine how digital tools influence patient-provider interactions and
contribute to streamlined clinical processes at the UCI.
3.Examine the impact of electronic medical records and clinical decision
support systems on diagnostic accuracy and treatment planning among healthcare
providers at the UCI.
4.
Explore how access to digital health intervention tools and real-time
patient data supports evidence-based clinical decision-making among healthcare
professionals at the UCI
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Uganda |
2026-03-27 18:07:27 |
2029-03-27 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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John Baguma
ID: UNCST-2025-R017835
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Optimising protocols for domestic rearing of the palm weevil, Rhynchophorus phoenicis, in Uganda for value added food products and biofertilizer
REFNo: A684ES
To evaluate locally available organic waste materials as ingredients for optimizing rearing of R. phoenicis.
2. To assess the effect of artificial rearing on the nutritional value and organoleptic quality of R. phoenicis larvae.
3. To investigate the effects of incorporating palm weevil larvae into bread at different inclusion rates on microbial safety, nutritional qualities and sensory properties among palm weevil traditional consumers and non-consumers.
4. To investigate the use of R. phoenicis frass at different application rates as an organic biofertilizer in tomato production.
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Uganda |
2026-03-26 13:12:33 |
2029-03-26 |
Agricultural Sciences |
Non-Clinical Trial |
Degree Award |
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