Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Patrice Mawa Akusa
ID: UNCST-2024-R015843
Establishing Model Biobanks of Patient Leftover Samples from Routine Healthcare Provision in Kenya and Uganda: a pilot implementation in real-world environment (SAMPLE Study)
REFNo: HS7318ES

(1) To adapt, optimise and co-create effective implementation strategies for biobanking of leftover samples from routine care, using a federated model in Kenya and a centralized model in Uganda.
(2) To implement the optimized models of biobanking by selected healthcare facilities with the goal of enhancing quality sample collection, storage, and implementation of data systems to manage the biobanks, while creating stakeholder awareness and undertaking training of laboratory personnel and continuous monitoring of processes through evidence-based practices for a follow up period of 12 months.
(3) To determine whether the implementation strategies for the model biobanks influence implementation-level outcomes (e.g., acceptability, adoption, appropriateness, feasibility, fidelity, and sustainability).
(4) To determine whether the model biobanks are effective in achieving (i) sufficient sample quantities and ii) sample quality by type of sample.
(5) To estimate the cost and cost-effectiveness of operating the model biobanks for one year.
(6) To strengthen the capacity of researchers and promote the use of biobanks through pilot research projects based on the samples collected in the biobanks.

Uganda 2026-08-17 0:02:19 2029-08-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WILSON ETOLU JOHN
ID: UNCST-2025-R023102
Teso Community Outreach for Awareness and Control of Hypertension and Diabetes (T-COACH)
REFNo: HS7713ES

1. To train and equip VHTs in the Teso sub region to conduct community-level health education and screening for elevated blood pressure and random blood sugar among adults
2. To implement a community-based screening and referral system using VHTs for timely identification of individuals with suspected or confirmed hypertension or diabetes and facilitate linkage to health facilities.
3. To support VHTs to monitor BP and blood glucose levels among patients diagnosed with hypertension or diabetes and facilitate medication refills in coordination with health facilities.
4. To evaluate the change in community screening rates, detection rates, knowledge and awareness level and control levels of hypertension and diabetes after 6 months of implementation through pre- and post-intervention surveys.
5. To document the feasibility, acceptability, and challenges of integrating hypertension and diabetes care into the VHT mandate to inform future scale-up and policy adoption.

Uganda 2026-08-14 19:31:10 2029-08-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josephine Nabukenya
ID: UNCST-2026-R024846
NIAMR: Developing and Evaluating a National Interoperable Integrated Digital Data Capture and Sharing Platform for Enhanced Detection and Monitoring of Antimicrobial Resistance to Improve One Health AMR Surveillance and Management in Uganda
REFNo: HS7964ES

1. Assess existing AMR surveillance and data systems in Uganda. 2. Co-design and develop an integrated interoperable digital AMR surveillance platform. 3. Pilot and evaluate the platform across One Health sectors. 4. Strengthen AMR data sharing, analysis and use for decision-making. 5. Generate evidence to support national scale-up and sustainability of integrated AMR surveillance systems.
Uganda 2026-08-14 19:29:34 2029-08-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
Genomic profiling of plasmodium falciparum diversity and drug resistance markers and their effects on malaria recurrence among Ugandan children on dihydroartemisinin-piperaquine for post-discharge malaria chemoprevention after severe malaria anaemia
REFNo: HS8267ES

Objectives:

Main Objective
To investigate the role of P. falciparum genetic diversity and antimalarial drug-resistance markers in malaria recurrence among Ugandan children receiving DP for PDMC following SMA, and to evaluate how the use of DP for PDMC may influence parasite genetic diversity and the prevalence of antimalarial drug-resistance markers over time.
Specific Objectives
1. To estimate the association between P. falciparum antimalarial drug-resistance markers and malaria recurrence among Ugandan children receiving DP for PDMC following SMA.
2. To explore the association between demographic, clinical, and nutritional factors and malaria recurrence among Ugandan children receiving DP-based PDMC following severe malarial anaemia.
3. To evaluate population-level changes in P. falciparum genetic diversity between enrolment and follow-up malaria recurrence among Ugandan children on DP-based PDMC.
4. To characterize malaria recurrence as recrudescence versus reinfection among Ugandan children receiving DP for PDMC following SMA.
5. To estimate the association between baseline P. falciparum genetic diversity and the risk of malaria recurrence among Ugandan children receiving DP for PDMC following SMA.
6. To evaluate population-level changes in P. falciparum antimalarial drug-resistance markers between enrolment and follow-up malaria recurrence among children on DP-based PDMC.
Uganda 2026-08-14 19:22:14 2029-08-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Mudarshiru Bbuye
ID: UNCST-2025-R019080
Exploring the Community-led Adaptation to Climate Change-Health Risks in Urban Informal Communities in Kampala, Uganda
REFNo: HS8145ES

