Andrew Mujugira
ID: UNCST-2019-R000871
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HIV self-testing to increase testing of male partners in antenatal care in Uganda
REFNo: HS273ES
Primary objective: Determine whether secondary distribution of HIV self-testing to male partners of HIV-negative pregnant women increases the proportion of male partners who test for HIV compared to standard of care invitation letters for fast track testing.
Secondary objective: Evaluate whether HIV testing of male partners is associated with PrEP interest among HIV-negative women whose partner tests HIV-positive or
refuses testing.
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Uganda |
2018-12-11 |
2021-12-11 |
Medical and Health Sciences |
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Non-degree Award |
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Christine Wiltshire Sekaggya
ID: UNCST-2019-R000578
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A randomized, four-arm open label Phase IIb clinical trial to evaluate the Pharmacokinetics, Safety/tolerability and Efficacy of High Dose Rifampicin in TB-HIV co-infected patients on Efavirenz- or dolutegravir-based antiretroviral therapy (SAEFRIF)
REFNo: HS262ES
Primary objective
1. To determine the effect of a high dose of rifampicin (35 mg/kg orally) on the pharmacokinetics of first-line antiretroviral drugs (efavirenz and dolutegravir) in TB-HIV co-infected patients on TB treatment.
Secondary objectives
1. To investigate the safety/tolerability of a high dose of rifampicin in TB-HIV co-infected patients on TB treatment and first-line antiretroviral therapies.
2. To determine if TB-HIV co-infected patients on a high dose of rifampicin are more likely to have negative sputum cultures by the end of the intensive phase of TB treatment than patients on standard-dose rifampicin.
3. To explore the relationships between exposure to rifampicin, efavirenz and dolutegravir and the tolerability and efficacy of these drugs (Pharmacokinetic-Pharmacodynamic analysis).
|
Uganda |
2018-12-04 |
2021-12-04 |
Medical and Health Sciences |
|
Non-degree Award |
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Nurait Nambogo
ID:
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Mobile based application for appointment scheduling by health professionals
REFNo: HS251ES
•To assess the acceptability of MobiCare among health professionals and Patients/Clients.
•To pilot test MobiCare application at selected private health facilities in Mbarara municipality.
|
Uganda |
2018-12-04 |
2021-12-04 |
Medical and Health Sciences |
|
Non-degree Award |
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Mohammed Lamorde
ID: UNCST-2019-R001293
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Clinical Evaluation of the FilmArray Global Fever (GF) Panel
REFNo: HS265ES
To evaluate the clinical sensitivity and specificity of the assays comprising the FilmArray GF Panel when used to test whole blood specimens. It is hypothesized that the FilmArray GF Panel assays will detect clinically relevant levels of the pathogens included in the panel and give no false detections.
|
Nigeria |
2018-12-04 |
2021-12-04 |
Medical and Health Sciences |
|
Non-degree Award |
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Gloria Kirungi Kasozi Kasozi
ID:
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School-Based Sexual and Reproductive Health Services for Prevention of Adolescent Pregnancy in Hoima District, Uganda: a cluster randomized controlled trial
REFNo: HS247ES
1. To investigate the effect of School Based SRH services on occurrence of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda.
2. To evaluate the effect of School Based SRH services on sexual behavioral change for prevention of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda.
3. To analyze the effect of School Based SRH services on utilization of SRH services among school girls aged 15-19 years in Hoima District, Uganda.
4. To develop a School Based SRH services model for the prevention of adolescent pregnancy among school girls in Uganda
|
Uganda |
2018-11-30 |
2021-11-30 |
Medical and Health Sciences |
|
Degree Award |
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BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
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Molecular Epidemiological Surveillance of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum Parasite Population in Uganda
REFNo: HS271ES
(i) To determine prevalence of pfhrp2/3 gene deletions in P. falciparum parasites in Uganda.
(ii) To determine the distribution and geographical spread of pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda.
(iii) To determine the factors associated with pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda.
(iv) To determine diagnostic accuracy of malaria RDTs as compared to blood smear microscopy and PCR in settings where there are pfhrp2/pfhrp3 gene deletions in Uganda.
(v) To determine the multiplicity of infections in P. falciparum strains with pfhrp2/ pfhrp3 gene deletions in Uganda.
(vi) To determine the genetic diversity of P. falciparum Histidine-Rich Protein-2/3 genes in Parasite populations in Uganda.
