Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Confidence  Nkurunungi Asiimwe
ID: UNCST-2024-R015200
Parent Alcohol Use, Harsh Parenting,Adolescent Alcohol Use and Mental Illness among Adolescents in Kabale District, Southwestern Uganda
REFNo: SS4070ES

1) To examine the association between parent alcohol use and harsh parenting.
2) To determine the association between parent alcohol use and adolescent mental illness.
3) To examine the association between harsh parenting and adolescent mental illness.
4) To find out the association between adolescent alcohol use and adolescent mental illness.
5) To find out whether adolescent alcohol use mediates the association between parent alcohol use, harsh parenting and mental illness.
6) To explore experiences of parents, teachers and opinion leaders in regard to parent alcohol use, harsh parenting, adolescent alcohol use and mental illness.

Uganda 2025-07-22 15:41:23 2028-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Marion Birungi
ID: UNCST-2024-R016519
Barriers, Facilitators and Solutions towards Sustainability of Antimicrobial Stewardship Interventions in Selected Ugandan Hospitals. A multiple-methods study
REFNo: SS3741ES

1. To determine the AMS interventions implemented in six selected hospitals in Eastern and Central Uganda.
2. To explore barriers and facilitators of sustainability of AMS interventions in six selected hospitals in Eastern and Central Uganda.
3. To examine how attributes that contribute to sustainability were conceptualized and embedded in the implementation of AMS interventions in six selected hospitals in Eastern and Central Uganda.
4. To assess the sustainability capacity for AMS interventions in six selected hospitals in Eastern and Central Uganda.

Uganda 2025-07-22 15:25:28 2028-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
EVALUATING HIV EARLY INFANT DIAGNOSIS PERFORMANCE FOR THE ALINITY M HIV-1 ASSAY
REFNo: HS6246ES

1. The primary objective of this protocol is to evaluate the concordance of the Alinity m HIV-1 assay with the cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 for early infant diagnosis. The percent agreement will be assessed.
2. The secondary objective is to validate the use of the investigational Alinity m DBS EID Supplement to Alinity m HIV-1 assay using. Specifically, the percent agreement compared to cobas HIV-1/HIV-2 Qualitative nucleic acid test for use on the cobas 6800/8800 will be determined.

Uganda 2025-07-22 15:23:01 2028-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
bwesigye thaddeus
ID: UNCST-2025-R017892
Anti-cancer activity of selected medicinal plant species in Kigezi Sub Region of Uganda used by Herbalists
REFNo: NS953ES

i. Identify the medicinal plants species in Kigezi used by herbalists for cancer management in order to document them. ii. Evaluate the effect of the medicinal plants’ extracts used by herbalists on human cancer cell lines in order to determine their cytotoxicity. iii. Evaluate the isolated phytochemical compounds from the anticancer medicinal plant extracts for antioxidant potential to determine their cytotoxic effect on human cancer cell lines. iv. Investigate the cytotoxic effect of phytochemical compounds from the anticancer medicinal plants on human cell lines so as to determine their mechanism of cell death.
Uganda 2025-07-22 15:08:53 2028-07-22 Natural Sciences Non-Clinical Trial Degree Award
LIVINGSTONE MAKANGA KYEGOMBE
ID: UNCST-2024-R015296
Maternal and perinatal death surveillance and response: Analysis of the processes, factors and challenges of implementation in refugee-hosting districts of west Nile, Uganda
REFNo: HS5996ES

3) To explore the perceptions of stakeholders (including refugees and nationals) on the processes and challenges of implementing MPDSR in refugee-hosting districts of the west Nile region. ,2) To assess factors that influence the implementation of maternal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile.,1) To assess the processes of implementation of maternal and perinatal death surveillance and response in Adjumani and Yumbe refugee-hosting districts of west Nile. ,To investigate the processes, factors, and challenges of implementation of maternal and perinatal death surveillance and response (MPDSR) in refugee-hosting districts of west -Nile,
Uganda 2025-07-22 15:07:21 2028-07-22 Medical and Health Sciences Non-Clinical Trial Degree Award
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