Lian Thomas Francessca
ID: UNCST-2022-R010668
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Baseline studies for characterising the area-specific context for the control of Taenia solium infections in northern Uganda
REFNo: A263ES
1. To estimate the prevalence of porcine cysticercosis (PCC) and pig gastrointestinal parasites in Kitgum, Lamwo, Agago, and Pader districts in northern Uganda.
2. To characterise porcine cysticercosis risk factors in the four districts to support the design of interventions.
3. To understand the socioeconomic, cultural, and policy context in which T. solium control will be undertaken in Northern Uganda.
4. To identify stakeholders their roles, relationships, power dynamics, and motivations in the control of Taenia solium infections using the net-mapping methodology.
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UK |
2023-09-05 13:59:55 |
2026-09-05 |
Agricultural Sciences |
Non-Clinical Trial |
Non-degree Award |
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Moses Joloba Lutaakome
ID: UNCST-2022-R011558
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Bacterial and Host Heterogeneity in TB latency, persistence and progression
REFNo: HS3039ES
Objective 1: Determine the extent to which household transmission is responsible for co-prevalent and incident TB cases caused by Mtb strains that are genetically distinct from those isolated from the index cases within the same household.
Objective 2: Investigate the in vitro immune phenotype of transmitted versus not-transmitted Mtb strains in households stratifying for HIV status.
Objective 3: Characterize the innate macrophage response to high and low transmission strains and the T-cell response in persons with known household exposure to high and low transmission isolates and the impact of HIV infection.
Objective 4: Identify the component of Mtb genes that aid in bacterial survival in aerosols.
Objective 5: Investigate the bacterial factors underlying divergence in the host response to high and low transmission isolates.
Objective 6: Determine the impact of Mtb strain phenotype (eg Mtb-HT v Mtb-LT) and host heterogeneity (risk of progression signatures, co-morbidities) on:
6.1. The distribution of stages of Mtb infection and disease in exposed HHC: the proportion of MTBI that express PREDICT29, a risk of progression signature; ACS-COR, an inflammatory signature; subclinical TB and active TB.
6.2. The risk and timing of progression from MTBI to TB.
6.3. The extent and nature (eg cavitation) of pulmonary disease in TB index cases; the duration of inflammation; and the consequent short- and long-term impairment in pulmonary function.
These studies could permit the development of individualized approaches based on the host and the bacterium to diagnosis, targeting of preventive therapy, and treatment of active TB.
Objective 7: Profile the lung milieu among individuals infected with either Mtb-HT or Mtb-LT in order to identify immune mediators associated with transmission heterogeneity.
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Uganda |
2023-08-30 16:32:02 |
2026-08-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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David Aziku
ID: UNCST-2023-R007595
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Exploring how climate change impacts on girls’ lives, with a focus on education.
REFNo: SS1917ES
3. Determine the extent to which education – and/or other sources of information – inform girls’ (and their households’) decision-making on coping strategies and adaptative capacities.,2. Understand how climate impacts shape girls’ and households’ decision-making, coping strategies and adaptive capacities, including how girls’ education is impacted in these processes.,1. Establish the climate-induced impacts experienced by girls, their households, and their communities, with reference to how these have changed over time, whether girls think they can be adapted to and how the climate may impact on the girls’ education. ,We aim to provide evidence to inform Plan International’s wider work and agenda on climate change and education, as noted above. We propose to utilise existing evidence from our Real Choices, Real Lives study and undertake additional data collection that specifically explores the impacts of climate change (and in doing so explores adaptation, losses and damages).,
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Uganda |
2023-08-30 16:25:00 |
2026-08-30 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Diana Nakitto Kesi
ID:
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The burden of medication errors and the barriers and facilitators to medication error reporting in Uganda. A prospective observational mixed method study
REFNo: HS3085ES
5. To explore patients’ perspectives on medication errors and medication error reporting.,4. To describe the barriers and facilitators to medication error reporting among health workers ,3. To assess the knowledge and attitude of health care workers on medication errors and medication error reporting.,2. To identify the medicines and morbidities associated with medication errors in health facilities,1. To determine the incidence of medication errors in the selected health facilities.,
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Uganda |
2023-08-30 16:14:41 |
2026-08-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Sofie Bjerregaard Budhoo
ID: UNCST-2022-R010093
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After Access to Justice: Exploring the development of local social dynamics and perceptions of justice in Northern Uganda after the International Criminal Court's (ICC's) Access to Justice Project
REFNo: SS1877ES
2. How will local perceptions of the ICC justice process, particularly in relation to reparations, develop over time after the end of the AJP?,1. What local patterns of behaviour and social dynamics will unfold over time in relation to the ICC justice process, particularly in relation to reparations, after the AJP has ended?,
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Denmark |
2023-08-30 16:11:54 |
2026-08-30 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Felix Jurua
ID: UNCST-2022-R009182
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Pilot study of the Dried Tube Specimen(DTS)stability in Uganda.