(vii) To determine the origin and relatedness of pfhrp2/pfhrp3 gene deleted P.falciparum strains in Uganda.
|
Uganda |
2018-11-30 |
2021-11-30 |
Medical and Health Sciences |
|
Degree Award |
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Joseph Baluku B
ID: UNCST-2019-R000612
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One Dollar Incentive to Improve Tuberculosis Treatment Outcomes in a Programmatic Setting (ODITOPS trial)
REFNo: HS254ES
Primary objectives:
1. To determine the effect of a one dollar incentive on the TB treatment success rate of patients receiving TB treatment in rural hospitals of Uganda and Kenya.
2. To determine the effect of a one dollar incentive on TB loss to follow up rate of patients receiving TB treatment at rural hospitals in Uganda and Kenya
Secondary Objectives:
1. To determine the effect of a one dollar incentive on TB death rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya.
2. To evaluate the impact of a one dollar incentive on the TB treatment failure rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya
|
Uganda |
2018-11-13 |
2021-11-13 |
Medical and Health Sciences |
|
Non-degree Award |
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Hindum Lanyero
ID:
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Monitoring antibacterial use in children under five in rural Communities of northern Uganda.
REFNo: HS235ES
General Objective
To investigate antibacterial use among children under five in rural communities of northern Uganda and develop a method that can be used to validate the reported use.
Specific objectives
1. To determine antibacterial medicine use patterns as reported by caregivers of children under five who present with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study I).
2. To develop a chromatographic method for simultaneous identification of multiple antibacterial medicines in whole blood and urine spotted on filter paper (Sub-study II).
3. To establish the validity of self-reports in monitoring antibacterial use in children under five who are brought to health facilities with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study III)
|
Uganda |
2018-11-06 |
2021-11-06 |
Medical and Health Sciences |
|
Degree Award |
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Noeline Nakasujja
ID: UNCST-2019-R001428
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Pictures of ageing in Uganda: A pilot study to explore demography, healthy ageing phenotype and self-perception in a community of older people in Uganda
REFNo: SS246ES
Primary objective:
To determine the feasibility of combining demographic, phenotypic and artistic methods in understanding the picture of Ageing of community dwelling elderly individuals in Uganda.
Secondary objectives:
1) To assess the accuracy of age-reporting among older people (>60 years) living in a Wakiso District community and investigate how the accuracy of age-reporting is linked to health, capabilities, social status and residential circumstances.
2) To pilot test data collection tool for demographic assessment of older people in Uganda (culturally, linguistically, historically appropriate).
3) To pilot test data collection tools for phenotypic assessment of older people in Uganda (health status, frailty, cognition, capabilities, quality of life, co-morbidities including HIV, access to health and other services).
4) To assess feasibility and acceptability of undertaking cognitive testing using electronic tablets in older people living in a Wakiso District community.
5) To assess feasibility and acceptability of engaging older people through visual / performing arts activities.
6) To explore perceptions and attitudes to a community based participatory research in older people building on discussions/ interviews conducted in the context of 1-4 above.
7) To develop an exhibition of artwork by established artists and older people to express their perceptions of older age.
|
Uganda |
2018-11-06 |
2021-11-06 |
Social Science and Humanities |
|
Non-degree Award |
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Sarah Baliddawa
ID:
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Household members’ role and experiences during MDR-TB patients care at Mbarara Regional Referral Hospital, Uganda
REFNo: HS253ES
General objective:
To explore the roles and experiences of household members during the care of MDR-TB patients attending MRRH
Specific objectives:
To explore household members’ definition of MDR-TB
To explore the roles played by household members in care of MDR-TB patients
To explore the experiences of household members during care of MDR-TB patients
|
Uganda |
2018-11-06 |
2021-11-06 |
Medical and Health Sciences |
|
Degree Award |
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Nelson TING
ID:
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Genetic identity of elephant migrants across a forest-savanna mosaic of protected areas in Western Uganda
REFNo: NS72ES
To generate baseline knowledge of elephant movement, habitat use, and population size in and among the forested protected areas of western Uganda.
|
USA |
2018-10-30 |
2021-10-30 |
Natural Sciences |
|
Non-degree Award |
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Proscovia Nabunya
ID: UNCST-2019-R000970
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Social Support Systems and Community Resource Utilization for Children and Families Affected by HIV/AIDS in Uganda: A Stakeholder Perspectives Study.
