Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Juliet Mpendo
ID: UNCST-2024-R004147
 Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition
REFNo: HS4092ES

• To describe new HIV infections in adult and adolescent participants at risk of HIV acquisition included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Number and characteristics of new HIV infections, including detection of resistance to CAB while on study. Secondary.
Secondary Objectives
• To describe any serious adverse events (SAEs), Grade 3 and Grade 4 ISRs, and AEs leading to withdrawal in adult and adolescent participants included in the HPTN 083 and HPTN 084 studies and their associated sub-studies.
Endpoints
• Incidence and severity of serious adverse events, Grade 3 and Grade 4 ISRs, and any clinical or laboratory adverse events leading to discontinuation of CAB while on study.

 Uganda 2024-07-02 12:49:10 2027-07-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rebecca Nandutu
ID:
EXPLORING THE DEVELOPMENT OF SCIENCE PROCESS SKILLS IN THE TEACHING OF MATHEMATICS EDUCATION IN TEACHER TRAINING INSTITUTIONS IN EASTERN UGANDA
REFNo: SS2566ES


1. To assess mathematics tutor’s understanding of science process skills in teacher training institutions
2. To find out science process skills developed by mathematics tutors in teacher training institutions
3. To examine the role of mathematics tutors in developing science process skills among teacher trainees in teacher training institutions

Uganda 2024-07-02 12:46:47 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
SABRINA KITAKA BAKEERA
ID: UNCST-2020-R014290
 SEARCH2: A Randomized Control Trial of Telephonic Reminders for HPV Vaccination among Adolescent Girls in Kampala, Uganda
REFNo: HS3929ES


General Objective
To conduct a randomized control trial to assess the impact of text message and automated phone reminders on HPV vaccination.

Specific Objectives:
1.To assess the impact of text message and automated phone reminders on HPV vaccination.
Sub-objectives include:
1) To assess if text message and automated phone reminders were equally effective
2) To examine subgroup effects (girl: age, site, school status [in or out of school], grade, relationship with caregiver; caregiver: age, education, employment, income, marital status, distance to health facility, language), when possible depending on the degree of variability observed
3) to assess for possible additive or subtractive effects of receiving two series of message for families of girls who may have been in the intervention for both initiation and completion

Uganda 2024-07-02 12:45:18 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
Elizabeth namukwaya namukwaya
ID: UNCST-2021-R013177
 PARASTOP-Paracetamol with strong opioids
REFNo: HS4423ES

To explore whether placebo with strong opioids compared to paracetamol with strong opioids changes pain intenisty for different doses of opioids, different cancers and quality of lifeintensity,To establish whether placebo with strong opioids compared to paracetamol with strong opioids changes opioid related side-effects,changes in opioid requirements and global rating of improvement,To establish whether placebo with strong opioids compared to paracetamol together with strong opioids provides non-inferior analgesia for cancer related pain,To establish whether the analgesic efficacy of strong opioids after withdrawal of paracetamol is non-inferior compared the analgesic efficacy of strong opioids used together with paracetamol for cancer-related pain.,
 Uganda 2024-07-02 12:41:56 2027-07-02 Medical and Health Sciences Clinical Trial Non-degree Award
ANNY KATABAAZI  BWENGYE
ID:
GOVERNING BODIES’ FUNCTION AND PUBLIC UNIVERSITY FINANCING IN UGANDA: A CASE OF SELECTED UNIVERSITIES
REFNo: SS2708ES

1) To assess how the Adequacy and Allocative Efficiency function affects of public university financing.
2) To examine the relationship between the governing bodies’ policy function and pattern of public university financing.
3) To examine how the governing bodies’ financial function influences public university financing.
4) To determine the extent to which the governing bodies’ technical function influences public university financing.
5) To examine the challenges facing governing bodies in enhancing public university financing.
 Uganda 2024-07-02 12:40:29 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 Pediatric HIV Status Disclosure: Mental Health Outcomes, Barriers and Facilitators and Feasibility and Acceptability of Training Intervention in Improving Healthcare Workers’ Knowledge in Eastern Uganda.
REFNo: HS4017ES

1. To determine the prevalence of HIV status disclosure and association with mental health outcomes among CYALH in eastern Uganda. 2. To explore the experiences and coping mechanisms after HIV status disclosure after HIV status disclosure among young adolescents living with HIV in eastern Uganda 3. To explore the barriers and facilitators to HIV status disclosure to CYALH experienced by Healthcare workers (HCWs) in eastern Uganda . 4. To pilot and assess the feasibility and acceptability of a training intervention using WHO HIV status disclosure guidelines among HCWs to improve their knowledge about disclosure.
 Uganda 2024-07-02 12:35:50 2027-07-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Robert Kairania
ID: UNCST-2024-R016014
 Optimizing adoption and implementation of out-of-facility and clinic-based differentiated service delivery models for HIV treatment in Uganda: the OPTIONS study
REFNo: SS2776ES

Aim 1: Quantify individual-level and geographic variations in uptake of out-of-facility and clinic-based DSDM in 34 continuously surveilled communities. Approach: Using existing/secondary data from the Rakai Community Cohort Study.
Aim 2: Explore decision-making contexts and pathways to patient enrollment in out-of-facility and clinic-based differentiated HIV care models, as well as contextual and institutional determinants of DSDM adoption at clinic level.

Sub-Aim 2a: Identify modifiable conditions or mechanisms optimizing DSDM adoption in a heterogenous sample of HIV clinics.

Uganda 2024-07-02 12:33:52 2027-07-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Nseka Kiyaga
ID:
The Role of Internal Audit on the Governance of Regulated Non-Deposit-Taking Microfinance Institutions in Uganda
REFNo: SS2778ES

iii) To construct an applied framework that may inform recommendations to institutionalize internal audits among regulated NDTMFIs in Uganda,ii) To examine the nexus within the academic literature on theories relating to corporate governance, internal audit, and microfinance,i) To investigate the role of internal audit on the governance of regulated NDTMFIs in Uganda,
 Uganda 2024-07-02 12:31:38 2027-07-02 Social Science and Humanities Non-Clinical Trial Degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2500™) in Detecting Intracranial Hemorrhage in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS4141ES

Use these findings to evaluate the InfraScanner 2500™\'s ability to accurately detect intracranial hemorrhages in darker-skinned populations within LMICs. ,Determine whether the InfraScanner 2500™ detects intracranial hemorrhage (ICH) with adequate precision relative to CT scans to be used as an effective triage tool to prioritize imaging and need for level of clinical monitoring in an African, LMIC population.,To demonstrate that the InfraScanner 2500™ is capable of detecting and ruling out intracranial hematomas at rates similar to CT scan in patients hospitalized at Mbarara Regional Referral Hospital who have sustained or are suspected to have sustained head trauma.,
 Uganda 2024-06-24 0:30:16 2027-06-24 Medical and Health Sciences Clinical Trial Non-degree Award
Kirabo Suubi
ID: UNCST-2023-R005659
 Making Social Protection Interventions Work for Marginalized Women in Kenya and Uganda: Understanding the state of research evidence, women’s preferences, and policymakers’ challenges in relation to Social Protection
REFNo: SS2785ES

To understand Ugandan and Kenyan policymakers’ experiences of designing and implementing SP programs and policies as well as their evidence needs related to SP.,To understand vulnerable Kenyan and Ugandan women’s perceptions of existing SP programs in their countries, and how they think SP initiatives can be best designed and delivered to them.,To synthesize findings of previous studies on the ingredients of effective SP interventions for women. ,
 Uganda 2024-06-24 0:28:26 2027-06-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
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