Main objective: To explore community perceptions of climate change–related health risks and identify community-led adaptation strategies in urban informal communities in Kampala, Uganda Specific Objectives 1. To identify existing community adaptation practices for climate change and Health hazards 2. To assess the Community Climate Health risks in selected informal communities 3. To co-develop community-led adaptation strategies for managing climate-related health risks
Uganda 2026-08-14 19:20:49 2029-08-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anthony Vodacek
ID: UNCST-2026-R025546
African Great Lakes Monitoring Program: Requirements Definition and Action Plan
REFNo: NS1373ES

The primary objectives are:
• Assess and organize existing lake data and monitoring efforts across the region.
• Identify steps for creating long-term lake monitoring networks, including priority sensor
types, communication infrastructure, and deployment strategies at a level of detail
beyond current assessments.
• Complete the system design by assessing the data and analysis workflows needed to
provide actionable guidance balancing scientific value with operational sustainability.
USA 2026-08-14 19:17:03 2029-08-14 Natural Sciences Non-Clinical Trial Non-degree Award
Racheal Nakazinga
ID: UNCST-2025-R022930
TEACHERS’ EXPERIENCES IN IMPLEMENTING THE LEARNER-CENTRED APPROACH IN ENGLISH LANGUAGE TEACHING IN SECONDARY SCHOOLS IN CENTRAL UGANDA
REFNo: SS5188ES

1. To explore teachers’ understanding of the concepts of the learner-centred approach in the English language classroom in secondary schools.
2. To examine the strategies teachers of English use in implementing the learner-centred approach in secondary schools.
3.To investigate the types of support teachers need for effective implementation of the learner-centred approach in the English language classroom in secondary schools

Uganda 2026-08-14 17:01:19 2029-08-14 Social Science and Humanities Non-Clinical Trial Degree Award
STELLA KYOYAGALA
ID:
GROWTH AND NEURODEVELOPMENTAL OUTCOMES OF PRETERM INFANTS IN SOUTH WESTERN UGANDA: A CROSSECTIONAL ASSESSMENT AT ONE YEAR OF CORRECTED AGE
REFNo: HS8396ES

General Objectives To determine the growth and neuro-developmental outcomes of preterm infants being followed up at Mbarara Regional Referral Hospital Specific Objectives 1. To determine the growth status of preterm infants at 12 months corrected age at Mbarara RRH 2. To determine the determine the developmental outcomes of preterm infants at 12 months corrected age at Mbarara RRH. 3. To determine factors associated with neurodevelopmental delay among preterm infants at Mbarara RRH.
Uganda 2026-08-13 19:52:14 2029-08-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Elke Verhaeghe Tine Leen
ID: UNCST-2026-R025001
Due Diligence Mediation in Practice: Deforestation Due Diligence in the Ugandan Coffee Sector
REFNo: SS5753ES

This study focuses on the operationalisation of the EU Regulation on Deforestation-Free Products (EUDR) in the Ugandan coffee sector. The EUDR is the latest tool in the EU’s toolbox to combat global deforestation, particularly imported deforestation. The EUDR establishes “due diligence” obligations for EU importers and traders, who are asked to prove that their goods are not linked to deforestation, forest degradation or illegal land use in the country of origin. Specifically, the EUDR applies to products from seven commodity groups identified as high-risk for deforestation, including beef, palm oil, soy, wood, cocoa, coffee and rubber (EURD, art. 2-3). The EUDR requires operators to conduct a risk-assessment on their products’ connection to deforestation or forest degradation (EUDR, arts. 8, 10) and to assume responsibility for them in a due diligence statement (EUDR, art. 4). To prove their products do not exhibit ‘non-negligible risk’ of deforestation, they need to provide the relevant authorities sufficient documentation to back their claims, including data on the geo-location of the agricultural or forest land of origin in the form of GPS coordinates or polygons (EUDR, art. 9).

Although the EUDR formally applies only to operators and traders placing products on the EU market, its effects extend far beyond EU borders. In practice, due diligence responsibilities are frequently passed up the supply chain, with significant implications for producers, traders and exporters in producer countries. As a result, questions of distributive justice and equity in EUDR operationalisation and implementation have become the subject of lively debate in the academic literature (Mcdermott et al., 2025; Verhaeghe & Ramcilovic-Suominen, 2024; Zhunusova et al., 2022). While some scholars argue that the EUDR could create opportunities for smallholders, for instance by shortening supply chains and strengthening producers’ bargaining positions (Blot & Hiller, 2022), the dominant concern remains that the regulation’s new due diligence requirements and associated transaction costs will impose additional burdens on smallholder producers and traders (Dupont, 2025) and potentially exclude them from global supply chains on which they depend (Naranjo et al., 2023; Zhunusova et al., 2022).

