Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Brian Mikka
ID:
Prevalence and factors associated with low-level viremia in HIV patients on NNRTIs substituted to dolutegravir-based regimen at Kitebi health center
REFNo: NS627ES

To determine the factors associated with LLV among PLHIV who were substituted to DTG-based regimens at Kitebi health centre.,To determine the prevalence of LLV among PLHIV substituted to DTG-based regimen at Kitebi health centre.,To determine the prevalence and factors associated with low-level viremia among patients substituted from NNRTIs to dolutegravir- based first-line regimen at Kitebi health centre.,
Uganda 2023-08-10 15:19:55 2026-08-10 Natural Sciences Non-Clinical Trial Degree Award
Ruth Namazzi
ID: UNCST-2020-R014305
Full Assessment of Clinical Transfusion Support (FACTS): An assessment of hematologic diseases among blood transfusion recipients and donated units at a pediatric regional referral hospital in Uganda
REFNo: HS2908ES

To determine the prevalence of SCA among children requiring blood transfusions at the children’s ward of the Jinja Regional Referral Hospital (JRRH) • To determine the prevalence of malaria parasitemia among children requiring blood transfusions at the children’s ward of the Jinja Regional Referral Hospital • To determine the prevalence of malaria parasitemia among donated, transfused blood units • To determine the incidence of iron deficiency among transfusion recipients donated, transfused blood units • To determine the RBC RhCE and Kell antigen profile on donated units and transfusion recipients
Uganda 2023-08-10 13:53:54 2026-08-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Henry Mugerwa
ID: UNCST-2019-R000420
PLATINUM: A multi-part, multi-center PLATform study to assess the efficacy, safety, tolerability and pharmacokinetics of anti-malarial agents administered as monotherapy at multiple dose levels and/or combination therapy IN patients with Uncomplicated Plasmodium falciparum Malaria
REFNo: HS2748ES

Main Objectives:
1. Part A: To assess the parasite clearance time (PCT) of oral doses of an anti- malarial agent administered as monotherapy in patients with uncomplicated P. falciparum malaria
2. Part B: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as combination therapy versus the standard of care (SoC) in patients with uncomplicated P. falciparum malaria

Secondary Objectives
1. Part A: To assess the effect on adjusted 28-day cure rate of an anti-malarial agent administered orally as monotherapy in patients with uncomplicated P. falciparum malaria
2. Part B: To assess the parasite clearance time (PCT) of oral combinations of anti-malarial agents versus SoC in patients with uncomplicated P. falciparum malaria
3. To characterize PK of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy [Part B] in patients with uncomplicated P. falciparum malaria
4. To assess the safety and tolerability of each anti-malarial agent administered orally as monotherapy [Part A] and/or as combination therapy versus SoC [Part B] in patients with uncomplicated P. falciparum malaria
Uganda 2023-08-10 13:49:44 2026-08-10 Medical and Health Sciences Clinical Trial Non-degree Award
ANITA MUHAIRWE
ID:
CORPORATE GOVERNANCE ROLES AND EMPLOYEE SATISFACTION IN HIGHER EDUCATION INSTITUTIONS: A CASE OF SELECTED PRIVATE UNIVERSITIES IN UGANDA
REFNo: NS618ES

iii. To assess the effect of corporate governance roles on employee satisfaction in selected private universities in Uganda ,ii. To analyze the contribution of work environment to employee satisfaction in selected private universities in Uganda.,i. To assess the relationship of corporate governance roles and work environment in selected private universities in Uganda. ,
Uganda 2023-08-08 15:05:06 2026-08-08 Natural Sciences Non-Clinical Trial Degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
Assessing the effect of mealworm consumption and production on nutrition and health status of children in refugee and host communities in Western Uganda, a Refugee Insect Production For Food and Feed ( RefIPro) Project
REFNo: HS3071ES

D. To assess child anthropometrics/growth and dietary intake over 6 months in preparation for a mealworm-based school meal intervention study,C. To develop a nutritious school meal enhanced with mealworm and with high acceptability among the target group of school children,B. To assess the progress of building the capacity for scaling up mealworm production including identifying local feed substrate and assess the implementation processes in the local context ,A. To assess barriers and drivers among key stakeholders (farmers, farmers associations, school heads/teachers/parents/children) of mealworm consumption and production for sale ,Improving nutrition and health of refugee and host community children through the production of mealworm,
Uganda 2023-08-08 12:45:34 2026-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Effect of an interactive SMS system in improving the reporting of adverse drug reactions among people living with HIV in Tanzania and Uganda: a randomized controlled trial: The REMIND ADR TRIAL
REFNo: HS2922ES


To investigate the effectiveness of SMS reminders on improving ADR reporting compared to no SMS among people living with HIV in Tanzania and Kampala Uganda.
To describe the most commonly reported ADR profiles among people living with HIV in Tanzania and Uganda.
To determine the most common routes/ methods of reporting ADR used by PLHIV.
To explore the causal relationship between the commonly reported ADRs and ART.
To improve treatment options for participants who reported ADR.
To explore the technical feasibility and acceptability of the intervention in reporting ADR among PLHIV.

Uganda 2023-08-08 12:42:32 2026-08-08 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE)
REFNo: HS2703ES

Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE) is a master protocol being conducted in many countries around the world, and funded by the National Institutes of Health, USA. STRIVE will evaluate the safety and effectiveness of unlicensed and licensed treatments and different combinations of treatments, to improve the health outcomes of adults
hospitalised with acute respiratory infections, like COVID-19 or influenza.
Uganda 2023-08-08 12:39:21 2026-08-08 Medical and Health Sciences Clinical Trial Non-degree Award
Mathias Gerecht
ID:
Colonialism and racism in Uganda : a study of racial speeches and policies in the Western province (1890-1962)
REFNo: SS1854ES

1. Showing which racial theories and stereotypes were developed by which colonial actors and when.
2. Understanding how these racial theories and stereotypes were developed (how was this knowledge constructed ?)
3. Analysing the various ways the Ugandan people reacted to this racism.

France 2023-08-08 12:33:56 2026-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
BARBARA NAGGAYI RITA
ID: UNCST-2019-R000062
Digital Storytelling for Global Health Research and Action
REFNo: SS1603ES

Preparing an evidence-based, practice-informed, GH focused DST package consisting of guidelines, recommendations, and innovation, which can be adapted in Phase 2 into tools and training materials for sharing with others in Canada and beyond.,
Uganda 2023-08-07 16:22:34 2026-08-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Nkangi
ID: UNCST-2021-R012153
Role and clinical significance of unconventional gamma delta T cell in cervical cancer and HIV- 1 co-infection
REFNo: HS2832ES

To assess the association of frequency and functions of γδ T cell with clinicopathological characteristics of Cervical cancer among women living with HIV infection ,To assess the cytotoxic effects of γδ T cell among women living with cervical cancer and HIV co-morbidity,To assess the immune phenotypes of the γδ T cells among women living with cervical cancer and HIV co-morbidity.,To assess the frequencies of different subsets of γδ T cells in peripheral blood among women living with cervical cancer and HIV co-infection.,To investigate the role and clinical significance of gamma delta (γδ) T cells among the women with cervical cancer and HIV co-morbidity.,
Uganda 2023-08-07 16:18:49 2026-08-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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