Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred Ssewamala
ID: UNCST-2020-R014060
Bridges R2: Evaluating the Long-term Impact of a Family Economic Empowerment Intervention on HIV Risk Prevention and Care Continuum Outcomes among Orphaned Youth Transitioning to Young Adulthood
REFNo: SS1832ES

Aim 1. Examine the long-term impact of Bridges on: HIV prevalence (measured via participant’s HIV status) (Primary outcome); and b) Explore in secondary analyses the long-term impact of Bridges on key developmental and behavioral outcomes (e.g., mental health, alcohol, and drug misuse). Aim 2. Elucidate the long-term effects of Bridges on potential mechanisms of change, including a) economic stability, viral suppression (for ALHIV); PrEP use (for HIV negative adolescents), medical male circumcision (for boys); and b) young adult transitions. Aim 3: Qualitatively investigate participants’ experiences with Bridges that may have influenced engagement with the program, sexual risk-taking decisions, financial behaviors; experiences with developmental transitions; and perceptions on program sustainability. Aim 4: To assess the long-term costs and benefits of Bridges using formal economic evaluation.
Uganda 2023-06-20 10:23:08 2026-06-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aloysius Mubuuke Gonzaga
ID: UNCST-2019-R000969
Development of a mentorship framework guide to promote the acquisition of interprofessional education (IPE) and collaborative practice competencies during undergraduate training
REFNo: HS2920ES

To conduct a situational analysis among faculty and students on mentorship in relation to the learning of IPE competencies. To develop a mentorship guide framework for promoting the learning of IPE competences To validate the mentorship guide framework developed through a Delphi process.
Uganda 2023-06-20 10:12:20 2026-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
IMPROVING HIV CARE ENGAGEMENT AMONG ADOLESCENT GIRLS AND YOUNG WOMEN LIVING IN WAKISO DISTRICT THROUGH REDUCTIONS IN MALE PARTNER ALCOHOL USE AND INTIMATE PARTNER VIOLENCE RISK: THE KISOBOKA MUKWANO INTERVENTION.
REFNo: HS2905ES

Objective 1: Adapt and refine the behavioral components of a brief MI-based alcohol intervention to develop the proposed Kisoboka Mukwano (“It is possible, my love!”) intervention– a brief couples-based intervention using motivational interviewing and peer navigation approaches to target intimate partner violence, alcohol use, and HIV care engagement.

Objective 2: Assess the safety of the Kisoboka Mukwano intervention.

Objective 3: Assess the acceptability and feasibility of the Kisoboka Mukwano intervention.

Objective 4: Assess the preliminary efficacy of the Kisoboka Mukwano intervention, randomizing couples to the Kisoboka Mukwano intervention (n=25 couples) or the control (n=25 couples) arm.

Uganda 2023-06-20 10:03:15 2026-06-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty Mwesigwa
ID: UNCST-2020-R014667
SABIN-002: A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate Safety, Tolerability, and Immune Responses of an Investigational Monovalent Chimpanzee Adenoviral-Vectored Marburg Virus Vaccine in Healthy Adults
REFNo: HS2838ES

To evaluate the safety and tolerability of
cAd3-Marburg vaccine
Uganda 2023-06-14 11:06:46 2026-06-14 Medical and Health Sciences Clinical Trial Non-degree Award
Roda Siad
ID:
Exploring the implications of blockchain and other emerging technologies on refugee governance
REFNo: SS1622ES

My research will examine how blockchain and other emerging technologies are conceptualized, deployed, and operationalized within refugee settings. Using Kenya and Uganda as sites of analysis, the thesis will ask the following research questions: 1) How are blockchain and other technologies shaping the governance of refugees? 2) How do refugees engage with blockchain and other emerging technologies in their everyday lives? 3) What is at stake in these technological systems and practices when applied within humanitarian interventions? The specific objectives that follow from these research questions are to: a) assess what can be learned from the deployment of blockchain and other emerging technologies b) examine how refugees understand and frame their engagement with such technologies and c) understand the visions and imaginaries of tech developers and humanitarian organizations and how they define their collaborative work. This research also considers how different actors (tech industry workers, corporate funders, UNHCR staff and refugees) understand, contribute to, and shape the discourse around blockchain and other technologies in humanitarian settings. This research will use several data collection methods based on empirical fieldwork in camp and non-camp settings and discourse analysis to capture the diverse perspectives of tech industry workers, corporate funders, UNHCR innovation staff, camp staff and refugees.
Canada 2023-06-13 8:27:14 2026-06-13 Social Science and Humanities Non-Clinical Trial Degree Award
Hilde Bras Agnes José
ID:
White Sisters, Nursing Practices, and Reproductive Health in East Africa, 1890-present
REFNo: SS1371ES

