Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Prossy Bibangambah Kyasimire
ID: UNCST-2024-R002215
Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
REFNo: HS5418ES

Aim 1: Perform CCTA -based segmentation of PCAT (1a) and compare the density between PWH and PWOH (1b) in Uganda.
Aim 2: Extract PCAT radiomics features (2a) and compare differences in PCAT radiomics signatures between PWH and PWOH (2b) in Uganda.
Aim 3: Determine whether the PCAT density (from Aim 1) or radiomics signatures (from Aim 2) improve the performance of cardiovascular risk prediction in Uganda.
Uganda 2025-02-07 17:38:35 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
Bone Health in Older Ugandan Women with and without HIV
REFNo: HS5455ES

To examine bone mineral density (BMD) and body composition in older (peri-menopausal and postmenopausal) African women who are living with HIV and taking antiretroviral therapy (ART) drugs compared to women representing similar age and background characteristics who are HIV-negative.
Uganda 2025-02-07 17:30:13 2028-02-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jennifer Serwanga
ID: UNCST-2024-R002056
Universal Protocol for Standardizing emerging Assays and Advancing vaccine Immunogenicity Assessments for Emerging and Re-emerging viral Threats through UVRI’S Partnership with the coalition for Epidemic Preparedness Innovations (CEPI)’s Centralized Clinical Laboratory Network (CLN).
REFNo: HS5330ES

To standardize and accelerate the evaluation of vaccine candidates against CEPI priority diseases, including Ebola, Marburg, Lassa, Nipah, Rift Valley Fever, SARS-CoV-2, MPOX and unidentified emerging threats, by leveraging UVRI's infrastructure and expertise.

To contribute to accelerated global vaccine development and licensure by ensuring rapid, accurate, and consistent data generation, while enhancing regional outbreak preparedness through technology transfer and capacity building.
Uganda 2025-02-04 8:15:09 2028-02-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald  Bahati
ID: UNCST-2023-R007024
NAVIGATING MENTAL HEALTH IN SCHOOLS PROJECT: EDUCATORS’ MENTAL HEALTH LITERACY CONCERNING ANXIETY, DEPRESSION AND NON-SUICIDAL SELF INJURY
REFNo: HS5381ES

To ascertain the educators’ confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,3. To assess educators’ level of mental health literacy about non-suicidal self-injury among school aged adolescents in selected schools in southwestern Uganda.,2. To assess educators’ level of mental health literacy about depression among school aged adolescents in selected schools in southwestern Uganda,1. To assess educators’ level of mental health literacy about anxiety among school aged adolescents in selected schools in southwestern Uganda,To assess educator’s mental health literacy about anxiety, depression and non-suicidal self-injury and their confidence in providing help to affected school aged adolescents in selected schools in southwestern Uganda.,
Uganda 2025-01-31 8:00:54 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Shevin  Jacob Thomas
ID: UNCST-2022-R010715
The Sub-Saharan Africa ConsorTium for the Advancement of Innovative Research and Care in Sepsis (STAIRS) Cohort Study: A prospective multi-country network cohort of hospitalized sepsis patients
REFNo: HS5205ES

1. Describe the cohort’s epidemiologic, sociodemographic, clinical and management characteristics and to identify risk factors for disease severity and outcomes. 2. Characterize etiologic (and antimicrobial resistance patterns when relevant) and host response profiles and to evaluate their potential associations with clinical presentation, disease severity and outcome. 3. Determine the performance characteristics of innovative sepsis diagnostic platforms for pathogen identification, host response profiling and risk stratification in comparison with diagnostic testing available for usual care (including blood culture and existing sepsis scores).
USA 2025-01-31 7:59:00 2028-01-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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