REFNo: SS182ES
The overall aim of this research is to examine the social support systems and community resources available to orphaned children and families affected by HIV/AIDS in Southwestern Uganda. Specifically, utilizing a stakeholder perspective, the objectives of this research are: 1) To identify and examine the available social support systems and resources available to children and families affected by HIV; 2) To examine both family-level and community-level facilitators and barriers to access and utilization of community resources; and 3) To identify resource gaps and ways to improve social support systems for children and families affected by HIV. The long-term goal of this proposed research is to inform a developmental research grant application (R21), to test the feasibility, acceptability, and preliminary impact of a social support intervention that can address HIV-related stigma and social isolation, and its impact on the overall social and health wellbeing of orphaned children and their caregivers.
|
Uganda |
2018-10-30 |
2021-10-30 |
Social Science and Humanities |
|
Degree Award |
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James Ssuuna
ID:
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EFFECT OF HABITAT DISTURBANCE ON POPULATION DYNAMICS AND COMMUNITY STRUCTURE OF RODENTS IN MABIRA CENTRAL FOREST RESERVE, UGANDA
REFNo: NS73ES
1.Assess rodent composition, diversity, and habitat association in undisturbed forest, disturbed forest, and adjacent agricultural/fallow fields in Mabira central forest reserve(MCFR).
2.Determine the influence of habitat structure/disturbance, and seasonal changes on recruitment, and survival of the dominant rodent species in MCFR.
3.Determine the effect of habitat structure/disturbance, and rainfall patterns on the breeding/reproduction patterns of the dominant rodent species in MCFR.
4.Investigate the movement and ranging patterns of the dominant rodent species in MCFR.
|
Uganda |
2018-10-30 |
2021-10-30 |
Natural Sciences |
|
Degree Award |
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Sadic Waswa Babyesiza Waswa
ID: UNCST-2019-R000849
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PREVALENCE AND DIVERSITY OF HEAMOFLAGELLATES AND FILARIAL WORMS IN RODENTS AND SHREWS INHABITING A DEGRADATION GRADIENT IN MABIRA FOREST RESERVE
REFNo: NS54ES
•Investigate the rodent and shrew species composition and seasonal fluctuations in their population structures along a habitat degradation gradient in MCFR
•Identify and describe heamoflagellates and filarial worms in rodents and shrews using their morphological, morphometric and molecular characteristics.
•Describe diversity, prevalence, distribution and public health importance of heamoflagellates and filarial worms identified in rodents and shrews of MCFR.
•Investigate factors that affect prevalence and distribution of heamoflagellates and filarial worms in rodents and shrews in MCFR.
•Investigate the relationship between rodent borne zoonotics prevailing with in adjacent communities Vs heamoflagellates and filarial worms identified in rodents and shrews.
|
Uganda |
2018-10-30 |
2021-10-30 |
Natural Sciences |
|
Degree Award |
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Cathryn Townsend Megan
ID:
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Human Generosity Among the Ik
REFNo: SS201ES
Based on two empirical studies, conducted in WEIRD (Western, educated, industrialized, rich, and democratic) populations in the USA and in the Netherlands, we hypothesize that perceived fitness interdependence (PFI) is the primary psychological motivator of altruistic or generous actions in human cooperation and that PFI varies according to both the situational and relational contexts of human interactions. This existing empirical evidence needs corroboration in diverse cultural and ecological conditions in order to support the universal value of the hypothesis. The current study will serve as a pilot to determine whether the PFI scales that we have developed would be adaptable to non-WEIRD populations.
|
UK |
2018-10-30 |
2021-10-30 |
Social Science and Humanities |
|
Non-degree Award |
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Irene Ayakaka
ID:
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A Stakeholder analysis of chronic Lung Disease (CLD) management in Uganda
REFNo: HS232ES
Objectives of the research project:
Overall Aim
The overall goal of the project which this study aims to inform, is to improve the management of CLD in Uganda. This study seeks to analyze the current CLD policy in Uganda, identify gaps in the policy formulation that may translate to gaps in policy implementation. The aim is to generate evidence that can be used to develop targeted, informed interventions to strengthen CLD programmatic management in this setting. Specifically, the study proposes to achieve this through:
1. Stakeholder analysis and mapping to characterize the actors and networks, their linkages and relative influence and how this affects CLD policy in Uganda.
2. An exploration of the policies for the management and implementation of policies to address CLD in the public health system in Uganda.