This study assesses activities and resources which aim to facilitate smallholder compliance with the EUDR and mitigate the EUDR’s most adverse socio-economic consequences, such as trainings, capacity building, technical support, open source technologies, and the establishment of a national digital infrastructure (Gallemore et al., 2022; Grabs et al., 2021). Focussing on the inclusion in deforestation-free value chains of smallholder farmers, micro- and smallholder traders and processors and coffee cooperatives, this study aims to understand from a bottom-up perspective how EUDR compliance is organised, mediated and experienced by upstream actors in the Ugandan coffee supply chain.

The specific study research objectives are three-fold:

OBJECTIVE 1: to understand how EUDR intermediary activities reach upstream coffee supply chain actors in Greater Masaka across different organisational and relational contexts. EUDR intermediary activities include horizontal measures, such as broad sensitisation campaigns and farmer registration initiatives intended to cover all value chain actors, and targeted measures, which are more selective and include buyer-specific registration schemes and private or donor-led traceability systems and traceability pilot projects (e.g. GIZ-supported EUDR Task Force prototype projects). Targeted activities typically focus on organised or affiliated actors, such as cooperative members or contract-linked farmers, and operate alongside more universal government- and donor-funded efforts. The study assesses whether EUDR intermediary activities reach actors evenly or unevenly across the value chain, and how different implementation modalities shape inclusion, exclusion, and disparities in compliance capacity among upstream coffee actors.

OBJECTIVE 2: to understand perceptions of upstream coffee supply chain actors about the EUDR and EUDR-related activities. Building on scoping discussions and existing reports that highlight distrust around farmer registration as a key challenge in EUDR intermediation in Central Uganda (Royalway Media, 2024; Wamala, 2025; personal communications March 2026), this study examines how trust in the EUDR and related mediation activities varies across levels of embeddedness in EUDR intermediation activities and across different organisational and relational contexts. Beyond trust as a functional concern, it also investigates broader normative perceptions, including perceived relevance of the EUDR, its contribution to sustainable coffee production, and views on responsibility and burden-sharing (Dupont & Pietrzak, 2025). In doing so, the study shifts from narrow implementation questions to bottom-up perspectives on sustainability regulation, contributing to a more decentralised and critically informed understanding of EUDR governance (Alcazar III et al., 2023; Reid & Ferrando, 2026).

OBJECTIVE 3: to understand remaining obstructions and challenges for EUDR-compliance of upstream coffee supply chain actors in practice. While prior work provides initial insights (Royalway Media, 2024), this research adds two contributions. First, it offers an independent assessment of the recently launched Task Force-led and donor-supported traceability prototyping initiatives. Second, by identifying constraints that recur across organisational, relational, and mediation contexts, the study seeks to surface structural limitations and biases in current EUDR implementation approaches. Through in-depth qualitative interviews, it examines how everyday practices and lived experiences shape, enable, or obstruct compliance in practice, thereby contributing to a grounded understanding of the EUDR’s socio-economic and environmental justice implications (McDermott et al., 2025; Verhaeghe & Ramcilovic-Suominen, 2024).
Belgium 2026-08-13 19:51:13 2029-08-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Eva Akurut
ID: UNCST-2021-R012648
BARRIERS AND ENABLERS TO WOMEN'S ADVANCEMENT IN DATA SCIENCE AND BIOINFORMATICS IN UGANDA
REFNo: SS5742ES

Primary objective: To identify barriers and enablers affecting women’s participation and advancement in emerging technology fields of Data Science and bioinformatics, with a focus on individual factors and socio-cultural, institutional, and training-related factors. Secondary objectives: ● SO1: To identify barriers and enablers at key career transition points (graduate training, early career, and leadership) and assess socio-ecological, institutional, and training-related influences on women’s participation, retention, and progression in emerging technology fields of Data Science and bioinformatics. ● SO2: To identify coping strategies, support mechanisms, and enabling factors — including the role of male allyship, mentorship, and gender attitudes—that support women’s advancement in emerging technology fields of Data Science and bioinformatics. ● SO3: To generate context-specific, evidence-based policy and practice recommendations to foster equitable participation and advancement of Ugandan women in emerging technology fields of Data Science and bioinformatics.
Uganda 2026-08-13 19:48:22 2029-08-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
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