This research project comprises two sub-projects carried out by a senior researcher (PI – Prof. Dr. Hilde Bras who holds the Aletta Jacobs Chair in Economic and Social History, with special attention to Global Demography and Health at the University of Groningen), and a PhD student (Ivana Zecevic, MA), both working at the Department of History of the University of Groningen, Chair Group of Economic and Social History (ESH).
The project aims to contribute to the debate taking place among economic and social historians, historical demographers and medical historians about the historical legacies of colonialism for contemporary global health, in particular in sub-Saharan Africa (Doyle, 2013; Walters, 2008). What was the effect of the colonial presence, and of female missionaries in particular, on (reproductive) health in Africa? To what extent did missionary health care lead to changes in fertility (number of children per woman), maternal mortality, venereal diseases, and infant and child mortality and morbidity? Research within this debate has focused mainly on colonial state medicine and on doctors (Iliffe, 1998) and hardly on the role of the mission (but cf. Doyle et al., 2020; Jennings, 2006), mission nurses, and nursing care. Moreover the present project focuses on missionary nursing practices in relation to extant indigenous midwifery and nursing practices and explicitly foregrounds the relationship between the two.The overarching research question is: What are the nursing practices (related to maternal and child care) of missionary nurses (MSOLA), indigenous nurses, and missionary doctors and how are they related to fertility, morality, child and maternal health in East Africa, 1890-present?
Netherlands 2023-06-13 8:15:29 2026-06-13 Social Science and Humanities Non-Clinical Trial Degree Award
Eric Katagirya
ID: UNCST-2021-R012813
Targeting non-coding RNAs as host-directed drug therapy for tuberculosis
REFNo: HS2679ES

To predict and identify target genes of ncRNAs validated in Aim 1 via computational approaches and dual luciferase reporter assay system.,To functionally validate our identified ncRNAs in ex vivo Mtb-infected PBMCs isolated from healthy volunteers using synthetic antagomirs.,
Uganda 2023-06-13 8:13:42 2026-06-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JULIET NAKKU EVELYN MUBIRU
ID:
ASSESSMENT OF THE EXTENT OF INTEGRATION OF MENTAL HEALTH SERVICES INTO PRIMARY HEALTHCARE, COMMUNITY AND SCHOOLS. A NATIONAL STUDY Refno: (SPH-2023-417)
REFNo: HS2911ES

To assess the role of alternative forms of care (traditional healers, churches and mosques) in integrating Mental Health in PHC.,To assess the knowledge, attitude and practice of teachers, learners, families and community resource persons in mental health care.,To describe the forms of community mental health services offered in the community,To explore the challenges to, opportunities and recommendations for the integration of mental health into primary health care and in schools.,2. To establish the availability, access and quality of mental health services.,To assess patterns of common mental disorders.,To assess the extent of integration of mental health into primary healthcare, Community and Schools in Uganda. ,
Uganda 2023-06-13 11:59:34 2026-06-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Georgina Manyuru Angela
ID:
A Review of the Evaluation Education Programme offered at Uganda Management Institute
REFNo: SS1807ES

i) To contribute to the improvement of M&E programmes/courses offered at UMI, and

ii) To understand the challenges faced by UMI in its efforts to provide comprehensive M&E learning.

Uganda 2023-06-13 11:57:28 2026-06-13 Social Science and Humanities Non-Clinical Trial Degree Award
Kyabarongo Benon
ID:
CORPORATE GOVERNANCE AND FINANCIAL PERFORMANCE OF SAVINGS AND CREDIT CO-OPERATIVE SOCIETIES IN UNGANDA
REFNo: SS1746ES

iii. To analyze the effect of board risk management on financial performance of selected SACCOS in Kiruhura District.,ii. To analyze the effect of board assurance on financial performance of selected SACCOs in Kiruhura District. ,i. To examine the effect of board accountability on financial performance of selected SACCOs in Kiruhura District.,The purpose of this study is to investigate the effect of corporate governance on financial performance of SACCOs in Kiruhura District, Uganda,
Uganda 2023-06-13 11:49:07 2026-06-13 Social Science and Humanities Non-Clinical Trial Degree Award
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