REFNo: HS2763ES
To compare Asante reading of DTS prepared with a preservative (trehalose) vs vehicle after a variable period of time (1-3 months) in 20 locations.
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Uganda |
2023-08-30 16:07:09 |
2026-08-30 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Edrisa Mutebi Ibrahim
ID:
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Safety of JNK61 in Healthy Human Volunteers.
REFNo: HS2474ES
To determine the effect of JNK61 on the blood sugar levels in healthy human volunteers.,To determine the safety of JNK61 in healthy human volunteers,
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Uganda |
2023-08-30 16:05:54 |
2026-08-30 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Kevin Mugisa Micheal
ID:
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MALE INVOLVEMENT IN CONTRACEPTION NEGOTIATION AMONGST BODA-BODA RIDERS IN KAMPALA, UGANDA.
REFNo: HS3108ES
1.To examine the prevalence of boda-boda men who are initiating contraception negotiations with their sexual partners.
2.To examine the proportion of boda-boda men who are involved in contraception negotiation with their sexual partners.
3.To analyze factors associated with contraception negotiation amongst Boda-Boda riders with their sexual partners.
4.To examine the contraception use frequency amongst boda-boda riders with their sexual partners.
5.To examine contraception methods agreements amongst boda-boda riders with their sexual partners.
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Uganda |
2023-08-29 15:14:53 |
2026-08-29 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Winfred Nazziwa
ID: UNCST-2019-R000003
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Alternative clinical Trial Designs and Methods :The Ethics of Controlled Human Infection studies in Low Resource Settings
REFNo: SS1925ES
The main objective of the study is to examine the ethics, perceptions and acceptability of controlled human infection studies in low resource settings. The specific objectives include;
1. To explore the perceptions of key research stakeholders on the conduct and oversight of controlled human infection studies.
2. To determine general public’s views about acceptability of controlled human infection studies.
3. To explore the experiences of research participants who have participated in a controlled human infection study in Uganda.
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Uganda |
2023-08-25 8:44:58 |
2026-08-25 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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OLIVIE NAMUJU CAROLYNE
ID:
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LENGTH OF IN-HOSPITAL STAY, MORTALITY DUE TO HIV-ASSOCIATED CRYPTOCOCCAL MENINGITIS, AND ASSOCIATED FACTORS IN THE ERA OF NEW TREATMENT GUIDELINES AT TERTIARY HEALTH FACILITIES IN UGANDA- A CROSS-SECTIONAL STUDY
REFNo: HS3047ES
Specific Objectives
I. To determine the proportionate contribution of hospitalized patients with HIV-CM on the new guidelines of HIV-CM treatment to all-cause HIV-related mortality.
II. To determine the mean length of hospitalization among HIV-CM after initiation on new guidelines of the HIV-CM treatment regimen at discharge.
III. To determine the factors associated with mortality among the patients on the new guidelines of the HIV-CM treatment regimen
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Uganda |
2023-08-25 8:27:19 |
2026-08-25 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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