Stakeholders in this study will be limited to at least one representative from; the Uganda ministry of health; from academia; funders and MOH implementing partners and from civil society to help understand and describe the policy context and to clinical heads from Kampala city based health facilities as representatives to help describe and understand the clinical context.
|
Uganda |
2018-10-30 |
2021-10-30 |
Medical and Health Sciences |
|
Degree Award |
|
Stephanie Sweet
ID:
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Geospatial Analytics for Improved Tax Compliance
REFNo: SS242ES
This research will attempt to analyze tax evasion and estimate the compliance tax gap (difference between potential and actual revenue) through the use of geospatial analytics in Uganda.
|
USA |
2018-10-30 |
2021-10-30 |
Social Science and Humanities |
|
Degree Award |
|
Shai Andre Divon André
ID:
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Community Based Policing: Uganda Case Study (ICT4COP)
REFNo: SS231ES
The Uganda case study provides an insight into African perspectives on COP. The overarching objective of the study is to explore the influence and impact of the Ugandan approach to COP. As such the research in Uganda will focus on: police training, application of policing/community policing and impacts of policing on communities. Parts of the research in Uganda may link to the South Sudan case study including through the impact of Uganda’s approach to policing on South Sudan through police training.
The focus on the training component will mainly observe the efforts of the Government of Uganda to assist the crisis in South Sudan through police training, but also on the Ugandan concept of COP and the official structures for the implementation of COP. The focus on application of policing/community policing will explore police-community relations in selected areas in Northern Uganda. This component will also include an element bridging into the South Sudan case study by exploring the dynamics between Ugandan host communities and settled refuges from South Sudan, concentrating on police-community relations and the unique challenges that Ugandan police faces in such contexts. The impacts of policing on communities element will explore how both the police and communities collaborate and how has this collaboration affects a range of human security issues in contexts.
To achieve the overarching objective the research will revolves around the following sub-objectives:
1. To analyze COP applied in Northern Uganda
2. To investigate COP applied in a variety of socio-cultural contexts in Northern Uganda
3. To understand COP training provided by Uganda to other African nations
|
Norway |
2018-10-30 |
2021-10-30 |
Social Science and Humanities |
|
Non-degree Award |
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Margaret Lubwama
ID: UNCST-2019-R000636
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Knowledge, attitudes and perceptions about antibiotic use and resistance among final year medical and pharmacy students- a step toward antimicrobial stewardship
REFNo: HS248ES
Overall Goal of the Project
To increase the awareness among the public and various stakeholders (College Principle, curriculum designers, heads of departments, Ministry of Health (MOH)) of the need of antimicrobial stewardship programmes within the curriculum of final year undergraduate medical students with the ultimate aim of antimicrobial stewardship being introduced in the regional hospitals where these students will be posted
Specific Objective One
To determine the level of competency of final year medical and pharmacy students of the Makerere University and Mount Kenya University Colleges of Health Science to prescribe antibiotics appropriately
Specific Objective Two
To review and report on the findings of this study to various stakeholders in meetings, conferences within the region and to publish the findings from this study in a peer reviewed journal within the final year of the project
|
Uganda |
2018-10-30 |
2021-10-30 |
Medical and Health Sciences |
|
Non-degree Award |
|
Violet Korutaro
ID: UNCST-2019-R000618
|
Baylor-IMPAACT-004: IMPAACT 2009; Protocol titled: Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for Primary HIV Prevention during Pregnancy and Postpartum in Adolescents and Young Women and their Infants Ver
REFNo: HS252ES
a) Primary Objective for PK Component
• To determine the concentration of Tenofovir diphosphate (TDF-DP) associated with adequate adherence to FTC/TDF among women observed ingesting daily oral Prep during pregnancy and postpartum.
b) Secondary Objective for PK Component
• To compare TFV-DP concentrations observed in pregnant and postpartum women
c) Primary Objectives for PrEP Comparison Component
• To characterise PrEP adherence among HIV- uninfected young women during pregnancy and for twenty-six weeks postpartum, when provided with enhanced adherence support through mobile technology and counselling based on observed drug levels.
• To assess the safety of FTC/TDF for PrEP during pregnancy and postpartum by comparing pregnancy outcomes and maternal and infant safety between cohorts.
d) Other objectives for PrEP Comparison Component
• To identify individual, social and structural barriers and facilitators to PrEP uptake during pregnancy, and to adherence during pregnancy and postpartum.
• To compare reported sexual risk behaviours and incidence of sexually transmitted infection, among women who initiate PrEP during pregnancy versus women who decline PrEP.
• To compare antiretroviral drug resistance among women and infants who acquires HIV and without exposure to FTC/TDF for PrEP, including whether resistance was transmitted or acquired at time of transmission.
• To compare bone density in women who initiated PrEP during pregnancy and women who decline PrEP.
e) Exploratory Objective for PrEP Comparison Component
• To describe the composition of and changes in the maternal vaginal and gut microbiome and infant gut microbiome according to PrEP exposure.
|
Uganda |
2018-10-30 |
2021-10-30 |
Medical and Health Sciences |
|
Non-degree Award |
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